| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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121 genes differentially expressed following the CRCGN008_HEPG2_24H:J15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.415 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 5.04835 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 5.04205 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.98705 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.96885 |
| SMIM40 | small integral membrane protein 40 | 4.9419 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.81785 |
| SSBP2 | single-stranded DNA binding protein 2 | 4.2226 |
| TXNL4B | thioredoxin-like 4B | 4.19945 |
| PRR15L | proline rich 15-like | 4.07175 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.9118 |
| PMM2 | phosphomannomutase 2 | 3.8952 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 3.79325 |
| CDCA4 | cell division cycle associated 4 | 3.78125 |
| SH3D19 | SH3 domain containing 19 | 3.76205 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 3.54708 |
| JADE2 | jade family PHD finger 2 | 3.1272 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.1235 |
| GPATCH8 | G patch domain containing 8 | 3.05975 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 3.01365 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.81923 |
| RPA3 | replication protein A3, 14kDa | 2.814 |
| CYCS | cytochrome c, somatic | 2.7843 |
| HEBP1 | heme binding protein 1 | 2.55225 |
| KIF20A | kinesin family member 20A | 2.54555 |
| PRDX4 | peroxiredoxin 4 | 2.53265 |
| COPS7A | COP9 signalosome subunit 7A | 2.51095 |
| INHBE | inhibin, beta E | 2.50435 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 2.4785 |
| IFI44 | interferon-induced protein 44 | 2.39792 |
| ZBTB11 | zinc finger and BTB domain containing 11 | 2.3624 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 2.3495 |
| SLC35B1 | solute carrier family 35, member B1 | 2.3393 |
| PVRIG | poliovirus receptor related immunoglobulin domain containing | 2.31405 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 2.3105 |
| AGPAT1 | 1-acylglycerol-3-phosphate O-acyltransferase 1 | 2.2733 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.25635 |
| CHN1 | chimerin 1 | 2.2562 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 2.25595 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like | 2.2462 |
| UQCR11 | ubiquinol-cytochrome c reductase, complex III subunit XI | 2.22685 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 2.22565 |
| ACVR2B | activin A receptor, type IIB | 2.20295 |
| BST2 | bone marrow stromal cell antigen 2 | 2.1885 |
| STXBP2 | syntaxin binding protein 2 | 2.1864 |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type | 2.1723 |
| YY1AP1 | YY1 associated protein 1 | 2.1323 |
| SCRN1 | secernin 1 | 2.1314 |
| TMEM94 | transmembrane protein 94 | 2.11575 |
| ISG15 | ISG15 ubiquitin-like modifier | 2.1042 |
| MX2 | MX dynamin-like GTPase 2 | 2.09095 |
| STIL | SCL/TAL1 interrupting locus | 2.07945 |
| SLC5A1 | solute carrier family 5 (sodium/glucose cotransporter), member 1 | 2.07855 |
| LOC128125814 | uncharacterized LOC128125814 | 2.0604 |
| MZB1 | marginal zone B and B1 cell-specific protein | 2.05585 |
| MSL2 | male-specific lethal 2 homolog (Drosophila) | 2.04905 |
| MYDGF | myeloid-derived growth factor | 2.04445 |
| ADGRA2 | adhesion G protein-coupled receptor A2 | 2.04068 |
| BTN2A1 | butyrophilin, subfamily 2, member A1 | 2.03192 |
| CCDC59 | coiled-coil domain containing 59 | 2.0265 |
| TRIM39-RPP21 | TRIM39-RPP21 readthrough | 2.02435 |
| CD99 | CD99 molecule | 2.0068 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -5.9547 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -5.83515 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -5.51005 |
| UGDH | UDP-glucose 6-dehydrogenase | -5.45355 |
| THAP11 | THAP domain containing 11 | -5.41725 |
| TMEM109 | transmembrane protein 109 | -5.31565 |
| KDM3A | lysine (K)-specific demethylase 3A | -5.17205 |
| TLCD3A | TLC domain containing 3A | -5.0648 |
| PCNA | proliferating cell nuclear antigen | -4.81965 |
| FASTKD5 | FAST kinase domains 5 | -4.81735 |
| MAP7 | microtubule-associated protein 7 | -4.70822 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -4.27795 |
| TCTN1 | tectonic family member 1 | -4.255 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -3.91295 |
| GNAS | GNAS complex locus | -3.9094 |
| PRPF4 | pre-mRNA processing factor 4 | -3.84858 |
| RBM15B | RNA binding motif protein 15B | -3.7985 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -3.69127 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.59395 |
| CCNB1 | cyclin B1 | -3.36945 |
| CLIC4 | chloride intracellular channel 4 | -3.32618 |
| IFRD2 | interferon-related developmental regulator 2 | -2.72905 |
| KIF16B | kinesin family member 16B | -2.64215 |
| AOPEP | aminopeptidase O (putative) | -2.63175 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | -2.5852 |
| TXNDC9 | thioredoxin domain containing 9 | -2.575 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.449 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.41287 |
| NANS | N-acetylneuraminic acid synthase | -2.37305 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 | -2.35445 |
| TMEM115 | transmembrane protein 115 | -2.34465 |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) | -2.32225 |
| CCNJL | cyclin J-like | -2.3102 |
| SCAND1 | SCAN domain containing 1 | -2.30695 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 | -2.3065 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | -2.29425 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | -2.2828 |
| EPM2AIP1 | EPM2A (laforin) interacting protein 1 | -2.2535 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -2.23498 |
| GPN3 | GPN-loop GTPase 3 | -2.208 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | -2.20125 |
| PLXDC2 | plexin domain containing 2 | -2.1982 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.16987 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | -2.1687 |
| POM121 | POM121 transmembrane nucleoporin | -2.16535 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -2.14065 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -2.12587 |
| HAUS7 | HAUS augmin-like complex, subunit 7 | -2.11468 |
| TUFM | Tu translation elongation factor, mitochondrial | -2.1003 |
| peptide deformylase (mitochondrial) | -2.0944 | |
| PCYOX1 | prenylcysteine oxidase 1 | -2.07945 |
| PLA2G15 | phospholipase A2, group XV | -2.0743 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit | -2.05785 |
| PI15 | peptidase inhibitor 15 | -2.05255 |
| FEN1 | flap structure-specific endonuclease 1 | -2.0509 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 | -2.0242 |
| TYW2 | tRNA wybutosine-synthesizing protein 2 | -2.0174 |
| EMX2 | empty spiracles homeobox 2 | -2.0121 |
