| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | clofibrate 21.73 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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76 genes differentially expressed following the CRCGN008_HEPG2_24H:K19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ALDOC | aldolase C, fructose-bisphosphate | 5.5885 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.4903 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 5.31935 |
| NMU | neuromedin U | 5.1314 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 5.1244 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 5.0 |
| RPL39L | ribosomal protein L39-like | 5.0 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.8879 |
| MYLK | myosin light chain kinase | 4.8348 |
| CBR3 | carbonyl reductase 3 | 4.7671 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 4.66238 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.51735 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.3431 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.2429 |
| ANO10 | anoctamin 10 | 4.07855 |
| BZW2 | basic leucine zipper and W2 domains 2 | 3.53465 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 3.3938 |
| SLC75A1 | solute carrier family 75 member 1 | 3.2292 |
| CHN1 | chimerin 1 | 2.9211 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.90637 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 2.9061 |
| CCNF | cyclin F | 2.90315 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.83855 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.7953 |
| RRAGA | Ras-related GTP binding A | 2.7358 |
| MAP7 | microtubule-associated protein 7 | 2.66993 |
| FAIM | Fas apoptotic inhibitory molecule | 2.61075 |
| KIF5C | kinesin family member 5C | 2.48925 |
| RASL12 | RAS-like, family 12 | 2.3432 |
| EPHA3 | EPH receptor A3 | 2.32055 |
| IRS2 | insulin receptor substrate 2 | 2.2945 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.2911 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.26407 |
| MCAM | melanoma cell adhesion molecule | 2.17718 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 2.12745 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 2.127 |
| MGST2 | microsomal glutathione S-transferase 2 | 2.11225 |
| ZNF589 | zinc finger protein 589 | 2.10295 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.09145 |
| FUT3 | fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) | 2.0466 |
| PPA2 | pyrophosphatase (inorganic) 2 | 2.04045 |
| PPP1R8 | protein phosphatase 1, regulatory subunit 8 | 2.01535 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF586 | zinc finger protein 586 | -5.68325 |
| UGDH | UDP-glucose 6-dehydrogenase | -5.2683 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -5.0166 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.7545 |
| GOLT1B | golgi transport 1B | -4.2697 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -4.2502 |
| SPAG4 | sperm associated antigen 4 | -3.7325 |
| CCNB2 | cyclin B2 | -3.6674 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.40165 |
| TOR1A | torsin family 1, member A (torsin A) | -3.22032 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -3.1784 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.7571 |
| ZNF134 | zinc finger protein 134 | -2.7384 |
| SNX11 | sorting nexin 11 | -2.72977 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.72725 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.66437 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -2.5848 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.44165 |
| SIL1 | SIL1 nucleotide exchange factor | -2.39775 |
| RBM34 | RNA binding motif protein 34 | -2.31547 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -2.30998 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 | -2.2804 |
| PDS5A | PDS5 cohesin associated factor A | -2.25592 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.22445 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) | -2.19625 |
| ZNF671 | zinc finger protein 671 | -2.1499 |
| KLRC1 | killer cell lectin-like receptor subfamily C, member 1 | -2.08265 |
| SLC12A8 | solute carrier family 12, member 8 | -2.08025 |
| LAX1 | lymphocyte transmembrane adaptor 1 | -2.0775 |
| TXNDC5 | thioredoxin domain containing 5 (endoplasmic reticulum) | -2.07355 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.04585 |
| ZNF419 | zinc finger protein 419 | -2.04453 |
| COL5A1 | collagen, type V, alpha 1 | -2.0119 |
| ZG16 | zymogen granule protein 16 | -2.00755 |
