CRCGN008_HEPG2_24H:H03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description p-rosaniline.hcl 10.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

872 genes differentially expressed following the CRCGN008_HEPG2_24H:H03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
TXNRD1 thioredoxin reductase 1 10.0
INPP1 inositol polyphosphate-1-phosphatase 10.0
TRIB3 tribbles pseudokinase 3 9.5552
TIMP2 TIMP metallopeptidase inhibitor 2 8.94885
LRP10 low density lipoprotein receptor-related protein 10 7.9349
DDIT4 DNA-damage-inducible transcript 4 7.02475
GFOD1 glucose-fructose oxidoreductase domain containing 1 6.85085
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 6.79675
PHKA1 phosphorylase kinase, alpha 1 (muscle) 6.73375
FHL2 four and a half LIM domains 2 6.5473
NR1H2 nuclear receptor subfamily 1, group H, member 2 6.5344
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 6.5083
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 6.4031
ZFP36 ZFP36 ring finger protein 6.2225
FOSL1 FOS-like antigen 1 5.99175
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 5.98723
VAT1 vesicle amine transport 1 5.725
MYC v-myc avian myelocytomatosis viral oncogene homolog 5.55805
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 5.5027
IL4R interleukin 4 receptor 5.43485
ANO1 anoctamin 1, calcium activated chloride channel 5.4128
PDGFA platelet-derived growth factor alpha polypeptide 5.3334
RAB11FIP2 RAB11 family interacting protein 2 (class I) 5.3189
NPDC1 neural proliferation, differentiation and control, 1 5.2753
IER3 immediate early response 3 5.27065
MOK MOK protein kinase 5.2476
UBQLN2 ubiquilin 2 5.22505
BPHL biphenyl hydrolase-like (serine hydrolase) 5.13265
SQSTM1 sequestosome 1 5.11818
GSTZ1 glutathione S-transferase zeta 1 4.97515
ABHD4 abhydrolase domain containing 4 4.8906
KIFBP kinesin family binding protein 4.8768
CAB39 calcium binding protein 39 4.79755
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 4.7921
ADO 2-aminoethanethiol (cysteamine) dioxygenase 4.77373
ACOT9 acyl-CoA thioesterase 9 4.7534
GFPT1 glutamine--fructose-6-phosphate transaminase 1 4.75295
EGR1 early growth response 1 4.72625
ADRB2 adrenoceptor beta 2, surface 4.72055
YARS1 tyrosyl-tRNA synthetase 1 4.7055
BACE2 beta-site APP-cleaving enzyme 2 4.7027
AARS1 alanyl-tRNA synthetase 1 4.65715
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 4.65285
MVP major vault protein 4.62765
DSG2 desmoglein 2 4.5237
TES testin LIM domain protein 4.45823
CCL2 chemokine (C-C motif) ligand 2 4.4365
STX1A syntaxin 1A (brain) 4.4121
KLHL21 kelch-like family member 21 4.37845
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 4.3712
BZW2 basic leucine zipper and W2 domains 2 4.3607
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 4.3379
NMU neuromedin U 4.31305
PTK2 protein tyrosine kinase 2 4.24537
SQOR sulfide quinone oxidoreductase 4.1915
HOXA10 homeobox A10 4.12047
TRIB1 tribbles pseudokinase 1 4.1184
STXBP2 syntaxin binding protein 2 4.11335
ATF4 activating transcription factor 4 4.0956
KCNK1 potassium channel, two pore domain subfamily K, member 1 4.08175
CYCS cytochrome c, somatic 4.07115
PTPN12 protein tyrosine phosphatase, non-receptor type 12 4.02985
MACF1 microtubule-actin crosslinking factor 1 4.00591
CASC3 cancer susceptibility candidate 3 3.9519
SLC35F2 solute carrier family 35, member F2 3.8861
PPARD peroxisome proliferator-activated receptor delta 3.85577
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 3.82355
GARS1 glycyl-tRNA synthetase 1 3.7846
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 3.73055
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 3.7235
IGFBP3 insulin-like growth factor binding protein 3 3.70005
NARS1 asparaginyl-tRNA synthetase 1 3.69215
IGF2R insulin-like growth factor 2 receptor 3.68907
WDR13 WD repeat domain 13 3.64985
MICALL1 MICAL-like 1 3.64418
PCDHB11 protocadherin beta 11 3.61013
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 3.6017
GPER1 G protein-coupled estrogen receptor 1 3.5906
MBNL2 muscleblind-like splicing regulator 2 3.58638
NPC1 Niemann-Pick disease, type C1 3.5659
ITPRID2 ITPR interacting domain containing 2 3.5499
CAMTA2 calmodulin binding transcription activator 2 3.5023
PRKCQ protein kinase C, theta 3.49988
KDM6B lysine (K)-specific demethylase 6B 3.49808
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 3.49665
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 3.47985
CDK17 cyclin-dependent kinase 17 3.47252
SARS1 seryl-tRNA synthetase 1 3.47185
RALB v-ral simian leukemia viral oncogene homolog B 3.4632
SMAD3 SMAD family member 3 3.4394
CDCA4 cell division cycle associated 4 3.434
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 3.42955
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 3.4105
GLRX glutaredoxin (thioltransferase) 3.41008
PRAF2 PRA1 domain family, member 2 3.4089
TGFB1I1 transforming growth factor beta 1 induced transcript 1 3.39375
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.38225
MAPK13 mitogen-activated protein kinase 13 3.37735
TERF2IP telomeric repeat binding factor 2, interacting protein 3.32725
RRAGA Ras-related GTP binding A 3.3105
SCRN1 secernin 1 3.30995
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 3.30395
NUP58 nucleoporin 58 3.29435
PEX11A peroxisomal biogenesis factor 11 alpha 3.2779
ARL8B ADP-ribosylation factor-like 8B 3.2711
