CRCGN008_HEPG2_24H:H02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description p-rosaniline.hcl 20.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

1054 genes differentially expressed following the CRCGN008_HEPG2_24H:H02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
INPP1 inositol polyphosphate-1-phosphatase 10.0
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
TXNRD1 thioredoxin reductase 1 10.0
TRIB3 tribbles pseudokinase 3 9.8468
FHL2 four and a half LIM domains 2 9.1601
LRP10 low density lipoprotein receptor-related protein 10 8.824
ZFP36 ZFP36 ring finger protein 8.76935
TIMP2 TIMP metallopeptidase inhibitor 2 8.68595
MYC v-myc avian myelocytomatosis viral oncogene homolog 8.16445
DDIT4 DNA-damage-inducible transcript 4 7.8404
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 7.7668
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 7.65175
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 7.36645
BZW2 basic leucine zipper and W2 domains 2 7.23755
FOSL1 FOS-like antigen 1 7.09985
STX1A syntaxin 1A (brain) 6.7871
GFPT1 glutamine--fructose-6-phosphate transaminase 1 6.6109
ANO1 anoctamin 1, calcium activated chloride channel 6.5871
IGFBP3 insulin-like growth factor binding protein 3 6.50077
MICALL1 MICAL-like 1 6.3076
IER3 immediate early response 3 6.2833
CAB39 calcium binding protein 39 6.1826
LCN2 lipocalin 2 6.1398
CHN1 chimerin 1 5.9884
IL4R interleukin 4 receptor 5.93455
ACOT9 acyl-CoA thioesterase 9 5.8912
LSR lipolysis stimulated lipoprotein receptor 5.86585
KIFBP kinesin family binding protein 5.81605
VAT1 vesicle amine transport 1 5.7904
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 5.7805
STAP2 signal transducing adaptor family member 2 5.63985
CCDC92 coiled-coil domain containing 92 5.4989
SQSTM1 sequestosome 1 5.49123
PTPN12 protein tyrosine phosphatase, non-receptor type 12 5.3471
DSG2 desmoglein 2 5.3308
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 5.30725
NR1H2 nuclear receptor subfamily 1, group H, member 2 5.3035
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 5.29645
EGF epidermal growth factor 5.2726
SLC35F2 solute carrier family 35, member F2 5.24135
GFOD1 glucose-fructose oxidoreductase domain containing 1 5.20715
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 5.13155
CCL2 chemokine (C-C motif) ligand 2 5.0714
SMAD3 SMAD family member 3 5.04211
EGR1 early growth response 1 4.83957
NPDC1 neural proliferation, differentiation and control, 1 4.81235
MVP major vault protein 4.8067
KLHL21 kelch-like family member 21 4.80225
SQOR sulfide quinone oxidoreductase 4.76015
CHIC2 cysteine-rich hydrophobic domain 2 4.70525
CASC3 cancer susceptibility candidate 3 4.6523
RGS2 regulator of G-protein signaling 2 4.60725
MBNL2 muscleblind-like splicing regulator 2 4.59375
LPAR2 lysophosphatidic acid receptor 2 4.566
TES testin LIM domain protein 4.52445
ARL4C ADP-ribosylation factor-like 4C 4.50782
TRIB1 tribbles pseudokinase 1 4.50165
SNAP25 synaptosomal-associated protein, 25kDa 4.42453
EVL Enah/Vasp-like 4.39855
BDH1 3-hydroxybutyrate dehydrogenase, type 1 4.33605
AARS1 alanyl-tRNA synthetase 1 4.31995
NANOS3 nanos homolog 3 (Drosophila) 4.287
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 4.27845
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 4.24195
MCUR1 mitochondrial calcium uniporter regulator 1 4.20525
GTPBP2 GTP binding protein 2 4.1959
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 4.18335
PPARD peroxisome proliferator-activated receptor delta 4.1768
PRAF2 PRA1 domain family, member 2 4.1166
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 4.09545
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 4.0517
RFC2 replication factor C (activator 1) 2, 40kDa 4.0494
TOMM34 translocase of outer mitochondrial membrane 34 4.0214
NUP58 nucleoporin 58 3.9937
YARS1 tyrosyl-tRNA synthetase 1 3.98575
MAP7 microtubule-associated protein 7 3.98472
RALB v-ral simian leukemia viral oncogene homolog B 3.95417
E2F2 E2F transcription factor 2 3.91125
NPC1 Niemann-Pick disease, type C1 3.87402
NOTCH1 notch 1 3.8562
SOX4 SRY (sex determining region Y)-box 4 3.84711
CXCR4 chemokine (C-X-C motif) receptor 4 3.82185
RAB11FIP2 RAB11 family interacting protein 2 (class I) 3.77175
ATF6 activating transcription factor 6 3.7674
MYH9 myosin, heavy chain 9, non-muscle 3.7569
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 3.7411
ASCC3 activating signal cointegrator 1 complex subunit 3 3.7341
ANKRD10 ankyrin repeat domain 10 3.73005
PXDC1 PX domain containing 1 3.6862
TERF2IP telomeric repeat binding factor 2, interacting protein 3.6652
ABHD4 abhydrolase domain containing 4 3.65525
ATF4 activating transcription factor 4 3.65215
IFRD1 interferon-related developmental regulator 1 3.58573
JOSD1 Josephin domain containing 1 3.5807
SH3GLB1 SH3-domain GRB2-like endophilin B1 3.57785
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 3.5735
MACF1 microtubule-actin crosslinking factor 1 3.55555
PPARG peroxisome proliferator-activated receptor gamma 3.54475
CDK7 cyclin-dependent kinase 7 3.5392
PDGFA platelet-derived growth factor alpha polypeptide 3.52713
TEAD3 TEA domain family member 3 3.5184
ALAS1 5'-aminolevulinate synthase 1 3.4991
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 3.48645
PRKCD protein kinase C, delta 3.4746
FBXO7 F-box protein 7 3.45555
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 3.45407
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 3.3999
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 3.39225
GARS1 glycyl-tRNA synthetase 1 3.3713
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 3.36305
KAT6A K(lysine) acetyltransferase 6A 3.3318
PHKA1 phosphorylase kinase, alpha 1 (muscle) 3.32165
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 3.31915
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 3.3023
TP53BP2 tumor protein p53 binding protein 2 3.299
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 3.24845
SARS1 seryl-tRNA synthetase 1 3.24205
CSNK1E casein kinase 1, epsilon 3.22032
RB1CC1 RB1-inducible coiled-coil 1 3.20508
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 3.19695
SYNGR3 synaptogyrin 3 3.19685
GRB10 growth factor receptor-bound protein 10 3.18398
CSRNP2 cysteine-serine-rich nuclear protein 2 3.18235
SNX6 sorting nexin 6 3.17005
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 3.17
AXIN1 axin 1 3.15955
ANKRD12 ankyrin repeat domain 12 3.1418
LOC128125814 uncharacterized LOC128125814 3.13695
MAP7D1 MAP7 domain containing 1 3.12995
