| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | barium chloride dihydrate 5.05 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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61 genes differentially expressed following the CRCGN008_HEPG2_24H:M10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 10.0 |
| CCNA1 | cyclin A1 | 5.0057 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 5.0 |
| UBQLN2 | ubiquilin 2 | 4.9263 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.78815 |
| NMU | neuromedin U | 4.66275 |
| MYLK | myosin light chain kinase | 4.643 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.54605 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.4389 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 4.16355 |
| HDGFL3 | HDGF like 3 | 4.14215 |
| PNKP | polynucleotide kinase 3'-phosphatase | 3.916 |
| PRR15L | proline rich 15-like | 3.6345 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.1445 |
| DMAC2L | distal membrane arm assembly component 2 like | 2.95305 |
| CHN1 | chimerin 1 | 2.7999 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.74317 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.40107 |
| ANO10 | anoctamin 10 | 2.3082 |
| TLR4 | toll-like receptor 4 | 2.30535 |
| SOX9 | SRY (sex determining region Y)-box 9 | 2.2943 |
| CTSL | cathepsin L | 2.2397 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.228 |
| ACP6 | acid phosphatase 6, lysophosphatidic | 2.22135 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 2.10375 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.0905 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 2.08112 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 2.04915 |
| CGREF1 | cell growth regulator with EF-hand domain 1 | 2.03075 |
| OSBPL11 | oxysterol binding protein-like 11 | 2.0296 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.02445 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -5.0 |
| ZNF586 | zinc finger protein 586 | -4.9012 |
| NGRN | neugrin, neurite outgrowth associated | -4.75525 |
| CD320 | CD320 molecule | -4.7486 |
| NRIP1 | nuclear receptor interacting protein 1 | -4.5278 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -4.20265 |
| GNAS | GNAS complex locus | -4.10432 |
| PRPF4 | pre-mRNA processing factor 4 | -3.70222 |
| HSPA8 | heat shock 70kDa protein 8 | -3.07088 |
| CHEK1 | checkpoint kinase 1 | -3.0277 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.80435 |
| RNF167 | ring finger protein 167 | -2.71715 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | -2.58208 |
| ABHD14A | abhydrolase domain containing 14A | -2.50575 |
| PCDHB3 | protocadherin beta 3 | -2.46675 |
| PDS5A | PDS5 cohesin associated factor A | -2.44226 |
| DENND1A | DENN/MADD domain containing 1A | -2.44145 |
| ZSCAN9 | zinc finger and SCAN domain containing 9 | -2.36065 |
| GLOD4 | glyoxalase domain containing 4 | -2.3235 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -2.21993 |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 | -2.1958 |
| BSG | basigin (Ok blood group) | -2.18265 |
| PCDHB13 | protocadherin beta 13 | -2.1799 |
| ZKSCAN7 | zinc finger with KRAB and SCAN domains 7 | -2.16805 |
| FKTN | fukutin | -2.13785 |
| NUP43 | nucleoporin 43kDa | -2.10805 |
| ZNF165 | zinc finger protein 165 | -2.0551 |
| CCDC169-SOHLH2 | CCDC169-SOHLH2 readthrough | -2.0534 |
| CCN5 | cellular communication network factor 5 | -2.0169 |
| TCEA2 | transcription elongation factor A (SII), 2 | -2.0092 |