| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | (2s)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid 5.04 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
67 genes differentially expressed following the CRCGN008_HEPG2_24H:K15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| E2F2 | E2F transcription factor 2 | 10.0 |
| ADRB2 | adrenoceptor beta 2, surface | 5.62965 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.43365 |
| MYLK | myosin light chain kinase | 5.0727 |
| STIMATE | STIM activating enhancer | 4.94995 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 4.92395 |
| HDGFL3 | HDGF like 3 | 4.55586 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.3309 |
| SSBP2 | single-stranded DNA binding protein 2 | 4.3111 |
| EGF | epidermal growth factor | 3.9148 |
| DHDDS | dehydrodolichyl diphosphate synthase | 3.81605 |
| JADE2 | jade family PHD finger 2 | 3.0469 |
| METRN | meteorin, glial cell differentiation regulator | 2.90835 |
| LEP | leptin | 2.86635 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.7193 |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) | 2.7015 |
| MED27 | mediator complex subunit 27 | 2.58932 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 2.3623 |
| ATG101 | autophagy related 101 | 2.2738 |
| SEC13 | SEC13 homolog (S. cerevisiae) | 2.2231 |
| LMAN2L | lectin, mannose-binding 2-like | 2.2103 |
| PES1 | pescadillo ribosomal biogenesis factor 1 | 2.18335 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.11745 |
| TBP | TATA box binding protein | 2.08745 |
| PCBP3 | poly(rC) binding protein 3 | 2.08135 |
| RAB21 | RAB21, member RAS oncogene family | 2.07705 |
| ASMTL | acetylserotonin O-methyltransferase-like | 2.06433 |
| RHOA | ras homolog family member A | 2.0529 |
| APMAP | adipocyte plasma membrane associated protein | 2.052 |
| SETMAR | SET domain and mariner transposase fusion gene | 2.0408 |
| LASP1 | LIM and SH3 protein 1 | 2.0347 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 2.00695 |
| BDNF | brain-derived neurotrophic factor | 2.00555 |
| CYB5A | cytochrome b5 type A (microsomal) | 2.00012 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -5.5316 |
| TLCD3A | TLC domain containing 3A | -4.91905 |
| CAB39 | calcium binding protein 39 | -4.7864 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.7802 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.7417 |
| GTPBP8 | GTP-binding protein 8 (putative) | -4.66665 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.66275 |
| SLC35F2 | solute carrier family 35, member F2 | -4.2793 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -3.9901 |
| FASTKD5 | FAST kinase domains 5 | -3.8542 |
| RHEB | Ras homolog enriched in brain | -3.41573 |
| GNAS | GNAS complex locus | -3.33939 |
| CCNB2 | cyclin B2 | -3.25335 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.91585 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 | -2.89335 |
| FASTK | Fas-activated serine/threonine kinase | -2.74038 |
| CCNB1 | cyclin B1 | -2.46245 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.3638 |
| ZW10 | zw10 kinetochore protein | -2.32465 |
| NDRG4 | NDRG family member 4 | -2.2894 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.27243 |
| ENGASE | endo-beta-N-acetylglucosaminidase | -2.22937 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) | -2.19405 |
| EEIG1 | estrogen-induced osteoclastogenesis regulator 1 | -2.1845 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.11735 |
| KDM7A | lysine (K)-specific demethylase 7A | -2.1144 |
| CYLD | cylindromatosis (turban tumor syndrome) | -2.09345 |
| RBM34 | RNA binding motif protein 34 | -2.09205 |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | -2.0497 |
| LRRC15 | leucine rich repeat containing 15 | -2.01285 |
| MRPS33 | mitochondrial ribosomal protein S33 | -2.008 |
| CLDND1 | claudin domain containing 1 | -2.0066 |
