CRCGN008_HEPG2_24H:K21 Gene Set
Genes
54 genes differentially expressed following the CRCGN008_HEPG2_24H:K21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
5.3622
|
|
CHMP6
|
charged multivesicular body protein 6
|
5.3147
|
|
JADE2
|
jade family PHD finger 2
|
5.22388
|
|
MYLK
|
myosin light chain kinase
|
5.12325
|
|
SQOR
|
sulfide quinone oxidoreductase
|
4.944
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
4.89725
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
4.0137
|
|
PRR15L
|
proline rich 15-like
|
3.6303
|
|
CYCS
|
cytochrome c, somatic
|
3.51465
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.1857
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
3.0005
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
2.8593
|
|
EPHA3
|
EPH receptor A3
|
2.84498
|
|
SFTPB
|
surfactant protein B
|
2.82197
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.80037
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.76835
|
|
CHN1
|
chimerin 1
|
2.75495
|
|
CTSL
|
cathepsin L
|
2.7122
|
|
SKIC2
|
SKI2 subunit of superkiller complex
|
2.69145
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.6436
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
2.462
|
|
HTN3
|
histatin 3
|
2.3744
|
|
PAFAH1B3
|
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
|
2.32935
|
|
HTN1
|
histatin 1
|
2.3022
|
|
ZNF589
|
zinc finger protein 589
|
2.28683
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.15252
|
|
SMR3B
|
submaxillary gland androgen regulated protein 3B
|
2.03835
|
|
SMR3A
|
submaxillary gland androgen regulated protein 3A
|
2.0359
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
ZNF586
|
zinc finger protein 586
|
-5.58675
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-5.28225
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-5.27995
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-5.0574
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-5.00145
|
|
LAP3
|
leucine aminopeptidase 3
|
-4.936
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.9253
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.81965
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.778
|
|
CD320
|
CD320 molecule
|
-4.52265
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.9235
|
|
RGS2
|
regulator of G-protein signaling 2
|
-3.45455
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.91832
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.87812
|
|
PCK1
|
phosphoenolpyruvate carboxykinase 1 (soluble)
|
-2.66515
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.6072
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.39825
|
|
RNF167
|
ring finger protein 167
|
-2.3884
|
|
SAP130
|
Sin3A-associated protein, 130kDa
|
-2.3625
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.36035
|
|
KHDC4
|
KH domain containing 4, pre-mRNA splicing factor
|
-2.1292
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
-2.12115
|
|
HLX
|
H2.0-like homeobox
|
-2.10915
|
|
SYNGAP1
|
synaptic Ras GTPase activating protein 1
|
-2.06938
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.03325
|
