| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n,n-dimethyl-4-aminoazobenzene 10.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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81 genes differentially expressed following the CRCGN008_HEPG2_24H:K03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPP38 | ribonuclease P/MRP 38kDa subunit | 10.0 |
| AMDHD2 | amidohydrolase domain containing 2 | 5.60625 |
| MYLK | myosin light chain kinase | 5.47725 |
| SOCS2 | suppressor of cytokine signaling 2 | 5.3001 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.29035 |
| CBR3 | carbonyl reductase 3 | 5.10325 |
| TXNRD1 | thioredoxin reductase 1 | 5.04305 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.99135 |
| UBQLN2 | ubiquilin 2 | 4.86525 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 4.82805 |
| EPHB2 | EPH receptor B2 | 4.50063 |
| STIMATE | STIM activating enhancer | 4.4911 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.45715 |
| ADRB2 | adrenoceptor beta 2, surface | 4.45165 |
| EGF | epidermal growth factor | 4.32755 |
| NMU | neuromedin U | 4.10345 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.71978 |
| CYCS | cytochrome c, somatic | 3.6475 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 3.1726 |
| WDR7 | WD repeat domain 7 | 3.1472 |
| CHN1 | chimerin 1 | 3.09765 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 3.0729 |
| RAB31 | RAB31, member RAS oncogene family | 2.824 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.73603 |
| VGLL4 | vestigial-like family member 4 | 2.68302 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.6384 |
| KIF20A | kinesin family member 20A | 2.542 |
| ABHD4 | abhydrolase domain containing 4 | 2.534 |
| VAT1 | vesicle amine transport 1 | 2.4999 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 2.4595 |
| TXNL4B | thioredoxin-like 4B | 2.419 |
| FANCE | Fanconi anemia, complementation group E | 2.37935 |
| TBC1D31 | TBC1 domain family, member 31 | 2.31325 |
| RPGRIP1 | retinitis pigmentosa GTPase regulator interacting protein 1 | 2.2892 |
| EMILIN1 | elastin microfibril interfacer 1 | 2.28175 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 | 2.2535 |
| SNCAIP | synuclein, alpha interacting protein | 2.22915 |
| METRN | meteorin, glial cell differentiation regulator | 2.17015 |
| UGDH | UDP-glucose 6-dehydrogenase | 2.1102 |
| CBR1 | carbonyl reductase 1 | 2.10745 |
| GSR | glutathione reductase | 2.1064 |
| CDC123 | cell division cycle 123 | 2.09755 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 | 2.0163 |
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 | 2.0095 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -10.0 |
| CDC20 | cell division cycle 20 | -5.8734 |
| GOLT1B | golgi transport 1B | -5.4035 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -4.911 |
| CCNB2 | cyclin B2 | -4.38985 |
| FGFR4 | fibroblast growth factor receptor 4 | -4.04495 |
| MAPK13 | mitogen-activated protein kinase 13 | -4.01573 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.9624 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -3.60605 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.3656 |
| RECQL | RecQ helicase-like | -3.26881 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.78757 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.76737 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.75775 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.75345 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -2.58925 |
| TXNIP | thioredoxin interacting protein | -2.38762 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.35588 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -2.33795 |
| RBM34 | RNA binding motif protein 34 | -2.31063 |
| UFL1 | UFM1-specific ligase 1 | -2.2787 |
| COMMD8 | COMM domain containing 8 | -2.208 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 | -2.1908 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.19055 |
| TXNDC9 | thioredoxin domain containing 9 | -2.09987 |
| RTF2 | replication termination factor 2 | -2.093 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase | -2.0646 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -2.0441 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.03805 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -2.02575 |
| IP6K1 | inositol hexakisphosphate kinase 1 | -2.0191 |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) | -2.018 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | -2.01603 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.0111 |
| LYZL6 | lysozyme-like 6 | -2.0028 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.0015 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -2.00075 |
