CRCGN008_HEPG2_24H:I05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methotrexate 1.29 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

431 genes differentially expressed following the CRCGN008_HEPG2_24H:I05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
CHMP6 charged multivesicular body protein 6 10.0
CNPY3 canopy FGF signaling regulator 3 7.72095
INPP1 inositol polyphosphate-1-phosphatase 6.9591
IER3 immediate early response 3 6.49615
TUBB6 tubulin, beta 6 class V 6.43125
NPDC1 neural proliferation, differentiation and control, 1 6.06445
TIMP2 TIMP metallopeptidase inhibitor 2 5.95355
NMU neuromedin U 5.7454
GLRX glutaredoxin (thioltransferase) 5.5239
UBQLN2 ubiquilin 2 5.5156
LCN2 lipocalin 2 5.51445
IGFBP3 insulin-like growth factor binding protein 3 5.45407
S100A4 S100 calcium binding protein A4 5.4494
KIFBP kinesin family binding protein 5.27725
ACOT9 acyl-CoA thioesterase 9 5.194
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 5.11805
MVP major vault protein 5.00765
BACE2 beta-site APP-cleaving enzyme 2 4.8692
LSR lipolysis stimulated lipoprotein receptor 4.6634
DUSP6 dual specificity phosphatase 6 4.51938
VGLL4 vestigial-like family member 4 4.51155
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 4.4978
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 4.4889
LGALS8 lectin, galactoside-binding, soluble, 8 4.36125
CCP110 centriolar coiled coil protein 110kDa 4.33055
ZFP36 ZFP36 ring finger protein 4.3189
INTS3 integrator complex subunit 3 4.12485
SQOR sulfide quinone oxidoreductase 4.0729
DDB2 damage-specific DNA binding protein 2, 48kDa 3.9265
CHN1 chimerin 1 3.8463
NPC1 Niemann-Pick disease, type C1 3.78842
VAT1 vesicle amine transport 1 3.7856
TRIB1 tribbles pseudokinase 1 3.66345
ITFG1 integrin alpha FG-GAP repeat containing 1 3.52455
EVL Enah/Vasp-like 3.3878
RALB v-ral simian leukemia viral oncogene homolog B 3.35083
SLC35F2 solute carrier family 35, member F2 3.34925
SPAG7 sperm associated antigen 7 3.3436
PRKCH protein kinase C, eta 3.30535
MICALL1 MICAL-like 1 3.29085
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 3.2511
MACF1 microtubule-actin crosslinking factor 1 3.18011
LAP3 leucine aminopeptidase 3 3.1783
MED15 mediator complex subunit 15 3.13475
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 3.0723
JOSD1 Josephin domain containing 1 3.0587
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 3.04905
CD2AP CD2-associated protein 3.03875
CDC45 cell division cycle 45 3.03625
MX1 MX dynamin-like GTPase 1 2.9965
NANOS3 nanos homolog 3 (Drosophila) 2.986
SOX4 SRY (sex determining region Y)-box 4 2.9849
TERF2IP telomeric repeat binding factor 2, interacting protein 2.9834
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.97205
LOC124907782 dual specificity protein phosphatase 22 2.95115
FBXO7 F-box protein 7 2.9506
FOS FBJ murine osteosarcoma viral oncogene homolog 2.9408
TWF2 twinfilin actin binding protein 2 2.85555
BRD9 bromodomain containing 9 2.8314
FAT1 FAT atypical cadherin 1 2.80045
JAM3 junctional adhesion molecule 3 2.77875
ATP11B ATPase, class VI, type 11B 2.76675
EGR1 early growth response 1 2.75925
IL4R interleukin 4 receptor 2.74815
STX18 syntaxin 18 2.71715
PTPN3 protein tyrosine phosphatase, non-receptor type 3 2.6881
LOC122526780 uncharacterized LOC122526780 2.66985
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.66003
BIRC2 baculoviral IAP repeat containing 2 2.6509
ANXA4 annexin A4 2.64118
IFI44 interferon-induced protein 44 2.6256
CASC3 cancer susceptibility candidate 3 2.62385
NNT nicotinamide nucleotide transhydrogenase 2.61985
GOLT1B golgi transport 1B 2.6098
SQSTM1 sequestosome 1 2.57005
ERCC5 excision repair cross-complementation group 5 2.5627
KHDC4 KH domain containing 4, pre-mRNA splicing factor 2.5447
EDN1 endothelin 1 2.5355
UBR2 ubiquitin protein ligase E3 component n-recognin 2 2.52962
TMEM140 transmembrane protein 140 2.51445
ZDHHC7 zinc finger, DHHC-type containing 7 2.51245
IFI6 interferon, alpha-inducible protein 6 2.49995
GTPBP2 GTP binding protein 2 2.4929
LGALS9C lectin, galactoside-binding, soluble, 9C 2.4918
SFXN3 sideroflexin 3 2.48935
CD58 CD58 molecule 2.4851
DCK deoxycytidine kinase 2.45595
RSAD2 radical S-adenosyl methionine domain containing 2 2.44155
