CRCGN008_HEPG2_24H:I06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methotrexate 0.65 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

420 genes differentially expressed following the CRCGN008_HEPG2_24H:I06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
CNPY3 canopy FGF signaling regulator 3 8.28175
INPP1 inositol polyphosphate-1-phosphatase 7.7927
KIFBP kinesin family binding protein 7.2075
TUBB6 tubulin, beta 6 class V 6.8557
NPDC1 neural proliferation, differentiation and control, 1 6.589
TIMP2 TIMP metallopeptidase inhibitor 2 6.52315
IGFBP3 insulin-like growth factor binding protein 3 6.48298
PPARG peroxisome proliferator-activated receptor gamma 5.77255
ZFP36 ZFP36 ring finger protein 5.6988
C2CD2 C2 calcium-dependent domain containing 2 5.4424
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 5.42575
CDC45 cell division cycle 45 5.32045
IER3 immediate early response 3 5.2356
GLRX glutaredoxin (thioltransferase) 4.96548
ACOT9 acyl-CoA thioesterase 9 4.94215
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.91055
MVP major vault protein 4.778
S100A4 S100 calcium binding protein A4 4.73865
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.7127
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 4.6539
SQOR sulfide quinone oxidoreductase 4.61155
LGALS8 lectin, galactoside-binding, soluble, 8 4.54649
DUSP6 dual specificity phosphatase 6 4.44803
CCP110 centriolar coiled coil protein 110kDa 4.18475
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 4.0543
RALB v-ral simian leukemia viral oncogene homolog B 3.9111
BAD BCL2-associated agonist of cell death 3.89787
EDN1 endothelin 1 3.8884
DDB2 damage-specific DNA binding protein 2, 48kDa 3.8568
BPHL biphenyl hydrolase-like (serine hydrolase) 3.7877
TRIB1 tribbles pseudokinase 1 3.75085
SLC35F2 solute carrier family 35, member F2 3.71055
AUP1 ancient ubiquitous protein 1 3.64275
SPAG7 sperm associated antigen 7 3.53085
CHN1 chimerin 1 3.4819
H2BC12 H2B clustered histone 12 3.405
GSTZ1 glutathione S-transferase zeta 1 3.37145
RBPJ recombination signal binding protein for immunoglobulin kappa J region 3.32897
GPER1 G protein-coupled estrogen receptor 1 3.32255
VAT1 vesicle amine transport 1 3.295
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 3.22145
SLC75A1 solute carrier family 75 member 1 3.21485
KHDC4 KH domain containing 4, pre-mRNA splicing factor 3.18615
JADE2 jade family PHD finger 2 3.14967
TWF2 twinfilin actin binding protein 2 3.0851
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 3.0535
TERF2IP telomeric repeat binding factor 2, interacting protein 3.02295
AMOTL2 angiomotin like 2 3.0205
SQSTM1 sequestosome 1 2.98945
EPHA2 EPH receptor A2 2.98355
FBXO7 F-box protein 7 2.96065
BLVRA biliverdin reductase A 2.92613
SKIC2 SKI2 subunit of superkiller complex 2.8855
ERCC5 excision repair cross-complementation group 5 2.8826
MICALL1 MICAL-like 1 2.88087
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 2.8773
ARL4C ADP-ribosylation factor-like 4C 2.87365
CLTB clathrin, light chain B 2.86889
GNL1 guanine nucleotide binding protein-like 1 2.8501
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.8471
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 2.79848
RAI14 retinoic acid induced 14 2.77985
CRTAP cartilage associated protein 2.76105
RB1CC1 RB1-inducible coiled-coil 1 2.73273
TNIP1 TNFAIP3 interacting protein 1 2.7302
MACF1 microtubule-actin crosslinking factor 1 2.72528
PXDC1 PX domain containing 1 2.7161
BAG3 BCL2-associated athanogene 3 2.69215
JOSD1 Josephin domain containing 1 2.67165
PROCR protein C receptor, endothelial 2.66895
SF3B2 splicing factor 3b, subunit 2, 145kDa 2.66485
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 2.6602
CD58 CD58 molecule 2.64917
CEP57 centrosomal protein 57kDa 2.62734
DOHH deoxyhypusine hydroxylase/monooxygenase 2.6139
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 2.6131
CAMLG calcium modulating ligand 2.57265
CDK7 cyclin-dependent kinase 7 2.57035
TIMP1 TIMP metallopeptidase inhibitor 1 2.5538
GOLT1B golgi transport 1B 2.5495
PNKP polynucleotide kinase 3'-phosphatase 2.5423
