| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tiabendazole 20.1 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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167 genes differentially expressed following the CRCGN008_HEPG2_24H:H08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABHD6 | abhydrolase domain containing 6 | 9.18872 |
| UBQLN2 | ubiquilin 2 | 5.4454 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.3822 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 5.30605 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 5.23135 |
| PLS1 | plastin 1 | 5.22915 |
| MCOLN1 | mucolipin 1 | 5.07585 |
| ATP11B | ATPase, class VI, type 11B | 4.9701 |
| PRR15L | proline rich 15-like | 4.8966 |
| STK10 | serine/threonine kinase 10 | 4.85207 |
| E2F2 | E2F transcription factor 2 | 4.70575 |
| MSRA | methionine sulfoxide reductase A | 4.67545 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 4.50007 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.21685 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 4.02085 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.84083 |
| MCM3 | minichromosome maintenance complex component 3 | 3.8242 |
| FPGS | folylpolyglutamate synthase | 3.7732 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 3.7706 |
| NOTCH1 | notch 1 | 3.5408 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 3.4796 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 3.40983 |
| STIMATE | STIM activating enhancer | 3.3477 |
| CHMP6 | charged multivesicular body protein 6 | 3.2663 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 3.02597 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.99395 |
| PLSCR1 | phospholipid scramblase 1 | 2.9155 |
| JADE2 | jade family PHD finger 2 | 2.78568 |
| EXOC3 | exocyst complex component 3 | 2.73375 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 2.722 |
| DYSF | dysferlin | 2.666 |
| CDC45 | cell division cycle 45 | 2.6063 |
| EPHA3 | EPH receptor A3 | 2.54445 |
| NKX2-2 | NK2 homeobox 2 | 2.53195 |
| NAPSA | napsin A aspartic peptidase | 2.5198 |
| KLHL9 | kelch-like family member 9 | 2.50605 |
| METRN | meteorin, glial cell differentiation regulator | 2.4779 |
| CCNA1 | cyclin A1 | 2.46225 |
| MAP7 | microtubule-associated protein 7 | 2.45907 |
| ARMCX5 | armadillo repeat containing, X-linked 5 | 2.4501 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) | 2.44995 |
| GTF2H4 | general transcription factor IIH, polypeptide 4, 52kDa | 2.4456 |
| MTMR14 | myotubularin related protein 14 | 2.42415 |
| TSPYL4 | TSPY-like 4 | 2.4148 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 2.39995 |
| MSN | moesin | 2.3807 |
| SHB | Src homology 2 domain containing adaptor protein B | 2.37283 |
| CYCS | cytochrome c, somatic | 2.37085 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | 2.3546 |
| TM2D3 | TM2 domain containing 3 | 2.29 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 2.2712 |
| MCM9 | minichromosome maintenance complex component 9 | 2.26235 |
| SAP30BP | SAP30 binding protein | 2.2608 |
| ACSM2A | acyl-CoA synthetase medium-chain family member 2A | 2.2478 |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) | 2.238 |
| PNPLA6 | patatin-like phospholipase domain containing 6 | 2.20625 |
| TMEM115 | transmembrane protein 115 | 2.1744 |
| RIN3 | Ras and Rab interactor 3 | 2.1683 |
| ARHGAP10 | Rho GTPase activating protein 10 | 2.16645 |
| RTL8A | retrotransposon Gag like 8A | 2.1613 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) | 2.1406 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase | 2.1396 |
| SASH1 | SAM and SH3 domain containing 1 | 2.1388 |
| CASKIN2 | CASK interacting protein 2 | 2.13543 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | 2.13485 |
| RLN2 | relaxin 2 | 2.1331 |
| OCRL | oculocerebrorenal syndrome of Lowe | 2.1199 |
| BEX4 | brain expressed, X-linked 4 | 2.11585 |
| GMPPB | GDP-mannose pyrophosphorylase B | 2.1152 |
| USP6NL | USP6 N-terminal like | 2.1051 |
| CRTAP | cartilage associated protein | 2.10265 |
| SALL2 | spalt-like transcription factor 2 | 2.10005 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 2.08623 |
| ITPRID2 | ITPR interacting domain containing 2 | 2.0855 |
| AXIN1 | axin 1 | 2.0849 |
| DDA1 | DET1 and DDB1 associated 1 | 2.0585 |
| NPY1R | neuropeptide Y receptor Y1 | 2.0553 |
| APOD | apolipoprotein D | 2.05425 |
| INSM1 | insulinoma-associated 1 | 2.0472 |
| CREB1 | cAMP responsive element binding protein 1 | 2.0459 |
| SCRN1 | secernin 1 | 2.0455 |
| REXO4 | REX4, RNA exonuclease 4 homolog (S. cerevisiae) | 2.03875 |
