CRCGN008_HEPG2_24H:H05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description p-rosaniline.hcl 2.5 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

445 genes differentially expressed following the CRCGN008_HEPG2_24H:H05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 9.3341
INPP1 inositol polyphosphate-1-phosphatase 7.883
TIMP2 TIMP metallopeptidase inhibitor 2 7.4373
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 7.13885
LRP10 low density lipoprotein receptor-related protein 10 6.5126
CNPY3 canopy FGF signaling regulator 3 6.3977
DDIT4 DNA-damage-inducible transcript 4 5.8441
EGR1 early growth response 1 5.71693
ZFP36 ZFP36 ring finger protein 5.3839
NPDC1 neural proliferation, differentiation and control, 1 5.3172
NMU neuromedin U 5.2836
BZW2 basic leucine zipper and W2 domains 2 5.1354
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 5.0924
BACE2 beta-site APP-cleaving enzyme 2 5.049
SQSTM1 sequestosome 1 4.97368
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 4.9023
CTSL cathepsin L 4.85665
MYLK myosin light chain kinase 4.74385
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 4.6867
GRB10 growth factor receptor-bound protein 10 4.5619
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 4.5186
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.5164
VAT1 vesicle amine transport 1 4.49515
TXNRD1 thioredoxin reductase 1 4.4848
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 4.41025
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 4.29335
CHMP6 charged multivesicular body protein 6 4.1351
MYC v-myc avian myelocytomatosis viral oncogene homolog 4.129
KCNK1 potassium channel, two pore domain subfamily K, member 1 4.10378
CASP10 caspase 10, apoptosis-related cysteine peptidase 4.08764
IER3 immediate early response 3 4.0817
PRKCH protein kinase C, eta 4.0718
MBNL2 muscleblind-like splicing regulator 2 4.05905
ADO 2-aminoethanethiol (cysteamine) dioxygenase 4.01685
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 3.93543
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 3.8309
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 3.7974
JADE2 jade family PHD finger 2 3.56397
DUSP6 dual specificity phosphatase 6 3.54968
DSG2 desmoglein 2 3.5435
ACOT9 acyl-CoA thioesterase 9 3.49105
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 3.4686
FOSL1 FOS-like antigen 1 3.43595
ATF4 activating transcription factor 4 3.39465
TRIB1 tribbles pseudokinase 1 3.3389
YARS1 tyrosyl-tRNA synthetase 1 3.3183
PHGDH phosphoglycerate dehydrogenase 3.31107
IL4R interleukin 4 receptor 3.27575
CASC3 cancer susceptibility candidate 3 3.26155
ELL2 elongation factor, RNA polymerase II, 2 3.2588
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 3.2576
VAV3 vav 3 guanine nucleotide exchange factor 3.25577
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 3.2015
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 3.11
ASL argininosuccinate lyase 3.0743
MX1 MX dynamin-like GTPase 1 3.06165
TMEM140 transmembrane protein 140 3.05155
TNIP1 TNFAIP3 interacting protein 1 3.0496
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 3.0459
PTPN12 protein tyrosine phosphatase, non-receptor type 12 3.03378
SLC35F2 solute carrier family 35, member F2 3.01665
PRAF2 PRA1 domain family, member 2 3.0093
MACF1 microtubule-actin crosslinking factor 1 2.97629
RALB v-ral simian leukemia viral oncogene homolog B 2.94167
LGALS4 lectin, galactoside-binding, soluble, 4 2.93915
ICAM1 intercellular adhesion molecule 1 2.93577
PADI1 peptidyl arginine deiminase, type I 2.91895
PDGFA platelet-derived growth factor alpha polypeptide 2.8954