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.5322
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 2.52542
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 2.5212
PLK3 polo-like kinase 3 2.48725
WDR13 WD repeat domain 13 2.48075
FAT1 FAT atypical cadherin 1 2.4786
TOMM34 translocase of outer mitochondrial membrane 34 2.47845
LAP3 leucine aminopeptidase 3 2.4565
DNM3 dynamin 3 2.44935
LOC124907782 dual specificity protein phosphatase 22 2.4407
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.43295
RBMS2 RNA binding motif, single stranded interacting protein 2 2.4254
MON1B MON1 secretory trafficking family member B 2.42465
NMU neuromedin U 2.4243
MBNL1 muscleblind-like splicing regulator 1 2.40838
CD63 CD63 molecule 2.40665
VGLL4 vestigial-like family member 4 2.40352
ZMIZ1 zinc finger, MIZ-type containing 1 2.3998
PTTG1IP pituitary tumor-transforming 1 interacting protein 2.3991
ATP9A ATPase, class II, type 9A 2.39855
IL3RA interleukin 3 receptor, alpha (low affinity) 2.39515
SFXN3 sideroflexin 3 2.37107
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.368
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.3596
STN1 STN1 subunit of CST complex 2.3574
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12) 2.354
ZNF205 zinc finger protein 205 2.3539
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific 2.35
DKK1 dickkopf WNT signaling pathway inhibitor 1 2.34855
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 2.34745
KCTD17 potassium channel tetramerization domain containing 17 2.3417
MGLL monoglyceride lipase 2.33845
SMAD3 SMAD family member 3 2.33214
GABARAPL1 GABA(A) receptor-associated protein like 1 2.32512
TNIP2 TNFAIP3 interacting protein 2 2.31765
TRIM8 tripartite motif containing 8 2.31675
EIF4A2 eukaryotic translation initiation factor 4A2 2.31545
WASF3 WAS protein family, member 3 2.31105
SART1 squamous cell carcinoma antigen recognized by T cells 2.30325
TMEM50A transmembrane protein 50A 2.2903
SERINC1 serine incorporator 1 2.28055
ATF3 activating transcription factor 3 2.27575
AGTR1 angiotensin II receptor, type 1 2.2667
EGR1 early growth response 1 2.26588
CASC3 cancer susceptibility candidate 3 2.2654
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.26327
APP amyloid beta (A4) precursor protein 2.26067
ANXA11 annexin A11 2.2557
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 2.25505
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.2512
EMP1 epithelial membrane protein 1 2.24463
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 2.24335
DDR1 discoidin domain receptor tyrosine kinase 1 2.24235
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.23655
DSG2 desmoglein 2 2.2208
UBR2 ubiquitin protein ligase E3 component n-recognin 2 2.21843
RASAL2 RAS protein activator like 2 2.2177
SOX4 SRY (sex determining region Y)-box 4 2.21675
SUN2 Sad1 and UNC84 domain containing 2 2.2157
MTCH1 mitochondrial carrier 1 2.21445
TM9SF2 transmembrane 9 superfamily member 2 2.2134
TESK1 testis-specific kinase 1 2.2129
IL4R interleukin 4 receptor 2.21025
GPRC5A G protein-coupled receptor, class C, group 5, member A 2.1964
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 2.1936
GDI1 GDP dissociation inhibitor 1 2.17945
POLH polymerase (DNA directed), eta 2.16925
RAB4A RAB4A, member RAS oncogene family 2.16372
ADGRG6 adhesion G protein-coupled receptor G6 2.1634
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 2.1627
FXYD5 FXYD domain containing ion transport regulator 5 2.15385
CTTN cortactin 2.14422
MED15 mediator complex subunit 15 2.1441
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.13618
NR2F2 nuclear receptor subfamily 2, group F, member 2 2.13211
PICK1 protein interacting with PRKCA 1 2.1302
RAB13 RAB13, member RAS oncogene family 2.1266
DYNLT3 dynein, light chain, Tctex-type 3 2.12555
TBC1D15 TBC1 domain family, member 15 2.11425
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 2.11245
SRP54 signal recognition particle 54kDa 2.11205
SYF2 SYF2 pre-mRNA-splicing factor 2.1035
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 2.10302