| RAB3A | RAB3A, member RAS oncogene family | 2.03595 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 2.02406 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 2.01625 |
| CALCB | calcitonin-related polypeptide beta | 2.0146 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | 2.01085 |
| RPL36A | ribosomal protein L36a | 2.008 |
| HOOK1 | hook microtubule-tethering protein 1 | 2.00125 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -10.0 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -6.08075 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -5.76535 |
| ZNF586 | zinc finger protein 586 | -5.21965 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -5.19855 |
| STAMBP | STAM binding protein | -5.1187 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.89755 |
| PCNA | proliferating cell nuclear antigen | -4.77245 |
| CCNB1 | cyclin B1 | -4.63945 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -4.4243 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.3025 |
| RPN1 | ribophorin I | -4.2873 |
| FASTKD5 | FAST kinase domains 5 | -4.11955 |
| HSPB1 | heat shock 27kDa protein 1 | -3.61865 |
| MMP24-AS1-EDEM2 | MMP24-AS1-EDEM2 readthrough | -3.2776 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -3.1077 |
| SMYD2 | SET and MYND domain containing 2 | -3.066 |
| TMEM109 | transmembrane protein 109 | -2.8586 |
| AURKB | aurora kinase B | -2.7142 |
| NEK7 | NIMA-related kinase 7 | -2.57405 |
| HSPA8 | heat shock 70kDa protein 8 | -2.57225 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -2.5173 |
| RNFT1-DT | RNFT1 divergent transcript | -2.51515 |
| PTGES | prostaglandin E synthase | -2.42622 |
| RBBP7 | retinoblastoma binding protein 7 | -2.41345 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -2.3889 |
| SOD1 | superoxide dismutase 1, soluble | -2.38835 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | -2.38305 |
| LOC124907837 | sulfotransferase 1A3 | -2.35391 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.3321 |
| PRCC | papillary renal cell carcinoma (translocation-associated) | -2.3197 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 | -2.30948 |
| KLHL3 | kelch-like family member 3 | -2.3086 |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 | -2.3073 |
| RGS2 | regulator of G-protein signaling 2 | -2.28095 |
| GNAS | GNAS complex locus | -2.27576 |
| CD53 | CD53 molecule | -2.258 |
| ZNF26 | zinc finger protein 26 | -2.25155 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.24558 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | -2.24182 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit | -2.24123 |
| WDR26 | WD repeat domain 26 | -2.22755 |
| TMEM50A | transmembrane protein 50A | -2.219 |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) | -2.2143 |
| ZNF154 | zinc finger protein 154 | -2.2108 |
| CATSPER2 | cation channel, sperm associated 2 | -2.2103 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -2.19945 |
| LAX1 | lymphocyte transmembrane adaptor 1 | -2.1923 |
| ENAH | enabled homolog (Drosophila) | -2.18705 |
| PRKD3 | protein kinase D3 | -2.1788 |
| PARK7 | parkinson protein 7 | -2.1731 |
| OFD1 | oral-facial-digital syndrome 1 | -2.16725 |
| FASTKD1 | FAST kinase domains 1 | -2.1453 |
| TRMT61B | tRNA methyltransferase 61B | -2.1427 |
| CD163L1 | CD163 molecule-like 1 | -2.13625 |
| PLA2G15 | phospholipase A2, group XV | -2.1333 |
| TSNAX | translin-associated factor X | -2.13105 |
| EIF2B1 | eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa | -2.1296 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -2.11075 |
| HMBOX1 | homeobox containing 1 | -2.10895 |
| LHX1 | LIM homeobox 1 | -2.1054 |
| TSPAN7 | tetraspanin 7 | -2.0993 |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G | -2.09015 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.0858 |
| CRYZL1 | crystallin, zeta (quinone reductase)-like 1 | -2.0791 |
| PNRC2 | proline-rich nuclear receptor coactivator 2 | -2.07535 |
| ATRAID | all-trans retinoic acid-induced differentiation factor | -2.0528 |
| PTX3 | pentraxin 3, long | -2.052 |
| CD46 | CD46 molecule, complement regulatory protein | -2.04695 |
| COPG1 | coatomer protein complex, subunit gamma 1 | -2.0424 |
| RANBP9 | RAN binding protein 9 | -2.03155 |
| AK5 | adenylate kinase 5 | -2.0308 |
| ANKMY2 | ankyrin repeat and MYND domain containing 2 | -2.01995 |
| ZNF281 | zinc finger protein 281 | -2.013 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -2.0088 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | -2.0063 |
| MARCHF5 | membrane associated ring-CH-type finger 5 | -2.0055 |
| ZRSR2 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 | -2.00535 |
