CRCGN008_HEPG2_24H:G17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description withaferin-a 1.25 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

388 genes differentially expressed following the CRCGN008_HEPG2_24H:G17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABHD4 abhydrolase domain containing 4 10.0
TXNRD1 thioredoxin reductase 1 8.7138
HMOX1 heme oxygenase 1 8.56195
TIMP2 TIMP metallopeptidase inhibitor 2 6.9807
CDPF1 cysteine-rich, DPF motif domain containing 1 6.47865
H2BC12 H2B clustered histone 12 6.394
ALAS1 5'-aminolevulinate synthase 1 6.1396
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 5.66455
UGDH UDP-glucose 6-dehydrogenase 5.4264
CNPY3 canopy FGF signaling regulator 3 5.41165
HLA-DMA major histocompatibility complex, class II, DM alpha 5.27665
FOSL1 FOS-like antigen 1 5.26345
NPDC1 neural proliferation, differentiation and control, 1 5.03125
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 4.99515
SQSTM1 sequestosome 1 4.94543
DYNLT3 dynein, light chain, Tctex-type 3 4.9332
CCL2 chemokine (C-C motif) ligand 2 4.7636
NR1H2 nuclear receptor subfamily 1, group H, member 2 4.52385
C2CD2 C2 calcium-dependent domain containing 2 4.50055
EGF epidermal growth factor 4.4798
KLHL21 kelch-like family member 21 4.42835
ADI1 acireductone dioxygenase 1 4.42255
PRR15L proline rich 15-like 4.4037
TBC1D31 TBC1 domain family, member 31 4.3498
MCOLN1 mucolipin 1 4.31835
CCP110 centriolar coiled coil protein 110kDa 4.2679
GARRE1 granule associated Rac and RHOG effector 1 4.17555
ABHD6 abhydrolase domain containing 6 4.09468
BAG3 BCL2-associated athanogene 3 4.0047
CDCA4 cell division cycle associated 4 3.90045
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 3.8823
MVP major vault protein 3.8715
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 3.8064
PARP2 poly (ADP-ribose) polymerase 2 3.7808
TXNL4B thioredoxin-like 4B 3.74005
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.7398
GADD45A growth arrest and DNA-damage-inducible, alpha 3.7261
CDC45 cell division cycle 45 3.65745
CIAO3 cytosolic iron-sulfur assembly component 3 3.6516
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 3.6112
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 3.595
CYCS cytochrome c, somatic 3.5322
TUBB6 tubulin, beta 6 class V 3.51255
KEAP1 kelch-like ECH-associated protein 1 3.49235
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 3.3964
TMEM109 transmembrane protein 109 3.36915
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 3.3649
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 3.30915
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 3.2851
H2BC21 H2B clustered histone 21 3.2651
MAP7 microtubule-associated protein 7 3.25843
ANO10 anoctamin 10 3.2485
PMM2 phosphomannomutase 2 3.215
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 3.2055
GPC1 glypican 1 3.16045
TUT7 terminal uridylyl transferase 7 3.0862
NOSIP nitric oxide synthase interacting protein 3.0395
CDK19 cyclin-dependent kinase 19 3.01812
KIF5C kinesin family member 5C 3.00423
CHN1 chimerin 1 2.95835
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.9253
CBR1 carbonyl reductase 1 2.9075
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 2.8586
ECD ecdysoneless homolog (Drosophila) 2.8467
TERF2IP telomeric repeat binding factor 2, interacting protein 2.7625
SMIM40 small integral membrane protein 40 2.7474
STXBP1 syntaxin binding protein 1 2.72575
EXO1 exonuclease 1 2.72075
TMEM50A transmembrane protein 50A 2.68745
TMEM158 transmembrane protein 158 (gene/pseudogene) 2.6816
TATDN2 TatD DNase domain containing 2 2.6705
BLCAP bladder cancer associated protein 2.65335
PRDM13 PR domain containing 13 2.6397
PELO pelota homolog (Drosophila) 2.63845
HSPA1A heat shock 70kDa protein 1A 2.63765