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) 2.1025
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 2.1022
ABLIM3 actin binding LIM protein family, member 3 2.09835
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 2.09215
SAA2 serum amyloid A2 2.08973
METTL25B methyltransferase like 25B 2.08135
TSPAN6 tetraspanin 6 2.07925
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.07515
MYO9A myosin IXA 2.07515
ZC3H7A zinc finger CCCH-type containing 7A 2.07485
TXNL4B thioredoxin-like 4B 2.07415
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.0709
ECD ecdysoneless homolog (Drosophila) 2.0658
STX12 syntaxin 12 2.06518
POLL polymerase (DNA directed), lambda 2.0627
DDAH1 dimethylarginine dimethylaminohydrolase 1 2.0607
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 2.05657
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 2.04395
CEP170 centrosomal protein 170kDa 2.04058
MAP1S microtubule-associated protein 1S 2.03995
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 2.0316
ADGRF1 adhesion G protein-coupled receptor F1 2.02785
CYFIP1 cytoplasmic FMR1 interacting protein 1 2.02525
OR10H1 olfactory receptor, family 10, subfamily H, member 1 2.0227
IGF2R insulin-like growth factor 2 receptor 2.022
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2.01765
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 2.01667
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 2.01533
CUEDC2 CUE domain containing 2 2.0141
EHD4 EH-domain containing 4 2.01285
AXIN1 axin 1 2.00925
ITGB5 integrin, beta 5 2.008
NGFR nerve growth factor receptor 2.00265

decreased expression

Symbol Name Standardized Value
CDC20 cell division cycle 20 -10.0
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -10.0
NT5DC2 5'-nucleotidase domain containing 2 -9.91875
CCNB2 cyclin B2 -8.53215
PLK1 polo-like kinase 1 -8.32805
ISOC1 isochorismatase domain containing 1 -7.16885
TCTN1 tectonic family member 1 -7.03535
ZW10 zw10 kinetochore protein -6.5233
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -6.2702
MAPK13 mitogen-activated protein kinase 13 -6.2211
TLCD3A TLC domain containing 3A -6.04935
PSRC1 proline/serine-rich coiled-coil 1 -6.01105
CCNA2 cyclin A2 -5.76222
ICAM3 intercellular adhesion molecule 3 -5.7488
CCNB1 cyclin B1 -5.73285
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -5.33725
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -5.3371
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -5.08918
CDK1 cyclin-dependent kinase 1 -4.99953
TOP2A topoisomerase (DNA) II alpha 170kDa -4.8708
ADI1 acireductone dioxygenase 1 -4.64075
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.63648
ANKRD10 ankyrin repeat domain 10 -4.62615
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -4.6129
RXYLT1 ribitol xylosyltransferase 1 -4.60103
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -4.55373
DDIT4 DNA-damage-inducible transcript 4 -4.54955
RUVBL1 RuvB-like AAA ATPase 1 -4.47995
ZNF586 zinc finger protein 586 -4.312
AURKB aurora kinase B -4.27185
FASTKD5 FAST kinase domains 5 -4.24815
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -4.2453
MRPS2 mitochondrial ribosomal protein S2 -4.2356
LDHD lactate dehydrogenase D -4.2012
CDKN3 cyclin-dependent kinase inhibitor 3 -4.1939
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -4.17005
UBE2C ubiquitin-conjugating enzyme E2C -4.13075
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -4.0684
KDM3A lysine (K)-specific demethylase 3A -3.93255
PDZD2 PDZ domain containing 2 -3.88168
ALG6 ALG6, alpha-1,3-glucosyltransferase -3.85995
RPIA ribose 5-phosphate isomerase A -3.84325
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -3.80175
PECR peroxisomal trans-2-enoyl-CoA reductase -3.74125
NLRP2B NLR family pyrin domain containing 2B -3.6754
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -3.65345
LBR lamin B receptor -3.6532
RFC2 replication factor C (activator 1) 2, 40kDa -3.62875
LAGE3 L antigen family, member 3 -3.61365
UBE2S ubiquitin-conjugating enzyme E2S -3.6002
ARID5B AT rich interactive domain 5B (MRF1-like) -3.58515
