CRCGN008_HEPG2_24H:M10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description barium chloride dihydrate 5.05 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

61 genes differentially expressed following the CRCGN008_HEPG2_24H:M10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 10.0
CCNA1 cyclin A1 5.0057
ANO1 anoctamin 1, calcium activated chloride channel 5.0
UBQLN2 ubiquilin 2 4.9263
CIAO3 cytosolic iron-sulfur assembly component 3 4.78815
NMU neuromedin U 4.66275
MYLK myosin light chain kinase 4.643
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 4.54605
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.4389
HLA-DRA major histocompatibility complex, class II, DR alpha 4.16355
HDGFL3 HDGF like 3 4.14215
PNKP polynucleotide kinase 3'-phosphatase 3.916
PRR15L proline rich 15-like 3.6345
CCL2 chemokine (C-C motif) ligand 2 3.1445
DMAC2L distal membrane arm assembly component 2 like 2.95305
CHN1 chimerin 1 2.7999
SSBP2 single-stranded DNA binding protein 2 2.74317
TIAM1 T-cell lymphoma invasion and metastasis 1 2.40107
ANO10 anoctamin 10 2.3082
TLR4 toll-like receptor 4 2.30535
SOX9 SRY (sex determining region Y)-box 9 2.2943
CTSL cathepsin L 2.2397
CNPY3 canopy FGF signaling regulator 3 2.228
ACP6 acid phosphatase 6, lysophosphatidic 2.22135
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 2.10375
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.0905
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 2.08112
FOS FBJ murine osteosarcoma viral oncogene homolog 2.04915
CGREF1 cell growth regulator with EF-hand domain 1 2.03075
OSBPL11 oxysterol binding protein-like 11 2.0296
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.02445

decreased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen -5.0
ZNF586 zinc finger protein 586 -4.9012
NGRN neugrin, neurite outgrowth associated -4.75525
CD320 CD320 molecule -4.7486
NRIP1 nuclear receptor interacting protein 1 -4.5278
HLA-DMA major histocompatibility complex, class II, DM alpha -4.20265
GNAS GNAS complex locus -4.10432
PRPF4 pre-mRNA processing factor 4 -3.70222
HSPA8 heat shock 70kDa protein 8 -3.07088
CHEK1 checkpoint kinase 1 -3.0277
OXA1L oxidase (cytochrome c) assembly 1-like -2.80435
RNF167 ring finger protein 167 -2.71715
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -2.58208
ABHD14A abhydrolase domain containing 14A -2.50575
PCDHB3 protocadherin beta 3 -2.46675
PDS5A PDS5 cohesin associated factor A -2.44226
DENND1A DENN/MADD domain containing 1A -2.44145
ZSCAN9 zinc finger and SCAN domain containing 9 -2.36065
GLOD4 glyoxalase domain containing 4 -2.3235
NR4A2 nuclear receptor subfamily 4, group A, member 2 -2.21993
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 -2.1958
BSG basigin (Ok blood group) -2.18265
PCDHB13 protocadherin beta 13 -2.1799
ZKSCAN7 zinc finger with KRAB and SCAN domains 7 -2.16805
FKTN fukutin -2.13785
NUP43 nucleoporin 43kDa -2.10805
ZNF165 zinc finger protein 165 -2.0551
CCDC169-SOHLH2 CCDC169-SOHLH2 readthrough -2.0534
CCN5 cellular communication network factor 5 -2.0169
TCEA2 transcription elongation factor A (SII), 2 -2.0092