| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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75 genes differentially expressed following the CRCGN008_HEPG2_24H:J14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NOTCH1 | notch 1 | 5.12705 |
| NMU | neuromedin U | 5.0028 |
| ARL4C | ADP-ribosylation factor-like 4C | 4.64072 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 4.62072 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.6138 |
| ZFP36 | ZFP36 ring finger protein | 4.6085 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.5857 |
| ALDOC | aldolase C, fructose-bisphosphate | 4.5007 |
| UBQLN2 | ubiquilin 2 | 4.49245 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.44475 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.3896 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.3691 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 4.2153 |
| TBPL1 | TBP-like 1 | 3.36305 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.18605 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.1386 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.11735 |
| TBC1D31 | TBC1 domain family, member 31 | 3.07515 |
| CYB561 | cytochrome b561 | 3.07234 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 2.9567 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.94515 |
| SLC75A1 | solute carrier family 75 member 1 | 2.7406 |
| DHDDS | dehydrodolichyl diphosphate synthase | 2.6586 |
| MSH2 | mutS homolog 2 | 2.58355 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 2.516 |
| LEP | leptin | 2.43635 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.4022 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.38865 |
| KRT81 | keratin 81, type II | 2.34785 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.32888 |
| GPATCH8 | G patch domain containing 8 | 2.2982 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.25362 |
| GPD1 | glycerol-3-phosphate dehydrogenase 1 (soluble) | 2.2449 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.22385 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 2.16195 |
| PCBP3 | poly(rC) binding protein 3 | 2.12145 |
| SCRN1 | secernin 1 | 2.09605 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) | 2.08155 |
| HEBP2 | heme binding protein 2 | 2.0529 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 2.04605 |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | 2.02325 |
| TRAPPC14 | trafficking protein particle complex subunit 14 | 2.0039 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -5.45225 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -5.27585 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -5.2562 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -5.25325 |
| FASTKD5 | FAST kinase domains 5 | -5.17455 |
| MRPS2 | mitochondrial ribosomal protein S2 | -5.00925 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -4.88567 |
| LDHD | lactate dehydrogenase D | -4.7396 |
| NRIP1 | nuclear receptor interacting protein 1 | -4.6806 |
| PGM1 | phosphoglucomutase 1 | -4.58925 |
| FAIM | Fas apoptotic inhibitory molecule | -4.11575 |
| FGFR4 | fibroblast growth factor receptor 4 | -4.0699 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.89185 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.85375 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.81063 |
| CEP70 | centrosomal protein 70kDa | -2.7629 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.50675 |
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) | -2.41235 |
| TOR1A | torsin family 1, member A (torsin A) | -2.39155 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -2.3303 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | -2.32905 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.30855 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -2.22845 |
| RBM6 | RNA binding motif protein 6 | -2.17305 |
| PAEP | progestagen-associated endometrial protein | -2.16445 |
| OTUD4 | OTU deubiquitinase 4 | -2.15835 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | -2.158 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 | -2.13535 |
| PLSCR4 | phospholipid scramblase 4 | -2.1001 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 | -2.0675 |
| ATP6V1B1 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 | -2.0638 |
| ILK | integrin-linked kinase | -2.04155 |
| BCCIP | BRCA2 and CDKN1A interacting protein | -2.02625 |