NOSIP nitric oxide synthase interacting protein 3.2421
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 3.232
PRKCD protein kinase C, delta 3.22215
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 3.20458
CARS1 cysteinyl-tRNA synthetase 1 3.2039
SNX6 sorting nexin 6 3.19545
ZMIZ1 zinc finger, MIZ-type containing 1 3.17385
CSNK1E casein kinase 1, epsilon 3.14405
TWF2 twinfilin actin binding protein 2 3.13085
TARS1 threonyl-tRNA synthetase 1 3.12625
ZZZ3 zinc finger, ZZ-type containing 3 3.1189
SRC SRC proto-oncogene, non-receptor tyrosine kinase 3.11545
ZFP69B ZFP69 zinc finger protein B 3.0897
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 3.0766
TM4SF20 transmembrane 4 L six family member 20 3.07645
GRB10 growth factor receptor-bound protein 10 3.0519
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 3.0489
MEF2B myocyte enhancer factor 2B 3.04845
BMAL2 basic helix-loop-helix ARNT like 2 3.04635
EPN2 epsin 2 3.02545
IFRD1 interferon-related developmental regulator 1 3.00975
GIPC1 GIPC PDZ domain containing family, member 1 3.0024
RAP1GAP RAP1 GTPase activating protein 3.0017
LARP6 La ribonucleoprotein domain family, member 6 3.0
EPS8L3 EPS8-like 3 2.9938
MGLL monoglyceride lipase 2.98025
RAB33A RAB33A, member RAS oncogene family 2.96795
BMP10 bone morphogenetic protein 10 2.95865
ALAS1 5'-aminolevulinate synthase 1 2.94575
INHBE inhibin, beta E 2.9382
MBNL1 muscleblind-like splicing regulator 1 2.92287
SH3GLB1 SH3-domain GRB2-like endophilin B1 2.92257
VEZT vezatin, adherens junctions transmembrane protein 2.9173
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.90845
C15ORF38-AP3S2 C15orf38-AP3S2 readthrough 2.8978
BLVRA biliverdin reductase A 2.8882
MAP7D1 MAP7 domain containing 1 2.88605
ADGRG1 adhesion G protein-coupled receptor G1 2.88565
BNC1 basonuclin 1 2.8839
CCDC68 coiled-coil domain containing 68 2.8779
ZNF589 zinc finger protein 589 2.8745
SPX spexin hormone 2.8638
ARID4B AT rich interactive domain 4B (RBP1-like) 2.83875
SHB Src homology 2 domain containing adaptor protein B 2.83463
HMGA1 high mobility group AT-hook 1 2.8291
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 2.8224
LOC128125814 uncharacterized LOC128125814 2.8155
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.81457
CD40 CD40 molecule, TNF receptor superfamily member 5 2.81374
MT1G metallothionein 1G 2.80255
PROSER1 proline and serine rich 1 2.8003
DRD1 dopamine receptor D1 2.7835
UBR4 ubiquitin protein ligase E3 component n-recognin 4 2.77978
NT5E 5'-nucleotidase, ecto (CD73) 2.7797
USP3 ubiquitin specific peptidase 3 2.77785
PPARG peroxisome proliferator-activated receptor gamma 2.7522
NANOS3 nanos homolog 3 (Drosophila) 2.7492
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 2.7408
STAP2 signal transducing adaptor family member 2 2.74045
NGRN neugrin, neurite outgrowth associated 2.73845
NR5A1 nuclear receptor subfamily 5, group A, member 1 2.727
AHNAK2 AHNAK nucleoprotein 2 2.7074
OLA1 Obg-like ATPase 1 2.70125
HOXB8 homeobox B8 2.6996
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 2.67587
ANKRD10 ankyrin repeat domain 10 2.67235
ZNF804A zinc finger protein 804A 2.6717
TRIM8 tripartite motif containing 8 2.665
PSEN1 presenilin 1 2.66358
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 2.6632
TRIM13 tripartite motif containing 13 2.64545
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 2.6433
SYNGR3 synaptogyrin 3 2.64255
CLTB clathrin, light chain B 2.64199
MEF2D myocyte enhancer factor 2D 2.63863
ZNF227 zinc finger protein 227 2.63215
RAB8B RAB8B, member RAS oncogene family 2.6314
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.6267
CSRNP3 cysteine-serine-rich nuclear protein 3 2.62165
KIF13B kinesin family member 13B 2.61935
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 2.6155
ZYX zyxin 2.61048
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 2.60993
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 2.60865
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 2.60085
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.59975
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 2.59445
DNAH17 dynein, axonemal, heavy chain 17 2.592
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 2.58645
MSI1 musashi RNA-binding protein 1 2.5854
TNIP2 TNFAIP3 interacting protein 2 2.5802
LGALS8 lectin, galactoside-binding, soluble, 8 2.57733
ZBTB35 zinc finger and BTB domain containing 35 2.57338
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 2.56705
CDA cytidine deaminase 2.56585
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 2.5537
GNPAT glyceronephosphate O-acyltransferase 2.5479
NCK1 NCK adaptor protein 1 2.54657
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.54645
IL37 interleukin 37 2.54235
TFE3 transcription factor binding to IGHM enhancer 3 2.5334
TP53BP2 tumor protein p53 binding protein 2 2.5291
G0S2 G0/G1 switch 2 2.5277
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 2.52165
LAD1 ladinin 1 2.51675
DCAF4 DDB1 and CUL4 associated factor 4 2.5113
ANKRD11 ankyrin repeat domain 11 2.51075
H2BC21 H2B clustered histone 21 2.51065
PRKN parkin RBR E3 ubiquitin protein ligase 2.50885
CAB39L calcium binding protein 39-like 2.50435
C2CD2 C2 calcium-dependent domain containing 2 2.4995
MCOLN3 mucolipin 3 2.4938
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.4921
