CRCGN008_HEPG2_24H:L16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzo(a)pyrene 2.52 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

944 genes differentially expressed following the CRCGN008_HEPG2_24H:L16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 10.0
BLCAP bladder cancer associated protein 10.0
LRP10 low density lipoprotein receptor-related protein 10 10.0
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
INPP1 inositol polyphosphate-1-phosphatase 10.0
ABHD4 abhydrolase domain containing 4 10.0
DUSP14 dual specificity phosphatase 14 8.52915
DDB2 damage-specific DNA binding protein 2, 48kDa 8.5269
MICALL1 MICAL-like 1 7.99685
TXNRD1 thioredoxin reductase 1 7.99055
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 7.7009
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 7.62
TUBB6 tubulin, beta 6 class V 7.57735
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 7.1681
CCDC92 coiled-coil domain containing 92 6.97685
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 6.81395
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 6.6357
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 6.4179
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 6.4087
KEAP1 kelch-like ECH-associated protein 1 6.34395
PRKCD protein kinase C, delta 6.20445
GPC1 glypican 1 5.9931
RALGDS ral guanine nucleotide dissociation stimulator 5.81575
FOXJ3 forkhead box J3 5.7661
TIMP2 TIMP metallopeptidase inhibitor 2 5.6814
LSR lipolysis stimulated lipoprotein receptor 5.62645
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 5.5842
EGF epidermal growth factor 5.51905
NOTCH1 notch 1 5.46555
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 5.41045
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 5.36977
MOK MOK protein kinase 5.22525
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 5.142
ALAS1 5'-aminolevulinate synthase 1 4.99575
IGFBP3 insulin-like growth factor binding protein 3 4.88622
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 4.84138
ASCC3 activating signal cointegrator 1 complex subunit 3 4.7704
ADGRG1 adhesion G protein-coupled receptor G1 4.58033
KIFBP kinesin family binding protein 4.5405
SQOR sulfide quinone oxidoreductase 4.5369
BDH1 3-hydroxybutyrate dehydrogenase, type 1 4.4112
SCPEP1 serine carboxypeptidase 1 4.34285
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 4.27365
IER3 immediate early response 3 4.2289
RPL39L ribosomal protein L39-like 4.22165
TESK1 testis-specific kinase 1 4.18135
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4.17695
FOSL1 FOS-like antigen 1 4.1766
CBR1 carbonyl reductase 1 4.14995
DHRS7 dehydrogenase/reductase (SDR family) member 7 4.1293
TERF2IP telomeric repeat binding factor 2, interacting protein 4.0348
STXBP2 syntaxin binding protein 2 3.9914
VAT1 vesicle amine transport 1 3.94295
HMOX1 heme oxygenase 1 3.876
XPC xeroderma pigmentosum, complementation group C 3.8712
ATG9A autophagy related 9A 3.8064
NIT1 nitrilase 1 3.79975
PNKP polynucleotide kinase 3'-phosphatase 3.77935
ZNF79 zinc finger protein 79 3.7786
BAX BCL2-associated X protein 3.77367
MAPK13 mitogen-activated protein kinase 13 3.77288
CCDC86 coiled-coil domain containing 86 3.7545
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 3.67825
CBR3 carbonyl reductase 3 3.62165
TRIM16 tripartite motif containing 16 3.61565
CCND3 cyclin D3 3.60125
CASC3 cancer susceptibility candidate 3 3.5721
CEL carboxyl ester lipase 3.546
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 3.52905
SMAD3 SMAD family member 3 3.51809
COL17A1 collagen, type XVII, alpha 1 3.5161
KCNK1 potassium channel, two pore domain subfamily K, member 1 3.49685
POMZP3 POM121 and ZP3 fusion 3.48715
TNIP1 TNFAIP3 interacting protein 1 3.48235
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 3.45395
FPGS folylpolyglutamate synthase 3.424
ZNF212 zinc finger protein 212 3.42365
RALB v-ral simian leukemia viral oncogene homolog B 3.3672
GPN2 GPN-loop GTPase 2 3.33435
MAP7D1 MAP7 domain containing 1 3.3196
RAP1GAP RAP1 GTPase activating protein 3.31785
DNM1L dynamin 1-like 3.30325
CREG1 cellular repressor of E1A-stimulated genes 1 3.2646
FDXR ferredoxin reductase 3.2468
GCLC glutamate-cysteine ligase, catalytic subunit 3.21015
TIGAR TP53 induced glycolysis regulatory phosphatase 3.20085
MINDY1 MINDY lysine 48 deubiquitinase 1 3.1769
DDR1 discoidin domain receptor tyrosine kinase 1 3.17014
HSPA1A heat shock 70kDa protein 1A 3.16115
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 3.14545
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 3.14045
THSD1 thrombospondin, type I, domain containing 1 3.13565
TRIM32 tripartite motif containing 32 3.1352
CARMIL1 capping protein regulator and myosin 1 linker 1 3.12975
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 3.12775
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 3.11998
FASN fatty acid synthase 3.11468
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 3.10658
MVP major vault protein 3.1061
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 3.0982
COL7A1 collagen, type VII, alpha 1 3.0939
CDK5RAP1 CDK5 regulatory subunit associated protein 1 3.09215
FRS2 fibroblast growth factor receptor substrate 2 3.0737
FBRS fibrosin 3.0643
ROGDI rogdi homolog (Drosophila) 3.05045
H2BC21 H2B clustered histone 21 3.0399
TSKU tsukushi, small leucine rich proteoglycan 3.0396
PRKCQ protein kinase C, theta 2.98725
METRN meteorin, glial cell differentiation regulator 2.98495
STOM stomatin 2.97618
SHB Src homology 2 domain containing adaptor protein B 2.9667
ORAI3 ORAI calcium release-activated calcium modulator 3 2.95285
SSBP2 single-stranded DNA binding protein 2 2.92373
TRIT1 tRNA isopentenyltransferase 1 2.9227
ELAC2 elaC ribonuclease Z 2 2.90685
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 2.89905
