| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1-benzyl 2-butyl phthalate 0.66 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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124 genes differentially expressed following the CRCGN008_HEPG2_24H:I18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 10.0 |
| MYLK | myosin light chain kinase | 10.0 |
| EVL | Enah/Vasp-like | 5.58305 |
| AMDHD2 | amidohydrolase domain containing 2 | 5.34895 |
| PNKP | polynucleotide kinase 3'-phosphatase | 5.25915 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 5.0 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 4.94055 |
| SQOR | sulfide quinone oxidoreductase | 4.8489 |
| FZD7 | frizzled class receptor 7 | 4.84733 |
| STIMATE | STIM activating enhancer | 4.81615 |
| CBR3 | carbonyl reductase 3 | 4.5953 |
| EGF | epidermal growth factor | 4.19255 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.01688 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 3.9828 |
| SATB1 | SATB homeobox 1 | 3.94975 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.9174 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.84555 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 3.81617 |
| MAP7 | microtubule-associated protein 7 | 3.47477 |
| HDGFL3 | HDGF like 3 | 3.31564 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.30675 |
| SOCS2 | suppressor of cytokine signaling 2 | 3.28365 |
| CCNF | cyclin F | 3.28085 |
| CDK19 | cyclin-dependent kinase 19 | 3.26037 |
| ARL4C | ADP-ribosylation factor-like 4C | 3.25203 |
| MAG | myelin associated glycoprotein | 3.0396 |
| NENF | neudesin neurotrophic factor | 3.0022 |
| CHN1 | chimerin 1 | 2.89345 |
| IL17B | interleukin 17B | 2.83165 |
| SFTPB | surfactant protein B | 2.68803 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.62465 |
| MAPK4 | mitogen-activated protein kinase 4 | 2.5652 |
| EXOC2 | exocyst complex component 2 | 2.5194 |
| CBARP | CACN subunit beta associated regulatory protein | 2.50125 |
| EPHA3 | EPH receptor A3 | 2.48737 |
| KAT6A | K(lysine) acetyltransferase 6A | 2.44252 |
| BAX | BCL2-associated X protein | 2.4348 |
| KIF20A | kinesin family member 20A | 2.4094 |
| HOXD13 | homeobox D13 | 2.3057 |
| CGREF1 | cell growth regulator with EF-hand domain 1 | 2.30225 |
| TRIM11 | tripartite motif containing 11 | 2.28655 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 | 2.2565 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) | 2.23423 |
| STXBP2 | syntaxin binding protein 2 | 2.1869 |
| TEAD3 | TEA domain family member 3 | 2.10415 |
| COBL | cordon-bleu WH2 repeat protein | 2.09555 |
| OXCT2 | 3-oxoacid CoA transferase 2 | 2.09095 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 2.0882 |
| HMGB3 | high mobility group box 3 | 2.0866 |
| HOXB13 | homeobox B13 | 2.08505 |
| CNN1 | calponin 1, basic, smooth muscle | 2.078 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 2.077 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 2.0735 |
| SIGMAR1 | sigma non-opioid intracellular receptor 1 | 2.06483 |
| CATSPERH | catsper channel auxiliary subunit eta | 2.06305 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 2.06173 |
| PI15 | peptidase inhibitor 15 | 2.0499 |
| HMX1 | H6 family homeobox 1 | 2.0349 |
| SLC22A6 | solute carrier family 22 (organic anion transporter), member 6 | 2.03218 |
| DDX49 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 | 2.03172 |
| ELMO3 | engulfment and cell motility 3 | 2.0096 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 2.0062 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -6.97217 |
| ZNF586 | zinc finger protein 586 | -5.8252 |
| UGDH | UDP-glucose 6-dehydrogenase | -5.36215 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -5.0 |
| TRIB3 | tribbles pseudokinase 3 | -4.94 |
| TLCD3A | TLC domain containing 3A | -4.92475 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.8522 |
| PCNA | proliferating cell nuclear antigen | -4.81965 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | -4.81125 |
| TSPAN4 | tetraspanin 4 | -4.74622 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -4.73595 |
| VAT1 | vesicle amine transport 1 | -4.6643 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.50385 |
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | -4.36705 |
| YME1L1 | YME1-like 1 ATPase | -3.96618 |
| GNAS | GNAS complex locus | -3.82305 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.5518 |
| HMG20B | high mobility group 20B | -3.4179 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.29555 |
| CCNB2 | cyclin B2 | -3.28885 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -3.17195 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -3.08438 |
| NGRN | neugrin, neurite outgrowth associated | -3.0504 |
| SRP9 | signal recognition particle 9kDa | -2.75285 |
| ADM | adrenomedullin | -2.72655 |
| SNX11 | sorting nexin 11 | -2.69548 |
| TXNDC9 | thioredoxin domain containing 9 | -2.66258 |
| COA3 | cytochrome c oxidase assembly factor 3 | -2.5366 |
| ZNF692 | zinc finger protein 692 | -2.5339 |
| COPS4 | COP9 signalosome subunit 4 | -2.4987 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.4627 |
| ZNF514 | zinc finger protein 514 | -2.37365 |
| TRAPPC6A | trafficking protein particle complex 6A | -2.35415 |
| MPPE1 | metallophosphoesterase 1 | -2.35163 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -2.34125 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -2.3252 |
| CA14 | carbonic anhydrase XIV | -2.2985 |
| APIP | APAF1 interacting protein | -2.2777 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.25235 |
| UQCR11 | ubiquinol-cytochrome c reductase, complex III subunit XI | -2.2163 |
| SLFN12 | schlafen family member 12 | -2.2068 |
| SLIRP | SRA stem-loop interacting RNA binding protein | -2.19795 |
| ZNF273 | zinc finger protein 273 | -2.1946 |
| ZNF587 | zinc finger protein 587 | -2.18675 |
| JADE1 | jade family PHD finger 1 | -2.18365 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.17843 |
| ZNF552 | zinc finger protein 552 | -2.17485 |
| PPY | pancreatic polypeptide | -2.1683 |
| TRAF1 | TNF receptor-associated factor 1 | -2.14825 |
| ARL17B | ADP-ribosylation factor-like 17B | -2.14315 |
| TAOK1 | TAO kinase 1 | -2.1304 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -2.1232 |
| DCK | deoxycytidine kinase | -2.12315 |
| AZIN2 | antizyme inhibitor 2 | -2.11195 |
| COX16 | COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) | -2.10845 |
| TRIP4 | thyroid hormone receptor interactor 4 | -2.0821 |
| GPX3 | glutathione peroxidase 3 | -2.0794 |
| LMBR1L | limb development membrane protein 1-like | -2.0727 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -2.04562 |
| ZNF43 | zinc finger protein 43 | -2.03988 |
| MNT | MAX network transcriptional repressor | -2.0247 |
| CD1D | CD1d molecule | -2.01975 |