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.49015
PLXNB3 plexin B3 2.48695
IST1 increased sodium tolerance 1 homolog (yeast) 2.4858
BRSK2 BR serine/threonine kinase 2 2.4842
IRX4 iroquois homeobox 4 2.48385
HPSE heparanase 2.47855
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.47682
GADD45B growth arrest and DNA-damage-inducible, beta 2.47362
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.46705
SPINT1 serine peptidase inhibitor, Kunitz type 1 2.4589
WARS1 tryptophanyl-tRNA synthetase 1 2.45758
NRBF2 nuclear receptor binding factor 2 2.4575
ITGB5 integrin, beta 5 2.45652
GDI1 GDP dissociation inhibitor 1 2.45505
DNMBP dynamin binding protein 2.448
MBTD1 mbt domain containing 1 2.4456
SLC38A2 solute carrier family 38, member 2 2.44413
CRX cone-rod homeobox 2.4435
SMTN smoothelin 2.4413
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 2.4402
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.4369
CLIP2 CAP-GLY domain containing linker protein 2 2.4357
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 2.43552
LGALS4 lectin, galactoside-binding, soluble, 4 2.42985
UGDH UDP-glucose 6-dehydrogenase 2.42745
TOMM34 translocase of outer mitochondrial membrane 34 2.42555
ATF6 activating transcription factor 6 2.42445
N4BP3 NEDD4 binding protein 3 2.4235
DOCK6 dedicator of cytokinesis 6 2.42302
ITPKA inositol-trisphosphate 3-kinase A 2.4226
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 2.42123
DUSP6 dual specificity phosphatase 6 2.41962
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 2.4192
CDK7 cyclin-dependent kinase 7 2.40845
FNTA farnesyltransferase, CAAX box, alpha 2.4066
ASNS asparagine synthetase (glutamine-hydrolyzing) 2.40425
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 2.40165
PXDC1 PX domain containing 1 2.40045
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.396
MAGIX MAGI family member, X-linked 2.3949
THSD7A thrombospondin, type I, domain containing 7A 2.39088
IMP4 IMP4, U3 small nucleolar ribonucleoprotein 2.3866
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 2.3861
IL36R interleukin 36 receptor 2.38585
ELF4 E74-like factor 4 (ets domain transcription factor) 2.3858
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 2.38455
CEP170B centrosomal protein 170B 2.3819
ZNF141 zinc finger protein 141 2.37725
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 2.37537
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 2.3692
VAC14 Vac14 homolog (S. cerevisiae) 2.3686
MYH9 myosin, heavy chain 9, non-muscle 2.368
TMC7 transmembrane channel-like 7 2.3672
CDCP1 CUB domain containing protein 1 2.3649
LPGAT1 lysophosphatidylglycerol acyltransferase 1 2.36315
ZFAND1 zinc finger, AN1-type domain 1 2.3616
ADGRE5 adhesion G protein-coupled receptor E5 2.35765
TFF2 trefoil factor 2 2.35715
GRM3 glutamate receptor, metabotropic 3 2.3529
GTPBP2 GTP binding protein 2 2.3462
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B 2.3446
PCNP PEST proteolytic signal containing nuclear protein 2.342
TSC22D3 TSC22 domain family, member 3 2.3353
RAB9A RAB9A, member RAS oncogene family 2.33195
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 2.3281
RAB3B RAB3B, member RAS oncogene family 2.32505
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent 2.3241
ZC3H15 zinc finger CCCH-type containing 15 2.3157
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 2.31495
HOMER2 homer scaffolding protein 2 2.31421
MSN moesin 2.30865
DBN1 drebrin 1 2.30608
CAMKV CaM kinase-like vesicle-associated 2.3033
KIFC3 kinesin family member C3 2.30055
UFM1 ubiquitin-fold modifier 1 2.29685
P2RY10 purinergic receptor P2Y, G-protein coupled, 10 2.289
LRRC8B leucine rich repeat containing 8 family, member B 2.2885
DENND4C DENN/MADD domain containing 4C 2.28785
IER2 immediate early response 2 2.2857
SMIM44 small integral membrane protein 44 2.2823
VGLL4 vestigial-like family member 4 2.2796
H2BC6 H2B clustered histone 6 2.2792
EHD2 EH-domain containing 2 2.27842
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.2772
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 2.275
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.27325
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.2715
ZFP36L1 ZFP36 ring finger protein-like 1 2.27082
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 2.26815
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 2.26555
MAP3K9 mitogen-activated protein kinase kinase kinase 9 2.26533
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 2.26435
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 2.26425
EHMT1 euchromatic histone-lysine N-methyltransferase 1 2.2637
ADAP2 ArfGAP with dual PH domains 2 2.2599
MIDEAS mitotic deacetylase associated SANT domain protein 2.25685
RHOG ras homolog family member G 2.25545
SART1 squamous cell carcinoma antigen recognized by T cells 2.252
KDM5A lysine (K)-specific demethylase 5A 2.24732
CLCF1 cardiotrophin-like cytokine factor 1 2.2473
PPP1R26 protein phosphatase 1, regulatory subunit 26 2.24205
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 2.23875
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 2.23835
TNIP1 TNFAIP3 interacting protein 1 2.23775
PHOSPHO2-KLHL23 PHOSPHO2-KLHL23 readthrough 2.2354
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 2.2297
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 2.22935