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.43452
SLC75A1 solute carrier family 75 member 1 2.4273
ZNF589 zinc finger protein 589 2.4171
JADE2 jade family PHD finger 2 2.4142
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.4008
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 2.3954
DSG2 desmoglein 2 2.39445
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.3732
KIF2A kinesin heavy chain member 2A 2.35992
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 2.35227
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.3507
MTCH1 mitochondrial carrier 1 2.34995
TJP2 tight junction protein 2 2.34475
KRABD4 KRAB domain containing 4 2.34155
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.3369
PXDC1 PX domain containing 1 2.3264
SAMD9 sterile alpha motif domain containing 9 2.3253
MBNL1 muscleblind-like splicing regulator 1 2.31592
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.30845
S100A13 S100 calcium binding protein A13 2.30253
FXYD2 FXYD domain containing ion transport regulator 2 2.29525
OFD1 oral-facial-digital syndrome 1 2.29205
PRPF38B pre-mRNA processing factor 38B 2.29075
ELP3 elongator acetyltransferase complex subunit 3 2.2893
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 2.2845
LARS1 leucyl-tRNA synthetase 1 2.2644
YIPF3 Yip1 domain family, member 3 2.24335
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 2.24095
MBNL2 muscleblind-like splicing regulator 2 2.228
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.22725
CDC25B cell division cycle 25B 2.2192
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.21385
RIOK3 RIO kinase 3 2.20963
ZNF195 zinc finger protein 195 2.2025
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.20225
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.1916
BLVRA biliverdin reductase A 2.18318
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.18135
SPATA20 spermatogenesis associated 20 2.177
ATF3 activating transcription factor 3 2.16915
CYTH1 cytohesin 1 2.16007
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 2.14832
C2CD2 C2 calcium-dependent domain containing 2 2.14335
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 2.13915
TASL TLR adaptor interacting with endolysosomal SLC15A4 2.12125
CMTR1 cap methyltransferase 1 2.11385
PPA1 pyrophosphatase (inorganic) 1 2.11225
GOLGA3 golgin A3 2.10805
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.10145
PARP8 poly (ADP-ribose) polymerase family, member 8 2.0962
GTPBP8 GTP-binding protein 8 (putative) 2.09445
CDK7 cyclin-dependent kinase 7 2.0903
SYNGR3 synaptogyrin 3 2.0864
IFI44L interferon-induced protein 44-like 2.08345
GHITM growth hormone inducible transmembrane protein 2.07963
CHMP5 charged multivesicular body protein 5 2.0792
DKK1 dickkopf WNT signaling pathway inhibitor 1 2.0758
ATP9A ATPase, class II, type 9A 2.06395
LIMA1 LIM domain and actin binding 1 2.0628
VNN1 vanin 1 2.06025
ISG15 ISG15 ubiquitin-like modifier 2.04435
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.04225
BYSL bystin-like 2.04115
KLF3 Kruppel-like factor 3 (basic) 2.03655
FAAP100 FA core complex associated protein 100 2.01765
ITGB5 integrin, beta 5 2.0158
SLC38A2 solute carrier family 38, member 2 2.01565
RGPD2 RANBP2-like and GRIP domain containing 2 2.01285
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 2.01035
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 2.01025
ZFAND5 zinc finger, AN1-type domain 5 2.00828
TOPBP1 topoisomerase (DNA) II binding protein 1 2.00755
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 2.0045
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 2.0003

decreased expression

Symbol Name Standardized Value
CDC20 cell division cycle 20 -10.0
NT5DC2 5'-nucleotidase domain containing 2 -8.40885
PLK1 polo-like kinase 1 -7.4818
PSRC1 proline/serine-rich coiled-coil 1 -7.05475
TCTN1 tectonic family member 1 -6.9473
ISOC1 isochorismatase domain containing 1 -6.82745
ANKRD10 ankyrin repeat domain 10 -6.6339
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -6.58565
ZW10 zw10 kinetochore protein -6.5684
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -6.4185
ICAM3 intercellular adhesion molecule 3 -6.3519
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -6.25795
