CRCGN008_HEPG2_24H:M13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-(chloromethyl)pyridine.hcl 39.4 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

535 genes differentially expressed following the CRCGN008_HEPG2_24H:M13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MYLK myosin light chain kinase 10.0
HLA-DMA major histocompatibility complex, class II, DM alpha 10.0
CHMP6 charged multivesicular body protein 6 10.0
UBQLN2 ubiquilin 2 10.0
ABHD6 abhydrolase domain containing 6 9.1971
KCNK1 potassium channel, two pore domain subfamily K, member 1 8.69325
FZD7 frizzled class receptor 7 8.5104
CHN1 chimerin 1 7.9838
CDPF1 cysteine-rich, DPF motif domain containing 1 7.5748
CYCS cytochrome c, somatic 7.3925
PFKL phosphofructokinase, liver 6.55057
FCHO1 FCH domain only 1 6.1614
SRC SRC proto-oncogene, non-receptor tyrosine kinase 5.85075
CAPN1 calpain 1, (mu/I) large subunit 5.6375
TBP TATA box binding protein 5.1848
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 4.7838
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 4.2942
CNPY3 canopy FGF signaling regulator 3 3.9586
ZNF395 zinc finger protein 395 3.90697
PLPPR4 phospholipid phosphatase related 4 3.8574
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 3.818
PTPN6 protein tyrosine phosphatase, non-receptor type 6 3.7935
PACRG PARK2 co-regulated 3.7885
KIF20A kinesin family member 20A 3.7822
LY6H lymphocyte antigen 6 complex, locus H 3.7125
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 3.6901
SH3GLB2 SH3-domain GRB2-like endophilin B2 3.5538
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 3.4636
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 3.40187
CCP110 centriolar coiled coil protein 110kDa 3.3846
ANO1 anoctamin 1, calcium activated chloride channel 3.3799
ARF5 ADP-ribosylation factor 5 3.3216
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 3.3035
PDE11A phosphodiesterase 11A 3.2789
DNM2 dynamin 2 3.2551
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 3.2308
GATD3 glutamine amidotransferase class 1 domain containing 3 3.21045
ZC2HC1A zinc finger, C2HC-type containing 1A 3.1834
TRIM68 tripartite motif containing 68 3.1397
DEFA5 defensin, alpha 5, Paneth cell-specific 3.1328
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 3.1213
ANKMY2 ankyrin repeat and MYND domain containing 2 3.1081
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 3.0862
NUTF2 nuclear transport factor 2 3.079
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 3.0616
FKBP8 FK506 binding protein 8, 38kDa 3.04055
ANO10 anoctamin 10 3.0378
THAP11 THAP domain containing 11 3.0179
STUM stum, mechanosensory transduction mediator homolog 3.0005
PTK2 protein tyrosine kinase 2 2.9986
ZNF282 zinc finger protein 282 2.9719
CORO7-PAM16 CORO7-PAM16 readthrough 2.9541
ARFRP1 ADP-ribosylation factor related protein 1 2.94715
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 2.9453
HAS2 hyaluronan synthase 2 2.9417
LOXL2 lysyl oxidase-like 2 2.90747
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 2.8927
GDF3 growth differentiation factor 3 2.8925
GSTK1 glutathione S-transferase kappa 1 2.8729
SPACA9 sperm acrosome associated 9 2.8714
AP3M2 adaptor-related protein complex 3, mu 2 subunit 2.8679
WNT16 wingless-type MMTV integration site family, member 16 2.8642
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 2.81377
HSF4 heat shock transcription factor 4 2.7976
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) 2.7814
LAMP5 lysosomal-associated membrane protein family, member 5 2.7659
LARP6 La ribonucleoprotein domain family, member 6 2.7608
NMU neuromedin U 2.7453
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 2.7328
UBE2O ubiquitin-conjugating enzyme E2O 2.7091
ZNF280B zinc finger protein 280B 2.7053
FRS3 fibroblast growth factor receptor substrate 3 2.6957
GAL3ST1 galactose-3-O-sulfotransferase 1 2.6918
TLN2 talin 2 2.68875
CSRP2 cysteine and glycine-rich protein 2 2.68415
CABIN1 calcineurin binding protein 1 2.68075
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) 2.6805
CAPN6 calpain 6 2.677
CREB3L1 cAMP responsive element binding protein 3-like 1 2.67155
HPCA hippocalcin 2.6692
MAP6D1 MAP6 domain containing 1 2.6647
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 2.6576
HOXA10 homeobox A10 2.65215
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa 2.6422
RUSF1 RUS family member 1 2.63985
DEFA6 defensin, alpha 6, Paneth cell-specific 2.6382
GPR162 G protein-coupled receptor 162 2.6037
CEPT1 choline/ethanolamine phosphotransferase 1 2.5948
XPO7 exportin 7 2.5947
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 2.5909
SYNGR2 synaptogyrin 2 2.5877
MAGED4B melanoma antigen family D4B 2.5755
CCND1 cyclin D1 2.5754
LOC128966586 pepsin A-4-like 2.5746
DNAAF3 dynein, axonemal, assembly factor 3 2.5716