IFI44L interferon-induced protein 44-like 2.8694
SSBP2 single-stranded DNA binding protein 2 2.85033
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.8384
NPC1 Niemann-Pick disease, type C1 2.82693
TBXAS1 thromboxane A synthase 1 (platelet) 2.8082
DUOX2 dual oxidase 2 2.7877
AARS1 alanyl-tRNA synthetase 1 2.7875
ZMIZ1 zinc finger, MIZ-type containing 1 2.7526
PFKL phosphofructokinase, liver 2.72505
ECD ecdysoneless homolog (Drosophila) 2.6815
MVP major vault protein 2.6637
CAB39 calcium binding protein 39 2.65145
SQOR sulfide quinone oxidoreductase 2.6402
CDK17 cyclin-dependent kinase 17 2.6396
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 2.63865
PMM2 phosphomannomutase 2 2.6061
TES testin LIM domain protein 2.58623
APOLD1 apolipoprotein L domain containing 1 2.56945
IGF2R insulin-like growth factor 2 receptor 2.5559
CLDN16 claudin 16 2.5322
PLSCR1 phospholipid scramblase 1 2.53163
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 2.526
GFPT1 glutamine--fructose-6-phosphate transaminase 1 2.52478
F2RL1 coagulation factor II (thrombin) receptor-like 1 2.5136
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.501
OXCT2 3-oxoacid CoA transferase 2 2.48
KDM6B lysine (K)-specific demethylase 6B 2.47895
NCSTN nicastrin 2.46885
RTP4 receptor (chemosensory) transporter protein 4 2.461
ZBTB20 zinc finger and BTB domain containing 20 2.45428
SMG5 SMG5 nonsense mediated mRNA decay factor 2.44158
NES nestin 2.43695
BTNL8 butyrophilin-like 8 2.4367
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 2.4287
FAM124B family with sequence similarity 124B 2.4284
TOMM34 translocase of outer mitochondrial membrane 34 2.4185
MUC13 mucin 13, cell surface associated 2.41315
CHMP1A charged multivesicular body protein 1A 2.40945
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.40803
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 2.4075
HS1BP3 HCLS1 binding protein 3 2.4023
CALU calumenin 2.4011
TJP2 tight junction protein 2 2.3956
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.38745
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 2.38065
IST1 increased sodium tolerance 1 homolog (yeast) 2.37875
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 2.3725
MBTPS1 membrane-bound transcription factor peptidase, site 1 2.36965
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.3681
PFDN2 prefoldin subunit 2 2.3629
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 2.36075
SMAD3 SMAD family member 3 2.35185
AADAC arylacetamide deacetylase 2.3478
CHN1 chimerin 1 2.3443
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial 2.34365
PBLD phenazine biosynthesis-like protein domain containing 2.3427
TBKBP1 TBK1 binding protein 1 2.33555
ATF6 activating transcription factor 6 2.3305
CFLAR CASP8 and FADD-like apoptosis regulator 2.31723
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.30428
DBN1 drebrin 1 2.29585
NBR1 neighbor of BRCA1 gene 1 2.28622
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 2.2779
RNF220 ring finger protein 220 2.27645
N4BP3 NEDD4 binding protein 3 2.27535
SCFD1 sec1 family domain containing 1 2.27055
ADGRG1 adhesion G protein-coupled receptor G1 2.27043
SDC4 syndecan 4 2.2641
SCRN1 secernin 1 2.25155
MMUT methylmalonyl-CoA mutase 2.24995
GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 2.2315
ETV7 ets variant 7 2.22745
HKDC1 hexokinase domain containing 1 2.22725
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2.22657
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 2.22333
MINK1 misshapen-like kinase 1 2.2223
GOLPH3 golgi phosphoprotein 3 (coat-protein) 2.22195