LONRF3 LON peptidase N-terminal domain and ring finger 3 2.22875
ARHGAP22 Rho GTPase activating protein 22 2.22615
NCKAP1 NCK-associated protein 1 2.226
ZSCAN9 zinc finger and SCAN domain containing 9 2.2257
ARL14 ADP-ribosylation factor-like 14 2.22405
MT1H metallothionein 1H 2.2232
HEATR1 HEAT repeat containing 1 2.22038
MUC13 mucin 13, cell surface associated 2.2199
HKDC1 hexokinase domain containing 1 2.2186
SCRT1 scratch family zinc finger 1 2.2168
INF2 inverted formin, FH2 and WH2 domain containing 2.21595
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 2.2157
PPIL6 peptidylprolyl isomerase (cyclophilin)-like 6 2.2126
SOX4 SRY (sex determining region Y)-box 4 2.21005
CRYBA4 crystallin, beta A4 2.2084
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 2.20615
ACVR1 activin A receptor, type I 2.2035
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) 2.20303
PTPRF protein tyrosine phosphatase, receptor type, F 2.20083
RUFY1 RUN and FYVE domain containing 1 2.1973
PLA2G2F phospholipase A2, group IIF 2.19305
MYO5A myosin VA (heavy chain 12, myoxin) 2.19205
MRPS22 mitochondrial ribosomal protein S22 2.1917
PLK3 polo-like kinase 3 2.186
ZXDB zinc finger, X-linked, duplicated B 2.185
MCHR1 melanin-concentrating hormone receptor 1 2.18315
FGF20 fibroblast growth factor 20 2.1797
TEAD3 TEA domain family member 3 2.17365
VSIG2 V-set and immunoglobulin domain containing 2 2.1736
EPRS1 glutamyl-prolyl-tRNA synthetase 1 2.17242
CNTNAP3B contactin associated protein-like 3B 2.17155
EHD4 EH-domain containing 4 2.1703
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 2.1686
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 2.168
SEC62 SEC62 homolog (S. cerevisiae) 2.16157
TM4SF4 transmembrane 4 L six family member 4 2.1604
RB1CC1 RB1-inducible coiled-coil 1 2.15885
KLHL4 kelch-like family member 4 2.15715
IARS1 isoleucyl-tRNA synthetase 1 2.15655
LCOR ligand dependent nuclear receptor corepressor 2.14945
MEP1B meprin A, beta 2.1489
TMEM156 transmembrane protein 156 2.1477
ZNF682 zinc finger protein 682 2.14685
SLC35F5 solute carrier family 35, member F5 2.14485
SPMAP2 sperm microtubule associated protein 2 2.14125
RAP1A RAP1A, member of RAS oncogene family 2.13915
RPF1 ribosome production factor 1 homolog (S. cerevisiae) 2.13665
OXCT2 3-oxoacid CoA transferase 2 2.13605
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2 2.1345
YY1AP1 YY1 associated protein 1 2.1335
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 2.1302
CCDC92 coiled-coil domain containing 92 2.12965
SPATA1 spermatogenesis associated 1 2.1281
PAQR5 progestin and adipoQ receptor family member V 2.128
ELOA2 elongin A2 2.12725
THAP9 THAP domain containing 9 2.12565
RBM41 RNA binding motif protein 41 2.1215
HOOK1 hook microtubule-tethering protein 1 2.1208
TMEM19 transmembrane protein 19 2.1172
MKNK2 MAP kinase interacting serine/threonine kinase 2 2.11715
POGK pogo transposable element with KRAB domain 2.1171
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 2.11605
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 2.11478
DSG1 desmoglein 1 2.1144
OSGIN2 oxidative stress induced growth inhibitor family member 2 2.1113
JAK1 Janus kinase 1 2.11055
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 2.11035
YIPF4 Yip1 domain family, member 4 2.1099
FURIN furin (paired basic amino acid cleaving enzyme) 2.1053
ZNF410 zinc finger protein 410 2.10375
IL2 interleukin 2 2.10375
GABPB1 GA binding protein transcription factor, beta subunit 1 2.1032
AADAC arylacetamide deacetylase 2.1024
CYTH2 cytohesin 2 2.1009
TLN1 talin 1 2.0976
DOHH deoxyhypusine hydroxylase/monooxygenase 2.0972
KIAA0408 KIAA0408 2.0964
FBXO28 F-box protein 28 2.09597
DOP1B DOP1 leucine zipper like protein B 2.09427
GTF2IRD1 GTF2I repeat domain containing 1 2.09355
TXLNG taxilin gamma 2.09265
PORCN porcupine homolog (Drosophila) 2.0914
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) 2.0866
ZNF585B zinc finger protein 585B 2.08505
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 2.081
CMKLR2 chemerin chemokine-like receptor 2 2.07975
LBP lipopolysaccharide binding protein 2.07865
GLRX2 glutaredoxin 2 2.0748
UNC13D unc-13 homolog D (C. elegans) 2.07415
CRIP2 cysteine-rich protein 2 2.07395
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 2.07205
HSPB6 heat shock protein, alpha-crystallin-related, B6 2.07055
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.0701
EFNA2 ephrin-A2 2.06995
ZNF132 zinc finger protein 132 2.06995
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.06632
KIF24 kinesin family member 24 2.0655
MBD1 methyl-CpG binding domain protein 1 2.0638
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 2.06305
CIDEA cell death-inducing DFFA-like effector a 2.06165
GBE1 glucan (1,4-alpha-), branching enzyme 1 2.06035
FEZF2 FEZ family zinc finger 2 2.06025
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 2.05815
CTAGE8 CTAGE family, member 8 2.0574
ARL5A ADP-ribosylation factor-like 5A 2.0562
CPEB1 cytoplasmic polyadenylation element binding protein 1 2.0556
KISS1 KiSS-1 metastasis-suppressor 2.05545
WNT3 wingless-type MMTV integration site family, member 3 2.05505
PSAT1 phosphoserine aminotransferase 1 2.0547
GNB5 guanine nucleotide binding protein (G protein), beta 5 2.05242
SGPP1 sphingosine-1-phosphate phosphatase 1 2.051
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa 2.0496