PCDHGA5 protocadherin gamma subfamily A, 5 3.12925
PLK3 polo-like kinase 3 3.11875
ZNF410 zinc finger protein 410 3.11345
TICAM1 toll-like receptor adaptor molecule 1 3.09985
ARHGAP12 Rho GTPase activating protein 12 3.0936
CYCS cytochrome c, somatic 3.0898
GDI1 GDP dissociation inhibitor 1 3.0886
NOP2 NOP2 nucleolar protein 3.0717
IER2 immediate early response 2 3.0515
SRC SRC proto-oncogene, non-receptor tyrosine kinase 3.0368
RAB9A RAB9A, member RAS oncogene family 3.03375
CDK17 cyclin-dependent kinase 17 3.031
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 3.03023
TSC22D3 TSC22 domain family, member 3 3.0173
KPNA4 karyopherin alpha 4 (importin alpha 3) 3.00952
MAP3K4 mitogen-activated protein kinase kinase kinase 4 2.9883
ISG20 interferon stimulated exonuclease gene 20kDa 2.98082
EGFR epidermal growth factor receptor 2.97762
SYNJ2 synaptojanin 2 2.9696
MOSPD1 motile sperm domain containing 1 2.96935
EED embryonic ectoderm development 2.9674
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.94695
TNIP1 TNFAIP3 interacting protein 1 2.9412
VEZT vezatin, adherens junctions transmembrane protein 2.9265
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 2.9086
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 2.9005
WASHC4 WASH complex subunit 4 2.8909
KDM6B lysine (K)-specific demethylase 6B 2.88982
KCMF1 potassium channel modulatory factor 1 2.88055
SOCS2 suppressor of cytokine signaling 2 2.87995
HOMER2 homer scaffolding protein 2 2.87747
H2BC21 H2B clustered histone 21 2.87485
MARCHF5 membrane associated ring-CH-type finger 5 2.8713
ZSCAN9 zinc finger and SCAN domain containing 9 2.8568
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 2.85655
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 2.85395
CLIP2 CAP-GLY domain containing linker protein 2 2.8527
KDM5A lysine (K)-specific demethylase 5A 2.84875
PLSCR3 phospholipid scramblase 3 2.838
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 2.83518
TNIP2 TNFAIP3 interacting protein 2 2.8337
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.82185
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.8198
TGFB1I1 transforming growth factor beta 1 induced transcript 1 2.8145
AGO2 argonaute RISC catalytic component 2 2.81015
ZZZ3 zinc finger, ZZ-type containing 3 2.80775
SYT1 synaptotagmin I 2.80465
MSN moesin 2.8043
MBNL1 muscleblind-like splicing regulator 1 2.79205
UBR4 ubiquitin protein ligase E3 component n-recognin 4 2.79193
ZYX zyxin 2.78958
MGLL monoglyceride lipase 2.78915
GADD45A growth arrest and DNA-damage-inducible, alpha 2.7872
SECISBP2L SECIS binding protein 2-like 2.78302
FPGS folylpolyglutamate synthase 2.77845
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.7761
EPN2 epsin 2 2.77275
MAEA macrophage erythroblast attacher 2.76975
FOS FBJ murine osteosarcoma viral oncogene homolog 2.7678
TRIM13 tripartite motif containing 13 2.7669
NMU neuromedin U 2.74685
JADE2 jade family PHD finger 2 2.74197
UBXN7 UBX domain protein 7 2.73115
ST18 suppression of tumorigenicity 18, zinc finger 2.7295
LIF leukemia inhibitory factor 2.72505
COL17A1 collagen, type XVII, alpha 1 2.7226
EIF3D eukaryotic translation initiation factor 3, subunit D 2.7213
PPP1R15A protein phosphatase 1, regulatory subunit 15A 2.72078
OLA1 Obg-like ATPase 1 2.70935
HDAC7 histone deacetylase 7 2.70525
PARP8 poly (ADP-ribose) polymerase family, member 8 2.7019
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.69795
NARS1 asparaginyl-tRNA synthetase 1 2.69205
TRAPPC14 trafficking protein particle complex subunit 14 2.68875
PRKCQ protein kinase C, theta 2.68222
FASTKD5 FAST kinase domains 5 2.67885
YY1AP1 YY1 associated protein 1 2.6777
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.67185
HMGA1 high mobility group AT-hook 1 2.67077
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 2.6631
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.65865
CHD1 chromodomain helicase DNA binding protein 1 2.65705
MYLK myosin light chain kinase 2.65625
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.6536
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.6432
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 2.64245
IL37 interleukin 37 2.6352
PALM2AKAP2 PALM2 and AKAP2 fusion 2.63405
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like 2.627
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.6231
ARL8B ADP-ribosylation factor-like 8B 2.6166
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 2.59255
IGF2R insulin-like growth factor 2 receptor 2.59095
CLIP1 CAP-GLY domain containing linker protein 1 2.5853
GABPB1 GA binding protein transcription factor, beta subunit 1 2.56715
CDC34 cell division cycle 34 2.5633
DNM1L dynamin 1-like 2.56195
GLRX glutaredoxin (thioltransferase) 2.56047
ADGRG1 adhesion G protein-coupled receptor G1 2.55918
NT5E 5'-nucleotidase, ecto (CD73) 2.54705
TPD52L2 tumor protein D52-like 2 2.54585
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 2.5439
RHOF ras homolog family member F (in filopodia) 2.5366
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 2.5361
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.53185
ZNF586 zinc finger protein 586 2.5305
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.528
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 2.5192
CARS1 cysteinyl-tRNA synthetase 1 2.51842
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.51735
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2.51375
CA6 carbonic anhydrase VI 2.5109
TET3 tet methylcytosine dioxygenase 3 2.5048
FAM193A family with sequence similarity 193, member A 2.5037
TSC22D4 TSC22 domain family, member 4 2.50305
PRSS8 protease, serine, 8 2.5019
KRT7 keratin 7, type II 2.50165
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 2.5009
MOG myelin oligodendrocyte glycoprotein 2.49903
ATG2B autophagy related 2B 2.4967
SERINC1 serine incorporator 1 2.4959
ITGB5 integrin, beta 5 2.49365
ITCH itchy E3 ubiquitin protein ligase 2.49227
CAMTA2 calmodulin binding transcription activator 2 2.49195
AK5 adenylate kinase 5 2.48395
RHOG ras homolog family member G 2.4801
KDM5C lysine (K)-specific demethylase 5C 2.4733
OPTN optineurin 2.46913
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 2.4643
IARS1 isoleucyl-tRNA synthetase 1 2.4564
SLC35E2B solute carrier family 35, member E2B 2.45335
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 2.45265
JMJD1C jumonji domain containing 1C 2.45155
MAPK6 mitogen-activated protein kinase 6 2.44725
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 2.44065
