CRCGN008_HEPG2_24H:L07 Gene Set
Genes
51 genes differentially expressed following the CRCGN008_HEPG2_24H:L07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
5.91385
|
|
LCN2
|
lipocalin 2
|
5.60885
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
5.2735
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
4.16755
|
|
CHN1
|
chimerin 1
|
3.87015
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.80975
|
|
EPHA3
|
EPH receptor A3
|
3.72908
|
|
PRKCH
|
protein kinase C, eta
|
3.7242
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
3.34855
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.81367
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.72878
|
|
RRAGA
|
Ras-related GTP binding A
|
2.64545
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.5314
|
|
GPATCH8
|
G patch domain containing 8
|
2.52525
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
2.47253
|
|
TBP
|
TATA box binding protein
|
2.41315
|
|
TBPL1
|
TBP-like 1
|
2.2973
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.2957
|
|
PRKAG1
|
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
|
2.1744
|
|
AXIN1
|
axin 1
|
2.16585
|
|
SDAD1
|
SDA1 domain containing 1
|
2.1513
|
|
RPL34
|
ribosomal protein L34
|
2.10135
|
|
PARP2
|
poly (ADP-ribose) polymerase 2
|
2.0868
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
2.06885
|
|
RPS27A
|
ribosomal protein S27a
|
2.0665
|
|
PPP1R8
|
protein phosphatase 1, regulatory subunit 8
|
2.04985
|
|
RPL7A
|
ribosomal protein L7a
|
2.0351
|
|
MRPS22
|
mitochondrial ribosomal protein S22
|
2.0213
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-5.04835
|
|
CDC20
|
cell division cycle 20
|
-4.6933
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.60205
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-4.50513
|
|
STUB1
|
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
|
-4.4691
|
|
CD320
|
CD320 molecule
|
-4.38015
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.35575
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-3.93385
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-3.9116
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.54175
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-3.1231
|
|
CCNB1
|
cyclin B1
|
-3.06425
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.67938
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.562
|
|
RHBDL1
|
rhomboid, veinlet-like 1 (Drosophila)
|
-2.3718
|
|
TGFBR3
|
transforming growth factor, beta receptor III
|
-2.2606
|
|
VASP
|
vasodilator-stimulated phosphoprotein
|
-2.2547
|
|
MYBL1
|
v-myb avian myeloblastosis viral oncogene homolog-like 1
|
-2.2516
|
|
KAT2B
|
K(lysine) acetyltransferase 2B
|
-2.24065
|
|
EPB41L3
|
erythrocyte membrane protein band 4.1-like 3
|
-2.21353
|
|
BCL11A
|
B-cell CLL/lymphoma 11A (zinc finger protein)
|
-2.04547
|
|
GET1
|
guided entry of tail-anchored proteins factor 1
|
-2.026
|
|
MS4A1
|
membrane-spanning 4-domains, subfamily A, member 1
|
-2.0051
|
