CRCGN008_HEPG2_24H:M09 Gene Set
Genes
51 genes differentially expressed following the CRCGN008_HEPG2_24H:M09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LAGE3
|
L antigen family, member 3
|
5.3953
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
5.19875
|
|
E2F2
|
E2F transcription factor 2
|
4.9582
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.86945
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.8121
|
|
CBR3
|
carbonyl reductase 3
|
4.5887
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
4.28457
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
4.12955
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.6401
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
3.4292
|
|
CHN1
|
chimerin 1
|
3.2416
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.1118
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
3.07375
|
|
MICALL1
|
MICAL-like 1
|
2.8668
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
2.61485
|
|
MYBPC1
|
myosin binding protein C, slow type
|
2.4475
|
|
ZNF589
|
zinc finger protein 589
|
2.38777
|
|
ADGRG1
|
adhesion G protein-coupled receptor G1
|
2.3735
|
|
RAB31
|
RAB31, member RAS oncogene family
|
2.26648
|
|
DDX10
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
|
2.2155
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.20765
|
|
CNIH3
|
cornichon family AMPA receptor auxiliary protein 3
|
2.15415
|
|
NMU
|
neuromedin U
|
2.0921
|
|
HOXC11
|
homeobox C11
|
2.0256
|
|
GPC1
|
glypican 1
|
2.0106
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-6.31385
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.88505
|
|
MAP7
|
microtubule-associated protein 7
|
-4.76757
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-4.67355
|
|
LDHD
|
lactate dehydrogenase D
|
-4.4676
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-4.46645
|
|
SLC35A1
|
solute carrier family 35 (CMP-sialic acid transporter), member A1
|
-4.07495
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-3.1254
|
|
CLIC4
|
chloride intracellular channel 4
|
-3.07052
|
|
LGMN
|
legumain
|
-2.90645
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.89612
|
|
SNX11
|
sorting nexin 11
|
-2.87668
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.54972
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.54905
|
|
CD320
|
CD320 molecule
|
-2.40725
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.32585
|
|
RNF167
|
ring finger protein 167
|
-2.291
|
|
ZNF638
|
zinc finger protein 638
|
-2.24237
|
|
CHST1
|
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
|
-2.2215
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.17968
|
|
TBCC
|
tubulin folding cofactor C
|
-2.10555
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.09365
|
|
TASL
|
TLR adaptor interacting with endolysosomal SLC15A4
|
-2.09185
|
|
FGD2
|
FYVE, RhoGEF and PH domain containing 2
|
-2.0721
|
|
DCK
|
deoxycytidine kinase
|
-2.0674
|
|
CASP5
|
caspase 5, apoptosis-related cysteine peptidase
|
-2.0487
|
