CRCGN008_HEPG2_24H:I01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methotrexate 20.68 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

394 genes differentially expressed following the CRCGN008_HEPG2_24H:I01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
KIFBP kinesin family binding protein 7.8678
CNPY3 canopy FGF signaling regulator 3 7.64885
INPP1 inositol polyphosphate-1-phosphatase 7.5704
TIMP2 TIMP metallopeptidase inhibitor 2 6.8773
IER3 immediate early response 3 6.7102
NPDC1 neural proliferation, differentiation and control, 1 5.90365
ADGRE5 adhesion G protein-coupled receptor E5 5.85015
IGFBP3 insulin-like growth factor binding protein 3 5.4281
S100A4 S100 calcium binding protein A4 5.2056
TUBB6 tubulin, beta 6 class V 5.1888
ADRB2 adrenoceptor beta 2, surface 5.0343
CCL2 chemokine (C-C motif) ligand 2 4.8852
GLRX glutaredoxin (thioltransferase) 4.79037
TAC4 tachykinin 4 (hemokinin) 4.7626
MVP major vault protein 4.6464
SPAG7 sperm associated antigen 7 4.498
ACOT9 acyl-CoA thioesterase 9 4.48955
EGF epidermal growth factor 4.41085
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 4.3117
CCP110 centriolar coiled coil protein 110kDa 4.29565
LGALS8 lectin, galactoside-binding, soluble, 8 4.27832
CHN1 chimerin 1 4.19655
DUSP6 dual specificity phosphatase 6 4.1247
EPHA3 EPH receptor A3 4.08282
NPC1 Niemann-Pick disease, type C1 4.03657
PKN1 protein kinase N1 3.82183
DDB2 damage-specific DNA binding protein 2, 48kDa 3.75395
LAP3 leucine aminopeptidase 3 3.6703
EDN1 endothelin 1 3.63585
SQOR sulfide quinone oxidoreductase 3.6055
SPTAN1 spectrin, alpha, non-erythrocytic 1 3.5676
ITFG1 integrin alpha FG-GAP repeat containing 1 3.47805
ADAT1 adenosine deaminase, tRNA-specific 1 3.4116
RALB v-ral simian leukemia viral oncogene homolog B 3.3844
VAT1 vesicle amine transport 1 3.3404
MCOLN1 mucolipin 1 3.31035
TRIB1 tribbles pseudokinase 1 3.19095
FZD7 frizzled class receptor 7 3.12468
PRR15L proline rich 15-like 3.0861
BPHL biphenyl hydrolase-like (serine hydrolase) 2.9938
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.9683
TERF2IP telomeric repeat binding factor 2, interacting protein 2.9566
SLC38A2 solute carrier family 38, member 2 2.90125
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.89195
ASB8 ankyrin repeat and SOCS box containing 8 2.8917
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.88963
MACF1 microtubule-actin crosslinking factor 1 2.84314
GADD45A growth arrest and DNA-damage-inducible, alpha 2.8373
FAT1 FAT atypical cadherin 1 2.83165
ARHGAP9 Rho GTPase activating protein 9 2.79445
ATP9A ATPase, class II, type 9A 2.789
GADD45B growth arrest and DNA-damage-inducible, beta 2.74037
MBNL2 muscleblind-like splicing regulator 2 2.72933
ZNF589 zinc finger protein 589 2.7215
MOK MOK protein kinase 2.7104
MICALL1 MICAL-like 1 2.7098
TEAD3 TEA domain family member 3 2.67815
CLTB clathrin, light chain B 2.67314
TTLL7 tubulin tyrosine ligase-like family member 7 2.62775
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 2.58325
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 2.57365
CASC3 cancer susceptibility candidate 3 2.55515
IGF2R insulin-like growth factor 2 receptor 2.54868
ZMIZ1 zinc finger, MIZ-type containing 1 2.54285
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.5289
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.51353
CYCS cytochrome c, somatic 2.50185
TWF2 twinfilin actin binding protein 2 2.4913
AGTR1 angiotensin II receptor, type 1 2.47675
CEP57 centrosomal protein 57kDa 2.47158
PBLD phenazine biosynthesis-like protein domain containing 2.4558
SOX4 SRY (sex determining region Y)-box 4 2.45033
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 2.43412
C2CD2 C2 calcium-dependent domain containing 2 2.4319
PXDC1 PX domain containing 1 2.4157
