CRCGN008_HEPG2_24H:I23 Gene Set
Genes
61 genes differentially expressed following the CRCGN008_HEPG2_24H:I23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LAGE3
|
L antigen family, member 3
|
5.2189
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
5.16285
|
|
CHMP6
|
charged multivesicular body protein 6
|
5.0345
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.9021
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.53665
|
|
E2F2
|
E2F transcription factor 2
|
4.4707
|
|
ARL4C
|
ADP-ribosylation factor-like 4C
|
4.466
|
|
EPN2
|
epsin 2
|
4.31917
|
|
PRR15L
|
proline rich 15-like
|
4.1968
|
|
EGF
|
epidermal growth factor
|
4.1322
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
4.02847
|
|
TXNL4B
|
thioredoxin-like 4B
|
3.84635
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.67075
|
|
CHN1
|
chimerin 1
|
3.36305
|
|
TBXA2R
|
thromboxane A2 receptor
|
2.89845
|
|
GPATCH8
|
G patch domain containing 8
|
2.63987
|
|
MYBL2
|
v-myb avian myeloblastosis viral oncogene homolog-like 2
|
2.61475
|
|
NLGN3
|
neuroligin 3
|
2.5459
|
|
PCDHB11
|
protocadherin beta 11
|
2.51759
|
|
ZNF589
|
zinc finger protein 589
|
2.47357
|
|
EFNA4
|
ephrin-A4
|
2.3661
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.29795
|
|
STXBP2
|
syntaxin binding protein 2
|
2.2483
|
|
EVL
|
Enah/Vasp-like
|
2.2314
|
|
H2BC11
|
H2B clustered histone 11
|
2.20075
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.18795
|
|
PSIP1
|
PC4 and SFRS1 interacting protein 1
|
2.1231
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
2.1123
|
|
STK26
|
serine/threonine protein kinase 26
|
2.07005
|
|
RUFY1
|
RUN and FYVE domain containing 1
|
2.0691
|
|
USP6NL
|
USP6 N-terminal like
|
2.0666
|
|
TRIM13
|
tripartite motif containing 13
|
2.04115
|
|
AMFR
|
autocrine motility factor receptor, E3 ubiquitin protein ligase
|
2.03115
|
|
PLAG1
|
pleiomorphic adenoma gene 1
|
2.0205
|
|
ECM1
|
extracellular matrix protein 1
|
2.0096
|
|
PDE4D
|
phosphodiesterase 4D, cAMP-specific
|
2.00429
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TIMM9
|
translocase of inner mitochondrial membrane 9 homolog (yeast)
|
-5.25325
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.9485
|
|
CDC20
|
cell division cycle 20
|
-4.6933
|
|
HEATR1
|
HEAT repeat containing 1
|
-4.61315
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.54825
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.49845
|
|
COG2
|
component of oligomeric golgi complex 2
|
-4.4395
|
|
CCNB2
|
cyclin B2
|
-3.83185
|
|
CAB39
|
calcium binding protein 39
|
-3.4153
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.2228
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.0191
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.8942
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.8152
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.74073
|
|
SNX11
|
sorting nexin 11
|
-2.67368
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.50275
|
|
TSKU
|
tsukushi, small leucine rich proteoglycan
|
-2.4755
|
|
CHIC2
|
cysteine-rich hydrophobic domain 2
|
-2.4255
|
|
RNF167
|
ring finger protein 167
|
-2.4235
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.41628
|
|
CDC25B
|
cell division cycle 25B
|
-2.35655
|
|
SPRR2B
|
small proline-rich protein 2B
|
-2.2907
|
|
KIT
|
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
|
-2.26445
|
|
ERO1A
|
endoplasmic reticulum oxidoreductase 1 alpha
|
-2.0102
|
|
SPRR1A
|
small proline-rich protein 1A
|
-2.00585
|
