| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | monoethylhexylphthalate 2.5 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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51 genes differentially expressed following the CRCGN008_HEPG2_24H:J23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 5.4184 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 5.16515 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.91055 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.8958 |
| MELK | maternal embryonic leucine zipper kinase | 4.70435 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 4.5868 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.46345 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 4.23445 |
| SSBP2 | single-stranded DNA binding protein 2 | 4.01682 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 3.97985 |
| CHN1 | chimerin 1 | 3.3966 |
| PRKCH | protein kinase C, eta | 3.33075 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 3.2033 |
| PFKL | phosphofructokinase, liver | 3.16265 |
| NOSIP | nitric oxide synthase interacting protein | 3.15885 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.92357 |
| HSPA1A | heat shock 70kDa protein 1A | 2.75535 |
| ZFP36 | ZFP36 ring finger protein | 2.70285 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.65188 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.57825 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 2.5432 |
| TBC1D31 | TBC1 domain family, member 31 | 2.44375 |
| GPATCH8 | G patch domain containing 8 | 2.29463 |
| WASF3 | WAS protein family, member 3 | 2.23225 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 2.16971 |
| KAT6A | K(lysine) acetyltransferase 6A | 2.16528 |
| LAD1 | ladinin 1 | 2.12765 |
| STX1A | syntaxin 1A (brain) | 2.09995 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DERA | deoxyribose-phosphate aldolase (putative) | -5.7463 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -5.60295 |
| TSPAN4 | tetraspanin 4 | -4.77108 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.7417 |
| ILK | integrin-linked kinase | -4.59515 |
| RGS2 | regulator of G-protein signaling 2 | -3.68615 |
| CCNB2 | cyclin B2 | -3.62775 |
| GNAS | GNAS complex locus | -3.60654 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -3.38528 |
| TMCO1 | transmembrane and coiled-coil domains 1 | -2.91878 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.685 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.5899 |
| CD58 | CD58 molecule | -2.57637 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -2.5189 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.40855 |
| H2AB2 | H2A.B variant histone 2 | -2.35415 |
| PDZD2 | PDZ domain containing 2 | -2.32107 |
| APOE | apolipoprotein E | -2.17537 |
| RDH8 | retinol dehydrogenase 8 (all-trans) | -2.16535 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.13365 |
| PPP1R2C | PPP1R2C family member C | -2.1204 |
| CSAD | cysteine sulfinic acid decarboxylase | -2.03935 |
| CTSB | cathepsin B | -2.03145 |