RRAGC Ras-related GTP binding C 2.4379
CTPS1 CTP synthase 1 2.43355
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 2.4262
ANXA11 annexin A11 2.41778
BASP1 brain abundant, membrane attached signal protein 1 2.4152
PCDH1 protocadherin 1 2.41503
BANP BTG3 associated nuclear protein 2.4105
ZNF292 zinc finger protein 292 2.41005
ASNS asparagine synthetase (glutamine-hydrolyzing) 2.40425
AXL AXL receptor tyrosine kinase 2.39612
LAMC2 laminin, gamma 2 2.39572
NRBF2 nuclear receptor binding factor 2 2.3782
MMP1 matrix metallopeptidase 1 2.36893
INTS6 integrator complex subunit 6 2.3683
KLHL24 kelch-like family member 24 2.36815
C2CD2 C2 calcium-dependent domain containing 2 2.364
BAZ1A bromodomain adjacent to zinc finger domain, 1A 2.35838
HBS1L HBS1-like translational GTPase 2.35288
GOLT1A golgi transport 1A 2.351
UBA1 ubiquitin-like modifier activating enzyme 1 2.35005
RTN4 reticulon 4 2.346
PABPC3 poly(A) binding protein, cytoplasmic 3 2.3457
DIRAS2 DIRAS family, GTP-binding RAS-like 2 2.3429
STYXL1 serine/threonine/tyrosine interacting-like 1 2.34105
CLOCK clock circadian regulator 2.33965
PHC2 polyhomeotic homolog 2 (Drosophila) 2.338
MYO1D myosin ID 2.33535
TBC1D15 TBC1 domain family, member 15 2.3346
PRSS3 protease, serine, 3 2.33247
SUN2 Sad1 and UNC84 domain containing 2 2.33095
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 2.32915
KRT81 keratin 81, type II 2.32875
AADAC arylacetamide deacetylase 2.3266
NCOA3 nuclear receptor coactivator 3 2.32487
AHNAK2 AHNAK nucleoprotein 2 2.3192
DUSP6 dual specificity phosphatase 6 2.3166
UBE2H ubiquitin-conjugating enzyme E2H 2.31652
ABLIM3 actin binding LIM protein family, member 3 2.30905
ZNF574 zinc finger protein 574 2.3085
SPAG9 sperm associated antigen 9 2.30753
FOXJ3 forkhead box J3 2.3063
MKNK2 MAP kinase interacting serine/threonine kinase 2 2.306
DUSP8 dual specificity phosphatase 8 2.3039
MRPS10 mitochondrial ribosomal protein S10 2.2972
GREM1 gremlin 1, DAN family BMP antagonist 2.29682
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 2.29655
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 2.29448
BCAR3 breast cancer anti-estrogen resistance 3 2.2906
TUBA4A tubulin, alpha 4a 2.2891
CAB39L calcium binding protein 39-like 2.2885
FABP2 fatty acid binding protein 2, intestinal 2.2858
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.28397
WAC WW domain containing adaptor with coiled-coil 2.28323
MACO1 macoilin 1 2.2802
LSG1 large 60S subunit nuclear export GTPase 1 2.28008
FRYL FRY-like 2.2743
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 2.27065
DCP1A decapping mRNA 1A 2.26945
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 2.2665
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2.26615
EPHA3 EPH receptor A3 2.2639
ADGRE5 adhesion G protein-coupled receptor E5 2.263
DOHH deoxyhypusine hydroxylase/monooxygenase 2.26175
DNASE2B deoxyribonuclease II beta 2.2566
CARD10 caspase recruitment domain family, member 10 2.25292
MBTD1 mbt domain containing 1 2.24575
CCDC68 coiled-coil domain containing 68 2.2456
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 2.24457
BPHL biphenyl hydrolase-like (serine hydrolase) 2.24065
TMEM184B transmembrane protein 184B 2.2393
KCNK7 potassium channel, two pore domain subfamily K, member 7 2.2379
COQ10B coenzyme Q10 homolog B (S. cerevisiae) 2.23785
WIPF1 WAS/WASL interacting protein family, member 1 2.23632
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 2.23092
IMP4 IMP4, U3 small nucleolar ribonucleoprotein 2.2271
RGCC regulator of cell cycle 2.2257
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 2.2232
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 2.21715
FILIP1L filamin A interacting protein 1-like 2.21695
F2RL1 coagulation factor II (thrombin) receptor-like 1 2.21653
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 2.21615
KLK6 kallikrein-related peptidase 6 2.21567
CCNT1 cyclin T1 2.2146
FLNB filamin B, beta 2.21318
SMNDC1 survival motor neuron domain containing 1 2.2117
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.20918
RIOK3 RIO kinase 3 2.2066
TJAP1 tight junction associated protein 1 (peripheral) 2.20528
PSORS1C2 psoriasis susceptibility 1 candidate 2 2.2005
ITGA6 integrin, alpha 6 2.19725
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 2.1966
F2R coagulation factor II (thrombin) receptor 2.1953
BAZ2B bromodomain adjacent to zinc finger domain, 2B 2.1948
ZNF281 zinc finger protein 281 2.1902
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 2.1902
TMEM144 transmembrane protein 144 2.1862
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 2.17893
CLCF1 cardiotrophin-like cytokine factor 1 2.17555
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.17505
IST1 increased sodium tolerance 1 homolog (yeast) 2.1718
POGK pogo transposable element with KRAB domain 2.16985
ASCC1 activating signal cointegrator 1 complex subunit 1 2.16935
EHD1 EH-domain containing 1 2.16918
CLK3 CDC-like kinase 3 2.16895
RNF24 ring finger protein 24 2.16745
CFLAR CASP8 and FADD-like apoptosis regulator 2.16596
PELI1 pellino E3 ubiquitin protein ligase 1 2.16455
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 2.16325
EVA1B eva-1 homolog B (C. elegans) 2.16057
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 2.15575
RAB33A RAB33A, member RAS oncogene family 2.15265
ATF3 activating transcription factor 3 2.1512
PDZD8 PDZ domain containing 8 2.14825
EIF4H eukaryotic translation initiation factor 4H 2.14755
NR4A2 nuclear receptor subfamily 4, group A, member 2 2.14602
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.14547
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.14515
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 2.14425
TUG1 taurine up-regulated 1 (non-protein coding) 2.14355
NCK2 NCK adaptor protein 2 2.14275
KLF7 Kruppel-like factor 7 (ubiquitous) 2.14215
GABARAPL1 GABA(A) receptor-associated protein like 1 2.13925
AUP1 ancient ubiquitous protein 1 2.13695
PHF1 PHD finger protein 1 2.13622
MYO6 myosin VI 2.13593
EIF6 eukaryotic translation initiation factor 6 2.13395
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 2.13375
SMTN smoothelin 2.1313
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.1231
CLTB clathrin, light chain B 2.12111
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 2.1211
EEIG1 estrogen-induced osteoclastogenesis regulator 1 2.1201
PCGF3 polycomb group ring finger 3 2.11928
COTL1 coactosin-like F-actin binding protein 1 2.118
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 2.11725