CNPY3 canopy FGF signaling regulator 3 2.8895
KDM3A lysine (K)-specific demethylase 3A 2.88915
KDM5C lysine (K)-specific demethylase 5C 2.875
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 2.8718
TOR1A torsin family 1, member A (torsin A) 2.8591
TBPL1 TBP-like 1 2.84135
KIF20A kinesin family member 20A 2.83355
PDLIM7 PDZ and LIM domain 7 (enigma) 2.82917
OSGIN1 oxidative stress induced growth inhibitor 1 2.8265
NSUN3 NOP2/Sun domain family, member 3 2.82535
TP53I3 tumor protein p53 inducible protein 3 2.8171
GAA glucosidase, alpha; acid 2.7915
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 2.78965
DUSP6 dual specificity phosphatase 6 2.78688
SKIC2 SKI2 subunit of superkiller complex 2.7784
GABARAPL1 GABA(A) receptor-associated protein like 1 2.76827
STX4 syntaxin 4 2.7653
TOMM34 translocase of outer mitochondrial membrane 34 2.76335
MCOLN1 mucolipin 1 2.75965
RAB8B RAB8B, member RAS oncogene family 2.74555
PHLDA3 pleckstrin homology-like domain, family A, member 3 2.741
GADD45A growth arrest and DNA-damage-inducible, alpha 2.72405
PIAS3 protein inhibitor of activated STAT, 3 2.71735
PRSS8 protease, serine, 8 2.7164
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 2.70705
ADRB2 adrenoceptor beta 2, surface 2.7047
UBAP1 ubiquitin associated protein 1 2.7025
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 2.688
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 2.67645
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 2.6717
ADGRE5 adhesion G protein-coupled receptor E5 2.6656
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 2.66515
LOXL1 lysyl oxidase-like 1 2.6618
TICAM1 toll-like receptor adaptor molecule 1 2.6597
CSRNP2 cysteine-serine-rich nuclear protein 2 2.6502
TSEN2 TSEN2 tRNA splicing endonuclease subunit 2.64565
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 2.6386
ANGPTL4 angiopoietin-like 4 2.62655
ATG2A autophagy related 2A 2.62615
JUP junction plakoglobin 2.62555
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.62505
BPNT2 3'(2'), 5'-bisphosphate nucleotidase 2 2.6168
ZNHIT2 zinc finger, HIT-type containing 2 2.61585
FLNA filamin A, alpha 2.60162
RABGGTA Rab geranylgeranyltransferase, alpha subunit 2.60035
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.59695
UBA1 ubiquitin-like modifier activating enzyme 1 2.5952
MARCHF5 membrane associated ring-CH-type finger 5 2.59325
RCOR3 REST corepressor 3 2.5897
UBE2A ubiquitin-conjugating enzyme E2A 2.5819
AAR2 AAR2 splicing factor homolog (S. cerevisiae) 2.5716
RGS20 regulator of G-protein signaling 20 2.5675
YAP1 Yes-associated protein 1 2.5665
SART1 squamous cell carcinoma antigen recognized by T cells 2.5626
IL4R interleukin 4 receptor 2.55775
PHKG2 phosphorylase kinase, gamma 2 (testis) 2.5577
BTG2 BTG family, member 2 2.54682
THAP10 THAP domain containing 10 2.54215
LAMB3 laminin, beta 3 2.5417
SURF2 surfeit 2 2.5323
ZNF282 zinc finger protein 282 2.52955
TRIM68 tripartite motif containing 68 2.5137
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 2.5132
TRIM8 tripartite motif containing 8 2.5083
CDK9 cyclin-dependent kinase 9 2.50805
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.5074
SETD1A SET domain containing 1A 2.49975
TRAFD1 TRAF-type zinc finger domain containing 1 2.49272
TKTL1 transketolase-like 1 2.48453
PAGE4 P antigen family, member 4 (prostate associated) 2.47755
HSPB1 heat shock 27kDa protein 1 2.47715
RAB38 RAB38, member RAS oncogene family 2.47445
GATA2 GATA binding protein 2 2.47175
MNT MAX network transcriptional repressor 2.4712
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 2.46915
GCLM glutamate-cysteine ligase, modifier subunit 2.46445
NINJ1 ninjurin 1 2.4623
CNKSR1 connector enhancer of kinase suppressor of Ras 1 2.46135
PRKD2 protein kinase D2 2.46057
RNF4 ring finger protein 4 2.4514
FOXO3 forkhead box O3 2.44852
BCL9 B-cell CLL/lymphoma 9 2.44655
CES1 carboxylesterase 1 2.446
GRN granulin 2.43892
PLS1 plastin 1 2.4317
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 2.4301
ST18 suppression of tumorigenicity 18, zinc finger 2.42765
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 2.42385
RIPK4 receptor-interacting serine-threonine kinase 4 2.41715
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 2.417
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.41657
SGSH N-sulfoglucosamine sulfohydrolase 2.41427
FBXL12 F-box and leucine-rich repeat protein 12 2.413
EVL Enah/Vasp-like 2.41175
KHDC4 KH domain containing 4, pre-mRNA splicing factor 2.4012
RIN1 Ras and Rab interactor 1 2.4007
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.3958
SFTPB surfactant protein B 2.39565
GSTZ1 glutathione S-transferase zeta 1 2.3901
PTGES prostaglandin E synthase 2.38982
MOGAT1 monoacylglycerol O-acyltransferase 1 2.3889
ANKRD10 ankyrin repeat domain 10 2.3778
FABP6 fatty acid binding protein 6, ileal 2.37675
LRRC41 leucine rich repeat containing 41 2.37347
SBNO1 strawberry notch homolog 1 (Drosophila) 2.3713
BAG3 BCL2-associated athanogene 3 2.3685
RGL2 ral guanine nucleotide dissociation stimulator-like 2 2.3647
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 2.3629
BRMS1L breast cancer metastasis-suppressor 1-like 2.3611
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 2.3597
KLHL36 kelch-like family member 36 2.3581
YEATS2 YEATS domain containing 2 2.35355
JADE2 jade family PHD finger 2 2.3468
ETV6 ets variant 6 2.34135
PDCD10 programmed cell death 10 2.3394
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 2.3341
AKR1C3 aldo-keto reductase family 1, member C3 2.3315
BECN1 beclin 1, autophagy related 2.32518
KRT7 keratin 7, type II 2.3234
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 2.32283
CHD8 chromodomain helicase DNA binding protein 8 2.32195
SMC1A structural maintenance of chromosomes 1A 2.32148
EYA4 EYA transcriptional coactivator and phosphatase 4 2.3184