EFL1 elongation factor like GTPase 1 2.63515
H2BC17 H2B clustered histone 17 2.6316
AP1B1 adaptor-related protein complex 1, beta 1 subunit 2.6142
CYBRD1 cytochrome b reductase 1 2.579
SSBP2 single-stranded DNA binding protein 2 2.56678
IL37 interleukin 37 2.56585
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.55608
CLEC16A C-type lectin domain family 16, member A 2.54645
CSRP2 cysteine and glycine-rich protein 2 2.51102
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.47495
NDC80 NDC80 kinetochore complex component 2.47155
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.469
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 2.4518
PLEKHA8 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 2.4432
LYN LYN proto-oncogene, Src family tyrosine kinase 2.43265
PAQR5 progestin and adipoQ receptor family member V 2.4312
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 2.4309
MICALL1 MICAL-like 1 2.4305
TCP11 t-complex 11, testis-specific 2.4278
ADRM1 adhesion regulating molecule 1 2.41885
TBC1D15 TBC1 domain family, member 15 2.41105
BANP BTG3 associated nuclear protein 2.40645
CTSL cathepsin L 2.3962
TEX12 testis expressed 12 2.3898
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 2.38565
GSR glutathione reductase 2.37845
NPBWR2 neuropeptides B/W receptor 2 2.36515
PEA15 phosphoprotein enriched in astrocytes 15 2.358
RASAL2 RAS protein activator like 2 2.3572
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 2.35315
ANTXR1 anthrax toxin receptor 1 2.34415
CDK5RAP2 CDK5 regulatory subunit associated protein 2 2.3419
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 2.3254
FKBP4 FK506 binding protein 4, 59kDa 2.31585
GPR63 G protein-coupled receptor 63 2.30695
TMEM134 transmembrane protein 134 2.30465
RALB v-ral simian leukemia viral oncogene homolog B 2.30272
CRYBA1 crystallin, beta A1 2.2906
CENPQ centromere protein Q 2.27715
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 2.27399
PCDH17 protocadherin 17 2.27015
ADGB androglobin 2.2641
P3H2 prolyl 3-hydroxylase 2 2.26265
ZNF674 zinc finger protein 674 2.26175
PRND prion protein 2 (dublet) 2.25855
GPR15 G protein-coupled receptor 15 2.2558
HSPB8 heat shock 22kDa protein 8 2.2523
ATP11B ATPase, class VI, type 11B 2.2443
PPP1R13B protein phosphatase 1, regulatory subunit 13B 2.24035
DNAL4 dynein, axonemal, light chain 4 2.23875
FPGS folylpolyglutamate synthase 2.2381
SPATA17 spermatogenesis associated 17 2.2341
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.2317
GLIPR1 GLI pathogenesis-related 1 2.22818
MTERF4 mitochondrial transcription termination factor 4 2.2266
TLK2 tousled-like kinase 2 2.22385
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 2.22305
RAD21L1 RAD21-like 1 (S. pombe) 2.2171
GALP galanin-like peptide 2.21635
SMG9 SMG9 nonsense mediated mRNA decay factor 2.2143
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 2.2084
DIAPH3 diaphanous-related formin 3 2.20565
PFDN2 prefoldin subunit 2 2.20255
CFAP46 cilia and flagella associated protein 46 2.2025
ELL2 elongation factor, RNA polymerase II, 2 2.19605
PITPNM3 PITPNM family member 3 2.1893
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 2.189
IKZF3 IKAROS family zinc finger 3 (Aiolos) 2.18815
RNASE7 ribonuclease, RNase A family, 7 2.186
RAB21 RAB21, member RAS oncogene family 2.1779
ATG101 autophagy related 101 2.17715
WBP2 WW domain binding protein 2 2.1764
WNT3 wingless-type MMTV integration site family, member 3 2.1726
CSF1R colony stimulating factor 1 receptor 2.1655
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.1625
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2 2.15425
TLR7 toll-like receptor 7 2.15175
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 2.14825
IMPG1 interphotoreceptor matrix proteoglycan 1 2.14225
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough 2.13475
