| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | barium chloride dihydrate 2.52 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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58 genes differentially expressed following the CRCGN008_HEPG2_24H:M11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHN1 | chimerin 1 | 6.41465 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.5244 |
| MYLK | myosin light chain kinase | 5.4984 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.2797 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 5.1308 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.8494 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.69835 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.65105 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 4.64285 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.4966 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 4.2941 |
| SMAD3 | SMAD family member 3 | 4.17666 |
| PLSCR1 | phospholipid scramblase 1 | 3.64298 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.90625 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.87713 |
| PLSCR3 | phospholipid scramblase 3 | 2.70707 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.6544 |
| TLK2 | tousled-like kinase 2 | 2.62387 |
| GPATCH8 | G patch domain containing 8 | 2.61867 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.5668 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.51192 |
| ZNF589 | zinc finger protein 589 | 2.4933 |
| CCNF | cyclin F | 2.44578 |
| WASF3 | WAS protein family, member 3 | 2.41825 |
| TMEM14A | transmembrane protein 14A | 2.27175 |
| TXNL4B | thioredoxin-like 4B | 2.2246 |
| USP6NL | USP6 N-terminal like | 2.1825 |
| GLI3 | GLI family zinc finger 3 | 2.15385 |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 | 2.09065 |
| NECTIN4 | nectin cell adhesion molecule 4 | 2.05135 |
| TMPRSS11D | transmembrane protease, serine 11D | 2.01755 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -9.43755 |
| EGF | epidermal growth factor | -5.49975 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -5.1774 |
| NVL | nuclear VCP-like | -3.93515 |
| HMG20B | high mobility group 20B | -3.63232 |
| DERA | deoxyribose-phosphate aldolase (putative) | -3.52065 |
| GNAS | GNAS complex locus | -3.51216 |
| DEAF1 | DEAF1 transcription factor | -2.7113 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.5976 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.57985 |
| LGMN | legumain | -2.48115 |
| IFT70A | intraflagellar transport 70A | -2.4386 |
| SLC12A1 | solute carrier family 12 (sodium/potassium/chloride transporter), member 1 | -2.41865 |
| TXNDC9 | thioredoxin domain containing 9 | -2.31315 |
| GDF15 | growth differentiation factor 15 | -2.2656 |
| NOL4 | nucleolar protein 4 | -2.26405 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -2.21665 |
| TRAPPC13 | trafficking protein particle complex 13 | -2.19685 |
| POMK | protein-O-mannose kinase | -2.15503 |
| HSF2BP | heat shock transcription factor 2 binding protein | -2.1074 |
| RRAS | related RAS viral (r-ras) oncogene homolog | -2.0976 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -2.08958 |
| KCNJ1 | potassium channel, inwardly rectifying subfamily J, member 1 | -2.0886 |
| ITGB6 | integrin, beta 6 | -2.07312 |
| SLC30A4 | solute carrier family 30 (zinc transporter), member 4 | -2.00995 |
| CDC37L1 | cell division cycle 37-like 1 | -2.00785 |
| KNG1 | kininogen 1 | -2.00375 |