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 2.2184
FBXO7 F-box protein 7 2.2165
VNN2 vanin 2 2.21605
TRADD TNFRSF1A-associated via death domain 2.21035
MNT MAX network transcriptional repressor 2.2068
ARSL arylsulfatase L 2.2064
CES2 carboxylesterase 2 2.20555
ADAP2 ArfGAP with dual PH domains 2 2.2046
ALDOB aldolase B, fructose-bisphosphate 2.19546
WDTC1 WD and tetratricopeptide repeats 1 2.19502
RGPD2 RANBP2-like and GRIP domain containing 2 2.1918
ISG15 ISG15 ubiquitin-like modifier 2.1877
ZBTB22 zinc finger and BTB domain containing 22 2.1876
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 2.1863
CREB5 cAMP responsive element binding protein 5 2.1856
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.18285
PAMR1 peptidase domain containing associated with muscle regeneration 1 2.1817
ZNF282 zinc finger protein 282 2.18
CSNK1A1 casein kinase 1, alpha 1 2.17668
MUC4 mucin 4, cell surface associated 2.17613
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 2.17235
F2R coagulation factor II (thrombin) receptor 2.17235
LOC107987462 leukocyte immunoglobulin-like receptor subfamily B member 3 2.16121
ZMYM2 zinc finger, MYM-type 2 2.15768
MMRN1 multimerin 1 2.14145
DEFA6 defensin, alpha 6, Paneth cell-specific 2.1392
VWA1 von Willebrand factor A domain containing 1 2.1386
MRPS18B mitochondrial ribosomal protein S18B 2.13742
GAL3ST4 galactose-3-O-sulfotransferase 4 2.13315
IFI44 interferon-induced protein 44 2.1317
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 2.1299
VNN1 vanin 1 2.1247
RXRG retinoid X receptor, gamma 2.1246
KLF9 Kruppel-like factor 9 2.1227
LAX1 lymphocyte transmembrane adaptor 1 2.12025
ARMCX3 armadillo repeat containing, X-linked 3 2.11955
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 2.11845
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.1123
GPR19 G protein-coupled receptor 19 2.10645
VSIG4 V-set and immunoglobulin domain containing 4 2.1038
ADAT1 adenosine deaminase, tRNA-specific 1 2.1031
PELI2 pellino E3 ubiquitin protein ligase family member 2 2.09485
JAM3 junctional adhesion molecule 3 2.0947
NECTIN4 nectin cell adhesion molecule 4 2.09295
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.092
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 2.0915
MEF2D myocyte enhancer factor 2D 2.0902
CA6 carbonic anhydrase VI 2.08805
TERF2IP telomeric repeat binding factor 2, interacting protein 2.0879
ASMTL acetylserotonin O-methyltransferase-like 2.08645
RSAD2 radical S-adenosyl methionine domain containing 2 2.0853
PHF20L1 PHD finger protein 20-like 1 2.0845
PTK2 protein tyrosine kinase 2 2.08348
KDM5A lysine (K)-specific demethylase 5A 2.08235
SEC24C SEC24 family member C 2.08165
DOK5 docking protein 5 2.08025
S1PR1 sphingosine-1-phosphate receptor 1 2.0783
MT1F metallothionein 1F 2.07805
IL36A interleukin 36, alpha 2.07635
LONRF3 LON peptidase N-terminal domain and ring finger 3 2.06815
SLCO4A1 solute carrier organic anion transporter family, member 4A1 2.06505
ATOSB atos homolog B 2.06503
NARS1 asparaginyl-tRNA synthetase 1 2.0638
RNF103-CHMP3 RNF103-CHMP3 readthrough 2.05945
GMPPA GDP-mannose pyrophosphorylase A 2.059
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 2.05785
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 2.05725
SEPSECS Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase 2.05708
NR1I2 nuclear receptor subfamily 1, group I, member 2 2.0556
FLNC filamin C, gamma 2.0519
KIF13B kinesin family member 13B 2.0441
ACTN4 actinin, alpha 4 2.03965
TUT7 terminal uridylyl transferase 7 2.02935
ERN1 endoplasmic reticulum to nucleus signaling 1 2.02895
ZNF358 zinc finger protein 358 2.02685