PPME1 protein phosphatase methylesterase 1 2.13345
DMRT1 doublesex and mab-3 related transcription factor 1 2.1315
ZNF391 zinc finger protein 391 2.13055
PURG purine-rich element binding protein G 2.12385
AGBL3 ATP/GTP binding protein-like 3 2.12085
LDHAL6B lactate dehydrogenase A-like 6B 2.1188
KRT36 keratin 36, type I 2.11575
SPO11 SPO11 meiotic protein covalently bound to DSB 2.11575
CCDC169-SOHLH2 CCDC169-SOHLH2 readthrough 2.10465
VAT1 vesicle amine transport 1 2.10395
RAI14 retinoic acid induced 14 2.10285
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 2.09875
TTLL7 tubulin tyrosine ligase-like family member 7 2.0944
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.08542
PAPOLB poly(A) polymerase beta (testis specific) 2.08495
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 2.0821
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 2.0798
H2BC9 H2B clustered histone 9 2.07915
TGIF1 TGFB-induced factor homeobox 1 2.07845
ASF1A anti-silencing function 1A histone chaperone 2.0775
SCPEP1 serine carboxypeptidase 1 2.0745
LGALSL lectin, galactoside-binding-like 2.0726
RFPL1 ret finger protein-like 1 2.0678
MAGIX MAGI family member, X-linked 2.06385
USP11 ubiquitin specific peptidase 11 2.0599
ZNF80 zinc finger protein 80 2.0598
YARS1 tyrosyl-tRNA synthetase 1 2.05955
PF4V1 platelet factor 4 variant 1 2.05315
OR11A1 olfactory receptor, family 11, subfamily A, member 1 2.0531
NPVF neuropeptide VF precursor 2.0474
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2.04555
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.03177
GCM2 glial cells missing homolog 2 (Drosophila) 2.02575
COPS5 COP9 signalosome subunit 5 2.02395
TMOD2 tropomodulin 2 (neuronal) 2.02385
ZNF81 zinc finger protein 81 2.02315
NPTXR neuronal pentraxin receptor 2.0227
TLR4 toll-like receptor 4 2.0218
TSGA10 testis specific, 10 2.01715
STON1-GTF2A1L STON1-GTF2A1L readthrough 2.01225
MMP2 matrix metallopeptidase 2 2.0121
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 2.01125
KNL1 kinetochore scaffold 1 2.0098
ZBTB6 zinc finger and BTB domain containing 6 2.0076
SPICE1 spindle and centriole associated protein 1 2.00545
ADAM18 ADAM metallopeptidase domain 18 2.00485
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 2.00475
ADRA1B adrenoceptor alpha 1B 2.0044
RMC1 regulator of MON1-CCZ1 2.0018

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -10.0
PCCB propionyl CoA carboxylase, beta polypeptide -10.0
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -8.3983
C5 complement component 5 -7.33745
INTS3 integrator complex subunit 3 -6.62335
ICAM3 intercellular adhesion molecule 3 -5.93145
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -5.78875
B4GAT1 beta-1,4-glucuronyltransferase 1 -5.65305
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -5.53315
PCNA proliferating cell nuclear antigen -5.5235
OXA1L oxidase (cytochrome c) assembly 1-like -5.498
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -5.47265
ACAA1 acetyl-CoA acyltransferase 1 -5.34113
C2CD5 C2 calcium-dependent domain containing 5 -5.1837
NNT nicotinamide nucleotide transhydrogenase -4.99925
ZNF586 zinc finger protein 586 -4.4959
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -4.3726
ISOC1 isochorismatase domain containing 1 -4.312
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.29775
COG2 component of oligomeric golgi complex 2 -4.2847
CDK1 cyclin-dependent kinase 1 -4.2373
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -4.1949
DCK deoxycytidine kinase -4.13365
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -4.1213
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -4.0875
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -3.9649
NISCH nischarin -3.88665
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -3.86442