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.31395
EHBP1L1 EH domain binding protein 1-like 1 2.31077
ELMO2 engulfment and cell motility 2 2.30368
RIOK3 RIO kinase 3 2.30088
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 2.29625
SREBF1 sterol regulatory element binding transcription factor 1 2.2919
GPBP1L1 GC-rich promoter binding protein 1-like 1 2.29035
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.28902
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.28355
TCF15 transcription factor 15 (basic helix-loop-helix) 2.27995
TBK1 TANK-binding kinase 1 2.27835
NT5C 5', 3'-nucleotidase, cytosolic 2.2742
NUAK2 NUAK family, SNF1-like kinase, 2 2.27295
KMT5A lysine methyltransferase 5A 2.26605
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.26405
LSG1 large 60S subunit nuclear export GTPase 1 2.26347
EML3 echinoderm microtubule associated protein like 3 2.26323
ZNF227 zinc finger protein 227 2.26175
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 2.26027
LIF leukemia inhibitory factor 2.25955
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 2.2541
HDAC7 histone deacetylase 7 2.2525
TSPYL2 TSPY-like 2 2.2511
RBKS ribokinase 2.24848
DDB1 damage-specific DNA binding protein 1, 127kDa 2.24525
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 2.24443
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.2438
TEX10 testis expressed 10 2.23965
CDIP1 cell death-inducing p53 target 1 2.23485
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 2.23325
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 2.2277
CDR2L cerebellar degeneration-related protein 2-like 2.22325
RAB1B RAB1B, member RAS oncogene family 2.21935
DZANK1 double zinc ribbon and ankyrin repeat domains 1 2.2193
SLC75A1 solute carrier family 75 member 1 2.2169
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.2155
TPST1 tyrosylprotein sulfotransferase 1 2.21255
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 2.21105
CYB561 cytochrome b561 2.20906
THUMPD2 THUMP domain containing 2 2.20835
MBD1 methyl-CpG binding domain protein 1 2.20705
RAB9A RAB9A, member RAS oncogene family 2.20695
UIMC1 ubiquitin interaction motif containing 1 2.2063
TEAD3 TEA domain family member 3 2.20465
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 2.2046
UBL4A ubiquitin-like 4A 2.20365
PORCN porcupine homolog (Drosophila) 2.20155
TFE3 transcription factor binding to IGHM enhancer 3 2.1982
AP2M1 adaptor-related protein complex 2, mu 1 subunit 2.19395
SAR1B secretion associated, Ras related GTPase 1B 2.19275
MICA MHC class I polypeptide-related sequence A 2.18972
LRRC42 leucine rich repeat containing 42 2.18745
CRK v-crk avian sarcoma virus CT10 oncogene homolog 2.18438
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 2.17575
MAP3K14 mitogen-activated protein kinase kinase kinase 14 2.174
RNF25 ring finger protein 25 2.1719
ZYX zyxin 2.17097
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) 2.166
GYS1 glycogen synthase 1 (muscle) 2.15415
DGKA diacylglycerol kinase, alpha 80kDa 2.15053
GSDME gasdermin E 2.149
GMPR guanosine monophosphate reductase 2.14855
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 2.14455
EDN2 endothelin 2 2.14315
PHF1 PHD finger protein 1 2.141
UBE2H ubiquitin-conjugating enzyme E2H 2.1394
MBOAT7 membrane bound O-acyltransferase domain containing 7 2.13625
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 2.13545
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit 2.13335
SLC25A44 solute carrier family 25, member 44 2.12917
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 2.12905
PROCR protein C receptor, endothelial 2.1276
ZDHHC24 zinc finger, DHHC-type containing 24 2.1261
YY1AP1 YY1 associated protein 1 2.1235
PIR pirin (iron-binding nuclear protein) 2.12315
LAP3 leucine aminopeptidase 3 2.1208
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.12065
VLDLR very low density lipoprotein receptor 2.1195
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 2.11763
GANAB glucosidase, alpha; neutral AB 2.11127
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 2.1096
SDF2 stromal cell-derived factor 2 2.1081
OPLAH 5-oxoprolinase (ATP-hydrolysing) 2.1079
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 2.1071
CIC capicua transcriptional repressor 2.1047
RRAGC Ras-related GTP binding C 2.10435
ANAPC2 anaphase promoting complex subunit 2 2.10435
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 2.1002
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit 2.0989
PXDC1 PX domain containing 1 2.0938
G0S2 G0/G1 switch 2 2.09085
EAPP E2F-associated phosphoprotein 2.0886
METTL22 methyltransferase like 22 2.0865
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa 2.08555
MED9 mediator complex subunit 9 2.0848
PRCP prolylcarboxypeptidase (angiotensinase C) 2.08325
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.08238
STIP1 stress-induced phosphoprotein 1 2.08183
TOM1L1 target of myb1 (chicken)-like 1 2.0817
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 2.0814
KRT8 keratin 8, type II 2.0813
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2 2.08125
ADAM15 ADAM metallopeptidase domain 15 2.07995
SCAND1 SCAN domain containing 1 2.07955
TBC1D31 TBC1 domain family, member 31 2.0769
RIC8A RIC8 guanine nucleotide exchange factor A 2.07655
HPSE heparanase 2.0747
PLTP phospholipid transfer protein 2.07215
ZXDC ZXD family zinc finger C 2.06795
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 2.0659
OFD1 oral-facial-digital syndrome 1 2.06505
PARP2 poly (ADP-ribose) polymerase 2 2.06122
ZNF580 zinc finger protein 580 2.0605
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 2.05965
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 2.05795
GOLM1 golgi membrane protein 1 2.055
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 2.05387
