CRCGN008_HEPG2_24H:M07 Gene Set
Genes
48 genes differentially expressed following the CRCGN008_HEPG2_24H:M07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GPER1
|
G protein-coupled estrogen receptor 1
|
7.30517
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
5.55475
|
|
JADE2
|
jade family PHD finger 2
|
5.00068
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.8691
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.8105
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.6363
|
|
LOC122526780
|
uncharacterized LOC122526780
|
4.02565
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.94557
|
|
APBB2
|
amyloid beta (A4) precursor protein-binding, family B, member 2
|
3.92075
|
|
NOTCH1
|
notch 1
|
3.89615
|
|
EGF
|
epidermal growth factor
|
3.84425
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
3.19075
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.0673
|
|
MAP7
|
microtubule-associated protein 7
|
2.92613
|
|
HEBP1
|
heme binding protein 1
|
2.6717
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.65985
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.53573
|
|
XPO1
|
exportin 1
|
2.4771
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
2.34065
|
|
PCDHB11
|
protocadherin beta 11
|
2.30556
|
|
GATA2
|
GATA binding protein 2
|
2.24262
|
|
NPHS2
|
nephrosis 2, idiopathic, steroid-resistant (podocin)
|
2.21835
|
|
RAMP1
|
receptor (G protein-coupled) activity modifying protein 1
|
2.1566
|
|
MRPL19
|
mitochondrial ribosomal protein L19
|
2.10075
|
|
STXBP2
|
syntaxin binding protein 2
|
2.0987
|
|
PTH1R
|
parathyroid hormone 1 receptor
|
2.0572
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-6.34815
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-5.88105
|
|
EIF4EBP1
|
eukaryotic translation initiation factor 4E binding protein 1
|
-4.7364
|
|
CCNB2
|
cyclin B2
|
-4.6831
|
|
CTSD
|
cathepsin D
|
-4.0659
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-3.90965
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.45867
|
|
PAM16
|
presequence translocase-associated motor 16 homolog (S. cerevisiae)
|
-2.71025
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.6533
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.59482
|
|
KCNJ12
|
potassium channel, inwardly rectifying subfamily J, member 12
|
-2.3467
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.3125
|
|
SREK1IP1
|
SREK1-interacting protein 1
|
-2.2974
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.28095
|
|
TNIK
|
TRAF2 and NCK interacting kinase
|
-2.26495
|
|
DHCR24
|
24-dehydrocholesterol reductase
|
-2.25495
|
|
EXT1
|
exostosin glycosyltransferase 1
|
-2.2142
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-2.21005
|
|
SPINK5
|
serine peptidase inhibitor, Kazal type 5
|
-2.03175
|
|
H1-10
|
H1.10 linker histone
|
-2.0114
|
|
NXF3
|
nuclear RNA export factor 3
|
-2.0068
|
|
RBFOX1
|
RNA binding protein, fox-1 homolog (C. elegans) 1
|
-2.0039
|