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 2.11438
IRX4 iroquois homeobox 4 2.1136
CCSER2 coiled-coil serine-rich protein 2 2.11267
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.109
DHRS9 dehydrogenase/reductase (SDR family) member 9 2.10815
BECN1 beclin 1, autophagy related 2.10755
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 2.1074
GPBP1L1 GC-rich promoter binding protein 1-like 1 2.1054
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 2.1033
EFS embryonal Fyn-associated substrate 2.10297
PTK2 protein tyrosine kinase 2 2.1012
PARP6 poly (ADP-ribose) polymerase family, member 6 2.0957
RAP1GAP RAP1 GTPase activating protein 2.09235
RAB3B RAB3B, member RAS oncogene family 2.09232
RAB8B RAB8B, member RAS oncogene family 2.0906
CLDN4 claudin 4 2.0888
KRT23 keratin 23, type I 2.08675
BICRAL BICRA like chromatin remodeling complex associated protein 2.08645
ASL argininosuccinate lyase 2.086
LRRC8E leucine rich repeat containing 8 family, member E 2.0856
PCBP1 poly(rC) binding protein 1 2.0827
PRTN3 proteinase 3 2.0825
FAM168B family with sequence similarity 168, member B 2.08145
C2CD2L C2CD2-like 2.0814
MTCH1 mitochondrial carrier 1 2.08105
IL7R interleukin 7 receptor 2.0803
NAP1L2 nucleosome assembly protein 1-like 2 2.08025
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 2.0754
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 2.07435
PERP PERP, TP53 apoptosis effector 2.0724
TAS2R10 taste receptor, type 2, member 10 2.07135
AOC1 amine oxidase, copper containing 1 2.0687
TM4SF20 transmembrane 4 L six family member 20 2.06805
PHOSPHO2-KLHL23 PHOSPHO2-KLHL23 readthrough 2.0658
MISP mitotic spindle positioning 2.06135
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 2.061
MNAT1 MNAT CDK-activating kinase assembly factor 1 2.05975
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome 2.0595
MEF2D myocyte enhancer factor 2D 2.0569
SPX spexin hormone 2.0551
CPLX3 complexin 3 2.05095
TRIM8 tripartite motif containing 8 2.0475
WDR13 WD repeat domain 13 2.04545
PCNP PEST proteolytic signal containing nuclear protein 2.04365
PHF20L1 PHD finger protein 20-like 1 2.04025
TRIP4 thyroid hormone receptor interactor 4 2.04025
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 2.0391
CGGBP1 CGG triplet repeat binding protein 1 2.03875
PAIP2B poly(A) binding protein interacting protein 2B 2.03695
CSRP1 cysteine and glycine-rich protein 1 2.03652
TTLL7 tubulin tyrosine ligase-like family member 7 2.03595
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) 2.0355
CD72 CD72 molecule 2.03425
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 2.03325
LCE2B late cornified envelope 2B 2.0331
PTPRK protein tyrosine phosphatase, receptor type, K 2.03265
ALDOB aldolase B, fructose-bisphosphate 2.03198
PTX3 pentraxin 3, long 2.0319
NIBAN1 niban apoptosis regulator 1 2.0318
ZNF451 zinc finger protein 451 2.02955
NR1D2 nuclear receptor subfamily 1, group D, member 2 2.02925
AQP3 aquaporin 3 (Gill blood group) 2.029
NCK1 NCK adaptor protein 1 2.02835
YME1L1 YME1-like 1 ATPase 2.02788
THSD7A thrombospondin, type I, domain containing 7A 2.02728
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 2.02295
TARS1 threonyl-tRNA synthetase 1 2.02285
ZBTB35 zinc finger and BTB domain containing 35 2.02262
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 2.02235
GPR87 G protein-coupled receptor 87 2.02075
ITPRID2 ITPR interacting domain containing 2 2.02015
NOP14 NOP14 nucleolar protein 2.01835
MAN2A1 mannosidase, alpha, class 2A, member 1 2.01805
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 2.01132
DACH1 dachshund family transcription factor 1 2.01105
CSNK1G3 casein kinase 1, gamma 3 2.01035
ZKSCAN2 zinc finger with KRAB and SCAN domains 2 2.0075
LIAS lipoic acid synthetase 2.0023
PIBF1 progesterone immunomodulatory binding factor 1 2.001

decreased expression

Symbol Name Standardized Value
TCTN1 tectonic family member 1 -10.0
B4GAT1 beta-1,4-glucuronyltransferase 1 -10.0
CD320 CD320 molecule -9.7374
ICAM3 intercellular adhesion molecule 3 -9.27995
FGFR4 fibroblast growth factor receptor 4 -8.88297
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -8.4885
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -8.4264
PGM1 phosphoglucomutase 1 -8.3719
ALDOC aldolase C, fructose-bisphosphate -7.9865
PGAM4 phosphoglycerate mutase family member 4 -7.58775
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -7.41097
ISOC1 isochorismatase domain containing 1 -7.3926
COG7 component of oligomeric golgi complex 7 -7.31885
ZW10 zw10 kinetochore protein -7.2997
CCNA2 cyclin A2 -7.29345
AURKB aurora kinase B -7.28745
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -7.28375
PSRC1 proline/serine-rich coiled-coil 1 -7.2768
TMEM109 transmembrane protein 109 -7.0299
CDC20 cell division cycle 20 -6.98695
NT5DC2 5'-nucleotidase domain containing 2 -6.95335
MLEC malectin -6.635
PARP1 poly (ADP-ribose) polymerase 1 -6.62515
PLK1 polo-like kinase 1 -6.4618
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -6.4508
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -6.3087
MELK maternal embryonic leucine zipper kinase -6.29565
TARBP1 TAR (HIV-1) RNA binding protein 1 -6.2812
STMN1 stathmin 1 -6.2427
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -5.95185
BIRC5 baculoviral IAP repeat containing 5 -5.9508
PCNA proliferating cell nuclear antigen -5.92795
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -5.86485
TMEM97 transmembrane protein 97 -5.84439
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -5.757
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -5.68095
CDK1 cyclin-dependent kinase 1 -5.65388
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -5.6247
NLRP2B NLR family pyrin domain containing 2B -5.56765
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -5.49153
MYCBP MYC binding protein -5.45308
ADI1 acireductone dioxygenase 1 -5.43315
CCNB1 cyclin B1 -5.292
NFIL3 nuclear factor, interleukin 3 regulated -5.2872
LDHD lactate dehydrogenase D -5.26395
BLCAP bladder cancer associated protein -5.25685
RPA3 replication protein A3, 14kDa -5.2357
HMGA2 high mobility group AT-hook 2 -5.21305
MRPL12 mitochondrial ribosomal protein L12 -5.15165
DERA deoxyribose-phosphate aldolase (putative) -5.1285
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -5.10485
POLR1A polymerase (RNA) I polypeptide A, 194kDa -5.08978
NUP85 nucleoporin 85kDa -5.0648
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -5.01385
HAT1 histone acetyltransferase 1 -5.01065
RPS4Y1 ribosomal protein S4, Y-linked 1 -5.0