CLK3 CDC-like kinase 3 2.053
RPRD2 regulation of nuclear pre-mRNA domain containing 2 2.05045
GNL1 guanine nucleotide binding protein-like 1 2.04855
NFRKB nuclear factor related to kappaB binding protein 2.04565
HROB homologous recombination factor with OB-fold 2.03745
CDK11A cyclin-dependent kinase 11A 2.03503
LTB4R leukotriene B4 receptor 2.03415
PILRB paired immunoglobin-like type 2 receptor beta 2.0264
PLEC plectin 2.0204
ALX1 ALX homeobox 1 2.02
CORO1A coronin, actin binding protein, 1A 2.0166
BBC3 BCL2 binding component 3 2.01435
SH3GL1 SH3-domain GRB2-like 1 2.01255
COL16A1 collagen, type XVI, alpha 1 2.0116
NQO1 NAD(P)H dehydrogenase, quinone 1 2.00573
CNPPD1 cyclin Pas1/PHO80 domain containing 1 2.00507
METTL25B methyltransferase like 25B 2.00495
CHAMP1 chromosome alignment maintaining phosphoprotein 1 2.00415
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 2.00385
TSPAN3 tetraspanin 3 2.00202

decreased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 -10.0
FGFR4 fibroblast growth factor receptor 4 -8.20005
PECR peroxisomal trans-2-enoyl-CoA reductase -7.88905
PGM1 phosphoglucomutase 1 -7.64645
PYCR1 pyrroline-5-carboxylate reductase 1 -7.6316
C5 complement component 5 -7.39305
MSRA methionine sulfoxide reductase A -7.2254
CDC20 cell division cycle 20 -7.19475
HMGA2 high mobility group AT-hook 2 -7.10705
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -7.08625
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -6.81735
TCTN1 tectonic family member 1 -6.6093
RPIA ribose 5-phosphate isomerase A -6.5898
PCCB propionyl CoA carboxylase, beta polypeptide -6.552
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -6.5215
USP6NL USP6 N-terminal like -6.4314
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -6.32265
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -6.27598
RSU1 Ras suppressor protein 1 -6.2434
PLK1 polo-like kinase 1 -6.0567
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -6.05435
ZW10 zw10 kinetochore protein -5.9537
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -5.91222
ANO10 anoctamin 10 -5.8987
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -5.8942
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -5.88507
PSRC1 proline/serine-rich coiled-coil 1 -5.78055
CCNA2 cyclin A2 -5.69222
AURKB aurora kinase B -5.60645
ISOC1 isochorismatase domain containing 1 -5.48225
CCNB1 cyclin B1 -5.44345
STMN1 stathmin 1 -5.4039
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -5.26175
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -5.21655
HEATR1 HEAT repeat containing 1 -5.17922
MRPS16 mitochondrial ribosomal protein S16 -5.14995
C2CD5 C2 calcium-dependent domain containing 5 -5.0959
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -5.0513
MNAT1 MNAT CDK-activating kinase assembly factor 1 -4.9726
PROS1 protein S (alpha) -4.95215
SYNE2 spectrin repeat containing, nuclear envelope 2 -4.9228
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -4.9105
CLIC4 chloride intracellular channel 4 -4.8305
SOAT2 sterol O-acyltransferase 2 -4.69457
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -4.6638
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -4.6599
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -4.5666
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -4.5284
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -4.4384
CDK1 cyclin-dependent kinase 1 -4.36727
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -4.2849
ENOPH1 enolase-phosphatase 1 -4.2783
PCNA proliferating cell nuclear antigen -4.2674
MRPL12 mitochondrial ribosomal protein L12 -4.26705
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -4.26585
APOH apolipoprotein H (beta-2-glycoprotein I) -4.1917
CHMP6 charged multivesicular body protein 6 -4.1869
AHSG alpha-2-HS-glycoprotein -4.1769
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -4.13983
NUP133 nucleoporin 133kDa -4.12715
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -3.9852
ASGR1 asialoglycoprotein receptor 1 -3.9794
CDK4 cyclin-dependent kinase 4 -3.97545
AMBP alpha-1-microglobulin/bikunin precursor -3.96335
HLA-DMA major histocompatibility complex, class II, DM alpha -3.9613
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -3.95935
NIPSNAP1 nipsnap homolog 1 (C. elegans) -3.95695
MIS18A MIS18 kinetochore protein A -3.94675
GET1 guided entry of tail-anchored proteins factor 1 -3.93035
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 -3.90725
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 -3.9035
FOS FBJ murine osteosarcoma viral oncogene homolog -3.87875
KIF15 kinesin family member 15 -3.87185
MTA1 metastasis associated 1 -3.81017
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -3.81005
SPAG4 sperm associated antigen 4 -3.7819
MYLK myosin light chain kinase -3.75275
A1CF APOBEC1 complementation factor -3.7475
SLC35F2 solute carrier family 35, member F2 -3.74565
TRIB3 tribbles pseudokinase 3 -3.74225
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -3.72945
WDR7 WD repeat domain 7 -3.6519
CPB2 carboxypeptidase B2 (plasma) -3.64995
TBC1D8B TBC1 domain family, member 8B (with GRAM domain) -3.64145
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -3.64067
UBE2C ubiquitin-conjugating enzyme E2C -3.6388
COPB2 coatomer protein complex, subunit beta 2 (beta prime) -3.6357
NT5DC2 5'-nucleotidase domain containing 2 -3.6343
NCK2 NCK adaptor protein 2 -3.63135
APOA2 apolipoprotein A-II -3.59982
FBF1 Fas (TNFRSF6) binding factor 1 -3.59487
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -3.51805
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 -3.49501
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -3.4945
SAA4 serum amyloid A4, constitutive -3.4839
CDO1 cysteine dioxygenase type 1 -3.47865
AKR1D1 aldo-keto reductase family 1, member D1 -3.47225
LBR lamin B receptor -3.4722