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -3.5371
ITFG1 integrin alpha FG-GAP repeat containing 1 -3.4447
MELK maternal embryonic leucine zipper kinase -3.36855
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -3.3607
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -3.3319
BIRC5 baculoviral IAP repeat containing 5 -3.32818
MRPL12 mitochondrial ribosomal protein L12 -3.3061
SCAND1 SCAN domain containing 1 -3.2855
HSPA8 heat shock 70kDa protein 8 -3.28523
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -3.2769
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -3.2736
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -3.24795
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.21263
LYSET lysosomal enzyme trafficking factor -3.17185
B4GAT1 beta-1,4-glucuronyltransferase 1 -3.1327
NCAPD2 non-SMC condensin I complex, subunit D2 -3.10035
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -3.01645
NUP37 nucleoporin 37kDa -3.0059
KIF4A kinesin family member 4A -2.9895
TRMT5 tRNA methyltransferase 5 -2.97065
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.95135
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.94707
NENF neudesin neurotrophic factor -2.93833
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.93495
C5 complement component 5 -2.92825
NFIL3 nuclear factor, interleukin 3 regulated -2.917
UBE3C ubiquitin protein ligase E3C -2.87015
GPATCH2 G patch domain containing 2 -2.8632
NIT1 nitrilase 1 -2.80355
UBE2M ubiquitin-conjugating enzyme E2M -2.8031
HMGN2 high mobility group nucleosomal binding domain 2 -2.7834
TMEM109 transmembrane protein 109 -2.7691
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.75645
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.7542
RFPL2 ret finger protein-like 2 -2.7538
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 -2.73405
RIOX1 ribosomal oxygenase 1 -2.70625
CLDN15 claudin 15 -2.67465
MRPL4 mitochondrial ribosomal protein L4 -2.6672
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.66025
PROS1 protein S (alpha) -2.65405
AGMAT agmatine ureohydrolase (agmatinase) -2.6435
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.63625
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -2.63448
CHL1 cell adhesion molecule L1-like -2.6328
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.63085
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -2.6155
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -2.60445
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) -2.5992
FGFR4 fibroblast growth factor receptor 4 -2.58595
RNF123 ring finger protein 123 -2.58395
CA14 carbonic anhydrase XIV -2.5837
NLRX1 NLR family member X1 -2.58345
MYC v-myc avian myelocytomatosis viral oncogene homolog -2.5573
GRPR gastrin-releasing peptide receptor -2.5521
VAV3 vav 3 guanine nucleotide exchange factor -2.548
MRPS7 mitochondrial ribosomal protein S7 -2.54735
CENPA centromere protein A -2.53547
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -2.53355
BCL7C B-cell CLL/lymphoma 7C -2.5254
LYRM1 LYR motif containing 1 -2.52435
MYCBP MYC binding protein -2.5209
LIN7B lin-7 homolog B (C. elegans) -2.4985
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -2.4949
PRMT1 protein arginine methyltransferase 1 -2.4938
CXCL2 chemokine (C-X-C motif) ligand 2 -2.47725
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -2.47615
CCDC92 coiled-coil domain containing 92 -2.47265
NEK2 NIMA-related kinase 2 -2.4516
FBXL4 F-box and leucine-rich repeat protein 4 -2.4487
ZNF559-ZNF177 ZNF559-ZNF177 readthrough -2.44775
ELAVL1 ELAV like RNA binding protein 1 -2.41598
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -2.41345
TESK2 testis-specific kinase 2 -2.39605
HBQ1 hemoglobin, theta 1 -2.3908
PEPD peptidase D -2.38005
GATA4 GATA binding protein 4 -2.3784
CER1 cerberus 1, DAN family BMP antagonist -2.37295
ZNF154 zinc finger protein 154 -2.3729
PRR7 proline rich 7 (synaptic) -2.3711
EPHA1 EPH receptor A1 -2.36735
MDH2 malate dehydrogenase 2, NAD (mitochondrial) -2.36727
MSH6 mutS homolog 6 -2.36285
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.3609
PRDX4 peroxiredoxin 4 -2.3571