TSEN2 TSEN2 tRNA splicing endonuclease subunit -4.97905
THAP11 THAP domain containing 11 -4.95045
TOP2A topoisomerase (DNA) II alpha 170kDa -4.90587
ASF1B anti-silencing function 1B histone chaperone -4.8743
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -4.78035
PAGR1 PAXIP1 associated glutamate-rich protein 1 -4.76765
TEDC2 tubulin epsilon and delta complex 2 -4.7562
GTF2A2 general transcription factor IIA, 2, 12kDa -4.74225
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -4.725
UBE2C ubiquitin-conjugating enzyme E2C -4.63895
AMDHD2 amidohydrolase domain containing 2 -4.57835
MCM10 minichromosome maintenance complex component 10 -4.55665
ECH1 enoyl CoA hydratase 1, peroxisomal -4.54675
PCCB propionyl CoA carboxylase, beta polypeptide -4.5292
PPIC peptidylprolyl isomerase C (cyclophilin C) -4.51647
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -4.51085
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -4.4726
HSPA1A heat shock 70kDa protein 1A -4.4566
CD58 CD58 molecule -4.45045
NISCH nischarin -4.38125
TRIP13 thyroid hormone receptor interactor 13 -4.3532
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -4.34902
CHMP6 charged multivesicular body protein 6 -4.3282
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -4.3205
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -4.3084
PROS1 protein S (alpha) -4.287
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -4.21945
CHEK2 checkpoint kinase 2 -4.2081
SOAT2 sterol O-acyltransferase 2 -4.1994
TRAP1 TNF receptor-associated protein 1 -4.1891
NIPSNAP1 nipsnap homolog 1 (C. elegans) -4.17478
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -4.1522
CDC45 cell division cycle 45 -4.12315
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -4.1016
HSPB1 heat shock 27kDa protein 1 -4.10145
SCGB1D1 secretoglobin, family 1D, member 1 -4.08595
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -4.07135
MIS18A MIS18 kinetochore protein A -4.0691
CENPM centromere protein M -4.06455
STIMATE STIM activating enhancer -4.04725
TSPAN6 tetraspanin 6 -4.03155
HADH hydroxyacyl-CoA dehydrogenase -4.01757
KIF15 kinesin family member 15 -3.98865
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -3.9534
GINS3 GINS complex subunit 3 (Psf3 homolog) -3.9275
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -3.9251
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -3.9138
KIF11 kinesin family member 11 -3.90715
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -3.9055
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -3.88315
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -3.8819
SDF2L1 stromal cell-derived factor 2-like 1 -3.8562
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -3.85195
GINS2 GINS complex subunit 2 (Psf2 homolog) -3.8472
NUCB2 nucleobindin 2 -3.84025
DDB2 damage-specific DNA binding protein 2, 48kDa -3.83955
TK1 thymidine kinase 1, soluble -3.8102
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -3.79775
PYCR3 pyrroline-5-carboxylate reductase 3 -3.77545
PARN poly(A)-specific ribonuclease -3.7325
DSCC1 DNA replication and sister chromatid cohesion 1 -3.7143
BCL7C B-cell CLL/lymphoma 7C -3.7137
SCAND1 SCAN domain containing 1 -3.6881
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -3.6725
FEN1 flap structure-specific endonuclease 1 -3.66863
ZNF274 zinc finger protein 274 -3.65385
PRCP prolylcarboxypeptidase (angiotensinase C) -3.64955
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.6389
DHFR dihydrofolate reductase -3.61046
CENPX centromere protein X -3.5777
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -3.57755
GMNN geminin, DNA replication inhibitor -3.56492
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -3.5632
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 -3.5288
PRR7 proline rich 7 (synaptic) -3.52385
LAGE3 L antigen family, member 3 -3.50285
LMNB1 lamin B1 -3.48715
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -3.47685
DEXI Dexi homolog (mouse) -3.46265
GAMT guanidinoacetate N-methyltransferase -3.4616
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -3.45665
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -3.45332
ERCC6L excision repair cross-complementation group 6-like -3.44535
MSH6 mutS homolog 6 -3.42963
TFDP1 transcription factor Dp-1 -3.4182
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -3.3899
ALG6 ALG6, alpha-1,3-glucosyltransferase -3.3813
RABL6 RAB, member RAS oncogene family-like 6 -3.37995
FANCG Fanconi anemia, complementation group G -3.3793
MRPL17 mitochondrial ribosomal protein L17 -3.3642
CETN3 centrin, EF-hand protein, 3 -3.33985
MSMO1 methylsterol monooxygenase 1 -3.32465
TBC1D10C TBC1 domain family, member 10C -3.3034
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -3.30225
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -3.29303
GINS1 GINS complex subunit 1 (Psf1 homolog) -3.29035
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 -3.2889
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -3.2797
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.26603
SHCBP1 SHC SH2-domain binding protein 1 -3.24525
RPIA ribose 5-phosphate isomerase A -3.20115
PALB2 partner and localizer of BRCA2 -3.1829
TCTN3 tectonic family member 3 -3.17423
ERBB2 erb-b2 receptor tyrosine kinase 2 -3.17375
THAP7 THAP domain containing 7 -3.173
ARFIP2 ADP-ribosylation factor interacting protein 2 -3.16125
CARHSP1 calcium regulated heat stable protein 1, 24kDa -3.1589
INCENP inner centromere protein antigens 135/155kDa -3.1238
GALK1 galactokinase 1 -3.11825
SORD sorbitol dehydrogenase -3.10825
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -3.0986
WDR77 WD repeat domain 77 -3.08597
FN3KRP fructosamine 3 kinase related protein -3.07825
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -3.0748
PGRMC1 progesterone receptor membrane component 1 -3.07135
MCM3 minichromosome maintenance complex component 3 -3.06685
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -3.05922
HMGN3 high mobility group nucleosomal binding domain 3 -3.0586
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 -3.0571
TMEM14A transmembrane protein 14A -3.0506
VRK1 vaccinia related kinase 1 -3.0484
UNC119B unc-119 homolog B (C. elegans) -3.04695
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -3.0442
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.0412
GLT8D1 glycosyltransferase 8 domain containing 1 -3.03813
NME3 NME/NM23 nucleoside diphosphate kinase 3 -3.02945
KLHDC2 kelch domain containing 2 -3.02875
KANSL1 KAT8 regulatory NSL complex subunit 1 -3.0197
