| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1,1-dibutyl-2-oxohydrazine 10.74 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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84 genes differentially expressed following the CRCGN008_HEPG2_24H:I08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 5.21935 |
| MAMLD1 | mastermind-like domain containing 1 | 5.2081 |
| CHMP6 | charged multivesicular body protein 6 | 5.00995 |
| PRR15L | proline rich 15-like | 4.5275 |
| EGF | epidermal growth factor | 4.1894 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 4.12975 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.04722 |
| PLSCR1 | phospholipid scramblase 1 | 3.93837 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 3.28909 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.9559 |
| RAB31 | RAB31, member RAS oncogene family | 2.90633 |
| EVL | Enah/Vasp-like | 2.86305 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 2.70765 |
| JADE2 | jade family PHD finger 2 | 2.66075 |
| GPATCH8 | G patch domain containing 8 | 2.60462 |
| CCNF | cyclin F | 2.58332 |
| CHEK2 | checkpoint kinase 2 | 2.51345 |
| KIF18B | kinesin family member 18B | 2.51165 |
| KIF20A | kinesin family member 20A | 2.47085 |
| CHN1 | chimerin 1 | 2.4651 |
| PMM2 | phosphomannomutase 2 | 2.4296 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.39092 |
| CORO1A | coronin, actin binding protein, 1A | 2.3878 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 2.38145 |
| CYREN | cell cycle regulator of NHEJ | 2.336 |
| SULT1C4 | sulfotransferase family, cytosolic, 1C, member 4 | 2.27753 |
| HSPA4L | heat shock 70kDa protein 4-like | 2.27275 |
| MAGEA4 | melanoma antigen family A4 | 2.231 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 2.21572 |
| CD163L1 | CD163 molecule-like 1 | 2.2101 |
| PDZK1 | PDZ domain containing 1 | 2.208 |
| TBP | TATA box binding protein | 2.2055 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.19905 |
| MYOM2 | myomesin 2 | 2.18395 |
| CCNJ | cyclin J | 2.17045 |
| ELANE | elastase, neutrophil expressed | 2.16185 |
| NOC2L | nucleolar complex associated 2 homolog (S. cerevisiae) | 2.10115 |
| UBA5 | ubiquitin-like modifier activating enzyme 5 | 2.09465 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.08235 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 | 2.0361 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.0078 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | -7.73854 |
| CD320 | CD320 molecule | -5.2784 |
| ISOC1 | isochorismatase domain containing 1 | -5.1023 |
| LDHD | lactate dehydrogenase D | -4.8539 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.8182 |
| ZNF586 | zinc finger protein 586 | -4.718 |
| SMNDC1 | survival motor neuron domain containing 1 | -4.66745 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -4.48725 |
| CCNB2 | cyclin B2 | -4.22785 |
| SLC35F2 | solute carrier family 35, member F2 | -4.1641 |
| MTA1 | metastasis associated 1 | -3.67462 |
| NGRN | neugrin, neurite outgrowth associated | -3.61655 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.09275 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.86195 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.83055 |
| SESN1 | sestrin 1 | -2.72865 |
| ZNF606 | zinc finger protein 606 | -2.7094 |
| CDC25B | cell division cycle 25B | -2.6867 |
| PAEP | progestagen-associated endometrial protein | -2.67415 |
| GOLGA7 | golgin A7 | -2.65955 |
| RGS2 | regulator of G-protein signaling 2 | -2.61875 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.60895 |
| CCNB1 | cyclin B1 | -2.57035 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.52553 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -2.3808 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -2.3613 |
| ZNF419 | zinc finger protein 419 | -2.34687 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -2.3413 |
| LGI1 | leucine-rich, glioma inactivated 1 | -2.2428 |
| ZNF134 | zinc finger protein 134 | -2.2118 |
| POMZP3 | POM121 and ZP3 fusion | -2.15497 |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 | -2.15025 |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit | -2.14545 |
| ZNF211 | zinc finger protein 211 | -2.13625 |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 | -2.1255 |
| PEG10 | paternally expressed 10 | -2.12515 |
| ATP9A | ATPase, class II, type 9A | -2.1154 |
| ABR | active BCR-related | -2.11337 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -2.10815 |
| COX5A | cytochrome c oxidase subunit Va | -2.08405 |
| CCR3 | chemokine (C-C motif) receptor 3 | -2.0149 |
| FXYD7 | FXYD domain containing ion transport regulator 7 | -2.014 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa | -2.005 |
