| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | c.i. acid orange 10 20.1 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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65 genes differentially expressed following the CRCGN008_HEPG2_24H:G20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 9.0698 |
| UBQLN2 | ubiquilin 2 | 5.14695 |
| ARL4C | ADP-ribosylation factor-like 4C | 5.07562 |
| TAC4 | tachykinin 4 (hemokinin) | 5.0 |
| NOTCH1 | notch 1 | 4.9698 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.74275 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.6906 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 4.5794 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 4.192 |
| CCNA1 | cyclin A1 | 4.1308 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.77265 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 3.42345 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.21802 |
| MAP7 | microtubule-associated protein 7 | 3.02868 |
| CCNF | cyclin F | 2.7658 |
| EDN1 | endothelin 1 | 2.69705 |
| JADE2 | jade family PHD finger 2 | 2.63173 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.596 |
| KLHL9 | kelch-like family member 9 | 2.5323 |
| EPHA3 | EPH receptor A3 | 2.50663 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 2.4908 |
| GATA2 | GATA binding protein 2 | 2.45675 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.39213 |
| H2BC21 | H2B clustered histone 21 | 2.37905 |
| CORO1A | coronin, actin binding protein, 1A | 2.31175 |
| ENTREP2 | endosomal transmembrane epsin interactor 2 | 2.24865 |
| STXBP2 | syntaxin binding protein 2 | 2.2301 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 2.2231 |
| POGLUT1 | protein O-glucosyltransferase 1 | 2.2216 |
| UGT1A8 | UDP glucuronosyltransferase 1 family, polypeptide A8 | 2.1716 |
| FOXJ3 | forkhead box J3 | 2.15313 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 2.1124 |
| TXNL4B | thioredoxin-like 4B | 2.104 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 2.08795 |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 | 2.08765 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D | 2.00155 |
| Symbol | Name | Standardized Value |
|---|---|---|
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.00105 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -5.8109 |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 | -5.4797 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -5.27485 |
| COG4 | component of oligomeric golgi complex 4 | -4.9631 |
| DNM1L | dynamin 1-like | -4.78675 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.6796 |
| CCNB2 | cyclin B2 | -4.551 |
| VDAC1 | voltage-dependent anion channel 1 | -4.50128 |
| GNAS | GNAS complex locus | -3.80128 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -3.69745 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -3.59675 |
| HMG20B | high mobility group 20B | -3.56423 |
| TWF2 | twinfilin actin binding protein 2 | -3.46465 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -3.41838 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.34872 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.0407 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.02105 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -2.8269 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.55378 |
| PEG10 | paternally expressed 10 | -2.5 |
| SAA4 | serum amyloid A4, constitutive | -2.2811 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -2.20195 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -2.17755 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.1459 |
| SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 | -2.05525 |
| MPHOSPH10 | M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) | -2.04565 |
| CCNL1 | cyclin L1 | -2.0214 |
| ALS2CL | ALS2 C-terminal like | -2.00345 |