TLCD3A TLC domain containing 3A -3.4715
PLXDC2 plexin domain containing 2 -3.44715
BIRC5 baculoviral IAP repeat containing 5 -3.41483
HADH hydroxyacyl-CoA dehydrogenase -3.40687
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -3.3934
CTSL cathepsin L -3.3758
PNPLA3 patatin-like phospholipase domain containing 3 -3.3739
DSCC1 DNA replication and sister chromatid cohesion 1 -3.37345
COL1A2 collagen, type I, alpha 2 -3.36057
LOC124907782 dual specificity protein phosphatase 22 -3.34195
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -3.34085
SLC44A1 solute carrier family 44 (choline transporter), member 1 -3.33525
CFHR2 complement factor H-related 2 -3.32475
ACAA1 acetyl-CoA acyltransferase 1 -3.31337
ITGB5 integrin, beta 5 -3.3097
APOC3 apolipoprotein C-III -3.30285
MYC v-myc avian myelocytomatosis viral oncogene homolog -3.3001
LGALS8 lectin, galactoside-binding, soluble, 8 -3.27715
ASGR2 asialoglycoprotein receptor 2 -3.2699
ERBB2 erb-b2 receptor tyrosine kinase 2 -3.23028
MYRIP myosin VIIA and Rab interacting protein -3.22115
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -3.21885
SNX6 sorting nexin 6 -3.21865
USP1 ubiquitin specific peptidase 1 -3.20395
ADH6 alcohol dehydrogenase 6 (class V) -3.18342
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -3.18323
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -3.18255
APOM apolipoprotein M -3.1645
GFOD1 glucose-fructose oxidoreductase domain containing 1 -3.16195
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -3.15795
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -3.15545
FABP1 fatty acid binding protein 1, liver -3.1388
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -3.1311
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -3.1233
MYO10 myosin X -3.12153
L1TD1 LINE-1 type transposase domain containing 1 -3.11985
TRAK2 trafficking protein, kinesin binding 2 -3.10317
SLC17A2 solute carrier family 17, member 2 -3.09235
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -3.0883
PHKB phosphorylase kinase, beta -3.08787
NRIP1 nuclear receptor interacting protein 1 -3.08613
PAH phenylalanine hydroxylase -3.08363
UGDH UDP-glucose 6-dehydrogenase -3.082
HAT1 histone acetyltransferase 1 -3.0628
GPC3 glypican 3 -3.052
EDIL3 EGF-like repeats and discoidin I-like domains 3 -3.04775
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2 -3.0419
ANAPC15 anaphase promoting complex subunit 15 -3.04085
GIPC2 GIPC PDZ domain containing family, member 2 -3.03995
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -3.0195
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 -3.01295
MRPS30 mitochondrial ribosomal protein S30 -3.01183
TMEM97 transmembrane protein 97 -3.0114
EMID1 EMI domain containing 1 -3.0112
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 -3.00945
ITFG1 integrin alpha FG-GAP repeat containing 1 -3.0052
MYOC myocilin, trabecular meshwork inducible glucocorticoid response -2.9979
SYNJ2BP synaptojanin 2 binding protein -2.9891
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -2.9805
HNMT histamine N-methyltransferase -2.96628
FBXO5 F-box protein 5 -2.96535
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -2.9623
RFC2 replication factor C (activator 1) 2, 40kDa -2.95495
OXA1L oxidase (cytochrome c) assembly 1-like -2.9521
BZW2 basic leucine zipper and W2 domains 2 -2.95005
AP1AR adaptor-related protein complex 1 associated regulatory protein -2.9369
SLC30A10 solute carrier family 30, member 10 -2.9358
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -2.93215
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 -2.92275
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) -2.9168
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.916
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 -2.89385
CENPM centromere protein M -2.88635
ABI3BP ABI family, member 3 (NESH) binding protein -2.87985
ANXA7 annexin A7 -2.87278
LARS1 leucyl-tRNA synthetase 1 -2.872
FGA fibrinogen alpha chain -2.87135
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 -2.85733
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -2.85478
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -2.8509
SLC66A2 solute carrier family 66 member 2 -2.839
TBC1D12 TBC1 domain family, member 12 -2.83475
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -2.83345
CRIPTO3 cripto, EGF-CFC family member 3 -2.8295
SIPA1L1 signal-induced proliferation-associated 1 like 1 -2.8274
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -2.82355
ANG angiogenin, ribonuclease, RNase A family, 5 -2.8193
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.8156
PHGDH phosphoglycerate dehydrogenase -2.80515
PEG3 paternally expressed 3 -2.8
HMGB2 high mobility group box 2 -2.79945
AGXT alanine-glyoxylate aminotransferase -2.79708
TF transferrin -2.79386
CHEK2 checkpoint kinase 2 -2.78963
SOX5 SRY (sex determining region Y)-box 5 -2.7664
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.76175
CASP3 caspase 3, apoptosis-related cysteine peptidase -2.75405
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9 -2.75145
GAP43 growth associated protein 43 -2.74907
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) -2.7398
GPR88 G protein-coupled receptor 88 -2.73935
RTRAF RNA transcription, translation and transport factor -2.7386
DENR density-regulated protein -2.73795
ALDOC aldolase C, fructose-bisphosphate -2.7377
RABAC1 Rab acceptor 1 (prenylated) -2.73715
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -2.73555
TPM1 tropomyosin 1 (alpha) -2.73064
USP46 ubiquitin specific peptidase 46 -2.71738
AMT aminomethyltransferase -2.71
MAT1A methionine adenosyltransferase I, alpha -2.70935
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -2.70854
ONECUT2 one cut homeobox 2 -2.7046
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.70435