CCNB2 cyclin B2 -5.7005
CCNA2 cyclin A2 -5.50765
CD320 CD320 molecule -5.41785
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -5.08245
HLA-DMA major histocompatibility complex, class II, DM alpha -5.0709
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -5.0613
FABP5 fatty acid binding protein 5 (psoriasis-associated) -5.0
RPS4Y1 ribosomal protein S4, Y-linked 1 -5.0
CASP7 caspase 7, apoptosis-related cysteine peptidase -4.99855
RXYLT1 ribitol xylosyltransferase 1 -4.95915
PCNA proliferating cell nuclear antigen -4.77245
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.70845
DDIT4 DNA-damage-inducible transcript 4 -4.6021
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -4.5945
NIT1 nitrilase 1 -4.5362
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.44347
RUVBL1 RuvB-like AAA ATPase 1 -4.32465
PCCB propionyl CoA carboxylase, beta polypeptide -4.31065
MRPS2 mitochondrial ribosomal protein S2 -4.30005
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -4.21615
B4GAT1 beta-1,4-glucuronyltransferase 1 -4.1283
FASTKD5 FAST kinase domains 5 -4.09105
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -4.0618
RBM15B RNA binding motif protein 15B -4.0529
CASP3 caspase 3, apoptosis-related cysteine peptidase -4.05155
RPIA ribose 5-phosphate isomerase A -3.9893
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -3.9479
AURKB aurora kinase B -3.86125
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -3.8406
NR2F6 nuclear receptor subfamily 2, group F, member 6 -3.83293
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -3.8259
NCAPD2 non-SMC condensin I complex, subunit D2 -3.8091
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.80815
TOP2A topoisomerase (DNA) II alpha 170kDa -3.76815
LBR lamin B receptor -3.75945
CDK1 cyclin-dependent kinase 1 -3.7004
BIRC5 baculoviral IAP repeat containing 5 -3.60622
LAGE3 L antigen family, member 3 -3.53
TSPAN4 tetraspanin 4 -3.52927
CDCA3 cell division cycle associated 3 -3.49615
SCAND1 SCAN domain containing 1 -3.47035
NENF neudesin neurotrophic factor -3.40235
GTF2A2 general transcription factor IIA, 2, 12kDa -3.3255
KDM3A lysine (K)-specific demethylase 3A -3.3188
RPP38 ribonuclease P/MRP 38kDa subunit -3.27775
MYC v-myc avian myelocytomatosis viral oncogene homolog -3.2618
NLRP2B NLR family pyrin domain containing 2B -3.2106
MRPL12 mitochondrial ribosomal protein L12 -3.2058
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.1984
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -3.1572
CCNB1 cyclin B1 -3.1115
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 -3.08205
MAPK9 mitogen-activated protein kinase 9 -3.07975
PECR peroxisomal trans-2-enoyl-CoA reductase -3.0781
UBE3C ubiquitin protein ligase E3C -3.06135
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -3.0423
SDF2L1 stromal cell-derived factor 2-like 1 -3.0012
TEDC2 tubulin epsilon and delta complex 2 -2.98455
CDKN3 cyclin-dependent kinase inhibitor 3 -2.9835
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.98125
UBE2C ubiquitin-conjugating enzyme E2C -2.9566
ERCC6L excision repair cross-complementation group 6-like -2.92835
CCDC86 coiled-coil domain containing 86 -2.86305
ZFY zinc finger protein, Y-linked -2.8622
POU4F2 POU class 4 homeobox 2 -2.859
DIO3 deiodinase, iodothyronine, type III -2.8377
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.81095
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme -2.80895
PRUNE1 prune exopolyphosphatase 1 -2.80623
SOAT2 sterol O-acyltransferase 2 -2.79645
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -2.7773
PYCR1 pyrroline-5-carboxylate reductase 1 -2.7603
PEX11A peroxisomal biogenesis factor 11 alpha -2.7299
HEBP1 heme binding protein 1 -2.72855
MRPL17 mitochondrial ribosomal protein L17 -2.70135
HADH hydroxyacyl-CoA dehydrogenase -2.69678
SYCP1 synaptonemal complex protein 1 -2.68928
CENPA centromere protein A -2.67403
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -2.65295
ELAVL1 ELAV like RNA binding protein 1 -2.64175
ALG8 ALG8, alpha-1,3-glucosyltransferase -2.6325
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -2.6321
SCARB1 scavenger receptor class B, member 1 -2.6312
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.62775