MTMR11 myotubularin related protein 11 2.04865
ETV3 ets variant 3 2.04395
PROCR protein C receptor, endothelial 2.04355
IL1RAPL2 interleukin 1 receptor accessory protein-like 2 2.0431
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2.0421
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 2.04185
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 2.0411
PRDM14 PR domain containing 14 2.04025
LIM2 lens intrinsic membrane protein 2, 19kDa 2.03405
MT1M metallothionein 1M 2.034
PCDH11X protocadherin 11 X-linked 2.03027
RRAGC Ras-related GTP binding C 2.02985
TLK2 tousled-like kinase 2 2.02975
BECN1 beclin 1, autophagy related 2.0297
ACTN4 actinin, alpha 4 2.0276
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 2.02413
CCL27 chemokine (C-C motif) ligand 27 2.0238
AIRIM AFG2 interacting ribosome maturation factor 2.02185
AOC1 amine oxidase, copper containing 1 2.0195
CCL22 chemokine (C-C motif) ligand 22 2.01925
UBE2H ubiquitin-conjugating enzyme E2H 2.01895
WASHC4 WASH complex subunit 4 2.01742
ALX3 ALX homeobox 3 2.01715
EGFR epidermal growth factor receptor 2.01691
FILIP1L filamin A interacting protein 1-like 2.01575
UNC93A unc-93 homolog A (C. elegans) 2.01475
CSDC2 cold shock domain containing C2, RNA binding 2.01325
LRP1B low density lipoprotein receptor-related protein 1B 2.0096
CHRM2 cholinergic receptor, muscarinic 2 2.00895
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 2.00855
RTN2 reticulon 2 2.0082
GNA13 guanine nucleotide binding protein (G protein), alpha 13 2.0082
OR10H3 olfactory receptor, family 10, subfamily H, member 3 2.0079
PURG purine-rich element binding protein G 2.00765
PLA2R1 phospholipase A2 receptor 1, 180kDa 2.00525
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 2.0051
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.00125

decreased expression

Symbol Name Standardized Value
TCTN1 tectonic family member 1 -10.0
B4GAT1 beta-1,4-glucuronyltransferase 1 -9.7033
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -8.9033
ISOC1 isochorismatase domain containing 1 -8.80745
ICAM3 intercellular adhesion molecule 3 -8.7675
ALDOC aldolase C, fructose-bisphosphate -8.4477
CD320 CD320 molecule -8.28575
NT5DC2 5'-nucleotidase domain containing 2 -7.85335
PGM1 phosphoglucomutase 1 -7.8317
COG7 component of oligomeric golgi complex 7 -7.4893
ZW10 zw10 kinetochore protein -7.27405
CDC20 cell division cycle 20 -7.21505
CCNA2 cyclin A2 -7.1238
STMN1 stathmin 1 -6.9557
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -6.8878
AURKB aurora kinase B -6.83285
TCTA T-cell leukemia translocation altered -6.7446
MELK maternal embryonic leucine zipper kinase -6.7142
PSRC1 proline/serine-rich coiled-coil 1 -6.69525
TMEM97 transmembrane protein 97 -6.60791
CETN3 centrin, EF-hand protein, 3 -6.48645
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -6.48035
TARBP1 TAR (HIV-1) RNA binding protein 1 -6.2745
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -6.14248
PGAM4 phosphoglycerate mutase family member 4 -6.06555
PLK1 polo-like kinase 1 -6.02675
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -5.99675
TMEM109 transmembrane protein 109 -5.96955
NFIL3 nuclear factor, interleukin 3 regulated -5.93605
HSPA1A heat shock 70kDa protein 1A -5.9021
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -5.87115
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -5.80885
MLEC malectin -5.7112
CDK1 cyclin-dependent kinase 1 -5.64778
NLRP2B NLR family pyrin domain containing 2B -5.64085
CCNB1 cyclin B1 -5.602
HAT1 histone acetyltransferase 1 -5.42135
TOP2A topoisomerase (DNA) II alpha 170kDa -5.39663
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -5.2853
PCNA proliferating cell nuclear antigen -5.2706
BIRC5 baculoviral IAP repeat containing 5 -5.2665
CTSL cathepsin L -5.2225
PARP1 poly (ADP-ribose) polymerase 1 -5.1963
DERA deoxyribose-phosphate aldolase (putative) -5.09065
DCK deoxycytidine kinase -4.9154
NUP85 nucleoporin 85kDa -4.89685
GLOD4 glyoxalase domain containing 4 -4.7265
ADI1 acireductone dioxygenase 1 -4.72065
BCL7C B-cell CLL/lymphoma 7C -4.6823
SOAT2 sterol O-acyltransferase 2 -4.67938
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -4.5643
CHEK2 checkpoint kinase 2 -4.4657
HSPB1 heat shock 27kDa protein 1 -4.44985
NUCB2 nucleobindin 2 -4.44625
POLR1A polymerase (RNA) I polypeptide A, 194kDa -4.43773
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -4.4253
TRIP13 thyroid hormone receptor interactor 13 -4.3872
MYCBP MYC binding protein -4.36862
DDB2 damage-specific DNA binding protein 2, 48kDa -4.3561
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -4.33135
ASF1B anti-silencing function 1B histone chaperone -4.32825
TEDC2 tubulin epsilon and delta complex 2 -4.32395
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -4.29192
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -4.1504
ACAA1 acetyl-CoA acyltransferase 1 -4.08497
FEN1 flap structure-specific endonuclease 1 -4.06233
TBC1D10C TBC1 domain family, member 10C -3.9851
RPA3 replication protein A3, 14kDa -3.9836
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -3.95048
GTF2A2 general transcription factor IIA, 2, 12kDa -3.91755
MIS18A MIS18 kinetochore protein A -3.9125
LMNB1 lamin B1 -3.86605
THAP11 THAP domain containing 11 -3.84985
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -3.76765
HADH hydroxyacyl-CoA dehydrogenase -3.74717