CAPN9 calpain 9 -2.70417
LEFTY1 left-right determination factor 1 -2.7024
CHRM3 cholinergic receptor, muscarinic 3 -2.6987
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -2.69705
DERA deoxyribose-phosphate aldolase (putative) -2.6956
F13B coagulation factor XIII, B polypeptide -2.6928
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -2.6904
SELENOF selenoprotein F -2.674
DPYSL2 dihydropyrimidinase-like 2 -2.66665
HPX hemopexin -2.66655
GATA4 GATA binding protein 4 -2.66625
RHOBTB1 Rho-related BTB domain containing 1 -2.6641
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -2.66107
TBC1D4 TBC1 domain family, member 4 -2.6606
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.6535
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 -2.65295
LRRC59 leucine rich repeat containing 59 -2.6501
RAB15 RAB15, member RAS oncogene family -2.6492
VSNL1 visinin-like 1 -2.64648
USP39 ubiquitin specific peptidase 39 -2.64635
KLF6 Kruppel-like factor 6 -2.64353
WDR18 WD repeat domain 18 -2.64255
NTSR1 neurotensin receptor 1 (high affinity) -2.64195
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.63495
MCMBP minichromosome maintenance complex binding protein -2.63445
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -2.6308
VRK1 vaccinia related kinase 1 -2.6146
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.61322
VGLL4 vestigial-like family member 4 -2.6128
CADPS2 Ca++-dependent secretion activator 2 -2.61
PLG plasminogen -2.60628
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.6057
KERA keratocan -2.6048
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 -2.60285
COL6A3 collagen, type VI, alpha 3 -2.6012
PIPOX pipecolic acid oxidase -2.5979
DENND10 DENN domain containing 10 -2.5923
VCAM1 vascular cell adhesion molecule 1 -2.5805
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) -2.58035
VTN vitronectin -2.5734
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -2.5727
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.57095
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 -2.57045
TTC3 tetratricopeptide repeat domain 3 -2.5702
PLPBP pyridoxal phosphate binding protein -2.56842
ZIM2 zinc finger, imprinted 2 -2.56225
MYO1D myosin ID -2.5588
WASHC5 WASH complex subunit 5 -2.5496
PDK3 pyruvate dehydrogenase kinase, isozyme 3 -2.54443
PANK3 pantothenate kinase 3 -2.5401
ATF6 activating transcription factor 6 -2.53883
USP12 ubiquitin specific peptidase 12 -2.537
MPHOSPH6 M-phase phosphoprotein 6 -2.5298
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 -2.5273
MBNL3 muscleblind-like splicing regulator 3 -2.52725
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -2.52633
F9 coagulation factor IX -2.52365
CPVL carboxypeptidase, vitellogenic-like -2.52355
PEX5L peroxisomal biogenesis factor 5-like -2.52
CER1 cerberus 1, DAN family BMP antagonist -2.5196
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 -2.51685
TEDC2 tubulin epsilon and delta complex 2 -2.51455
SATB2 SATB homeobox 2 -2.51455
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 -2.51033
RNASE4 ribonuclease, RNase A family, 4 -2.50903
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -2.5069
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 -2.49955
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 -2.49275
MSH6 mutS homolog 6 -2.49217
AK4 adenylate kinase 4 -2.48885
TRAPPC6A trafficking protein particle complex 6A -2.48805
MBL2 mannose-binding lectin (protein C) 2, soluble -2.4869
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.4838
IGFBP1 insulin-like growth factor binding protein 1 -2.482
NLGN4Y neuroligin 4, Y-linked -2.4806
CFHR5 complement factor H-related 5 -2.47915
ATP10A ATPase, class V, type 10A -2.4765
GMDS GDP-mannose 4,6-dehydratase -2.47035
CMKLR1 chemerin chemokine-like receptor 1 -2.4703
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -2.4701
RGN regucalcin -2.4697
ANKH ANKH inorganic pyrophosphate transport regulator -2.4689
ATRNL1 attractin-like 1 -2.46837
ZBTB14 zinc finger and BTB domain containing 14 -2.46765
LRRC31 leucine rich repeat containing 31 -2.4674
NUP85 nucleoporin 85kDa -2.4664
SLC38A4 solute carrier family 38, member 4 -2.46565
RUNDC3B RUN domain containing 3B -2.4592
PTGER4 prostaglandin E receptor 4 (subtype EP4) -2.45592
GLDC glycine dehydrogenase (decarboxylating) -2.4534
FMOD fibromodulin -2.45
ZMIZ1 zinc finger, MIZ-type containing 1 -2.4465
NTAQ1 N-terminal glutamine amidase 1 -2.4461
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.4433
PCCA propionyl CoA carboxylase, alpha polypeptide -2.4432
ZNF385D zinc finger protein 385D -2.4403
TM4SF5 transmembrane 4 L six family member 5 -2.4378
QPRT quinolinate phosphoribosyltransferase -2.43735
ANAPC1 anaphase promoting complex subunit 1 -2.43465
COL3A1 collagen, type III, alpha 1 -2.42962
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.4293
USO1 USO1 vesicle transport factor -2.42645
MCUB mitochondrial calcium uniporter dominant negative subunit beta -2.4227
ORM2 orosomucoid 2 -2.42165
EPHA4 EPH receptor A4 -2.421
TAGLN3 transgelin 3 -2.41955
EIF2D eukaryotic translation initiation factor 2D -2.41945
MTUS2 microtubule associated tumor suppressor candidate 2 -2.41875
ELAVL2 ELAV like neuron-specific RNA binding protein 2 -2.4178
HNRNPCL1 heterogeneous nuclear ribonucleoprotein C-like 1 -2.41735
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -2.41625
SLN sarcolipin -2.41395
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 -2.4118
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -2.40913
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide -2.4085
INHBE inhibin, beta E -2.40825
LIPC lipase, hepatic -2.4081
LIME1 Lck interacting transmembrane adaptor 1 -2.40785
TMPRSS5 transmembrane protease, serine 5 -2.40685
BLMH bleomycin hydrolase -2.406
