| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | felbamate 2.52 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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77 genes differentially expressed following the CRCGN008_HEPG2_24H:I22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 10.0 |
| CHMP6 | charged multivesicular body protein 6 | 5.35915 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 4.94465 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.92025 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.8953 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.8758 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.85615 |
| STIMATE | STIM activating enhancer | 4.80885 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.79475 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.337 |
| SSBP2 | single-stranded DNA binding protein 2 | 4.19198 |
| TXNL4B | thioredoxin-like 4B | 4.0596 |
| NOSIP | nitric oxide synthase interacting protein | 3.96755 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.57435 |
| LOC122526780 | uncharacterized LOC122526780 | 3.52265 |
| CHN1 | chimerin 1 | 3.42145 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 3.27502 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.2492 |
| SOCS2 | suppressor of cytokine signaling 2 | 3.02413 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.9867 |
| HSPA1A | heat shock 70kDa protein 1A | 2.95785 |
| RRAGA | Ras-related GTP binding A | 2.60515 |
| KIF20A | kinesin family member 20A | 2.56175 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.51622 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 2.41245 |
| CDK20 | cyclin-dependent kinase 20 | 2.40135 |
| FOXC1 | forkhead box C1 | 2.2916 |
| SCRN1 | secernin 1 | 2.2228 |
| CADPS2 | Ca++-dependent secretion activator 2 | 2.2095 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like | 2.20235 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 2.20125 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 2.164 |
| TBP | TATA box binding protein | 2.1578 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 2.07095 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 2.0388 |
| BAMBI | BMP and activin membrane-bound inhibitor | 2.0341 |
| TMEM208 | transmembrane protein 208 | 2.02245 |
| EMC6 | ER membrane protein complex subunit 6 | 2.0025 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -5.3984 |
| SLC35F2 | solute carrier family 35, member F2 | -4.97495 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.79555 |
| FAIM | Fas apoptotic inhibitory molecule | -4.7138 |
| FASTKD5 | FAST kinase domains 5 | -4.5836 |
| GDF15 | growth differentiation factor 15 | -4.2331 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -4.0133 |
| GNAS | GNAS complex locus | -3.88794 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.71975 |
| CLTB | clathrin, light chain B | -3.39561 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.3225 |
| CCNB1 | cyclin B1 | -3.1712 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -3.13052 |
| ZW10 | zw10 kinetochore protein | -2.98545 |
| HMG20B | high mobility group 20B | -2.98532 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.91945 |
| S100A10 | S100 calcium binding protein A10 | -2.9117 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.81822 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.68715 |
| SCCPDH | saccharopine dehydrogenase (putative) | -2.60843 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.56555 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -2.56225 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.54038 |
| ATP5ME | ATP synthase membrane subunit e | -2.4534 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -2.3493 |
| FOXN2 | forkhead box N2 | -2.3468 |
| WDR11 | WD repeat domain 11 | -2.27915 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | -2.1514 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.13495 |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa | -2.1142 |
| ARHGAP25 | Rho GTPase activating protein 25 | -2.09575 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -2.09175 |
| NDUFS5 | NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) | -2.09015 |
| CES3 | carboxylesterase 3 | -2.0598 |
| THAP12 | THAP domain containing 12 | -2.02915 |
| ATRAID | all-trans retinoic acid-induced differentiation factor | -2.0291 |
| SLC67A1 | solute carrier family 67 member 1 | -2.0214 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -2.01265 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -2.002 |