MBNL1 muscleblind-like splicing regulator 1 2.41294
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 2.407
MAP7D1 MAP7 domain containing 1 2.40615
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 2.4008
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.3821
MCM3 minichromosome maintenance complex component 3 2.3656
KHDC4 KH domain containing 4, pre-mRNA splicing factor 2.3556
CYTH1 cytohesin 1 2.34685
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 2.33923
EMP1 epithelial membrane protein 1 2.33323
SUN2 Sad1 and UNC84 domain containing 2 2.32905
JADE1 jade family PHD finger 1 2.32455
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 2.32225
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 2.32215
KLHL21 kelch-like family member 21 2.30505
MGLL monoglyceride lipase 2.303
LPAR2 lysophosphatidic acid receptor 2 2.3004
AZIN2 antizyme inhibitor 2 2.29195
TASL TLR adaptor interacting with endolysosomal SLC15A4 2.2773
DGKD diacylglycerol kinase, delta 130kDa 2.27645
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 2.26815
MUC13 mucin 13, cell surface associated 2.2647
HOXC6 homeobox C6 2.25615
CD58 CD58 molecule 2.25377
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.2496
AMOTL2 angiomotin like 2 2.24825
GPATCH3 G patch domain containing 3 2.23935
CUL4B cullin 4B 2.22645
STIMATE STIM activating enhancer 2.22085
CYBRD1 cytochrome b reductase 1 2.20455
KEAP1 kelch-like ECH-associated protein 1 2.20085
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2.1889
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 2.18715
GOLT1B golgi transport 1B 2.1838
ANXA4 annexin A4 2.17725
PPARG peroxisome proliferator-activated receptor gamma 2.175
SLC35F5 solute carrier family 35, member F5 2.1709
ANO1 anoctamin 1, calcium activated chloride channel 2.1705
SRPX sushi-repeat containing protein, X-linked 2.1551
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 2.1545
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) 2.1418
SFXN3 sideroflexin 3 2.14125
MED15 mediator complex subunit 15 2.14
STOM stomatin 2.13818
BTNL8 butyrophilin-like 8 2.1372
HOOK2 hook microtubule-tethering protein 2 2.13477
AK5 adenylate kinase 5 2.1326
DSG2 desmoglein 2 2.1312
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 2.12955
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 2.12955
TLR4 toll-like receptor 4 2.1265
BAD BCL2-associated agonist of cell death 2.12
FLCN folliculin 2.1158
CCNDBP1 cyclin D-type binding-protein 1 2.1147
PRDX1 peroxiredoxin 1 2.11115
PFDN1 prefoldin subunit 1 2.10135
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 2.09915
ANXA11 annexin A11 2.09405
BECN1 beclin 1, autophagy related 2.0918
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.0875
PHACTR4 phosphatase and actin regulator 4 2.0872
SMG5 SMG5 nonsense mediated mRNA decay factor 2.08267
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.08065
EPS8 epidermal growth factor receptor pathway substrate 8 2.07525
EP300 E1A binding protein p300 2.06908
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 2.06817
ITGA9 integrin, alpha 9 2.067
JAM3 junctional adhesion molecule 3 2.06445
NIBAN1 niban apoptosis regulator 1 2.06435
DOHH deoxyhypusine hydroxylase/monooxygenase 2.0625
HMBOX1 homeobox containing 1 2.05405
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 2.05145
ABLIM3 actin binding LIM protein family, member 3 2.0494
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 2.04355
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.03675
ELL2 elongation factor, RNA polymerase II, 2 2.0357
DCK deoxycytidine kinase 2.0333
LSR lipolysis stimulated lipoprotein receptor 2.03145
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.02953
WDR47 WD repeat domain 47 2.02745
C15ORF38-AP3S2 C15orf38-AP3S2 readthrough 2.026
DCTN1 dynactin 1 2.0224
