CRCGN008_HEPG2_24H:H10 Gene Set
Genes
50 genes differentially expressed following the CRCGN008_HEPG2_24H:H10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
10.0
|
|
UBQLN2
|
ubiquilin 2
|
5.2879
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
5.26555
|
|
SQOR
|
sulfide quinone oxidoreductase
|
5.2581
|
|
MAMLD1
|
mastermind-like domain containing 1
|
5.2064
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.07095
|
|
ABHD6
|
abhydrolase domain containing 6
|
5.03503
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
4.7734
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.6269
|
|
CCDC92
|
coiled-coil domain containing 92
|
4.5253
|
|
NOTCH1
|
notch 1
|
4.36635
|
|
SATB1
|
SATB homeobox 1
|
4.1638
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.71378
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.63333
|
|
PLSCR1
|
phospholipid scramblase 1
|
3.1053
|
|
SFTPB
|
surfactant protein B
|
2.97688
|
|
MAP7
|
microtubule-associated protein 7
|
2.912
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.72918
|
|
SPTAN1
|
spectrin, alpha, non-erythrocytic 1
|
2.6059
|
|
RAB11FIP2
|
RAB11 family interacting protein 2 (class I)
|
2.56693
|
|
CYCS
|
cytochrome c, somatic
|
2.3086
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.2157
|
|
TBP
|
TATA box binding protein
|
2.2082
|
|
ZBTB35
|
zinc finger and BTB domain containing 35
|
2.19488
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
2.1925
|
|
CDK4
|
cyclin-dependent kinase 4
|
2.0886
|
|
CEMIP
|
cell migration inducing protein, hyaluronan binding
|
2.0229
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-5.0619
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-5.0
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.77245
|
|
CCNB2
|
cyclin B2
|
-4.70205
|
|
CDC20
|
cell division cycle 20
|
-4.6933
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.57815
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.92595
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.91925
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.3349
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.11757
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-2.93235
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.88215
|
|
CCNB1
|
cyclin B1
|
-2.72235
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
-2.70835
|
|
CDC25B
|
cell division cycle 25B
|
-2.6995
|
|
JAM3
|
junctional adhesion molecule 3
|
-2.25645
|
|
P3H3
|
prolyl 3-hydroxylase 3
|
-2.23695
|
|
PFKFB3
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
|
-2.0958
|
|
TSPAN3
|
tetraspanin 3
|
-2.05608
|
|
CYRIA
|
CYFIP related Rac1 interactor A
|
-2.03608
|
|
NVL
|
nuclear VCP-like
|
-2.02715
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
-2.02165
|
