CRCGN008_HEPG2_24H:I16 Gene Set
Genes
47 genes differentially expressed following the CRCGN008_HEPG2_24H:I16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
RPL39L
|
ribosomal protein L39-like
|
10.0
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
7.6175
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
7.19545
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
5.2176
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
5.1412
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.11805
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.9517
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.937
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.66275
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
4.48915
|
|
MYLK
|
myosin light chain kinase
|
4.4672
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
4.25167
|
|
HDGFL3
|
HDGF like 3
|
4.22647
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.95625
|
|
APBB2
|
amyloid beta (A4) precursor protein-binding, family B, member 2
|
3.78174
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.69138
|
|
PRR15L
|
proline rich 15-like
|
3.51885
|
|
NMU
|
neuromedin U
|
3.3051
|
|
PKN1
|
protein kinase N1
|
2.59505
|
|
HEBP1
|
heme binding protein 1
|
2.5595
|
|
CHN1
|
chimerin 1
|
2.5399
|
|
JADE2
|
jade family PHD finger 2
|
2.38655
|
|
GCNT1
|
glucosaminyl (N-acetyl) transferase 1, core 2
|
2.31805
|
|
CEP15
|
centrosomal protein 15
|
2.2847
|
|
ARHGEF6
|
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
|
2.2116
|
|
SENP2
|
SUMO1/sentrin/SMT3 specific peptidase 2
|
2.19135
|
|
EPHA3
|
EPH receptor A3
|
2.17278
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
2.1516
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ALAS1
|
5'-aminolevulinate synthase 1
|
-5.2424
|
|
GDF15
|
growth differentiation factor 15
|
-5.1892
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-5.14213
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.1029
|
|
SYNGAP1
|
synaptic Ras GTPase activating protein 1
|
-4.3523
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-4.3316
|
|
CCNB2
|
cyclin B2
|
-4.0901
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.9689
|
|
PGM1
|
phosphoglucomutase 1
|
-3.1108
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.91565
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.78685
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.59135
|
|
PSMB10
|
proteasome (prosome, macropain) subunit, beta type, 10
|
-2.55955
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.3371
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.3182
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.2927
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
-2.2775
|
|
ABCD1
|
ATP-binding cassette, sub-family D (ALD), member 1
|
-2.23925
|
|
ASB7
|
ankyrin repeat and SOCS box containing 7
|
-2.11565
|