KDM5D lysine (K)-specific demethylase 5D -2.6276
OXA1L oxidase (cytochrome c) assembly 1-like -2.62335
THAP11 THAP domain containing 11 -2.61005
DHCR7 7-dehydrocholesterol reductase -2.60932
TMEM161A transmembrane protein 161A -2.59757
PDIA6 protein disulfide isomerase family A, member 6 -2.59066
MLEC malectin -2.58127
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.57932
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -2.57505
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.57327
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 -2.56995
COQ3 coenzyme Q3 methyltransferase -2.5649
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -2.56295
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -2.55705
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.55565
COPS7A COP9 signalosome subunit 7A -2.5551
PYCR3 pyrroline-5-carboxylate reductase 3 -2.554
GYG2 glycogenin 2 -2.5442
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -2.5151
MELK maternal embryonic leucine zipper kinase -2.50985
TBC1D31 TBC1 domain family, member 31 -2.50575
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -2.4918
MTARC1 mitochondrial amidoxime reducing component 1 -2.48065
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.47855
MRPL3 mitochondrial ribosomal protein L3 -2.47695
NEK2 NIMA-related kinase 2 -2.47333
LIN7B lin-7 homolog B (C. elegans) -2.4664
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.46365
HMGB2 high mobility group box 2 -2.46175
KDM4D lysine (K)-specific demethylase 4D -2.46055
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -2.4595
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -2.4536
AAMP angio-associated, migratory cell protein -2.4441
REEP5 receptor accessory protein 5 -2.44327
PDZD2 PDZ domain containing 2 -2.4324
ACO1 aconitase 1, soluble -2.4285
RLF rearranged L-myc fusion -2.42705
STK16 serine/threonine kinase 16 -2.42135
SMCO4 single-pass membrane protein with coiled-coil domains 4 -2.41935
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -2.39265
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -2.3792
GAN gigaxonin -2.3783
IP6K1 inositol hexakisphosphate kinase 1 -2.37575
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.3746
FAM184A family with sequence similarity 184, member A -2.37
LYRM1 LYR motif containing 1 -2.3689
RITA1 RBPJ interacting and tubulin associated 1 -2.36342
USP9Y ubiquitin specific peptidase 9, Y-linked -2.35558
NR1H3 nuclear receptor subfamily 1, group H, member 3 -2.34955
PKDREJ polycystin (PKD) family receptor for egg jelly -2.34195
GPT glutamic-pyruvate transaminase (alanine aminotransferase) -2.34055
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.33885
LOC102724594 splicing factor U2AF 35 kDa subunit -2.3311
OR7E24 olfactory receptor, family 7, subfamily E, member 24 -2.331
DHCR24 24-dehydrocholesterol reductase -2.3198
LDHAL6B lactate dehydrogenase A-like 6B -2.31715
PDCD5 programmed cell death 5 -2.31165
EMC9 ER membrane protein complex subunit 9 -2.3099
ENOPH1 enolase-phosphatase 1 -2.30675
TCERG1 transcription elongation regulator 1 -2.3064
STON1-GTF2A1L STON1-GTF2A1L readthrough -2.29865
FGFR4 fibroblast growth factor receptor 4 -2.2985
MSH6 mutS homolog 6 -2.29052
GAMT guanidinoacetate N-methyltransferase -2.2829
SPATA6 spermatogenesis associated 6 -2.27607
KCNK7 potassium channel, two pore domain subfamily K, member 7 -2.27105
NCKIPSD NCK interacting protein with SH3 domain -2.2694
MANF mesencephalic astrocyte-derived neurotrophic factor -2.26935
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic -2.26605
CALB2 calbindin 2 -2.26585
SCGB2A2 secretoglobin, family 2A, member 2 -2.26285
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.26055
PARPBP PARP1 binding protein -2.2514
INCENP inner centromere protein antigens 135/155kDa -2.25135
BLMH bleomycin hydrolase -2.2511
NRIP1 nuclear receptor interacting protein 1 -2.24855
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.2451
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -2.24265
RNASE4 ribonuclease, RNase A family, 4 -2.23915
BTG4 B-cell translocation gene 4 -2.2381
PNPLA3 patatin-like phospholipase domain containing 3 -2.23585
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -2.2315