HSPB2 heat shock 27kDa protein 2 2.0259
HPSE heparanase 2.02405
AXIN1 axin 1 2.0223
TM4SF20 transmembrane 4 L six family member 20 2.02065
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 2.0204
REC8 REC8 meiotic recombination protein 2.02035
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.01705
CD7 CD7 molecule 2.01657
APLNR apelin receptor 2.0156
ZBTB35 zinc finger and BTB domain containing 35 2.00863
MMD monocyte to macrophage differentiation-associated 2.0085
CAPNS1 calpain, small subunit 1 2.00405
EPHA2 EPH receptor A2 2.0035
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 2.00217

decreased expression

Symbol Name Standardized Value
TRIB3 tribbles pseudokinase 3 -10.0
CDC20 cell division cycle 20 -8.60725
TARBP1 TAR (HIV-1) RNA binding protein 1 -6.99265
COG7 component of oligomeric golgi complex 7 -6.9911
AURKB aurora kinase B -6.96475
TCTN1 tectonic family member 1 -6.9201
ZW10 zw10 kinetochore protein -6.86075
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -6.57085
ISOC1 isochorismatase domain containing 1 -6.12
ICAM3 intercellular adhesion molecule 3 -6.0525
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -5.9016
CDC25B cell division cycle 25B -5.90055
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -5.71125
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -5.6202
CCNB2 cyclin B2 -5.4254
PGM1 phosphoglucomutase 1 -5.4243
ACAA1 acetyl-CoA acyltransferase 1 -5.3081
PLK1 polo-like kinase 1 -5.0787
REEP5 receptor accessory protein 5 -5.05317
LDHD lactate dehydrogenase D -5.0297
ALDOC aldolase C, fructose-bisphosphate -4.92245
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -4.87305
MELK maternal embryonic leucine zipper kinase -4.84055
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -4.78127
NUP85 nucleoporin 85kDa -4.7441
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.6992
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -4.6878
IDI1 isopentenyl-diphosphate delta isomerase 1 -4.46163
CHEK1 checkpoint kinase 1 -4.45125
STMN1 stathmin 1 -4.3684
NLRP2B NLR family pyrin domain containing 2B -4.3413
ELAC2 elaC ribonuclease Z 2 -4.3334
AZGP1 alpha-2-glycoprotein 1, zinc-binding -4.29537
USP6NL USP6 N-terminal like -4.2912
PSRC1 proline/serine-rich coiled-coil 1 -4.1152
DDB2 damage-specific DNA binding protein 2, 48kDa -4.04035
HSPB1 heat shock 27kDa protein 1 -4.03875
MCM10 minichromosome maintenance complex component 10 -4.01575
PDZD2 PDZ domain containing 2 -3.98612
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -3.96225
SOAT2 sterol O-acyltransferase 2 -3.86985
CCNA2 cyclin A2 -3.76468
PGAM4 phosphoglycerate mutase family member 4 -3.66285
BIRC5 baculoviral IAP repeat containing 5 -3.64683
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -3.61995
RBM15B RNA binding motif protein 15B -3.5518
NT5DC2 5'-nucleotidase domain containing 2 -3.54245
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -3.53355
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.48795
THAP11 THAP domain containing 11 -3.3992
WRAP53 WD repeat containing, antisense to TP53 -3.3879
B4GAT1 beta-1,4-glucuronyltransferase 1 -3.3259
CD58 CD58 molecule -3.27823
CDK1 cyclin-dependent kinase 1 -3.22748
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -3.22025
ERCC6L excision repair cross-complementation group 6-like -3.2175
KIF18A kinesin family member 18A -3.20305
DERA deoxyribose-phosphate aldolase (putative) -3.1855
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -3.1795
DSCC1 DNA replication and sister chromatid cohesion 1 -3.1641
HEBP1 heme binding protein 1 -3.1436
MAPK13 mitogen-activated protein kinase 13 -3.14247