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -3.0179
WRAP53 WD repeat containing, antisense to TP53 -3.01447
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -3.0056
BCKDK branched chain ketoacid dehydrogenase kinase -2.99995
HMG20B high mobility group 20B -2.99705
NCAPG2 non-SMC condensin II complex, subunit G2 -2.9901
UBE3C ubiquitin protein ligase E3C -2.9859
COA3 cytochrome c oxidase assembly factor 3 -2.9726
QTRT1 queuine tRNA-ribosyltransferase 1 -2.97065
BBS1 Bardet-Biedl syndrome 1 -2.9616
CHAD chondroadherin -2.9593
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.95515
ARHGAP19 Rho GTPase activating protein 19 -2.9546
CKS1B CDC28 protein kinase regulatory subunit 1B -2.9511
RAD51AP1 RAD51 associated protein 1 -2.94375
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 -2.939
CETN2 centrin, EF-hand protein, 2 -2.9351
CCDC106 coiled-coil domain containing 106 -2.9325
PARG poly (ADP-ribose) glycohydrolase -2.9317
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle -2.92405
VAV3 vav 3 guanine nucleotide exchange factor -2.92175
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -2.91555
KIF22 kinesin family member 22 -2.91097
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.9064
SPDEF SAM pointed domain containing ETS transcription factor -2.90525
MRTFB myocardin related transcription factor B -2.902
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.90085
KIFC1 kinesin family member C1 -2.8917
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa -2.8906
CLN3 ceroid-lipofuscinosis, neuronal 3 -2.89055
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -2.8835
CFAP20 cilia and flagella associated protein 20 -2.87995
XYLT2 xylosyltransferase II -2.87675
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -2.87155
UBL5 ubiquitin-like 5 -2.87015
RMI1 RecQ mediated genome instability 1 -2.86985
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.85332
AMT aminomethyltransferase -2.84845
PRUNE1 prune exopolyphosphatase 1 -2.84532
DCTPP1 dCTP pyrophosphatase 1 -2.8429
RBM15B RNA binding motif protein 15B -2.83935
EMC9 ER membrane protein complex subunit 9 -2.83795
NENF neudesin neurotrophic factor -2.8378
SAMM50 SAMM50 sorting and assembly machinery component -2.83775
IFI30 interferon, gamma-inducible protein 30 -2.8374
VKORC1 vitamin K epoxide reductase complex, subunit 1 -2.83575
LIME1 Lck interacting transmembrane adaptor 1 -2.83485
CASP7 caspase 7, apoptosis-related cysteine peptidase -2.83165
DPH2 DPH2 homolog (S. cerevisiae) -2.80825
AAMP angio-associated, migratory cell protein -2.80455
MRPL19 mitochondrial ribosomal protein L19 -2.8045
ISOC2 isochorismatase domain containing 2 -2.8026
MRPL11 mitochondrial ribosomal protein L11 -2.7996
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.79745
RAD54L RAD54-like (S. cerevisiae) -2.79675
DHCR7 7-dehydrocholesterol reductase -2.79165
MCMBP minichromosome maintenance complex binding protein -2.79085
DUT deoxyuridine triphosphatase -2.78048
NUP107 nucleoporin 107kDa -2.77815
FZD7 frizzled class receptor 7 -2.76832
HIRIP3 HIRA interacting protein 3 -2.76345
ACAA1 acetyl-CoA acyltransferase 1 -2.76155
CDC6 cell division cycle 6 -2.75675
ZDHHC24 zinc finger, DHHC-type containing 24 -2.7553
INTS3 integrator complex subunit 3 -2.73775
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.7352
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.7321
REEP5 receptor accessory protein 5 -2.73073
SH3D19 SH3 domain containing 19 -2.72958
DYNLT3 dynein, light chain, Tctex-type 3 -2.7266
SNRPE small nuclear ribonucleoprotein polypeptide E -2.726
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 -2.7239
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -2.7214
PDIA4 protein disulfide isomerase family A, member 4 -2.7061
OCEL1 occludin/ELL domain containing 1 -2.7049
C5 complement component 5 -2.70185
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.70073
MYF6 myogenic factor 6 (herculin) -2.69675
RHOA ras homolog family member A -2.68917
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.68655
RFC3 replication factor C (activator 1) 3, 38kDa -2.68628
FZD4 frizzled class receptor 4 -2.6844
OIP5 Opa interacting protein 5 -2.6821
KHK ketohexokinase (fructokinase) -2.67893
SKIC8 SKI8 subunit of superkiller complex -2.67587
CENPS-CORT CENPS-CORT readthrough -2.67175
SYBU syntabulin (syntaxin-interacting) -2.6711
NEK4 NIMA-related kinase 4 -2.6594
ABHD14A abhydrolase domain containing 14A -2.6584
GATA4 GATA binding protein 4 -2.6555
THOP1 thimet oligopeptidase 1 -2.65355
LBR lamin B receptor -2.64865
TMX1 thioredoxin-related transmembrane protein 1 -2.64647
TNNC2 troponin C type 2 (fast) -2.6375
NCAPH non-SMC condensin I complex, subunit H -2.6372
SMCO4 single-pass membrane protein with coiled-coil domains 4 -2.6307
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.62845
TNNI2 troponin I type 2 (skeletal, fast) -2.6268
SESN1 sestrin 1 -2.6254
CDCA3 cell division cycle associated 3 -2.625
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.62345
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) -2.62173
TIMELESS timeless circadian clock -2.62127
MYBPH myosin binding protein H -2.6209
MRPL16 mitochondrial ribosomal protein L16 -2.61405
EXO1 exonuclease 1 -2.6088
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -2.60675
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa -2.60645
TARBP2 TAR (HIV-1) RNA binding protein 2 -2.60615
MYL1 myosin, light chain 1, alkali; skeletal, fast -2.6031
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2 -2.60115
PDIA6 protein disulfide isomerase family A, member 6 -2.60016
UXT ubiquitously-expressed, prefoldin-like chaperone -2.59024
CASQ2 calsequestrin 2 (cardiac muscle) -2.5901
TSEN34 TSEN34 tRNA splicing endonuclease subunit -2.58915
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.58615
HMGN2 high mobility group nucleosomal binding domain 2 -2.58385
ZNF83 zinc finger protein 83 -2.57955
TTC38 tetratricopeptide repeat domain 38 -2.5614
PTTG1 pituitary tumor-transforming 1 -2.56085
DCLRE1B DNA cross-link repair 1B -2.55555
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 -2.55409
TRAIP TRAF interacting protein -2.5523
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase -2.54905
CA5A carbonic anhydrase VA, mitochondrial -2.54815
PIMREG PICALM interacting mitotic regulator -2.5335
ZWINT ZW10 interacting kinetochore protein -2.53095
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -2.5292
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 -2.5291
