CRCGN008_HEPG2_24H:K20 Gene Set
Genes
57 genes differentially expressed following the CRCGN008_HEPG2_24H:K20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
5.66145
|
|
VGLL4
|
vestigial-like family member 4
|
5.01645
|
|
UBQLN2
|
ubiquilin 2
|
4.863
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.6959
|
|
CDC45
|
cell division cycle 45
|
4.5123
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.64605
|
|
PRKCH
|
protein kinase C, eta
|
3.6186
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.5578
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
3.0814
|
|
HEBP1
|
heme binding protein 1
|
2.9746
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.9202
|
|
TBP
|
TATA box binding protein
|
2.9157
|
|
CDCA4
|
cell division cycle associated 4
|
2.8552
|
|
CHN1
|
chimerin 1
|
2.78085
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
2.7774
|
|
NFKBIE
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
|
2.6075
|
|
ZNF589
|
zinc finger protein 589
|
2.5923
|
|
KIF20A
|
kinesin family member 20A
|
2.5348
|
|
PMM2
|
phosphomannomutase 2
|
2.50505
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.4127
|
|
APBB2
|
amyloid beta (A4) precursor protein-binding, family B, member 2
|
2.29082
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.2621
|
|
PIGP
|
phosphatidylinositol glycan anchor biosynthesis, class P
|
2.1681
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.1493
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
2.14615
|
|
PALB2
|
partner and localizer of BRCA2
|
2.12915
|
|
EPHA3
|
EPH receptor A3
|
2.07992
|
|
NMU
|
neuromedin U
|
2.02935
|
|
HELZ
|
helicase with zinc finger
|
2.0115
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-6.37265
|
|
ZNF586
|
zinc finger protein 586
|
-5.64145
|
|
GOLT1B
|
golgi transport 1B
|
-5.40205
|
|
LDHD
|
lactate dehydrogenase D
|
-5.3606
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-5.0361
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.84485
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.7943
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-4.2072
|
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
-3.92835
|
|
SNX7
|
sorting nexin 7
|
-3.8508
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-3.8163
|
|
CD320
|
CD320 molecule
|
-3.53945
|
|
LGMN
|
legumain
|
-3.45485
|
|
CCNB1
|
cyclin B1
|
-3.39305
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.3109
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-3.17375
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-3.1582
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-2.92055
|
|
EXT1
|
exostosin glycosyltransferase 1
|
-2.71042
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.62792
|
|
ECSIT
|
ECSIT signalling integrator
|
-2.5151
|
|
PDGFD
|
platelet derived growth factor D
|
-2.4878
|
|
BCKDHA
|
branched chain keto acid dehydrogenase E1, alpha polypeptide
|
-2.4394
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.10997
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.10098
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
-2.08365
|
|
SPAG4
|
sperm associated antigen 4
|
-2.0804
|
|
E2F5
|
E2F transcription factor 5, p130-binding
|
-2.02325
|