AUNIP aurora kinase A and ninein interacting protein -3.13165
TEDC2 tubulin epsilon and delta complex 2 -3.07595
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.06615
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -3.0568
FASTKD5 FAST kinase domains 5 -3.0295
HAT1 histone acetyltransferase 1 -3.0095
HSPA8 heat shock 70kDa protein 8 -3.00915
FAM234B family with sequence similarity 234 member B -3.00845
CDCA8 cell division cycle associated 8 -2.9622
HSPA1A heat shock 70kDa protein 1A -2.9361
GPER1 G protein-coupled estrogen receptor 1 -2.93148
ADI1 acireductone dioxygenase 1 -2.8952
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -2.87733
RIOX1 ribosomal oxygenase 1 -2.87125
PAGR1 PAXIP1 associated glutamate-rich protein 1 -2.82555
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.7946
NCAPH non-SMC condensin I complex, subunit H -2.7805
RMI1 RecQ mediated genome instability 1 -2.77795
SESN1 sestrin 1 -2.7657
CCNB1 cyclin B1 -2.7529
RABL6 RAB, member RAS oncogene family-like 6 -2.7485
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.73795
TOP2A topoisomerase (DNA) II alpha 170kDa -2.73333
CEP76 centrosomal protein 76kDa -2.72275
MAPK9 mitogen-activated protein kinase 9 -2.71502
ELP5 elongator acetyltransferase complex subunit 5 -2.7067
WDCP WD repeat and coiled coil containing -2.7007
RECQL4 RecQ protein-like 4 -2.692
MSH2 mutS homolog 2 -2.68755
PGRMC1 progesterone receptor membrane component 1 -2.67898
DHCR7 7-dehydrocholesterol reductase -2.66873
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8 -2.66335
TRAPPC4 trafficking protein particle complex 4 -2.63512
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.63312
GMNN geminin, DNA replication inhibitor -2.6206
MSMO1 methylsterol monooxygenase 1 -2.6139
HMGB3 high mobility group box 3 -2.60465
ASF1B anti-silencing function 1B histone chaperone -2.6044
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.5934
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -2.5796
ZDHHC6 zinc finger, DHHC-type containing 6 -2.5693
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.5683
YAF2 YY1 associated factor 2 -2.5438
POLR1A polymerase (RNA) I polypeptide A, 194kDa -2.53362
WASF1 WAS protein family, member 1 -2.50195
ORC3 origin recognition complex, subunit 3 -2.5007
NUCB2 nucleobindin 2 -2.4905
TRAP1 TNF receptor-associated protein 1 -2.47955
KLHDC2 kelch domain containing 2 -2.47465
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -2.46755
MSH6 mutS homolog 6 -2.45675
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.4546
RPUSD2 RNA pseudouridylate synthase domain containing 2 -2.44295
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.4373
HADH hydroxyacyl-CoA dehydrogenase -2.43647
PMCH pro-melanin-concentrating hormone -2.42305
RNF139 ring finger protein 139 -2.4164
BCL7C B-cell CLL/lymphoma 7C -2.41375
KIF11 kinesin family member 11 -2.4068
TARBP2 TAR (HIV-1) RNA binding protein 2 -2.4016
DHRS2 dehydrogenase/reductase (SDR family) member 2 -2.40158
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) -2.39925
YEATS4 YEATS domain containing 4 -2.3978
NVL nuclear VCP-like -2.3976
NUP107 nucleoporin 107kDa -2.3918
SPDL1 spindle apparatus coiled-coil protein 1 -2.38955
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme -2.36262
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.36085
TMEM97 transmembrane protein 97 -2.3603
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.35475
CDCA3 cell division cycle associated 3 -2.35045
IRX5 iroquois homeobox 5 -2.33395
GSTM2 glutathione S-transferase mu 2 (muscle) -2.31925
