CRCGN008_HEPG2_24H:L01 Gene Set
Genes
53 genes differentially expressed following the CRCGN008_HEPG2_24H:L01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CYCS
|
cytochrome c, somatic
|
5.9624
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
5.0737
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.00455
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.8752
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
4.41117
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.263
|
|
STXBP1
|
syntaxin binding protein 1
|
4.0979
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.32037
|
|
MAP7
|
microtubule-associated protein 7
|
3.29287
|
|
EGF
|
epidermal growth factor
|
3.2026
|
|
VGLL4
|
vestigial-like family member 4
|
3.09162
|
|
GPATCH8
|
G patch domain containing 8
|
2.95248
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.76305
|
|
PGAM4
|
phosphoglycerate mutase family member 4
|
2.4226
|
|
WASF3
|
WAS protein family, member 3
|
2.39755
|
|
TASOR
|
transcription activation suppressor
|
2.30343
|
|
S100A7
|
S100 calcium binding protein A7
|
2.29775
|
|
TBP
|
TATA box binding protein
|
2.2867
|
|
SPDL1
|
spindle apparatus coiled-coil protein 1
|
2.253
|
|
SPG11
|
spastic paraplegia 11 (autosomal recessive)
|
2.2156
|
|
NOC3L
|
nucleolar complex associated 3 homolog (S. cerevisiae)
|
2.1414
|
|
CLCA2
|
chloride channel accessory 2
|
2.1262
|
|
TLR4
|
toll-like receptor 4
|
2.11595
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
2.06865
|
|
ELP5
|
elongator acetyltransferase complex subunit 5
|
2.0588
|
|
CDK8
|
cyclin-dependent kinase 8
|
2.0226
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
2.0021
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-10.0
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.96845
|
|
ZNF586
|
zinc finger protein 586
|
-5.2041
|
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
-5.02415
|
|
CDC20
|
cell division cycle 20
|
-5.0
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.95415
|
|
VAT1
|
vesicle amine transport 1
|
-4.90835
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-4.3821
|
|
DCK
|
deoxycytidine kinase
|
-3.812
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-3.68215
|
|
CCNB1
|
cyclin B1
|
-2.9224
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.62663
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.51842
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.3207
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.2163
|
|
FGF16
|
fibroblast growth factor 16
|
-2.19425
|
|
ART4
|
ADP-ribosyltransferase 4 (Dombrock blood group)
|
-2.17415
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.16542
|
|
GNG10
|
guanine nucleotide binding protein (G protein), gamma 10
|
-2.1606
|
|
KLHL25
|
kelch-like family member 25
|
-2.1233
|
|
STAB2
|
stabilin 2
|
-2.11685
|
|
HS3ST2
|
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
|
-2.08365
|
|
H1-3
|
H1.3 linker histone, cluster member
|
-2.02875
|
|
RBM34
|
RNA binding motif protein 34
|
-2.0269
|
|
RASAL1
|
RAS protein activator like 1 (GAP1 like)
|
-2.0244
|
|
GNRH2
|
gonadotropin-releasing hormone 2
|
-2.0239
|
