CRCGN008_HEPG2_24H:J21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description monoethylhexylphthalate 10.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

65 genes differentially expressed following the CRCGN008_HEPG2_24H:J21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CHN1 chimerin 1 7.02575
TIAM1 T-cell lymphoma invasion and metastasis 1 6.45012
CIAO3 cytosolic iron-sulfur assembly component 3 5.9889
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 5.55235
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 5.3197
ADRB2 adrenoceptor beta 2, surface 4.8575
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 4.6178
RRAGA Ras-related GTP binding A 4.58755
ABHD6 abhydrolase domain containing 6 4.46417
SNAP25 synaptosomal-associated protein, 25kDa 4.34425
GPER1 G protein-coupled estrogen receptor 1 3.50755
PMM2 phosphomannomutase 2 3.43425
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 3.3366
CYCS cytochrome c, somatic 3.25235
PRR15L proline rich 15-like 3.24705
JADE2 jade family PHD finger 2 3.0504
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 2.9974
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.63465
GPATCH8 G patch domain containing 8 2.63375
TRIM13 tripartite motif containing 13 2.484
TLE5 TLE family member 5, transcriptional modulator 2.4765
SHISAL1 shisa like 1 2.39178
SFTPB surfactant protein B 2.3859
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.31155
GATA2 GATA binding protein 2 2.2943
PARP4 poly (ADP-ribose) polymerase family, member 4 2.28825
TNIP1 TNFAIP3 interacting protein 1 2.2359
CCDC85B coiled-coil domain containing 85B 2.19
NUCB2 nucleobindin 2 2.1644
ARID4B AT rich interactive domain 4B (RBP1-like) 2.13915
SV2B synaptic vesicle glycoprotein 2B 2.13555
INA internexin neuronal intermediate filament protein, alpha 2.09915
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 2.0809
SNCB synuclein, beta 2.04515
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 2.0357
AXIN1 axin 1 2.03515
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.03355
EPHA3 EPH receptor A3 2.01767

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -10.0
CDC20 cell division cycle 20 -5.62735
DHRS7 dehydrogenase/reductase (SDR family) member 7 -5.4822
SLC35F2 solute carrier family 35, member F2 -5.3642
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -5.2233
FASTKD5 FAST kinase domains 5 -4.28415
CCNB2 cyclin B2 -4.0119
SPAG4 sperm associated antigen 4 -3.857
ANKRD10 ankyrin repeat domain 10 -3.56225
CLTB clathrin, light chain B -3.44379
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -3.1673
ICAM3 intercellular adhesion molecule 3 -3.0115
CLIC4 chloride intracellular channel 4 -2.98455
ZMIZ1 zinc finger, MIZ-type containing 1 -2.9014
ACAA1 acetyl-CoA acyltransferase 1 -2.70055
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -2.67735
CDK6 cyclin-dependent kinase 6 -2.592
HSPA8 heat shock 70kDa protein 8 -2.54305
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -2.46565
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.4233
PROS1 protein S (alpha) -2.40905
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.13335
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -2.07343
PRPF4 pre-mRNA processing factor 4 -2.06402
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -2.0399
JPT1 Jupiter microtubule associated homolog 1 -2.02225
TSKU tsukushi, small leucine rich proteoglycan -2.00435