TOP2A topoisomerase (DNA) II alpha 170kDa -3.7615
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -3.69065
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -3.67275
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.6721
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -3.6471
PECR peroxisomal trans-2-enoyl-CoA reductase -3.62925
ACOT9 acyl-CoA thioesterase 9 -3.5999
ZNF587 zinc finger protein 587 -3.50735
TSPAN4 tetraspanin 4 -3.4734
PROS1 protein S (alpha) -3.4481
CCNB2 cyclin B2 -3.4379
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -3.41375
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -3.41118
FGFR4 fibroblast growth factor receptor 4 -3.3814
ILK integrin-linked kinase -3.3511
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 -3.34675
GET1 guided entry of tail-anchored proteins factor 1 -3.22505
CRK v-crk avian sarcoma virus CT10 oncogene homolog -3.21957
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -3.20285
NRIP1 nuclear receptor interacting protein 1 -3.18358
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa -3.13265
TMEM168 transmembrane protein 168 -3.09325
PGM1 phosphoglucomutase 1 -3.07915
CROT carnitine O-octanoyltransferase -2.9438
HSPA8 heat shock 70kDa protein 8 -2.94045
RELN reelin -2.91905
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 -2.88755
HMGA2 high mobility group AT-hook 2 -2.84545
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -2.8326
MINDY1 MINDY lysine 48 deubiquitinase 1 -2.8321
ITGB1BP1 integrin beta 1 binding protein 1 -2.82142
TMEM106C transmembrane protein 106C -2.793
PDF peptide deformylase (mitochondrial) -2.78765
STAT1 signal transducer and activator of transcription 1, 91kDa -2.76143
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa -2.746
FGL1 fibrinogen-like 1 -2.72985
TSPAN6 tetraspanin 6 -2.70813
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.686
EXT1 exostosin glycosyltransferase 1 -2.67772
RPS27A ribosomal protein S27a -2.67055
RPS9 ribosomal protein S9 -2.66585
DUSP6 dual specificity phosphatase 6 -2.66528
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha -2.66185
NT5DC2 5'-nucleotidase domain containing 2 -2.65035
MRPS16 mitochondrial ribosomal protein S16 -2.63555
TXNDC9 thioredoxin domain containing 9 -2.60112
TOMM70 translocase of outer mitochondrial membrane 70 -2.58228
SPAG7 sperm associated antigen 7 -2.5799
ATP5MC3 ATP synthase membrane subunit c locus 3 -2.5726
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -2.55335
MYLK myosin light chain kinase -2.53505
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.51963
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -2.50165
DMAC2L distal membrane arm assembly component 2 like -2.49653
STXBP2 syntaxin binding protein 2 -2.4858
TCERG1 transcription elongation regulator 1 -2.48575
AHSG alpha-2-HS-glycoprotein -2.4704
F7 coagulation factor VII (serum prothrombin conversion accelerator) -2.44635
GLI1 GLI family zinc finger 1 -2.44525
SUOX sulfite oxidase -2.4427
CDK4 cyclin-dependent kinase 4 -2.42875
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.4247
TRAPPC4 trafficking protein particle complex 4 -2.41628
ZNF606 zinc finger protein 606 -2.4132
RPL10A ribosomal protein L10a -2.4042
STMN1 stathmin 1 -2.3804
GPR137B G protein-coupled receptor 137B -2.37145
RABL3 RAB, member of RAS oncogene family-like 3 -2.36865
PLS1 plastin 1 -2.3681
MAPK13 mitogen-activated protein kinase 13 -2.36732
FOS FBJ murine osteosarcoma viral oncogene homolog -2.36285
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 -2.35565
CHMP4B charged multivesicular body protein 4B -2.33115
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -2.3302
CATSPERH catsper channel auxiliary subunit eta -2.3253
RNF167 ring finger protein 167 -2.3178