CCT8 chaperonin containing TCP1, subunit 8 (theta) -2.39795
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 -2.39783
CAB39 calcium binding protein 39 -2.3961
PDE5A phosphodiesterase 5A, cGMP-specific -2.39485
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 -2.39342
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D -2.39325
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -2.3915
DDR2 discoidin domain receptor tyrosine kinase 2 -2.38535
BRD7 bromodomain containing 7 -2.384
CA9 carbonic anhydrase IX -2.38365
BMP4 bone morphogenetic protein 4 -2.3834
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 -2.38225
PTPRD protein tyrosine phosphatase, receptor type, D -2.38148
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -2.37995
NPC2 Niemann-Pick disease, type C2 -2.3769
KALRN kalirin, RhoGEF kinase -2.3767
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.37635
TACC1 transforming, acidic coiled-coil containing protein 1 -2.36672
ACTA1 actin, alpha 1, skeletal muscle -2.3656
FZD7 frizzled class receptor 7 -2.3633
KLHDC2 kelch domain containing 2 -2.3563
NFIL3 nuclear factor, interleukin 3 regulated -2.35175
TOP2B topoisomerase (DNA) II beta 180kDa -2.34975
NRTN neurturin -2.3473
SYNPO2L synaptopodin 2-like -2.34655
SCN1A sodium channel, voltage gated, type I alpha subunit -2.3448
PXMP2 peroxisomal membrane protein 2, 22kDa -2.33825
SCCPDH saccharopine dehydrogenase (putative) -2.33742
NOX1 NADPH oxidase 1 -2.33536
PTPRB protein tyrosine phosphatase, receptor type, B -2.3327
ENTREP2 endosomal transmembrane epsin interactor 2 -2.3325
SYTL3 synaptotagmin-like 3 -2.3311
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 -2.33005
DCHS2 dachsous cadherin-related 2 -2.3289
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 -2.3284
NUP93 nucleoporin 93kDa -2.32625
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.3226
SQLE squalene epoxidase -2.32092
USP9Y ubiquitin specific peptidase 9, Y-linked -2.3199
SLF2 SMC5-SMC6 complex localization factor 2 -2.3189
SLC68A1 solute carrier family 68 member 1 -2.3072
PLSCR4 phospholipid scramblase 4 -2.3065
TCERG1 transcription elongation regulator 1 -2.3064
PIGR polymeric immunoglobulin receptor -2.30635
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -2.3057
PID1 phosphotyrosine interaction domain containing 1 -2.29735
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.2926
NR3C2 nuclear receptor subfamily 3, group C, member 2 -2.29055
ZNF514 zinc finger protein 514 -2.28625
RBM34 RNA binding motif protein 34 -2.285
GOLGA4 golgin A4 -2.28375
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.28255
PCDHGA3 protocadherin gamma subfamily A, 3 -2.2822
TLR5 toll-like receptor 5 -2.27715
TUBG1 tubulin, gamma 1 -2.2754
FTCD formimidoyltransferase cyclodeaminase -2.2743
CLIC3 chloride intracellular channel 3 -2.27305
MPZL2 myelin protein zero-like 2 -2.26835
MRPS7 mitochondrial ribosomal protein S7 -2.2665
PEBP1 phosphatidylethanolamine binding protein 1 -2.2656
KDM5D lysine (K)-specific demethylase 5D -2.26065
ZIC1 Zic family member 1 -2.2558
TOMM70 translocase of outer mitochondrial membrane 70 -2.25423
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -2.253
LATS1 large tumor suppressor kinase 1 -2.25175
RPL36AL ribosomal protein L36a-like -2.2484
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 -2.24503
TFRC transferrin receptor -2.24382
C8B complement component 8, beta polypeptide -2.24285
UXT ubiquitously-expressed, prefoldin-like chaperone -2.23781
DKK2 dickkopf WNT signaling pathway inhibitor 2 -2.23735
VSIG4 V-set and immunoglobulin domain containing 4 -2.2351
CFHR3 complement factor H-related 3 -2.2331
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C -2.23265
RRAGA Ras-related GTP binding A -2.2245
SCD stearoyl-CoA desaturase (delta-9-desaturase) -2.22399
EDN1 endothelin 1 -2.22265
TM9SF2 transmembrane 9 superfamily member 2 -2.22075
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -2.22035
CDKN3 cyclin-dependent kinase inhibitor 3 -2.21625
TRIM24 tripartite motif containing 24 -2.21397
FABP7 fatty acid binding protein 7, brain -2.21332
TTR transthyretin -2.20635
LRRC2 leucine rich repeat containing 2 -2.20575
APOA1 apolipoprotein A-I -2.20525
CHL1 cell adhesion molecule L1-like -2.20465
PGAM4 phosphoglycerate mutase family member 4 -2.20325
SYP synaptophysin -2.2019
AGGF1 angiogenic factor with G patch and FHA domains 1 -2.20143
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 -2.20135
TTF2 transcription termination factor, RNA polymerase II -2.20045
NDP Norrie disease (pseudoglioma) -2.1992
LDHA lactate dehydrogenase A -2.19625
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -2.19515
CYBA cytochrome b-245, alpha polypeptide -2.1923
POU4F2 POU class 4 homeobox 2 -2.1899
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 -2.18865
SYN2 synapsin II -2.18765
HELLS helicase, lymphoid-specific -2.18665
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -2.1855
CPNE2 copine II -2.185
ADNP2 ADNP homeobox 2 -2.18305
GAST gastrin -2.1824
GPHN gephyrin -2.1798
FCGRT Fc fragment of IgG, receptor, transporter, alpha -2.1798
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -2.1771
MATN1 matrilin 1, cartilage matrix protein -2.1732
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme -2.17
SNRPA small nuclear ribonucleoprotein polypeptide A -2.1691
TUBB4A tubulin, beta 4A class IVa -2.1691
CASQ2 calsequestrin 2 (cardiac muscle) -2.16725
FAM20B family with sequence similarity 20, member B -2.16563
TIPRL TOR signaling pathway regulator -2.1649
FGL2 fibrinogen-like 2 -2.16355
AARS1 alanyl-tRNA synthetase 1 -2.1631
DUT deoxyuridine triphosphatase -2.16278
ADAMTSL4 ADAMTS-like 4 -2.16155
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase -2.16147
RASA3 RAS p21 protein activator 3 -2.16103
NNT nicotinamide nucleotide transhydrogenase -2.161