PRPF4 pre-mRNA processing factor 4 -3.70905
LAGE3 L antigen family, member 3 -3.6836
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -3.67645
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -3.67335
PAGR1 PAXIP1 associated glutamate-rich protein 1 -3.6559
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -3.6254
SLC39A7 solute carrier family 39 (zinc transporter), member 7 -3.6235
MRPL12 mitochondrial ribosomal protein L12 -3.61745
UBE3C ubiquitin protein ligase E3C -3.61575
CDCA3 cell division cycle associated 3 -3.60575
SDF2L1 stromal cell-derived factor 2-like 1 -3.6041
UBE2C ubiquitin-conjugating enzyme E2C -3.6015
GLT8D1 glycosyltransferase 8 domain containing 1 -3.5783
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -3.57295
GMNN geminin, DNA replication inhibitor -3.54993
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -3.54255
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -3.51825
AMDHD2 amidohydrolase domain containing 2 -3.49955
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.4947
TFDP1 transcription factor Dp-1 -3.45243
S100A4 S100 calcium binding protein A4 -3.44835
KIF15 kinesin family member 15 -3.44195
CENPS-CORT CENPS-CORT readthrough -3.41885
CASP3 caspase 3, apoptosis-related cysteine peptidase -3.4101
CENPM centromere protein M -3.40995
CDC25B cell division cycle 25B -3.4085
CDC45 cell division cycle 45 -3.39435
TMEM106C transmembrane protein 106C -3.39395
TSPAN6 tetraspanin 6 -3.38877
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -3.38552
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.3499
PYCR3 pyrroline-5-carboxylate reductase 3 -3.3473
NUP93 nucleoporin 93kDa -3.3473
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -3.33135
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -3.3262
MCM10 minichromosome maintenance complex component 10 -3.3254
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -3.30815
TRAP1 TNF receptor-associated protein 1 -3.3073
ZNF200 zinc finger protein 200 -3.28912
GINS2 GINS complex subunit 2 (Psf2 homolog) -3.28615
SCGB1D1 secretoglobin, family 1D, member 1 -3.27373
SLC2A4RG SLC2A4 regulator -3.27205
BDH1 3-hydroxybutyrate dehydrogenase, type 1 -3.27085
KIFC1 kinesin family member C1 -3.25495
FANCG Fanconi anemia, complementation group G -3.2534
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -3.24575
RPIA ribose 5-phosphate isomerase A -3.23455
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -3.2117
ECH1 enoyl CoA hydratase 1, peroxisomal -3.19765
PGRMC1 progesterone receptor membrane component 1 -3.19397
LGMN legumain -3.18675
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.1858
CD58 CD58 molecule -3.18445
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -3.1663
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.16525
GAMT guanidinoacetate N-methyltransferase -3.1197
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -3.11465
DHFR dihydrofolate reductase -3.08054
GINS1 GINS complex subunit 1 (Psf1 homolog) -3.06325
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.0604
IDI1 isopentenyl-diphosphate delta isomerase 1 -3.04627
HEBP1 heme binding protein 1 -3.03875
VAV3 vav 3 guanine nucleotide exchange factor -3.03305
ARHGAP19 Rho GTPase activating protein 19 -3.02132
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -3.0185
TARBP2 TAR (HIV-1) RNA binding protein 2 -3.01485
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -3.00115
CCNF cyclin F -3.001
CETN2 centrin, EF-hand protein, 2 -2.97825
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.9645
PRR5 proline rich 5 (renal) -2.9551
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.95095
MSMO1 methylsterol monooxygenase 1 -2.9434
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.93408
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -2.93135
ERI2 ERI1 exoribonuclease family member 2 -2.92145
HSPA8 heat shock 70kDa protein 8 -2.91382
CENPX centromere protein X -2.9083
RBM14-RBM4 RBM14-RBM4 readthrough -2.9062
PRR7 proline rich 7 (synaptic) -2.9018
FGFR4 fibroblast growth factor receptor 4 -2.89563
TMCO1 transmembrane and coiled-coil domains 1 -2.89177
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -2.8861
TMEM14A transmembrane protein 14A -2.8843
KIF11 kinesin family member 11 -2.8827
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -2.87175
S100PBP S100P binding protein -2.86385
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -2.858
H2AX H2A.X variant histone -2.85605
HIRIP3 HIRA interacting protein 3 -2.84955
BLCAP bladder cancer associated protein -2.84545
SPAG5 sperm associated antigen 5 -2.8409
ERCC6L excision repair cross-complementation group 6-like -2.83845
DSCC1 DNA replication and sister chromatid cohesion 1 -2.82515
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -2.81693
PARN poly(A)-specific ribonuclease -2.79665
ZNF274 zinc finger protein 274 -2.78725
THADA thyroid adenoma associated -2.7812
HIRA histone cell cycle regulator -2.78095
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 -2.77865
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.76855
ANAPC15 anaphase promoting complex subunit 15 -2.7665
PROS1 protein S (alpha) -2.7565
CDC6 cell division cycle 6 -2.7564
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -2.75475
TTC12 tetratricopeptide repeat domain 12 -2.733
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa -2.7161
