| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1-benzyl 2-butyl phthalate 10.56 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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107 genes differentially expressed following the CRCGN008_HEPG2_24H:I14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STIMATE | STIM activating enhancer | 9.3098 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.045 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 5.0 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.804 |
| ARL4C | ADP-ribosylation factor-like 4C | 4.66395 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 4.6597 |
| CBR3 | carbonyl reductase 3 | 4.54355 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.0965 |
| PRR15L | proline rich 15-like | 3.88215 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.46838 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.43482 |
| NOSIP | nitric oxide synthase interacting protein | 3.2829 |
| INHBC | inhibin, beta C | 3.1987 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.09507 |
| MAP7 | microtubule-associated protein 7 | 3.08275 |
| KLHL9 | kelch-like family member 9 | 3.07613 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.79145 |
| TSPO | translocator protein (18kDa) | 2.71015 |
| GPATCH8 | G patch domain containing 8 | 2.64698 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 2.58035 |
| RAB31 | RAB31, member RAS oncogene family | 2.491 |
| PLSCR1 | phospholipid scramblase 1 | 2.46837 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 2.4514 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.4234 |
| XPO1 | exportin 1 | 2.3591 |
| PGAM4 | phosphoglycerate mutase family member 4 | 2.3266 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 | 2.32595 |
| EREG | epiregulin | 2.32035 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 2.3068 |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 2.2973 |
| BAMBI | BMP and activin membrane-bound inhibitor | 2.2797 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 2.27595 |
| RNASE4 | ribonuclease, RNase A family, 4 | 2.26772 |
| DOLPP1 | dolichyldiphosphatase 1 | 2.24475 |
| PDSS1 | prenyl (decaprenyl) diphosphate synthase, subunit 1 | 2.2343 |
| ARF5 | ADP-ribosylation factor 5 | 2.22115 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 2.2038 |
| COBL | cordon-bleu WH2 repeat protein | 2.174 |
| SDHAF1 | succinate dehydrogenase complex assembly factor 1 | 2.148 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 2.14195 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.1316 |
| UFM1 | ubiquitin-fold modifier 1 | 2.1196 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 | 2.1178 |
| PEX11B | peroxisomal biogenesis factor 11 beta | 2.06635 |
| ANXA10 | annexin A10 | 2.0663 |
| GMDS | GDP-mannose 4,6-dehydratase | 2.06475 |
| CERS1 | ceramide synthase 1 | 2.05325 |
| ABHD10 | abhydrolase domain containing 10 | 2.0526 |
| FADD | Fas (TNFRSF6)-associated via death domain | 2.0463 |
| PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) | 2.043 |
| LOC122526780 | uncharacterized LOC122526780 | 2.0404 |
| DHRS4 | dehydrogenase/reductase (SDR family) member 4 | 2.0385 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 2.03695 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 | 2.0348 |
| CD248 | CD248 molecule, endosialin | 2.03425 |
| PAOX | polyamine oxidase (exo-N4-amino) | 2.0294 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.02612 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 2.02165 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 2.0065 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -8.629 |
| GNAS | GNAS complex locus | -7.90276 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -6.74965 |
| UGDH | UDP-glucose 6-dehydrogenase | -5.06805 |
| GDF15 | growth differentiation factor 15 | -5.0 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.98235 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -4.5619 |
| JMJD6 | jumonji domain containing 6 | -3.9992 |
| SLC35F2 | solute carrier family 35, member F2 | -3.81245 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.8003 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -3.32875 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -2.7975 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.68577 |
| TXNDC9 | thioredoxin domain containing 9 | -2.67835 |
| TSKU | tsukushi, small leucine rich proteoglycan | -2.65945 |
| AURKA | aurora kinase A | -2.59473 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.57115 |
| RPS27L | ribosomal protein S27-like | -2.56695 |
| SQSTM1 | sequestosome 1 | -2.50455 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) | -2.47605 |
| MXRA7 | matrix-remodelling associated 7 | -2.46415 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.46065 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 | -2.44625 |
| BCAM | basal cell adhesion molecule (Lutheran blood group) | -2.32713 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -2.3211 |
| PER3 | period circadian clock 3 | -2.3081 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) | -2.2888 |
| CPAP | centrosome assembly and centriole elongation protein | -2.25795 |
| PGAM2 | phosphoglycerate mutase 2 (muscle) | -2.24265 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -2.23885 |
| GARS1 | glycyl-tRNA synthetase 1 | -2.21725 |
| DUSP28 | dual specificity phosphatase 28 | -2.2146 |
| AFAP1 | actin filament associated protein 1 | -2.1933 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -2.1588 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -2.1472 |
| UBE2V2 | ubiquitin-conjugating enzyme E2 variant 2 | -2.1367 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | -2.0957 |
| COX6C | cytochrome c oxidase subunit VIc | -2.0943 |
| C2CD3 | C2 calcium-dependent domain containing 3 | -2.09127 |
| FLRT1 | fibronectin leucine rich transmembrane protein 1 | -2.0498 |
| COX5B | cytochrome c oxidase subunit Vb | -2.04883 |
| RPN2 | ribophorin II | -2.04012 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 | -2.03345 |
| ONECUT2 | one cut homeobox 2 | -2.02795 |
| PTPRN | protein tyrosine phosphatase, receptor type, N | -2.025 |
| PHF20L1 | PHD finger protein 20-like 1 | -2.0157 |
| KBTBD2 | kelch repeat and BTB (POZ) domain containing 2 | -2.0037 |
| KLHL12 | kelch-like family member 12 | -2.00255 |
