CRCGN008_HEPG2_24H:J22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description monoethylhexylphthalate 5.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

58 genes differentially expressed following the CRCGN008_HEPG2_24H:J22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 10.0
STIMATE STIM activating enhancer 5.59615
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 5.2021
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 5.0842
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 5.0195
PPARG peroxisome proliferator-activated receptor gamma 4.77
CIAO3 cytosolic iron-sulfur assembly component 3 4.54075
PLS1 plastin 1 4.313
CXCR4 chemokine (C-X-C motif) receptor 4 4.09597
KCNK1 potassium channel, two pore domain subfamily K, member 1 3.91847
RRAGA Ras-related GTP binding A 3.529
PRKCH protein kinase C, eta 3.4567
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 3.32145
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.27163
MAP7 microtubule-associated protein 7 3.15813
TIAM1 T-cell lymphoma invasion and metastasis 1 3.11748
KDM5A lysine (K)-specific demethylase 5A 2.98505
OASL 2'-5'-oligoadenylate synthetase-like 2.98225
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 2.88145
TBXA2R thromboxane A2 receptor 2.79979
LPAR2 lysophosphatidic acid receptor 2 2.78237
RIGI RNA sensor RIG-I 2.7471
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 2.7412
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 2.7272
RSAD2 radical S-adenosyl methionine domain containing 2 2.6983
KIF20A kinesin family member 20A 2.69465
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 2.64208
JADE2 jade family PHD finger 2 2.56293
DCP1A decapping mRNA 1A 2.5124
ISG15 ISG15 ubiquitin-like modifier 2.5021
MX1 MX dynamin-like GTPase 1 2.4907
IFI6 interferon, alpha-inducible protein 6 2.475
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 2.4398
ADAT1 adenosine deaminase, tRNA-specific 1 2.3006
ZNF589 zinc finger protein 589 2.17678
TRIM13 tripartite motif containing 13 2.1699
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 2.1626
IFI44L interferon-induced protein 44-like 2.0606
CDCA4 cell division cycle associated 4 2.04515
PIWIL2 piwi-like RNA-mediated gene silencing 2 2.03295
EVPL envoplakin 2.00825

decreased expression

Symbol Name Standardized Value
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -5.15225
LDHD lactate dehydrogenase D -5.12035
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.9549
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.70845
ZNF586 zinc finger protein 586 -4.21795
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.7319
GNAS GNAS complex locus -3.70246
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -3.59868
MAPK13 mitogen-activated protein kinase 13 -3.5677
SCAND1 SCAN domain containing 1 -2.67535
CD63 CD63 molecule -2.6572
RBM15B RNA binding motif protein 15B -2.64635
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -2.63897
RBM6 RNA binding motif protein 6 -2.26005
CASP7 caspase 7, apoptosis-related cysteine peptidase -2.2558
ACAA1 acetyl-CoA acyltransferase 1 -2.2284
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -2.1064