| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | c.i. acid orange 10 2.51 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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65 genes differentially expressed following the CRCGN008_HEPG2_24H:G23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EVL | Enah/Vasp-like | 6.1272 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 5.7817 |
| CHMP6 | charged multivesicular body protein 6 | 4.8496 |
| CCNA1 | cyclin A1 | 4.7341 |
| ALDOC | aldolase C, fructose-bisphosphate | 4.7279 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.6629 |
| STIMATE | STIM activating enhancer | 4.60635 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.50535 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.4311 |
| EGF | epidermal growth factor | 4.2766 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 3.91063 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.8503 |
| SFTPB | surfactant protein B | 3.69615 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.64565 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.1768 |
| VGLL4 | vestigial-like family member 4 | 2.9068 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.89638 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.807 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.63692 |
| CCNF | cyclin F | 2.62188 |
| BZW2 | basic leucine zipper and W2 domains 2 | 2.6177 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.52575 |
| UBFD1 | ubiquitin family domain containing 1 | 2.32795 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 2.29077 |
| PTK2 | protein tyrosine kinase 2 | 2.26958 |
| NIBAN1 | niban apoptosis regulator 1 | 2.26898 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.2666 |
| COPS4 | COP9 signalosome subunit 4 | 2.227 |
| GATA2 | GATA binding protein 2 | 2.17212 |
| C1S | complement component 1, s subcomponent | 2.14395 |
| TXNL4B | thioredoxin-like 4B | 2.12825 |
| NUCB2 | nucleobindin 2 | 2.11265 |
| SLC75A1 | solute carrier family 75 member 1 | 2.0765 |
| CEP57 | centrosomal protein 57kDa | 2.00694 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TLCD3A | TLC domain containing 3A | -8.74405 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -5.559 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -5.3095 |
| FASTKD5 | FAST kinase domains 5 | -5.15465 |
| LOC124907782 | dual specificity protein phosphatase 22 | -5.0776 |
| LDHD | lactate dehydrogenase D | -4.941 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -4.7555 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -4.59777 |
| CDC20 | cell division cycle 20 | -4.3123 |
| MAPK13 | mitogen-activated protein kinase 13 | -4.0032 |
| GLOD4 | glyoxalase domain containing 4 | -3.8002 |
| PRPF4 | pre-mRNA processing factor 4 | -3.68855 |
| HDAC2 | histone deacetylase 2 | -3.6851 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.4152 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.91845 |
| TOR1A | torsin family 1, member A (torsin A) | -2.86435 |
| RHOB | ras homolog family member B | -2.6059 |
| MAP7 | microtubule-associated protein 7 | -2.60113 |
| CCP110 | centriolar coiled coil protein 110kDa | -2.50815 |
| RBM6 | RNA binding motif protein 6 | -2.50745 |
| PDZD2 | PDZ domain containing 2 | -2.46352 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.31883 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.2847 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -2.2078 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 | -2.1981 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | -2.0959 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -2.08815 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.04352 |
| TOP6BL | TOP6B like initiator of meiotic double strand breaks | -2.0373 |
| PAIP2B | poly(A) binding protein interacting protein 2B | -2.03655 |
| NVL | nuclear VCP-like | -2.01235 |
