| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tiabendazole 2.51 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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79 genes differentially expressed following the CRCGN008_HEPG2_24H:H11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PRR15L | proline rich 15-like | 8.0778 |
| GSTZ1 | glutathione S-transferase zeta 1 | 5.13725 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.92995 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 4.92315 |
| EGF | epidermal growth factor | 4.7851 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.66995 |
| LCN2 | lipocalin 2 | 4.66275 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.6585 |
| CBR3 | carbonyl reductase 3 | 4.46715 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 4.4334 |
| UBQLN2 | ubiquilin 2 | 4.3689 |
| STK10 | serine/threonine kinase 10 | 4.20127 |
| ARL4C | ADP-ribosylation factor-like 4C | 4.07897 |
| EPN2 | epsin 2 | 4.0574 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 4.03738 |
| SKIC2 | SKI2 subunit of superkiller complex | 3.4023 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.10105 |
| PTK2 | protein tyrosine kinase 2 | 3.0704 |
| KIF20A | kinesin family member 20A | 2.72465 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 2.68685 |
| MTERF3 | mitochondrial transcription termination factor 3 | 2.6572 |
| RNF123 | ring finger protein 123 | 2.64395 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.6174 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.58265 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 2.4296 |
| YPEL1 | yippee-like 1 (Drosophila) | 2.4159 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.4151 |
| TLK2 | tousled-like kinase 2 | 2.41252 |
| SYNGR2 | synaptogyrin 2 | 2.2908 |
| LAS1L | LAS1-like (S. cerevisiae) | 2.24585 |
| STXBP2 | syntaxin binding protein 2 | 2.22135 |
| ERI2 | ERI1 exoribonuclease family member 2 | 2.12395 |
| RAB5B | RAB5B, member RAS oncogene family | 2.10145 |
| IVD | isovaleryl-CoA dehydrogenase | 2.0935 |
| DHRS7B | dehydrogenase/reductase (SDR family) member 7B | 2.09025 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 2.05035 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | 2.0447 |
| TRIM24 | tripartite motif containing 24 | 2.04392 |
| UCMA | upper zone of growth plate and cartilage matrix associated | 2.02435 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 2.00725 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -10.0 |
| LDHD | lactate dehydrogenase D | -10.0 |
| ZNF586 | zinc finger protein 586 | -5.91055 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -5.2562 |
| TLCD3A | TLC domain containing 3A | -5.1873 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -4.9319 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -4.85895 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.7659 |
| FAIM | Fas apoptotic inhibitory molecule | -4.6633 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -4.3225 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.98335 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.86917 |
| VDAC1 | voltage-dependent anion channel 1 | -3.86783 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.5696 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.3786 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.36715 |
| SPAG4 | sperm associated antigen 4 | -3.182 |
| CDC25B | cell division cycle 25B | -3.0774 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.851 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.7751 |
| RNF167 | ring finger protein 167 | -2.7358 |
| PROS1 | protein S (alpha) | -2.6829 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.63355 |
| GLOD4 | glyoxalase domain containing 4 | -2.58425 |
| AK4 | adenylate kinase 4 | -2.50577 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.4148 |
| RBM34 | RNA binding motif protein 34 | -2.40615 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -2.40465 |
| HSPA8 | heat shock 70kDa protein 8 | -2.36528 |
| PLXDC2 | plexin domain containing 2 | -2.2985 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | -2.29263 |
| TMEM230 | transmembrane protein 230 | -2.2637 |
| VWF | von Willebrand factor | -2.1303 |
| STMN1 | stathmin 1 | -2.0962 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | -2.07 |
| RINT1 | RAD50 interactor 1 | -2.0403 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -2.02765 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -2.0175 |
| SULT1C4 | sulfotransferase family, cytosolic, 1C, member 4 | -2.01067 |