SAP130 Sin3A-associated protein, 130kDa -2.23125
RNF139 ring finger protein 139 -2.22995
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.2236
POLD2 polymerase (DNA directed), delta 2, accessory subunit -2.2172
ATG3 autophagy related 3 -2.2136
ACAA1 acetyl-CoA acyltransferase 1 -2.21158
GHRH growth hormone releasing hormone -2.21095
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -2.2097
MLANA melan-A -2.20843
MYCBP MYC binding protein -2.20757
AQP4 aquaporin 4 -2.20636
CNOT7 CCR4-NOT transcription complex, subunit 7 -2.19925
CCNF cyclin F -2.19922
HSPA14 heat shock 70kDa protein 14 -2.197
SOX30 SRY (sex determining region Y)-box 30 -2.1955
PRR7 proline rich 7 (synaptic) -2.1944
TPI1 triosephosphate isomerase 1 -2.19313
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -2.18855
USP39 ubiquitin specific peptidase 39 -2.17925
CDCA8 cell division cycle associated 8 -2.17415
ELOVL2 ELOVL fatty acid elongase 2 -2.16625
NLGN4Y neuroligin 4, Y-linked -2.16585
DBF4 DBF4 zinc finger -2.16385
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -2.16375
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.16365
TYR tyrosinase -2.1631
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 -2.163
ANKRD7 ankyrin repeat domain 7 -2.1615
PEX5 peroxisomal biogenesis factor 5 -2.15523
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.15185
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 -2.1476
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -2.1364
SNIP1 Smad nuclear interacting protein 1 -2.12975
HYOU1 hypoxia up-regulated 1 -2.1286
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.12825
SCAP SREBF chaperone -2.12705
EYA3 EYA transcriptional coactivator and phosphatase 3 -2.12605
AKAP3 A kinase (PRKA) anchor protein 3 -2.12605
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) -2.12485
PTTG1 pituitary tumor-transforming 1 -2.12155
SDC3 syndecan 3 -2.11755
NEU2 sialidase 2 (cytosolic sialidase) -2.1142
AMELX amelogenin, X-linked -2.1109
PIMREG PICALM interacting mitotic regulator -2.11075
ECH1 enoyl CoA hydratase 1, peroxisomal -2.0986
BRD2 bromodomain containing 2 -2.09822
KIFC1 kinesin family member C1 -2.0976
ABHD14A abhydrolase domain containing 14A -2.0913
CBR1 carbonyl reductase 1 -2.09075
KIF15 kinesin family member 15 -2.09015
TUBAL3 tubulin, alpha-like 3 -2.0867
GPC5 glypican 5 -2.08285
SCD stearoyl-CoA desaturase (delta-9-desaturase) -2.08069
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -2.07885
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked -2.07793
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B -2.076
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 -2.0715
WDR62 WD repeat domain 62 -2.07075
PREB prolactin regulatory element binding -2.0707
BAX BCL2-associated X protein -2.06845
CDH20 cadherin 20, type 2 -2.0677
INTS8 integrator complex subunit 8 -2.0659
CXCL9 chemokine (C-X-C motif) ligand 9 -2.06565
PGK2 phosphoglycerate kinase 2 -2.05885
FBXO5 F-box protein 5 -2.05625
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -2.0541
PDIA3 protein disulfide isomerase family A, member 3 -2.05235
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 -2.0472
TMED9 transmembrane emp24 protein transport domain containing 9 -2.04303
ZPBP zona pellucida binding protein -2.04155
REEP4 receptor accessory protein 4 -2.039
PAX3 paired box 3 -2.03348
UBE2S ubiquitin-conjugating enzyme E2S -2.0314
ADCY10 adenylate cyclase 10 (soluble) -2.03025
DIAPH3 diaphanous-related formin 3 -2.02825
GUCA1B guanylate cyclase activator 1B (retina) -2.02495
EBAG9 estrogen receptor binding site associated, antigen, 9 -2.0242
JAKMIP2 janus kinase and microtubule interacting protein 2 -2.02355
ATRAID all-trans retinoic acid-induced differentiation factor -2.0211
TMEM109 transmembrane protein 109 -2.01935
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria -2.01865
LHX1 LIM homeobox 1 -2.0147
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -2.0143
RNF32 ring finger protein 32 -2.0128
PRCP prolylcarboxypeptidase (angiotensinase C) -2.00915
PAX7 paired box 7 -2.0082
DUS2 dihydrouridine synthase 2 -2.00418
TLL1 tolloid-like 1 -2.004
SPAG6 sperm associated antigen 6 -2.00332
KCTD11 potassium channel tetramerization domain containing 11 -2.00205