| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | methyl methacrylate 19.5 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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67 genes differentially expressed following the CRCGN008_HEPG2_24H:L02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CCL2 | chemokine (C-C motif) ligand 2 | 6.15115 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.65655 |
| EPHB2 | EPH receptor B2 | 5.261 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.23285 |
| ADRB2 | adrenoceptor beta 2, surface | 5.21265 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 5.20865 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 5.20155 |
| PRR15L | proline rich 15-like | 5.13005 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.77995 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.42495 |
| INTS3 | integrator complex subunit 3 | 4.20475 |
| CHN1 | chimerin 1 | 3.9988 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.71065 |
| PLSCR1 | phospholipid scramblase 1 | 3.59452 |
| GATA3 | GATA binding protein 3 | 3.34683 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 3.26555 |
| TBP | TATA box binding protein | 3.0748 |
| ABHD4 | abhydrolase domain containing 4 | 3.04235 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.99665 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.79415 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | 2.43817 |
| SLC75A1 | solute carrier family 75 member 1 | 2.4074 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 2.37598 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 2.21205 |
| SIAH2 | siah E3 ubiquitin protein ligase 2 | 2.1506 |
| TRH | thyrotropin-releasing hormone | 2.1471 |
| TFF3 | trefoil factor 3 (intestinal) | 2.1453 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.1385 |
| CDK19 | cyclin-dependent kinase 19 | 2.06255 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.0508 |
| E2F2 | E2F transcription factor 2 | 2.0399 |
| METRN | meteorin, glial cell differentiation regulator | 2.0288 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.0207 |
| IZUMO4 | IZUMO family member 4 | 2.0009 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -5.49765 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -5.3068 |
| UGDH | UDP-glucose 6-dehydrogenase | -5.2045 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -5.1608 |
| SCAND1 | SCAN domain containing 1 | -4.8126 |
| PCNA | proliferating cell nuclear antigen | -4.77245 |
| CAB39 | calcium binding protein 39 | -4.7659 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.99625 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -3.7799 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -3.65305 |
| GNAS | GNAS complex locus | -3.58376 |
| CCNB1 | cyclin B1 | -3.4783 |
| CLIC4 | chloride intracellular channel 4 | -2.99697 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.84175 |
| NLRP4 | NLR family, pyrin domain containing 4 | -2.8029 |
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | -2.653 |
| HSPA8 | heat shock 70kDa protein 8 | -2.62057 |
| SMC3 | structural maintenance of chromosomes 3 | -2.53125 |
| CDC25B | cell division cycle 25B | -2.5257 |
| CCP110 | centriolar coiled coil protein 110kDa | -2.5075 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.50205 |
| NVL | nuclear VCP-like | -2.49815 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.45135 |
| ISCU | iron-sulfur cluster assembly enzyme | -2.376 |
| FBLN2 | fibulin 2 | -2.3755 |
| NOL4 | nucleolar protein 4 | -2.2304 |
| RBM6 | RNA binding motif protein 6 | -2.1991 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) | -2.0977 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -2.07385 |
| BRD3 | bromodomain containing 3 | -2.05515 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | -2.0357 |
| KIF16B | kinesin family member 16B | -2.02605 |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide | -2.0095 |