TCEAL4 transcription elongation factor A (SII)-like 4 -2.3136
HSPB2 heat shock 27kDa protein 2 -2.31175
TM4SF5 transmembrane 4 L six family member 5 -2.30545
PRPF4 pre-mRNA processing factor 4 -2.3053
TRMT5 tRNA methyltransferase 5 -2.3028
PILRB paired immunoglobin-like type 2 receptor beta -2.2937
NIT2 nitrilase family, member 2 -2.29125
SOAT2 sterol O-acyltransferase 2 -2.28758
ATP5F1A ATP synthase F1 subunit alpha -2.28745
NIP7 NIP7, nucleolar pre-rRNA processing protein -2.2844
GSTM2 glutathione S-transferase mu 2 (muscle) -2.2811
TTC38 tetratricopeptide repeat domain 38 -2.27025
AHCY adenosylhomocysteinase -2.26305
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -2.25605
STAMBP STAM binding protein -2.2553
KLHDC2 kelch domain containing 2 -2.2536
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -2.24367
RSU1 Ras suppressor protein 1 -2.2417
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -2.2308
MEGF8 multiple EGF-like-domains 8 -2.2302
CCNA2 cyclin A2 -2.22907
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) -2.223
ERBB3 erb-b2 receptor tyrosine kinase 3 -2.2193
RPL21 ribosomal protein L21 -2.2176
SPTAN1 spectrin, alpha, non-erythrocytic 1 -2.21492
HOXB3 homeobox B3 -2.2106
RBFA ribosome binding factor A (putative) -2.1876
BZW1 basic leucine zipper and W2 domains 1 -2.18733
RGN regucalcin -2.185
POM121 POM121 transmembrane nucleoporin -2.18025
MMD monocyte to macrophage differentiation-associated -2.1796
CRTAP cartilage associated protein -2.178
AMBP alpha-1-microglobulin/bikunin precursor -2.17075
TSPAN31 tetraspanin 31 -2.1697
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -2.1587
RBP4 retinol binding protein 4, plasma -2.15625
PRSS2 protease, serine, 2 (trypsin 2) -2.15455
RPS5 ribosomal protein S5 -2.15185
RPS8 ribosomal protein S8 -2.14805
RBM3 RNA binding motif (RNP1, RRM) protein 3 -2.1461
MAGT1 magnesium transporter 1 -2.1431
MECR mitochondrial trans-2-enoyl-CoA reductase -2.1172
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -2.1107
ADNP activity-dependent neuroprotector homeobox -2.10985
PTPN6 protein tyrosine phosphatase, non-receptor type 6 -2.108
EOLA1 endothelium and lymphocyte associated ASCH domain 1 -2.1073
HNMT histamine N-methyltransferase -2.10678
ARF5 ADP-ribosylation factor 5 -2.1066
CPNE7 copine VII -2.09645
APEH acylaminoacyl-peptide hydrolase -2.08885
METTL9 methyltransferase like 9 -2.0869
CCNL2 cyclin L2 -2.085
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -2.07775
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -2.07643
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -2.06398
RINT1 RAD50 interactor 1 -2.05875
TTLL3 tubulin tyrosine ligase-like family member 3 -2.05688
IGF2 insulin-like growth factor 2 -2.0556
EIF3K eukaryotic translation initiation factor 3, subunit K -2.05455
CFHR2 complement factor H-related 2 -2.05405
VTN vitronectin -2.0524
RPS25 ribosomal protein S25 -2.0474
FGF17 fibroblast growth factor 17 -2.04685
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H') -2.0457
DPH2 DPH2 homolog (S. cerevisiae) -2.0434
NUDCD3 NudC domain containing 3 -2.03445
SYT2 synaptotagmin II -2.03225
PNKP polynucleotide kinase 3'-phosphatase -2.0311
TMED7 transmembrane emp24 protein transport domain containing 7 -2.02968
CS citrate synthase -2.02815
CRYL1 crystallin, lambda 1 -2.0216
NUBPL nucleotide binding protein-like -2.02025
LRRC20 leucine rich repeat containing 20 -2.0167
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -2.01355
RWDD2B RWD domain containing 2B -2.0112
PTCH2 patched 2 -2.0073
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -2.0064
SLC7A10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 -2.0043
HP1BP3 heterochromatin protein 1, binding protein 3 -2.00395
POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3 -2.00207