| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1,1-dibutyl-2-oxohydrazine 5.37 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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79 genes differentially expressed following the CRCGN008_HEPG2_24H:I09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 6.3356 |
| CCDC92 | coiled-coil domain containing 92 | 5.64825 |
| GPATCH8 | G patch domain containing 8 | 5.59185 |
| TATDN2 | TatD DNase domain containing 2 | 4.95095 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 4.65813 |
| MYLK | myosin light chain kinase | 4.61955 |
| WDR7 | WD repeat domain 7 | 4.41975 |
| CDCA4 | cell division cycle associated 4 | 4.3258 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 4.26735 |
| EPN2 | epsin 2 | 4.0104 |
| HEBP1 | heme binding protein 1 | 3.68565 |
| PMM2 | phosphomannomutase 2 | 3.5469 |
| CYCS | cytochrome c, somatic | 3.50165 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 3.33455 |
| MMP2 | matrix metallopeptidase 2 | 3.03065 |
| CEP57 | centrosomal protein 57kDa | 2.78683 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 2.7165 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 | 2.62115 |
| KIF20A | kinesin family member 20A | 2.58795 |
| PTK2 | protein tyrosine kinase 2 | 2.46508 |
| MRPL15 | mitochondrial ribosomal protein L15 | 2.43505 |
| AURKB | aurora kinase B | 2.41555 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.387 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 2.3816 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 2.31175 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 2.28975 |
| RRAGA | Ras-related GTP binding A | 2.2668 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 2.2354 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 2.20045 |
| SCRN1 | secernin 1 | 2.18745 |
| ARMC1 | armadillo repeat containing 1 | 2.1514 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.14603 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.1079 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 2.07835 |
| TXNL4B | thioredoxin-like 4B | 2.07585 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 2.06615 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 2.02205 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 2.00795 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC35B1 | solute carrier family 35, member B1 | -5.72725 |
| FASTKD5 | FAST kinase domains 5 | -5.31005 |
| NISCH | nischarin | -5.2387 |
| GDF15 | growth differentiation factor 15 | -5.0 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.89085 |
| LDHD | lactate dehydrogenase D | -4.8355 |
| DERA | deoxyribose-phosphate aldolase (putative) | -4.53125 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -4.47365 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.23125 |
| GLOD4 | glyoxalase domain containing 4 | -4.10125 |
| SNX11 | sorting nexin 11 | -3.23548 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -3.16455 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -2.96255 |
| RNF167 | ring finger protein 167 | -2.94275 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -2.93813 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.8386 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.74387 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.69675 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.59715 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -2.59394 |
| TXNDC9 | thioredoxin domain containing 9 | -2.51912 |
| MAGEL2 | melanoma antigen family L2 | -2.403 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | -2.39645 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -2.2767 |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 | -2.2758 |
| NUDT19 | nudix (nucleoside diphosphate linked moiety X)-type motif 19 | -2.25615 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 | -2.2527 |
| CFP | complement factor properdin | -2.222 |
| PROS1 | protein S (alpha) | -2.20395 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -2.1541 |
| ZNF197 | zinc finger protein 197 | -2.1416 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -2.1179 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.10078 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -2.0533 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -2.04605 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.03975 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -2.0376 |
| GRB2 | growth factor receptor-bound protein 2 | -2.0372 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.03015 |
| HSPB2 | heat shock 27kDa protein 2 | -2.02575 |
| USH1C | Usher syndrome 1C (autosomal recessive, severe) | -2.01655 |
