| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | (2s)-2-amino-4-(ethylsulfanyl)butanoic acid 1.34 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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80 genes differentially expressed following the CRCGN008_HEPG2_24H:H17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHN1 | chimerin 1 | 6.13475 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 5.53285 |
| ZNF589 | zinc finger protein 589 | 5.33665 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.17365 |
| ADRB2 | adrenoceptor beta 2, surface | 5.11225 |
| MAMLD1 | mastermind-like domain containing 1 | 5.0 |
| CBR3 | carbonyl reductase 3 | 4.7909 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 4.66065 |
| NOTCH1 | notch 1 | 4.55135 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 4.41065 |
| MYLK | myosin light chain kinase | 4.3433 |
| PLSCR3 | phospholipid scramblase 3 | 3.85563 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.73505 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 3.6271 |
| GATA3 | GATA binding protein 3 | 3.4498 |
| ABHD6 | abhydrolase domain containing 6 | 3.40888 |
| PLSCR1 | phospholipid scramblase 1 | 3.40747 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 3.3645 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 3.029 |
| METRN | meteorin, glial cell differentiation regulator | 3.0012 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.63322 |
| GATA2 | GATA binding protein 2 | 2.58015 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | 2.5381 |
| CYCS | cytochrome c, somatic | 2.52565 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 2.51115 |
| JCHAIN | joining chain of multimeric IgA and IgM | 2.29745 |
| LPL | lipoprotein lipase | 2.2883 |
| EHD4 | EH-domain containing 4 | 2.21795 |
| PFDN2 | prefoldin subunit 2 | 2.16585 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.1474 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 2.12868 |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | 2.10847 |
| PJA1 | praja ring finger 1, E3 ubiquitin protein ligase | 2.0747 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.05285 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 2.05263 |
| HYOU1 | hypoxia up-regulated 1 | 2.0357 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 2.0204 |
| ITGB7 | integrin, beta 7 | 2.01895 |
| PDE8B | phosphodiesterase 8B | 2.00745 |
| GPM6B | glycoprotein M6B | 2.0063 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -10.0 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -5.8334 |
| NUP85 | nucleoporin 85kDa | -5.2349 |
| FASTKD5 | FAST kinase domains 5 | -5.2197 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -4.9429 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -4.83885 |
| PCNA | proliferating cell nuclear antigen | -4.81965 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -4.5233 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -4.0977 |
| CCNB2 | cyclin B2 | -3.8922 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.8421 |
| WASHC4 | WASH complex subunit 4 | -3.54658 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.24868 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.9849 |
| HSPA8 | heat shock 70kDa protein 8 | -2.8945 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -2.85745 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.73645 |
| SNX11 | sorting nexin 11 | -2.73417 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | -2.5196 |
| E2F8 | E2F transcription factor 8 | -2.48365 |
| MLH1 | mutL homolog 1 | -2.46685 |
| TXNDC9 | thioredoxin domain containing 9 | -2.36735 |
| ZW10 | zw10 kinetochore protein | -2.253 |
| RPL37 | ribosomal protein L37 | -2.24005 |
| MED17 | mediator complex subunit 17 | -2.20245 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -2.1871 |
| EXOSC10 | exosome component 10 | -2.1549 |
| TOPBP1 | topoisomerase (DNA) II binding protein 1 | -2.1307 |
| DTD1 | D-tyrosyl-tRNA deacylase 1 | -2.11245 |
| MRPS7 | mitochondrial ribosomal protein S7 | -2.08885 |
| GATA4 | GATA binding protein 4 | -2.0813 |
| PSPC1 | paraspeckle component 1 | -2.07985 |
| LIPC | lipase, hepatic | -2.0798 |
| PANX1 | pannexin 1 | -2.0797 |
| SUMO4 | small ubiquitin-like modifier 4 | -2.0672 |
| ALKBH1 | alkB, alkylation repair homolog 1 (E. coli) | -2.05945 |
| RFK | riboflavin kinase | -2.0345 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -2.02255 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.0219 |
| ADAM2 | ADAM metallopeptidase domain 2 | -2.01825 |