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 2.0148
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 2.01463
BLVRA biliverdin reductase A 2.01452
MTMR2 myotubularin related protein 2 2.01447
LAMP5 lysosomal-associated membrane protein family, member 5 2.01365
MYO9A myosin IXA 2.005
ZFHX3 zinc finger homeobox 3 2.00125
MAP3K3 mitogen-activated protein kinase kinase kinase 3 2.0009

decreased expression

Symbol Name Standardized Value
NT5DC2 5'-nucleotidase domain containing 2 -10.0
CDC20 cell division cycle 20 -10.0
PLK1 polo-like kinase 1 -8.9439
CASP7 caspase 7, apoptosis-related cysteine peptidase -8.05555
PSRC1 proline/serine-rich coiled-coil 1 -7.7736
ZW10 zw10 kinetochore protein -7.39605
TCTN1 tectonic family member 1 -7.07815
ANKRD10 ankyrin repeat domain 10 -6.9276
ISOC1 isochorismatase domain containing 1 -6.91285
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -6.36175
HAT1 histone acetyltransferase 1 -6.3189
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -6.1965
CCNB2 cyclin B2 -5.89575
ICAM3 intercellular adhesion molecule 3 -5.6731
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -5.5492
DDIT4 DNA-damage-inducible transcript 4 -5.4198
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -5.35285
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -5.24385
FASTKD5 FAST kinase domains 5 -5.0103
RXYLT1 ribitol xylosyltransferase 1 -4.88828
TOP2A topoisomerase (DNA) II alpha 170kDa -4.85275
BIRC5 baculoviral IAP repeat containing 5 -4.75158
RPIA ribose 5-phosphate isomerase A -4.66005
LDHD lactate dehydrogenase D -4.6269
CCNA2 cyclin A2 -4.6194
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -4.61037
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -4.586
AURKB aurora kinase B -4.3403
SPAG4 sperm associated antigen 4 -4.33875
MELK maternal embryonic leucine zipper kinase -4.25015
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -4.0762
LBR lamin B receptor -4.06745
B4GAT1 beta-1,4-glucuronyltransferase 1 -3.9183
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.88785
RBM15B RNA binding motif protein 15B -3.8387
CCNB1 cyclin B1 -3.82495
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -3.79585
NLRP2B NLR family pyrin domain containing 2B -3.73715
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -3.70848
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -3.69692
RUVBL1 RuvB-like AAA ATPase 1 -3.65285
LAGE3 L antigen family, member 3 -3.65
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.5013
UBE2C ubiquitin-conjugating enzyme E2C -3.48145
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.474
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -3.43263
RPP38 ribonuclease P/MRP 38kDa subunit -3.3828
NCAPD2 non-SMC condensin I complex, subunit D2 -3.3672
SDF2L1 stromal cell-derived factor 2-like 1 -3.324
C5 complement component 5 -3.21805
CBR1 carbonyl reductase 1 -3.21125
PECR peroxisomal trans-2-enoyl-CoA reductase -3.1385
NFIL3 nuclear factor, interleukin 3 regulated -3.1151
PGRMC1 progesterone receptor membrane component 1 -3.0746
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.0439
CDK4 cyclin-dependent kinase 4 -3.0424
THAP11 THAP domain containing 11 -3.0318
SOAT2 sterol O-acyltransferase 2 -3.0095
TCERG1 transcription elongation regulator 1 -2.97355
USP6NL USP6 N-terminal like -2.97345
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.97302
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.94998
KIF11 kinesin family member 11 -2.93075
ALDOC aldolase C, fructose-bisphosphate -2.9051
CHIC2 cysteine-rich hydrophobic domain 2 -2.8934
HSPA14 heat shock 70kDa protein 14 -2.84695
NIT1 nitrilase 1 -2.8144
FICD FIC domain containing -2.8119
HSPA8 heat shock 70kDa protein 8 -2.80385
CDKN3 cyclin-dependent kinase inhibitor 3 -2.80205
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.7924
