| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2,4-diaminotoluene 19.6 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
78 genes differentially expressed following the CRCGN008_HEPG2_24H:M02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LOC122526780 | uncharacterized LOC122526780 | 6.6766 |
| KLHL21 | kelch-like family member 21 | 5.48885 |
| NOTCH1 | notch 1 | 5.1365 |
| STK10 | serine/threonine kinase 10 | 5.06647 |
| AMDHD2 | amidohydrolase domain containing 2 | 5.0305 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.99485 |
| LSR | lipolysis stimulated lipoprotein receptor | 4.78805 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 4.7048 |
| UBQLN2 | ubiquilin 2 | 4.6113 |
| ARL4C | ADP-ribosylation factor-like 4C | 4.42887 |
| CCNA1 | cyclin A1 | 4.25045 |
| ABHD6 | abhydrolase domain containing 6 | 4.14808 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 4.0516 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 3.87305 |
| CYCS | cytochrome c, somatic | 3.49355 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 3.40433 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.33155 |
| NMU | neuromedin U | 3.29455 |
| METRN | meteorin, glial cell differentiation regulator | 3.1816 |
| CHN1 | chimerin 1 | 3.1577 |
| KIF20A | kinesin family member 20A | 2.8467 |
| GPATCH8 | G patch domain containing 8 | 2.78793 |
| PARP2 | poly (ADP-ribose) polymerase 2 | 2.74817 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.71673 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.70923 |
| SIRT3 | sirtuin 3 | 2.64502 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.6237 |
| VAT1 | vesicle amine transport 1 | 2.5501 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.39915 |
| ALG9 | ALG9, alpha-1,2-mannosyltransferase | 2.2986 |
| ZBTB7C | zinc finger and BTB domain containing 7C | 2.2913 |
| APBA3 | amyloid beta (A4) precursor protein-binding, family A, member 3 | 2.2494 |
| SAP30L | SAP30-like | 2.23245 |
| HMOX1 | heme oxygenase 1 | 2.2159 |
| ACAD8 | acyl-CoA dehydrogenase family, member 8 | 2.15945 |
| NDC1 | NDC1 transmembrane nucleoporin | 2.1585 |
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) | 2.1113 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.0996 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.08535 |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 | 2.0334 |
| ADGRB2 | adhesion G protein-coupled receptor B2 | 2.0158 |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein | 2.01295 |
| HOXA1 | homeobox A1 | 2.0123 |
| TYK2 | tyrosine kinase 2 | 2.0023 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -9.32075 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | -6.1706 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -6.08655 |
| ZNF586 | zinc finger protein 586 | -5.674 |
| C5 | complement component 5 | -5.524 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -5.21635 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -5.0 |
| SCAND1 | SCAN domain containing 1 | -4.86345 |
| PCNA | proliferating cell nuclear antigen | -4.81965 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -4.5619 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -4.51955 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.46635 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -4.3809 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -4.0258 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.95535 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.7191 |
| RNF167 | ring finger protein 167 | -3.556 |
| ZNF134 | zinc finger protein 134 | -2.6317 |
| SPAG4 | sperm associated antigen 4 | -2.6084 |
| MYNN | myoneurin | -2.57865 |
| DDX43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 | -2.5109 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -2.4873 |
| PLBD1 | phospholipase B domain containing 1 | -2.37345 |
| ZNF274 | zinc finger protein 274 | -2.3473 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -2.2499 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -2.166 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 | -2.1572 |
| CLCC1 | chloride channel CLIC-like 1 | -2.11485 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -2.1118 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase | -2.07525 |
| RAMP3 | receptor (G protein-coupled) activity modifying protein 3 | -2.07385 |
| HHEX | hematopoietically expressed homeobox | -2.05813 |
| CAMTA1 | calmodulin binding transcription activator 1 | -2.0429 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | -2.027 |
