| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2,4-diaminotoluene 2.45 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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86 genes differentially expressed following the CRCGN008_HEPG2_24H:M05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 5.11905 |
| CBR3 | carbonyl reductase 3 | 4.89935 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) | 4.71505 |
| CRTAP | cartilage associated protein | 4.7022 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.66275 |
| HOXA10 | homeobox A10 | 4.55113 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 4.26175 |
| EGF | epidermal growth factor | 4.1372 |
| LOC122526780 | uncharacterized LOC122526780 | 4.1147 |
| BIRC2 | baculoviral IAP repeat containing 2 | 3.9646 |
| GATA3 | GATA binding protein 3 | 3.7977 |
| CHN1 | chimerin 1 | 3.7971 |
| NMU | neuromedin U | 3.78675 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.58495 |
| MAMLD1 | mastermind-like domain containing 1 | 3.29015 |
| CNPY3 | canopy FGF signaling regulator 3 | 3.218 |
| STXBP1 | syntaxin binding protein 1 | 3.11125 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 3.08585 |
| GPATCH8 | G patch domain containing 8 | 3.0855 |
| NOSIP | nitric oxide synthase interacting protein | 2.9565 |
| EMSY | EMSY transcriptional repressor, BRCA2 interacting | 2.92245 |
| SATB1 | SATB homeobox 1 | 2.9078 |
| CEP57 | centrosomal protein 57kDa | 2.80443 |
| MMP1 | matrix metallopeptidase 1 | 2.7797 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.7606 |
| E2F2 | E2F transcription factor 2 | 2.7033 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.6754 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.67473 |
| UVRAG | UV radiation resistance associated | 2.61215 |
| PRKCH | protein kinase C, eta | 2.51683 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 2.51495 |
| CDK19 | cyclin-dependent kinase 19 | 2.37767 |
| JADE2 | jade family PHD finger 2 | 2.33502 |
| GTPBP3 | GTP binding protein 3 (mitochondrial) | 2.30615 |
| HOXA10-HOXA9 | HOXA10-HOXA9 readthrough | 2.29483 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.2885 |
| PKN1 | protein kinase N1 | 2.272 |
| MRPS10 | mitochondrial ribosomal protein S10 | 2.2498 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 2.23055 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | 2.17465 |
| RNASE4 | ribonuclease, RNase A family, 4 | 2.13245 |
| BCL10 | B-cell CLL/lymphoma 10 | 2.13215 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | 2.1238 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 | 2.11345 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.06 |
| EBNA1BP2 | EBNA1 binding protein 2 | 2.0599 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 2.05565 |
| HOXA11 | homeobox A11 | 2.02523 |
| HOXB7 | homeobox B7 | 2.00375 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB1 | cyclin B1 | -7.6766 |
| ZNF586 | zinc finger protein 586 | -6.67935 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -5.14165 |
| NRIP1 | nuclear receptor interacting protein 1 | -4.90783 |
| SPAG4 | sperm associated antigen 4 | -4.6006 |
| CCNB2 | cyclin B2 | -4.5913 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -4.38775 |
| FHL2 | four and a half LIM domains 2 | -4.2808 |
| HMG20B | high mobility group 20B | -3.74307 |
| GNAS | GNAS complex locus | -3.65292 |
| RGS2 | regulator of G-protein signaling 2 | -3.64485 |
| RHEB | Ras homolog enriched in brain | -3.4349 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.18718 |
| RNF167 | ring finger protein 167 | -3.1481 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.91885 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.9076 |
| PCNA | proliferating cell nuclear antigen | -2.64155 |
| MACF1 | microtubule-actin crosslinking factor 1 | -2.61508 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.5807 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.5803 |
| HSPA8 | heat shock 70kDa protein 8 | -2.56468 |
| RBM15 | RNA binding motif protein 15 | -2.39758 |
| CD58 | CD58 molecule | -2.3881 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -2.3551 |
| TGFB3 | transforming growth factor, beta 3 | -2.2454 |
| FASTK | Fas-activated serine/threonine kinase | -2.21878 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.1645 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -2.157 |
| ZNF671 | zinc finger protein 671 | -2.15175 |
| CTSD | cathepsin D | -2.1489 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.14728 |
| RBM34 | RNA binding motif protein 34 | -2.13145 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | -2.11765 |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 | -2.09045 |
| KIFC3 | kinesin family member C3 | -2.05965 |
| RPS5 | ribosomal protein S5 | -2.0533 |
| SLAMF7 | SLAM family member 7 | -2.0058 |