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.6998
TROAP trophinin associated protein -2.69615
MSH6 mutS homolog 6 -2.69357
MGST2 microsomal glutathione S-transferase 2 -2.6912
NCAPD2 non-SMC condensin I complex, subunit D2 -2.68515
DCPS decapping enzyme, scavenger -2.6812
MSH2 mutS homolog 2 -2.67795
CRELD2 cysteine-rich with EGF-like domains 2 -2.66745
PDIA5 protein disulfide isomerase family A, member 5 -2.66445
UNC119B unc-119 homolog B (C. elegans) -2.65275
KIF4A kinesin family member 4A -2.63775
SAC3D1 SAC3 domain containing 1 -2.6336
RBM15B RNA binding motif protein 15B -2.6318
SMCO4 single-pass membrane protein with coiled-coil domains 4 -2.63
LBR lamin B receptor -2.62395
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.6236
UBL5 ubiquitin-like 5 -2.6209
DGCR6L DiGeorge syndrome critical region gene 6-like -2.61645
COLGALT1 collagen beta(1-O)galactosyltransferase 1 -2.6164
THAP7 THAP domain containing 7 -2.6137
NCAPD3 non-SMC condensin II complex, subunit D3 -2.60945
DBF4 DBF4 zinc finger -2.60525
SNX17 sorting nexin 17 -2.59745
LMF2 lipase maturation factor 2 -2.58838
PPIH peptidylprolyl isomerase H (cyclophilin H) -2.5822
TK1 thymidine kinase 1, soluble -2.5697
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.56745
SCML2 sex comb on midleg-like 2 (Drosophila) -2.5628
CHMP6 charged multivesicular body protein 6 -2.5592
ARB2A ARB2 cotranscriptional regulator A -2.5487
GTF2H5 general transcription factor IIH, polypeptide 5 -2.5432
DEXI Dexi homolog (mouse) -2.54035
DONSON downstream neighbor of SON -2.5372
SPDEF SAM pointed domain containing ETS transcription factor -2.53533
GMPPB GDP-mannose pyrophosphorylase B -2.533
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.5303
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -2.52822
STIMATE STIM activating enhancer -2.52775
NCAPH non-SMC condensin I complex, subunit H -2.5231
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.51635
RACGAP1 Rac GTPase activating protein 1 -2.50925
NTHL1 nth endonuclease III-like 1 (E. coli) -2.50835
RMI1 RecQ mediated genome instability 1 -2.50725
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -2.50275
SORD sorbitol dehydrogenase -2.5001
ATAD3A ATPase family, AAA domain containing 3A -2.49585
BMP4 bone morphogenetic protein 4 -2.49
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit -2.48647
NME4 NME/NM23 nucleoside diphosphate kinase 4 -2.4789
SH3D19 SH3 domain containing 19 -2.47215
FANCI Fanconi anemia, complementation group I -2.4653
ORC6 origin recognition complex, subunit 6 -2.45985
CCNE1 cyclin E1 -2.45905
CBR1 carbonyl reductase 1 -2.45785
DHCR7 7-dehydrocholesterol reductase -2.45192
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 -2.4441
PDIA4 protein disulfide isomerase family A, member 4 -2.4433
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -2.44283
CCDC85B coiled-coil domain containing 85B -2.4411
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -2.43665
CRADD CASP2 and RIPK1 domain containing adaptor with death domain -2.43415
UNC119 unc-119 homolog (C. elegans) -2.42845
TERT telomerase reverse transcriptase -2.4233
CKS1B CDC28 protein kinase regulatory subunit 1B -2.42215
VRK1 vaccinia related kinase 1 -2.4158
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) -2.41575
ICMT isoprenylcysteine carboxyl methyltransferase -2.4107
KIF18B kinesin family member 18B -2.41035
ELP5 elongator acetyltransferase complex subunit 5 -2.4088
PALB2 partner and localizer of BRCA2 -2.408
TMPO thymopoietin -2.40105
FZD7 frizzled class receptor 7 -2.39965
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.39945
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.39653
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -2.3947
CHIC2 cysteine-rich hydrophobic domain 2 -2.39405
PRUNE1 prune exopolyphosphatase 1 -2.39163
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.38792
CDK4 cyclin-dependent kinase 4 -2.38735
RFC5 replication factor C (activator 1) 5, 36.5kDa -2.38695
KIF22 kinesin family member 22 -2.38635
FASTKD5 FAST kinase domains 5 -2.38245
LIME1 Lck interacting transmembrane adaptor 1 -2.37325
TRMT5 tRNA methyltransferase 5 -2.36495
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -2.36438
PCCB propionyl CoA carboxylase, beta polypeptide -2.3624
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 -2.36185
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.35612
MRPS7 mitochondrial ribosomal protein S7 -2.35105
RALY RALY heterogeneous nuclear ribonucleoprotein -2.3461
CNOT9 CCR4-NOT transcription complex subunit 9 -2.34525
RXRA retinoid X receptor, alpha -2.34065
TSEN2 TSEN2 tRNA splicing endonuclease subunit -2.33795
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.33575
RBX1 ring-box 1, E3 ubiquitin protein ligase -2.33555
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.33245
SRSF9 serine/arginine-rich splicing factor 9 -2.332
MAGEC2 melanoma antigen family C2 -2.3201
NAGA N-acetylgalactosaminidase, alpha- -2.31745
COQ3 coenzyme Q3 methyltransferase -2.3143
ASB13 ankyrin repeat and SOCS box containing 13 -2.3121
NNT nicotinamide nucleotide transhydrogenase -2.3085
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) -2.3078
SPA17 sperm autoantigenic protein 17 -2.30535
MRPL17 mitochondrial ribosomal protein L17 -2.30305
NUP37 nucleoporin 37kDa -2.30245
WNT5A wingless-type MMTV integration site family, member 5A -2.30198