ODF2 outer dense fiber of sperm tails 2 -2.78445
ECH1 enoyl CoA hydratase 1, peroxisomal -2.7765
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.7693
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -2.7616
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -2.7366
COPS7A COP9 signalosome subunit 7A -2.71885
BCL7C B-cell CLL/lymphoma 7C -2.71715
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -2.70895
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 -2.69335
MFF mitochondrial fission factor -2.65485
RIOX1 ribosomal oxygenase 1 -2.6153
NRIP1 nuclear receptor interacting protein 1 -2.61163
FGFR4 fibroblast growth factor receptor 4 -2.60403
SQLE squalene epoxidase -2.60098
TDP1 tyrosyl-DNA phosphodiesterase 1 -2.59995
FNDC11 fibronectin type III domain containing 11 -2.5999
CETN3 centrin, EF-hand protein, 3 -2.5968
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.59628
PRDX4 peroxiredoxin 4 -2.5949
TBC1D31 TBC1 domain family, member 31 -2.59275
NLRP4 NLR family, pyrin domain containing 4 -2.58935
NENF neudesin neurotrophic factor -2.58687
CRELD2 cysteine-rich with EGF-like domains 2 -2.56735
ZDHHC6 zinc finger, DHHC-type containing 6 -2.5648
TCEA2 transcription elongation factor A (SII), 2 -2.5576
TXNRD3 thioredoxin reductase 3 -2.5564
LYRM1 LYR motif containing 1 -2.55405
UPK1A uroplakin 1A -2.5524
UBE3C ubiquitin protein ligase E3C -2.5466
MRPS31 mitochondrial ribosomal protein S31 -2.54533
PDCD6 programmed cell death 6 -2.54265
PTCD1 pentatricopeptide repeat domain 1 -2.51275
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.50385
INTS3 integrator complex subunit 3 -2.4993
CDCA3 cell division cycle associated 3 -2.49365
MVK mevalonate kinase -2.47353
ANGPTL8 angiopoietin like 8 -2.4735
PARPBP PARP1 binding protein -2.46745
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.46245
SIRAL2 SIR2 antiphage like 2 -2.44715
COG4 component of oligomeric golgi complex 4 -2.42015
ENOPH1 enolase-phosphatase 1 -2.41905
PKP1 plakophilin 1 -2.41887
MSMO1 methylsterol monooxygenase 1 -2.4158
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.41355
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -2.4086
GTF2A2 general transcription factor IIA, 2, 12kDa -2.4023
TSEN34 TSEN34 tRNA splicing endonuclease subunit -2.4011
TRIP13 thyroid hormone receptor interactor 13 -2.39205
GOLPH3L golgi phosphoprotein 3-like -2.3856
DIO3 deiodinase, iodothyronine, type III -2.3856
PUS1 pseudouridylate synthase 1 -2.3824
TFDP1 transcription factor Dp-1 -2.3809
MCM9 minichromosome maintenance complex component 9 -2.3789
SPRR3 small proline-rich protein 3 -2.3736
HADH hydroxyacyl-CoA dehydrogenase -2.37123
LMBR1 limb development membrane protein 1 -2.36652
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.36105
ZNF835 zinc finger protein 835 -2.35875
KRCC1 lysine-rich coiled-coil 1 -2.35635
PRUNE1 prune exopolyphosphatase 1 -2.33847
HEBP1 heme binding protein 1 -2.33405
EXOSC8 exosome component 8 -2.33315
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -2.33235
PRMT3 protein arginine methyltransferase 3 -2.33055
EMC9 ER membrane protein complex subunit 9 -2.33005
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.3295
POLR1G RNA polymerase I subunit G -2.3276
HOXA11 homeobox A11 -2.3233
PYCR1 pyrroline-5-carboxylate reductase 1 -2.3203
RNF123 ring finger protein 123 -2.31655
EBAG9 estrogen receptor binding site associated, antigen, 9 -2.30778
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.30765
SPC25 SPC25, NDC80 kinetochore complex component -2.3066
PLD3 phospholipase D family, member 3 -2.3042
BLMH bleomycin hydrolase -2.2899
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -2.28755
CHEK2 checkpoint kinase 2 -2.28735
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.2869