TYROBP TYRO protein tyrosine kinase binding protein -2.5289
CGREF1 cell growth regulator with EF-hand domain 1 -2.5202
HOXA5 homeobox A5 -2.51035
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.50985
MSH2 mutS homolog 2 -2.5094
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa -2.50705
MYO19 myosin XIX -2.50685
DGCR6L DiGeorge syndrome critical region gene 6-like -2.50525
TMEM106C transmembrane protein 106C -2.50315
CCS copper chaperone for superoxide dismutase -2.4931
NHP2 NHP2 ribonucleoprotein -2.49125
MRPS7 mitochondrial ribosomal protein S7 -2.491
CCDC47 coiled-coil domain containing 47 -2.48985
CALML4 calmodulin-like 4 -2.48872
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa -2.48787
RPL26L1 ribosomal protein L26-like 1 -2.48565
PDZD2 PDZ domain containing 2 -2.48095
ZNF200 zinc finger protein 200 -2.478
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) -2.4724
ERI2 ERI1 exoribonuclease family member 2 -2.46625
CBR1 carbonyl reductase 1 -2.466
WDR3 WD repeat domain 3 -2.4659
PECR peroxisomal trans-2-enoyl-CoA reductase -2.46195
ICMT isoprenylcysteine carboxyl methyltransferase -2.46068
FTSJ3 FtsJ homolog 3 (E. coli) -2.4566
KIF14 kinesin family member 14 -2.4557
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) -2.4544
NAGA N-acetylgalactosaminidase, alpha- -2.45415
TNNI1 troponin I type 1 (skeletal, slow) -2.4454
CCNE1 cyclin E1 -2.44215
HNRNPCL1 heterogeneous nuclear ribonucleoprotein C-like 1 -2.4421
GYG2 glycogenin 2 -2.43583
CEP131 centrosomal protein 131kDa -2.43285
FDXR ferredoxin reductase -2.4289
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) -2.4287
DHCR24 24-dehydrocholesterol reductase -2.4242
MRNIP MRN complex interacting protein -2.41085
CRLF1 cytokine receptor-like factor 1 -2.40495
POLK polymerase (DNA directed) kappa -2.3992
CHST10 carbohydrate sulfotransferase 10 -2.39725
G6PC3 glucose 6 phosphatase, catalytic, 3 -2.39542
RCL1 RNA terminal phosphate cyclase-like 1 -2.3893
FKBP3 FK506 binding protein 3, 25kDa -2.38875
CDT1 chromatin licensing and DNA replication factor 1 -2.3887
NUP93 nucleoporin 93kDa -2.38245
C2CD5 C2 calcium-dependent domain containing 5 -2.38005
SLC2A4RG SLC2A4 regulator -2.37865
CRELD2 cysteine-rich with EGF-like domains 2 -2.3786
SMPX small muscle protein, X-linked -2.3773
ZMYM3 zinc finger, MYM-type 3 -2.36935
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.36835
CNPY2 canopy FGF signaling regulator 2 -2.36658
ELP5 elongator acetyltransferase complex subunit 5 -2.3649
IL11RA interleukin 11 receptor, alpha -2.36225
RFC5 replication factor C (activator 1) 5, 36.5kDa -2.36082
TM7SF3 transmembrane 7 superfamily member 3 -2.35835
PPP1R7 protein phosphatase 1, regulatory subunit 7 -2.35635
POLR1G RNA polymerase I subunit G -2.3533
TSNAXIP1 translin-associated factor X interacting protein 1 -2.353
MXD3 MAX dimerization protein 3 -2.3524
GAA glucosidase, alpha; acid -2.3508
SPIN2B spindlin family, member 2B -2.3483
S100A9 S100 calcium binding protein A9 -2.34702
MYL11 myosin light chain 11 -2.34455
COG4 component of oligomeric golgi complex 4 -2.34085
KCTD12 potassium channel tetramerization domain containing 12 -2.33888
RRAGB Ras-related GTP binding B -2.33835
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.33695
CRELD1 cysteine-rich with EGF-like domains 1 -2.33665
DENND2D DENN/MADD domain containing 2D -2.333
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.33032
AVPR1B arginine vasopressin receptor 1B -2.32815
UNG uracil-DNA glycosylase -2.32555
CFI complement factor I -2.32205
NELFCD negative elongation factor complex member C/D -2.31985
PSPN persephin -2.31365
DCK deoxycytidine kinase -2.3127
ATP5MF ATP synthase membrane subunit f -2.31255
KAT8 K(lysine) acetyltransferase 8 -2.3031
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.30253
PXMP2 peroxisomal membrane protein 2, 22kDa -2.30083
LMF2 lipase maturation factor 2 -2.30075
SIRT3 sirtuin 3 -2.297
MYL2 myosin, light chain 2, regulatory, cardiac, slow -2.2939
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -2.29385
MAGEH1 melanoma antigen family H1 -2.29095
PYCARD PYD and CARD domain containing -2.28895
TMCO1 transmembrane and coiled-coil domains 1 -2.2874
HAUS7 HAUS augmin-like complex, subunit 7 -2.2867
TMED1 transmembrane emp24 protein transport domain containing 1 -2.28595
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -2.28585
SLC66A3 solute carrier family 66 member 3 -2.28585
LRRC61 leucine rich repeat containing 61 -2.28385
SMG6 SMG6 nonsense mediated mRNA decay factor -2.2819
CCNH cyclin H -2.2802
CDK2 cyclin-dependent kinase 2 -2.279
FANCC Fanconi anemia, complementation group C -2.27715
TCTA T-cell leukemia translocation altered -2.27665
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -2.27575
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -2.26965
ATP5MC1 ATP synthase membrane subunit c locus 1 -2.2607
RUVBL1 RuvB-like AAA ATPase 1 -2.259
CDK4 cyclin-dependent kinase 4 -2.25735
TUSC3 tumor suppressor candidate 3 -2.25695
NASP nuclear autoantigenic sperm protein (histone-binding) -2.2566
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -2.25395
TNNT3 troponin T type 3 (skeletal, fast) -2.25065
MAGED1 melanoma antigen family D1 -2.24895
TRMT5 tRNA methyltransferase 5 -2.24785
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 -2.2468
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -2.24645
ACOX2 acyl-CoA oxidase 2, branched chain -2.2463
RNF40 ring finger protein 40, E3 ubiquitin protein ligase -2.2448
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -2.24465
PLK4 polo-like kinase 4 -2.24405
S100A4 S100 calcium binding protein A4 -2.24075
SPHK2 sphingosine kinase 2 -2.2398
NME4 NME/NM23 nucleoside diphosphate kinase 4 -2.23825
UBE3B ubiquitin protein ligase E3B -2.23817
NEO1 neogenin 1 -2.23675
PDIA5 protein disulfide isomerase family A, member 5 -2.2307
HEMK2 HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine -2.22925
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.22673
AHCY adenosylhomocysteinase -2.2267
THEM6 thioesterase superfamily member 6 -2.224
SCD stearoyl-CoA desaturase (delta-9-desaturase) -2.21871
LMAN2L lectin, mannose-binding 2-like -2.2158
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -2.2092
METTL9 methyltransferase like 9 -2.2088
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.2064
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa -2.20605
TMEM161A transmembrane protein 161A -2.2008
RFC4 replication factor C (activator 1) 4, 37kDa -2.1993
