| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | (2s)-2-amino-4-(ethylsulfanyl)butanoic acid 2.68 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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52 genes differentially expressed following the CRCGN008_HEPG2_24H:H16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STK10 | serine/threonine kinase 10 | 5.46495 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.37865 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 4.6146 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 3.91055 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.83242 |
| ABHD6 | abhydrolase domain containing 6 | 3.48417 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.2563 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 2.83575 |
| CYCS | cytochrome c, somatic | 2.6633 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.63315 |
| HEBP1 | heme binding protein 1 | 2.5956 |
| RALGDS | ral guanine nucleotide dissociation stimulator | 2.5738 |
| RNF11 | ring finger protein 11 | 2.48195 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 2.4213 |
| BZW2 | basic leucine zipper and W2 domains 2 | 2.26185 |
| GATA2 | GATA binding protein 2 | 2.25183 |
| METRN | meteorin, glial cell differentiation regulator | 2.25015 |
| RBM34 | RNA binding motif protein 34 | 2.19605 |
| MCM3 | minichromosome maintenance complex component 3 | 2.0857 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A | 2.0229 |
| RAI14 | retinoic acid induced 14 | 2.00475 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -7.5643 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -7.4595 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -5.85495 |
| TRIB3 | tribbles pseudokinase 3 | -5.20235 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -5.1006 |
| CHMP4B | charged multivesicular body protein 4B | -4.98802 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -4.8315 |
| CCNB2 | cyclin B2 | -4.70205 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.57815 |
| MRPS16 | mitochondrial ribosomal protein S16 | -4.54115 |
| HAT1 | histone acetyltransferase 1 | -4.4214 |
| MAPK13 | mitogen-activated protein kinase 13 | -4.23168 |
| GNAS | GNAS complex locus | -3.79424 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.73233 |
| PRPF4 | pre-mRNA processing factor 4 | -3.54128 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.2385 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -3.20165 |
| REEP5 | receptor accessory protein 5 | -2.7391 |
| SLC35F2 | solute carrier family 35, member F2 | -2.7215 |
| MICU1 | mitochondrial calcium uptake 1 | -2.40335 |
| INSIG1 | insulin induced gene 1 | -2.31032 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.306 |
| CEP112 | centrosomal protein 112kDa | -2.30365 |
| PAX9 | paired box 9 | -2.27025 |
| SLC25A16 | solute carrier family 25 (mitochondrial carrier), member 16 | -2.18715 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | -2.1736 |
| SIRT1 | sirtuin 1 | -2.1533 |
| HNMT | histamine N-methyltransferase | -2.0712 |
| ANXA11 | annexin A11 | -2.04607 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.01925 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | -2.00595 |
