| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | methyl methacrylate 1.22 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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59 genes differentially expressed following the CRCGN008_HEPG2_24H:L06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 5.62485 |
| UBQLN2 | ubiquilin 2 | 5.5658 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 5.2983 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.19715 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 4.60675 |
| CHN1 | chimerin 1 | 4.40015 |
| SSBP2 | single-stranded DNA binding protein 2 | 4.13485 |
| PRR15L | proline rich 15-like | 4.111 |
| ALDOC | aldolase C, fructose-bisphosphate | 3.9948 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.97177 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 3.70405 |
| VGLL4 | vestigial-like family member 4 | 3.62608 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 3.38503 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 3.35105 |
| GATA3 | GATA binding protein 3 | 3.22527 |
| HEBP1 | heme binding protein 1 | 2.88335 |
| GPATCH8 | G patch domain containing 8 | 2.79885 |
| TBP | TATA box binding protein | 2.7582 |
| LMBRD1 | LMBR1 domain containing 1 | 2.68185 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) | 2.61627 |
| CCNF | cyclin F | 2.37818 |
| ICAM1 | intercellular adhesion molecule 1 | 2.31703 |
| SPCS1 | signal peptidase complex subunit 1 homolog (S. cerevisiae) | 2.22935 |
| MAGEH1 | melanoma antigen family H1 | 2.22035 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.19055 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 2.1331 |
| TCIM | transcriptional and immune response regulator | 2.0688 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 2.02865 |
| MKRN2 | makorin ring finger protein 2 | 2.0037 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNM1L | dynamin 1-like | -10.0 |
| LDHD | lactate dehydrogenase D | -10.0 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.9743 |
| CDC25B | cell division cycle 25B | -4.65345 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.5989 |
| TUBB6 | tubulin, beta 6 class V | -4.2697 |
| TLCD3A | TLC domain containing 3A | -3.7063 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -3.56887 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.41225 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -3.25227 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.22555 |
| HSPA8 | heat shock 70kDa protein 8 | -3.14047 |
| HMG20B | high mobility group 20B | -3.08795 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.0622 |
| WASHC4 | WASH complex subunit 4 | -2.88893 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.51465 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -2.392 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.23395 |
| RSU1 | Ras suppressor protein 1 | -2.22355 |
| POLR2J3 | polymerase (RNA) II (DNA directed) polypeptide J3 | -2.18867 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.1756 |
| TXNRD1 | thioredoxin reductase 1 | -2.1502 |
| TATDN2 | TatD DNase domain containing 2 | -2.14435 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | -2.10675 |
| OGDHL | oxoglutarate dehydrogenase-like | -2.1 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | -2.0774 |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) | -2.0712 |
| VTI1B | vesicle transport through interaction with t-SNAREs 1B | -2.06805 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -2.05105 |
| IL17B | interleukin 17B | -2.0359 |