PEAK1 pseudopodium-enriched atypical kinase 1 -2.1986
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 -2.1976
BLMH bleomycin hydrolase -2.1956
ATP5IF1 ATP synthase inhibitory factor subunit 1 -2.1953
ATP7B ATPase, Cu++ transporting, beta polypeptide -2.19175
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.1886
SLC35B1 solute carrier family 35, member B1 -2.18725
PIERCE1 piercer of microtubule wall 1 -2.18542
MRPL39 mitochondrial ribosomal protein L39 -2.18465
PPIH peptidylprolyl isomerase H (cyclophilin H) -2.1839
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -2.1811
TLR5 toll-like receptor 5 -2.181
WDR70 WD repeat domain 70 -2.1782
RPN1 ribophorin I -2.168
SCARB1 scavenger receptor class B, member 1 -2.15983
KIF18A kinesin family member 18A -2.155
GPC4 glypican 4 -2.155
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 -2.1535
KNOP1 lysine-rich nucleolar protein 1 -2.15158
PPP4C protein phosphatase 4, catalytic subunit -2.15075
GEMIN6 gem (nuclear organelle) associated protein 6 -2.1498
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 -2.14905
SARS2 seryl-tRNA synthetase 2, mitochondrial -2.14825
NNT nicotinamide nucleotide transhydrogenase -2.14447
ZSCAN5A zinc finger and SCAN domain containing 5A -2.14335
B9D1 B9 protein domain 1 -2.14153
CKM creatine kinase, muscle -2.1399
EDA2R ectodysplasin A2 receptor -2.1386
PARM1 prostate androgen-regulated mucin-like protein 1 -2.13855
SPDL1 spindle apparatus coiled-coil protein 1 -2.13715
NDN necdin, melanoma antigen (MAGE) family member -2.13665
GUCY2D guanylate cyclase 2D, membrane (retina-specific) -2.1354
PSKH1 protein serine kinase H1 -2.1335
GYS1 glycogen synthase 1 (muscle) -2.132
LYZ lysozyme -2.1313
GMCL1 germ cell-less, spermatogenesis associated 1 -2.13125
B3GAT3 beta-1,3-glucuronyltransferase 3 -2.13048
AKT2 v-akt murine thymoma viral oncogene homolog 2 -2.13013
GLYAT glycine-N-acyltransferase -2.12619
PEX11A peroxisomal biogenesis factor 11 alpha -2.1258
ABI3BP ABI family, member 3 (NESH) binding protein -2.1245
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.1239
RAB1B RAB1B, member RAS oncogene family -2.1218
BST2 bone marrow stromal cell antigen 2 -2.1218
IFT52 intraflagellar transport 52 -2.1207
CDKN3 cyclin-dependent kinase inhibitor 3 -2.1202
HACL2 2-hydroxyacyl-CoA lyase 2 -2.1196
LYSET lysosomal enzyme trafficking factor -2.11875
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 -2.11855
MRPL35 mitochondrial ribosomal protein L35 -2.1166
C1QTNF3 C1q and tumor necrosis factor related protein 3 -2.1166
MVK mevalonate kinase -2.11647
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -2.1151
EFNA4 ephrin-A4 -2.11485
AURKA aurora kinase A -2.1148
NDC1 NDC1 transmembrane nucleoporin -2.1146
BGLAP bone gamma-carboxyglutamate (gla) protein -2.1138
TERT telomerase reverse transcriptase -2.1104
MRPS34 mitochondrial ribosomal protein S34 -2.10742
SNX17 sorting nexin 17 -2.1052
AUNIP aurora kinase A and ninein interacting protein -2.1046
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -2.1006
MFF mitochondrial fission factor -2.0974
MRPL34 mitochondrial ribosomal protein L34 -2.096
AAAS achalasia, adrenocortical insufficiency, alacrimia -2.0952
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa -2.09462
COQ3 coenzyme Q3 methyltransferase -2.0945
POLD2 polymerase (DNA directed), delta 2, accessory subunit -2.0907
PIAS3 protein inhibitor of activated STAT, 3 -2.08795
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -2.08785
SLC30A10 solute carrier family 30, member 10 -2.08765
ADGRB2 adhesion G protein-coupled receptor B2 -2.0869
FUS FUS RNA binding protein -2.08632
SLN sarcolipin -2.0846
DCHS2 dachsous cadherin-related 2 -2.08285
FBXO5 F-box protein 5 -2.0765
BATF3 basic leucine zipper transcription factor, ATF-like 3 -2.07395
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.07115
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 -2.0709
HEBP1 heme binding protein 1 -2.0708
EMP2 epithelial membrane protein 2 -2.0703
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 -2.06995
EXT2 exostosin glycosyltransferase 2 -2.06763
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic -2.06415
HYDIN HYDIN, axonemal central pair apparatus protein -2.064
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.0635
RAB36 RAB36, member RAS oncogene family -2.0634
KIF4A kinesin family member 4A -2.0629
CKAP2 cytoskeleton associated protein 2 -2.0611
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -2.06095
HHEX hematopoietically expressed homeobox -2.0561
IFT81 intraflagellar transport 81 -2.05495
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 -2.0545
CDO1 cysteine dioxygenase type 1 -2.05275
ACTA1 actin, alpha 1, skeletal muscle -2.052
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -2.0503
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal -2.05023
E2F1 E2F transcription factor 1 -2.05015
TPM3 tropomyosin 3 -2.04735
COMMD4 COMM domain containing 4 -2.04497
COX5B cytochrome c oxidase subunit Vb -2.04488
IVD isovaleryl-CoA dehydrogenase -2.04047
RRM2 ribonucleotide reductase M2 -2.04008
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) -2.04
SDHAF1 succinate dehydrogenase complex assembly factor 1 -2.03818
GPER1 G protein-coupled estrogen receptor 1 -2.03802
LCMT1 leucine carboxyl methyltransferase 1 -2.03575
CALCA calcitonin-related polypeptide alpha -2.03555
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -2.0333
SLC39A7 solute carrier family 39 (zinc transporter), member 7 -2.0331
NSD1 nuclear receptor binding SET domain protein 1 -2.0323
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase -2.03085
UBFD1 ubiquitin family domain containing 1 -2.02875
MPDU1 mannose-P-dolichol utilization defect 1 -2.0267
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) -2.02355
RAD51 RAD51 recombinase -2.01775
PCOLCE2 procollagen C-endopeptidase enhancer 2 -2.0168
PDF peptide deformylase (mitochondrial) -2.01505
TIPIN TIMELESS interacting protein -2.01465
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -2.01375
UNC119 unc-119 homolog (C. elegans) -2.01355
RAD51D RAD51 paralog D -2.01327
ARF5 ADP-ribosylation factor 5 -2.0065
SNRPA small nuclear ribonucleoprotein polypeptide A -2.0062
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -2.0032
FASTKD3 FAST kinase domains 3 -2.00295
BANF1 barrier to autointegration factor 1 -2.00145
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -2.0013
SPC25 SPC25, NDC80 kinetochore complex component -2.00125
HGH1 HGH1 homolog (S. cerevisiae) -2.00087