LY86 lymphocyte antigen 86 -2.3531
INTS3 integrator complex subunit 3 -2.34015
PTTG1 pituitary tumor-transforming 1 -2.3313
SMAD5 SMAD family member 5 -2.32963
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 -2.32085
ENOPH1 enolase-phosphatase 1 -2.3101
ADGRE1 adhesion G protein-coupled receptor E1 -2.2914
RPP38 ribonuclease P/MRP 38kDa subunit -2.28385
PGRMC1 progesterone receptor membrane component 1 -2.27238
PAEP progestagen-associated endometrial protein -2.2698
TRIM28 tripartite motif containing 28 -2.2686
ENDOG endonuclease G -2.26595
TTPAL tocopherol (alpha) transfer protein-like -2.2655
MAPK9 mitogen-activated protein kinase 9 -2.26285
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -2.26255
POLR1G RNA polymerase I subunit G -2.25785
UBAC1 UBA domain containing 1 -2.2568
SP4 Sp4 transcription factor -2.24775
PRUNE1 prune exopolyphosphatase 1 -2.23827
CYB5R1 cytochrome b5 reductase 1 -2.2328
GCH1 GTP cyclohydrolase 1 -2.2272
PNPLA3 patatin-like phospholipase domain containing 3 -2.22285
BCAS3 breast carcinoma amplified sequence 3 -2.21635
LOC128966622 putative protein N-methyltransferase FAM86B2 -2.2155
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.21505
CCNF cyclin F -2.21025
PIPOX pipecolic acid oxidase -2.20205
ARF5 ADP-ribosylation factor 5 -2.2017
PARM1 prostate androgen-regulated mucin-like protein 1 -2.20065
PYCR3 pyrroline-5-carboxylate reductase 3 -2.1985
DIO3 deiodinase, iodothyronine, type III -2.1981
SH3D19 SH3 domain containing 19 -2.18852
WWOX WW domain containing oxidoreductase -2.18808
TFDP1 transcription factor Dp-1 -2.1872
FAM184A family with sequence similarity 184, member A -2.1871
HYOU1 hypoxia up-regulated 1 -2.1861
ODF2 outer dense fiber of sperm tails 2 -2.1826
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.1775
H2AX H2A.X variant histone -2.17065
KEL Kell blood group, metallo-endopeptidase -2.1563
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 -2.1536
TBC1D31 TBC1 domain family, member 31 -2.15255
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 -2.1447
MEGF9 multiple EGF-like-domains 9 -2.14175
GTF2A2 general transcription factor IIA, 2, 12kDa -2.1353
TMEM260 transmembrane protein 260 -2.13375
TMEM164 transmembrane protein 164 -2.126
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase -2.1238
TMEM161A transmembrane protein 161A -2.11223
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 -2.1102
RIMBP2 RIMS binding protein 2 -2.10615
CCNE1 cyclin E1 -2.10555
THAP11 THAP domain containing 11 -2.0994
ACTR10 actin-related protein 10 homolog (S. cerevisiae) -2.09815
CUZD1 CUB and zona pellucida-like domains 1 -2.0946
RFPL3 ret finger protein-like 3 -2.09275
LIN28A lin-28 homolog A (C. elegans) -2.0892
HEBP1 heme binding protein 1 -2.0872
CD53 CD53 molecule -2.08585
GNG7 guanine nucleotide binding protein (G protein), gamma 7 -2.08415
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.08115
TPX2 TPX2, microtubule-associated -2.07985
XK X-linked Kx blood group -2.0798
FHIT fragile histidine triad -2.0735
PYCR1 pyrroline-5-carboxylate reductase 1 -2.0704
SPHK2 sphingosine kinase 2 -2.06085
CCKBR cholecystokinin B receptor -2.05875
ECH1 enoyl CoA hydratase 1, peroxisomal -2.0587
CENPE centromere protein E, 312kDa -2.0581
RLF rearranged L-myc fusion -2.0514
KIF18B kinesin family member 18B -2.04735
NUP88 nucleoporin 88kDa -2.04557
ERCC4 excision repair cross-complementation group 4 -2.0449
FPGT fucose-1-phosphate guanylyltransferase -2.0447
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -2.04368
ANKRD55 ankyrin repeat domain 55 -2.04165
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -2.03365
GYG2 glycogenin 2 -2.03285
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific -2.0318
PXMP4 peroxisomal membrane protein 4, 24kDa -2.02555
PTGDR prostaglandin D2 receptor (DP) -2.02525
NLGN4Y neuroligin 4, Y-linked -2.0207
TSEN34 TSEN34 tRNA splicing endonuclease subunit -2.02055
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 -2.01455
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma -2.0045
PTCD1 pentatricopeptide repeat domain 1 -2.0022