| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | succinic anhydride 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
56 genes differentially expressed following the CRCGN008_HEPG2_24H:L24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 10.0 |
| STK10 | serine/threonine kinase 10 | 6.59772 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 5.64285 |
| MOK | MOK protein kinase | 4.8612 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.30315 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 4.07795 |
| MAMLD1 | mastermind-like domain containing 1 | 3.6996 |
| EGF | epidermal growth factor | 3.62955 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 3.6212 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.3709 |
| HSPA1A | heat shock 70kDa protein 1A | 3.05655 |
| CHN1 | chimerin 1 | 3.04765 |
| CDCA4 | cell division cycle associated 4 | 3.03865 |
| BAD | BCL2-associated agonist of cell death | 2.7917 |
| KIF20A | kinesin family member 20A | 2.6854 |
| GATA4 | GATA binding protein 4 | 2.4098 |
| PARL | presenilin associated, rhomboid-like | 2.3457 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | 2.30015 |
| EVL | Enah/Vasp-like | 2.29325 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.2848 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 2.2696 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.25877 |
| SLC25A16 | solute carrier family 25 (mitochondrial carrier), member 16 | 2.20295 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 2.18055 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 2.0957 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 2.0887 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TUBB6 | tubulin, beta 6 class V | -4.9824 |
| LDHD | lactate dehydrogenase D | -4.77875 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.75485 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.7001 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.6992 |
| ADI1 | acireductone dioxygenase 1 | -4.61865 |
| MAPK13 | mitogen-activated protein kinase 13 | -4.45703 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.4549 |
| CCNB2 | cyclin B2 | -3.3887 |
| RGS2 | regulator of G-protein signaling 2 | -3.31735 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -3.2326 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -3.14867 |
| WASHC4 | WASH complex subunit 4 | -3.02333 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.97625 |
| RAI14 | retinoic acid induced 14 | -2.82445 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -2.6415 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -2.48125 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.42667 |
| CRIP2 | cysteine-rich protein 2 | -2.422 |
| TXNDC9 | thioredoxin domain containing 9 | -2.33822 |
| EPHA1 | EPH receptor A1 | -2.22965 |
| RBM6 | RNA binding motif protein 6 | -2.20235 |
| PRPF4 | pre-mRNA processing factor 4 | -2.17742 |
| AKAP11 | A kinase (PRKA) anchor protein 11 | -2.13385 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.113 |
| EVPL | envoplakin | -2.0972 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -2.0868 |
| NECTIN2 | nectin cell adhesion molecule 2 | -2.08215 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.0736 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.0162 |
