CRCGN008_HEPG2_24H:L10 Gene Set
Genes
42 genes differentially expressed following the CRCGN008_HEPG2_24H:L10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
5.39455
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.79255
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.70475
|
|
STK10
|
serine/threonine kinase 10
|
4.4979
|
|
TXNL4B
|
thioredoxin-like 4B
|
4.23715
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.09155
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.085
|
|
EGF
|
epidermal growth factor
|
3.74745
|
|
POLG2
|
polymerase (DNA directed), gamma 2, accessory subunit
|
3.07328
|
|
CCNF
|
cyclin F
|
2.92222
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
2.87845
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.79615
|
|
CCNA1
|
cyclin A1
|
2.39045
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
2.28
|
|
RAB31
|
RAB31, member RAS oncogene family
|
2.27112
|
|
HOXC11
|
homeobox C11
|
2.2273
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.1646
|
|
JADE2
|
jade family PHD finger 2
|
2.1605
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.12455
|
|
NKAPD1
|
NKAP domain containing 1
|
2.1208
|
|
FARP2
|
FERM, RhoGEF and pleckstrin domain protein 2
|
2.07105
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
2.0272
|
|
ABHD4
|
abhydrolase domain containing 4
|
2.0227
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-6.1805
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.33725
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.4696
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-4.01338
|
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
-3.82575
|
|
APIP
|
APAF1 interacting protein
|
-3.27455
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-3.1571
|
|
CCNB2
|
cyclin B2
|
-3.0982
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-3.0084
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.99013
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.9403
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.71973
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.6965
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.6215
|
|
NAT10
|
N-acetyltransferase 10 (GCN5-related)
|
-2.40855
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.3995
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.3069
|
|
GLOD4
|
glyoxalase domain containing 4
|
-2.20015
|
|
MAFB
|
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
|
-2.00595
|