PIMREG PICALM interacting mitotic regulator -2.2988
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -2.2931
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.2872
TSKU tsukushi, small leucine rich proteoglycan -2.2852
XPO1 exportin 1 -2.28215
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 -2.2802
HMGA2 high mobility group AT-hook 2 -2.2795
MLF1 myeloid leukemia factor 1 -2.27877
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 -2.26645
RAB36 RAB36, member RAS oncogene family -2.25715
PECR peroxisomal trans-2-enoyl-CoA reductase -2.2546
RAD54L RAD54-like (S. cerevisiae) -2.2504
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -2.24785
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.24488
DENND1C DENN/MADD domain containing 1C -2.24455
MXRA7 matrix-remodelling associated 7 -2.2435
ANXA6 annexin A6 -2.23645
NUP107 nucleoporin 107kDa -2.2363
NIPSNAP1 nipsnap homolog 1 (C. elegans) -2.23228
IQSEC1 IQ motif and Sec7 domain 1 -2.22892
SAMM50 SAMM50 sorting and assembly machinery component -2.22235
THEM6 thioesterase superfamily member 6 -2.22135
TGFB3 transforming growth factor, beta 3 -2.21925
FAM111A family with sequence similarity 111, member A -2.21645
VCAM1 vascular cell adhesion molecule 1 -2.2152
KDM1A lysine (K)-specific demethylase 1A -2.21375
ORC3 origin recognition complex, subunit 3 -2.21215
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.2114
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 -2.21135
NEK4 NIMA-related kinase 4 -2.2108
HHAT hedgehog acyltransferase -2.2088
ABHD14A abhydrolase domain containing 14A -2.20475
C2CD5 C2 calcium-dependent domain containing 5 -2.20075
CAND1 cullin-associated and neddylation-dissociated 1 -2.1996
MANF mesencephalic astrocyte-derived neurotrophic factor -2.19955
ARMC6 armadillo repeat containing 6 -2.19775
SESN1 sestrin 1 -2.195
CCS copper chaperone for superoxide dismutase -2.1935
CD99 CD99 molecule -2.19005
TIMELESS timeless circadian clock -2.18765
AMT aminomethyltransferase -2.1838
OIP5 Opa interacting protein 5 -2.1834
PUF60 poly-U binding splicing factor 60KDa -2.1819
HMBS hydroxymethylbilane synthase -2.18012
ASB9 ankyrin repeat and SOCS box containing 9 -2.17975
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -2.1785
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.1756
PDZD2 PDZ domain containing 2 -2.17558
COL3A1 collagen, type III, alpha 1 -2.1723
DSN1 DSN1, MIS12 kinetochore complex component -2.1703
MTFR1 mitochondrial fission regulator 1 -2.1702
DUT deoxyuridine triphosphatase -2.17017
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -2.16512
TRAPPC4 trafficking protein particle complex 4 -2.1619
THAP12 THAP domain containing 12 -2.16145
KAT8 K(lysine) acetyltransferase 8 -2.16015
RHBG Rh family, B glycoprotein (gene/pseudogene) -2.15695
MCM5 minichromosome maintenance complex component 5 -2.15692
NAAA N-acylethanolamine acid amidase -2.15155
SFXN1 sideroflexin 1 -2.1488
FBXL4 F-box and leucine-rich repeat protein 4 -2.14875
FBXL12 F-box and leucine-rich repeat protein 12 -2.1447
DROSHA drosha, ribonuclease type III -2.1401
UBE3B ubiquitin protein ligase E3B -2.13423
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -2.1334
CEP43 centrosomal protein 43 -2.1285
SCAND1 SCAN domain containing 1 -2.1225
LYRM9 LYR motif containing 9 -2.12215
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.11825
ANKRD17 ankyrin repeat domain 17 -2.1135
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -2.11235
NCAPG2 non-SMC condensin II complex, subunit G2 -2.11195
CFAP20 cilia and flagella associated protein 20 -2.11045
PPP4C protein phosphatase 4, catalytic subunit -2.1102
S100A1 S100 calcium binding protein A1 -2.1068
PPT2 palmitoyl-protein thioesterase 2 -2.09735
DCTPP1 dCTP pyrophosphatase 1 -2.0965
TM7SF3 transmembrane 7 superfamily member 3 -2.0891
GALK1 galactokinase 1 -2.07555
UXT ubiquitously-expressed, prefoldin-like chaperone -2.07209
TCEA2 transcription elongation factor A (SII), 2 -2.05285
PNPO pyridoxamine 5'-phosphate oxidase -2.0518
IRX5 iroquois homeobox 5 -2.0473
UROS uroporphyrinogen III synthase -2.04525
ACYP1 acylphosphatase 1, erythrocyte (common) type -2.0438
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 -2.0432
WRAP53 WD repeat containing, antisense to TP53 -2.04278
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase -2.0412
LIPC lipase, hepatic -2.0395
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 -2.0393
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -2.03205
PBK PDZ binding kinase -2.0317
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -2.03145
UNG uracil-DNA glycosylase -2.0258
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.0245
ERI3 ERI1 exoribonuclease family member 3 -2.02345
DHRS2 dehydrogenase/reductase (SDR family) member 2 -2.02087
PGAP2 post-GPI attachment to proteins 2 -2.0194
RWDD3 RWD domain containing 3 -2.01745
ATP7B ATPase, Cu++ transporting, beta polypeptide -2.0174
RAD51AP1 RAD51 associated protein 1 -2.01615
FUS FUS RNA binding protein -2.01533
RFC3 replication factor C (activator 1) 3, 38kDa -2.01468
RNASE7 ribonuclease, RNase A family, 7 -2.01172
IFT88 intraflagellar transport 88 -2.01015
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -2.0089
MRS2 MRS2 magnesium transporter -2.00557
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.0044