NLGN4X neuroligin 4, X-linked -2.1594
COBL cordon-bleu WH2 repeat protein -2.159
MAP7 microtubule-associated protein 7 -2.15808
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -2.15715
ARF1 ADP-ribosylation factor 1 -2.1533
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -2.15145
SUSD5 sushi domain containing 5 -2.1474
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -2.14587
PHACTR2 phosphatase and actin regulator 2 -2.14492
GPR12 G protein-coupled receptor 12 -2.1432
MCRS1 microspherule protein 1 -2.14295
CCDC177 coiled-coil domain containing 177 -2.14285
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.14275
RGS2 regulator of G-protein signaling 2 -2.1425
KHK ketohexokinase (fructokinase) -2.14148
CDK14 cyclin-dependent kinase 14 -2.14138
VIPR1 vasoactive intestinal peptide receptor 1 -2.13905
GNA12 guanine nucleotide binding protein (G protein) alpha 12 -2.1386
MYL1 myosin, light chain 1, alkali; skeletal, fast -2.1381
ATOH1 atonal homolog 1 (Drosophila) -2.1373
FHL5 four and a half LIM domains 5 -2.13505
TFB1M transcription factor B1, mitochondrial -2.1332
CA3 carbonic anhydrase III -2.1311
CYP3A7-CYP3A51P CYP3A7-CYP3A51P readthrough -2.1298
GFUS GDP-L-fucose synthase -2.12572
MSMO1 methylsterol monooxygenase 1 -2.125
EBAG9 estrogen receptor binding site associated, antigen, 9 -2.1226
FGB fibrinogen beta chain -2.12232
CDCA4 cell division cycle associated 4 -2.122
CEP192 centrosomal protein 192kDa -2.1194
DCK deoxycytidine kinase -2.119
SAE1 SUMO1 activating enzyme subunit 1 -2.11725
RBP4 retinol binding protein 4, plasma -2.11665
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.1143
GPX4 glutathione peroxidase 4 -2.11415
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 -2.112
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog -2.11189
CETN3 centrin, EF-hand protein, 3 -2.1118
MAPK10 mitogen-activated protein kinase 10 -2.1108
PSME3IP1 proteasome activator subunit 3 interacting protein 1 -2.1106
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -2.10885
SEPTIN11 septin 11 -2.10693
PRMT2 protein arginine methyltransferase 2 -2.10535
ACSM2A acyl-CoA synthetase medium-chain family member 2A -2.10365
EVI5 ecotropic viral integration site 5 -2.1033
FGL1 fibrinogen-like 1 -2.10205
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 -2.10095
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) -2.10055
GLRX5 glutaredoxin 5 -2.0973
IL17RB interleukin 17 receptor B -2.0951
TAS2R4 taste receptor, type 2, member 4 -2.0949
GJB1 gap junction protein, beta 1, 32kDa -2.09
ELOVL2 ELOVL fatty acid elongase 2 -2.08608
EFHD1 EF-hand domain family, member D1 -2.08415
ANKRD28 ankyrin repeat domain 28 -2.08205
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 -2.08085
SCAMP5 secretory carrier membrane protein 5 -2.079
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) -2.0756
GPC5 glypican 5 -2.07555
PROX1 prospero homeobox 1 -2.07305
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -2.07115
CDX1 caudal type homeobox 1 -2.0708
PPP1R7 protein phosphatase 1, regulatory subunit 7 -2.07003
KIAA0586 KIAA0586 -2.0697
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.06905
MYL4 myosin, light chain 4, alkali; atrial, embryonic -2.06677
DHCR24 24-dehydrocholesterol reductase -2.06525
RAB4B RAB4B, member RAS oncogene family -2.06445
CSPG4 chondroitin sulfate proteoglycan 4 -2.06258
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -2.06255
TPSG1 tryptase gamma 1 -2.0616
ARB2A ARB2 cotranscriptional regulator A -2.0615
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.05557
AURKA aurora kinase A -2.05525
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10 -2.0548
NXPE4 neurexophilin and PC-esterase domain family, member 4 -2.05465
CYRIA CYFIP related Rac1 interactor A -2.0531
PAPOLA poly(A) polymerase alpha -2.05117
TTC9 tetratricopeptide repeat domain 9 -2.04962
PRLR prolactin receptor -2.04866
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) -2.04757
PIEZO2 piezo-type mechanosensitive ion channel component 2 -2.04695
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -2.04695
RTN3 reticulon 3 -2.0463
INSIG1 insulin induced gene 1 -2.04492
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta -2.0412
HBG1 hemoglobin, gamma A -2.04088
TTC27 tetratricopeptide repeat domain 27 -2.0399
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13 -2.03795
SGPP2 sphingosine-1-phosphate phosphatase 2 -2.03775
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 -2.03669
CLCN5 chloride channel, voltage-sensitive 5 -2.03445
PCDHGA10 protocadherin gamma subfamily A, 10 -2.0329
MILR1 mast cell immunoglobulin-like receptor 1 -2.03125
MYH7B myosin, heavy chain 7B, cardiac muscle, beta -2.03085
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -2.0305
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin -2.0283
SPHK2 sphingosine kinase 2 -2.02387
PHYH phytanoyl-CoA 2-hydroxylase -2.0228
PLCE1 phospholipase C, epsilon 1 -2.02067
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 -2.02047
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4 -2.01922
EDAR ectodysplasin A receptor -2.0192
KRTAP5-2 keratin associated protein 5-2 -2.0191
APOF apolipoprotein F -2.01665
TFAM transcription factor A, mitochondrial -2.01592
PHOSPHO2-KLHL23 PHOSPHO2-KLHL23 readthrough -2.0133
STAMBP STAM binding protein -2.01285
GPT glutamic-pyruvate transaminase (alanine aminotransferase) -2.011
PRODH2 proline dehydrogenase (oxidase) 2 -2.01075
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 -2.00908
PF4V1 platelet factor 4 variant 1 -2.00585
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -2.00435
KATNBL1 katanin p80 subunit B-like 1 -2.00345
NPAS2 neuronal PAS domain protein 2 -2.00323
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.00145
PI15 peptidase inhibitor 15 -2.0003