EMC2 ER membrane protein complex subunit 2 -2.2799
MYCBP MYC binding protein -2.27525
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit -2.2671
GSTM2 glutathione S-transferase mu 2 (muscle) -2.25475
MLEC malectin -2.24555
CDK1 cyclin-dependent kinase 1 -2.24132
TMEM260 transmembrane protein 260 -2.2381
ELP4 elongator acetyltransferase complex subunit 4 -2.2345
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -2.23355
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.23045
EBNA1BP2 EBNA1 binding protein 2 -2.23025
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme -2.22895
C1R complement component 1, r subcomponent -2.2217
LOC128966622 putative protein N-methyltransferase FAM86B2 -2.22055
GPR50 G protein-coupled receptor 50 -2.21525
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.2151
HYOU1 hypoxia up-regulated 1 -2.20995
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.20875
CLCN2 chloride channel, voltage-sensitive 2 -2.20845
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.20375
SCD stearoyl-CoA desaturase (delta-9-desaturase) -2.1983
UBE3B ubiquitin protein ligase E3B -2.19727
HTD2 hydroxyacyl-thioester dehydratase type 2 -2.1921
SLC35B1 solute carrier family 35, member B1 -2.19175
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.19075
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -2.18995
CFAP20 cilia and flagella associated protein 20 -2.18675
TTYH1 tweety family member 1 -2.1846
TM7SF2 transmembrane 7 superfamily member 2 -2.18385
NUP93 nucleoporin 93kDa -2.1836
TPRA1 transmembrane protein, adipocyte asscociated 1 -2.1834
SPDL1 spindle apparatus coiled-coil protein 1 -2.18045
NDFIP1 Nedd4 family interacting protein 1 -2.17885
LOC102723996 ICOS ligand -2.1712
PEPD peptidase D -2.1618
SESN1 sestrin 1 -2.15445
MVD mevalonate (diphospho) decarboxylase -2.1539
TMEM267 transmembrane protein 267 -2.15205
TEX28 testis expressed 28 -2.1431
PIMREG PICALM interacting mitotic regulator -2.1375
RPRM reprimo, TP53 dependent G2 arrest mediator candidate -2.1373
HACL2 2-hydroxyacyl-CoA lyase 2 -2.135
MAP3K7 mitogen-activated protein kinase kinase kinase 7 -2.12423
CERS1 ceramide synthase 1 -2.12305
SPRR1A small proline-rich protein 1A -2.12157
GPD1L glycerol-3-phosphate dehydrogenase 1-like -2.12015
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 -2.1195
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.1043
BCCIP BRCA2 and CDKN1A interacting protein -2.10345
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase -2.10265
TMEM120B transmembrane protein 120B -2.0975
MAP3K12 mitogen-activated protein kinase kinase kinase 12 -2.08617
IFT27 intraflagellar transport 27 -2.08612
SPRR2B small proline-rich protein 2B -2.08455
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 -2.08215
TTC12 tetratricopeptide repeat domain 12 -2.0755
YBX2 Y box binding protein 2 -2.0752
RIDA reactive intermediate imine deaminase A homolog -2.07045
ELAVL1 ELAV like RNA binding protein 1 -2.06243
LIN7B lin-7 homolog B (C. elegans) -2.05875
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic -2.0581
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.0537
ZNRF4 zinc and ring finger 4 -2.05185
ADGRB2 adhesion G protein-coupled receptor B2 -2.04575
BCKDK branched chain ketoacid dehydrogenase kinase -2.03935
MMP11 matrix metallopeptidase 11 -2.03798
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.0377
GPR27 G protein-coupled receptor 27 -2.03395
CDC16 cell division cycle 16 -2.0332
FCHO1 FCH domain only 1 -2.0332
HDAC2 histone deacetylase 2 -2.0328
AMT aminomethyltransferase -2.02635
VWA5A von Willebrand factor A domain containing 5A -2.02025
GALR3 galanin receptor 3 -2.01505
MRPS16 mitochondrial ribosomal protein S16 -2.0099
CCNE1 cyclin E1 -2.00595
COQ3 coenzyme Q3 methyltransferase -2.00045
INTS8 integrator complex subunit 8 -2.00005