CRCGN008_HEPG2_24H:L09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acetamide 10.4 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

35 genes differentially expressed following the CRCGN008_HEPG2_24H:L09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 5.4038
UBQLN2 ubiquilin 2 5.08075
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.82595
NR1H2 nuclear receptor subfamily 1, group H, member 2 4.7907
NMU neuromedin U 4.5825
PPARG peroxisome proliferator-activated receptor gamma 4.53525
CHN1 chimerin 1 4.0722
SSBP2 single-stranded DNA binding protein 2 3.94182
CCNF cyclin F 3.12422
WDR7 WD repeat domain 7 3.06275
GATA2 GATA binding protein 2 2.8984
STXBP2 syntaxin binding protein 2 2.83725
GSTZ1 glutathione S-transferase zeta 1 2.6808
HEBP1 heme binding protein 1 2.52195
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 2.42605
IGHMBP2 immunoglobulin mu binding protein 2 2.41245
TBP TATA box binding protein 2.323
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.08315
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 2.04605

decreased expression

Symbol Name Standardized Value
CCNB2 cyclin B2 -4.8413
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.6851
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -4.6354
YME1L1 YME1-like 1 ATPase -4.21958
GET1 guided entry of tail-anchored proteins factor 1 -3.60525
OXA1L oxidase (cytochrome c) assembly 1-like -3.1275
SPAG4 sperm associated antigen 4 -3.06005
STAT1 signal transducer and activator of transcription 1, 91kDa -2.79791
CCNB1 cyclin B1 -2.7606
SENP6 SUMO1/sentrin specific peptidase 6 -2.552
FHL2 four and a half LIM domains 2 -2.4147
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -2.30255
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.23562
C5 complement component 5 -2.19525
REC8 REC8 meiotic recombination protein -2.08225
PDIA5 protein disulfide isomerase family A, member 5 -2.0584