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.31835
JMJD4 jumonji domain containing 4 -2.3112
TBC1D10C TBC1 domain family, member 10C -2.3044
DCK deoxycytidine kinase -2.30125
ZNF202 zinc finger protein 202 -2.29958
CCNF cyclin F -2.28828
TM7SF3 transmembrane 7 superfamily member 3 -2.2851
NRIP1 nuclear receptor interacting protein 1 -2.2733
TMCO1 transmembrane and coiled-coil domains 1 -2.2699
FANCI Fanconi anemia, complementation group I -2.26115
XPO1 exportin 1 -2.26085
CASP3 caspase 3, apoptosis-related cysteine peptidase -2.2602
SCUBE2 signal peptide, CUB domain, EGF-like 2 -2.2534
TCEA2 transcription elongation factor A (SII), 2 -2.2363
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) -2.2311
TK1 thymidine kinase 1, soluble -2.1912
RWDD3 RWD domain containing 3 -2.191
CCDC15 coiled-coil domain containing 15 -2.1891
TSEN2 TSEN2 tRNA splicing endonuclease subunit -2.1801
NCAPD3 non-SMC condensin II complex, subunit D3 -2.1772
PGAP2 post-GPI attachment to proteins 2 -2.17225
SMIM29 small integral membrane protein 29 -2.1679
PGP phosphoglycolate phosphatase -2.16675
LIN7B lin-7 homolog B (C. elegans) -2.1571
AMDHD2 amidohydrolase domain containing 2 -2.1569
CHAD chondroadherin -2.1516
ECH1 enoyl CoA hydratase 1, peroxisomal -2.15095
OIP5 Opa interacting protein 5 -2.15025
CKAP5 cytoskeleton associated protein 5 -2.1484
ICMT isoprenylcysteine carboxyl methyltransferase -2.1422
TIPIN TIMELESS interacting protein -2.14105
TXNDC9 thioredoxin domain containing 9 -2.13917
DBF4 DBF4 zinc finger -2.1342
CDK4 cyclin-dependent kinase 4 -2.1295
TCERG1 transcription elongation regulator 1 -2.12635
RFC5 replication factor C (activator 1) 5, 36.5kDa -2.12085
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 -2.1186
SUGCT succinyl-CoA:glutarate-CoA transferase -2.11835
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.11585
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.1158
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa -2.1156
SRPK3 SRSF protein kinase 3 -2.10995
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) -2.1097
FEN1 flap structure-specific endonuclease 1 -2.1042
NEK4 NIMA-related kinase 4 -2.09925
ZNF274 zinc finger protein 274 -2.09465
PUF60 poly-U binding splicing factor 60KDa -2.0929
MLEC malectin -2.08312
CLCN6 chloride channel, voltage-sensitive 6 -2.0808
SMCO4 single-pass membrane protein with coiled-coil domains 4 -2.07735
NR1H3 nuclear receptor subfamily 1, group H, member 3 -2.07565
FBXO5 F-box protein 5 -2.07255
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.0661
VRK1 vaccinia related kinase 1 -2.06035
STIMATE STIM activating enhancer -2.0602
PYCR3 pyrroline-5-carboxylate reductase 3 -2.0587
SAC3D1 SAC3 domain containing 1 -2.0543
PEX11A peroxisomal biogenesis factor 11 alpha -2.0539
DCP2 decapping mRNA 2 -2.05065
SIX1 SIX homeobox 1 -2.04555
ZNF473 zinc finger protein 473 -2.04243
LRRC42 leucine rich repeat containing 42 -2.04025
FBXL6 F-box and leucine-rich repeat protein 6 -2.03845
CHIC2 cysteine-rich hydrophobic domain 2 -2.0361
DOC2B double C2-like domains, beta -2.0357
CDC6 cell division cycle 6 -2.0341
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -2.03025
KIF22 kinesin family member 22 -2.02908
FXYD6-FXYD2 FXYD6-FXYD2 readthrough -2.02865
MANF mesencephalic astrocyte-derived neurotrophic factor -2.01955
ATF5 activating transcription factor 5 -2.01898
PTHLH parathyroid hormone-like hormone -2.01643
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.01405
WASHC4 WASH complex subunit 4 -2.01103
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -2.01085
TRIP13 thyroid hormone receptor interactor 13 -2.00795