| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | acetamide 2.6 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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72 genes differentially expressed following the CRCGN008_HEPG2_24H:L11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 10.0 |
| CBR3 | carbonyl reductase 3 | 9.51125 |
| CYCS | cytochrome c, somatic | 6.5031 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.10435 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 5.037 |
| STK10 | serine/threonine kinase 10 | 4.83107 |
| EPHA3 | EPH receptor A3 | 4.28383 |
| EPN2 | epsin 2 | 4.2214 |
| EGF | epidermal growth factor | 3.9838 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.82115 |
| MAP7 | microtubule-associated protein 7 | 3.501 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) | 3.052 |
| CHN1 | chimerin 1 | 2.7737 |
| PLSCR3 | phospholipid scramblase 3 | 2.7543 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.65575 |
| TBP | TATA box binding protein | 2.638 |
| PMM2 | phosphomannomutase 2 | 2.6061 |
| KLHL9 | kelch-like family member 9 | 2.60027 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.48045 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.47505 |
| TLR4 | toll-like receptor 4 | 2.4527 |
| MGLL | monoglyceride lipase | 2.3881 |
| CLIC3 | chloride intracellular channel 3 | 2.37375 |
| TENT4A | terminal nucleotidyltransferase 4A | 2.34325 |
| GRB14 | growth factor receptor-bound protein 14 | 2.3268 |
| SIRT3 | sirtuin 3 | 2.2678 |
| DEFB1 | defensin, beta 1 | 2.2636 |
| TXNL4B | thioredoxin-like 4B | 2.23005 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 | 2.21695 |
| SLC67A2 | solute carrier family 67 member 2 | 2.1884 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | 2.17178 |
| SRGN | serglycin | 2.13667 |
| CRIPT | cysteine-rich PDZ-binding protein | 2.1269 |
| MB | myoglobin | 2.10085 |
| MPC1 | mitochondrial pyruvate carrier 1 | 2.09915 |
| AXIN1 | axin 1 | 2.08255 |
| UEVLD | UEV and lactate/malate dehyrogenase domains | 2.0705 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | 2.06845 |
| SEC61B | Sec61 beta subunit | 2.06485 |
| TMEM267 | transmembrane protein 267 | 2.04605 |
| JADE3 | jade family PHD finger 3 | 2.02995 |
| CD151 | CD151 molecule (Raph blood group) | 2.02625 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 2.026 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -10.0 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -6.49785 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -5.74945 |
| TLCD3A | TLC domain containing 3A | -5.3773 |
| LDHD | lactate dehydrogenase D | -4.9258 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.78895 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.66275 |
| CCDC86 | coiled-coil domain containing 86 | -4.30645 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -3.97025 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -3.60575 |
| GNAS | GNAS complex locus | -3.547 |
| CCNB2 | cyclin B2 | -3.3725 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -2.92755 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -2.8565 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) | -2.6 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.4935 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 | -2.376 |
| DCK | deoxycytidine kinase | -2.3093 |
| CCNB1 | cyclin B1 | -2.2946 |
| LCT | lactase | -2.2902 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -2.2633 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 | -2.24155 |
| LOX | lysyl oxidase | -2.13208 |
| RNPEP | arginyl aminopeptidase (aminopeptidase B) | -2.12777 |
| MMP11 | matrix metallopeptidase 11 | -2.12033 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -2.11385 |
| RNF167 | ring finger protein 167 | -2.0855 |
| TTC31 | tetratricopeptide repeat domain 31 | -2.0786 |
| PTCD3 | pentatricopeptide repeat domain 3 | -2.0616 |