MUC2 mucin 2, oligomeric mucus/gel-forming 2.5696
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 2.566
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 2.5636
HILPDA hypoxia inducible lipid droplet-associated 2.5594
NRBP1 nuclear receptor binding protein 1 2.5462
SH3GL3 SH3-domain GRB2-like 3 2.5448
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 2.5447
LY6E lymphocyte antigen 6 complex, locus E 2.5355
OMG oligodendrocyte myelin glycoprotein 2.5349
ADM adrenomedullin 2.5176
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 2.5157
NGF nerve growth factor (beta polypeptide) 2.5044
ICAM5 intercellular adhesion molecule 5, telencephalin 2.4961
ELP3 elongator acetyltransferase complex subunit 3 2.4922
CCL2 chemokine (C-C motif) ligand 2 2.4899
MXRA8 matrix-remodelling associated 8 2.485
MNX1 motor neuron and pancreas homeobox 1 2.4848
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase) 2.4779
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 2.4777
PCCA propionyl CoA carboxylase, alpha polypeptide 2.4744
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 2.4736
LOC124900388 uncharacterized LOC124900388 2.4716
CDKL3 cyclin-dependent kinase-like 3 2.4677
MAMLD1 mastermind-like domain containing 1 2.4605
DZIP3 DAZ interacting zinc finger protein 3 2.4583
OLFML3 olfactomedin-like 3 2.4556
TUBB4A tubulin, beta 4A class IVa 2.4554
ADRB2 adrenoceptor beta 2, surface 2.4537
CALR calreticulin 2.45033
CCNC cyclin C 2.45
PHF24 PHD finger protein 24 2.44825
SLCO1C1 solute carrier organic anion transporter family, member 1C1 2.4459
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 2.4442
DAAM2 dishevelled associated activator of morphogenesis 2 2.4429
PRR13 proline rich 13 2.4399
CLCA1 chloride channel accessory 1 2.4392
DCTN1 dynactin 1 2.4349
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 2.4321
LY6G6C lymphocyte antigen 6 complex, locus G6C 2.4294
NBAS neuroblastoma amplified sequence 2.4255
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 2.424
MAP3K14 mitogen-activated protein kinase kinase kinase 14 2.4223
ZNF385D zinc finger protein 385D 2.4145
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 2.4142
SEM1 SEM1 26S proteasome subunit 2.4044
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 2.4041
LOC105379278 uncharacterized LOC105379278 2.4031
MTERF3 mitochondrial transcription termination factor 3 2.4016
ADGRA2 adhesion G protein-coupled receptor A2 2.4013
SAMD14 sterile alpha motif domain containing 14 2.3992
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 2.3948
TRPM2 transient receptor potential cation channel, subfamily M, member 2 2.3947
HSPA1A heat shock 70kDa protein 1A 2.3935
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 2.3897
VEGFB vascular endothelial growth factor B 2.3868
NRG2 neuregulin 2 2.3864
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 2.3821
USB1 U6 snRNA biogenesis 1 2.3814
DNM3 dynamin 3 2.3774
COL7A1 collagen, type VII, alpha 1 2.37735
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 2.3704
E2F2 E2F transcription factor 2 2.3698
HBE1 hemoglobin, epsilon 1 2.3664
FCGBP Fc fragment of IgG binding protein 2.3616
HSPA12A heat shock 70kDa protein 12A 2.3584
SH2D4A SH2 domain containing 4A 2.347
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) 2.3362
HLA-DMB major histocompatibility complex, class II, DM beta 2.33
SCN3B sodium channel, voltage gated, type III beta subunit 2.32945
REG1A regenerating islet-derived 1 alpha 2.3289
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 2.3285
BSN bassoon presynaptic cytomatrix protein 2.3283
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B 2.3246
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 2.3242
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.324
CRLF1 cytokine receptor-like factor 1 2.3192
PDE2A phosphodiesterase 2A, cGMP-stimulated 2.319
MPST mercaptopyruvate sulfurtransferase 2.3181
HSPB2 heat shock 27kDa protein 2 2.3149
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 2.3141
THRAP3 thyroid hormone receptor associated protein 3 2.3118
HACL2 2-hydroxyacyl-CoA lyase 2 2.311
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.3098
CPVL carboxypeptidase, vitellogenic-like 2.3075
ENY2 enhancer of yellow 2 homolog (Drosophila) 2.3024
FOXO3 forkhead box O3 2.29425
LIN7B lin-7 homolog B (C. elegans) 2.2935
FLNC filamin C, gamma 2.2911
CAMTA1 calmodulin binding transcription activator 1 2.2894
CDX2 caudal type homeobox 2 2.2817
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 2.2796
FOXH1 forkhead box H1 2.2747
LARP7 La ribonucleoprotein domain family, member 7 2.2747
CREG1 cellular repressor of E1A-stimulated genes 1 2.2728
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) 2.2649
CD207 CD207 molecule, langerin 2.2649
WDR3 WD repeat domain 3 2.2629
H1-10 H1.10 linker histone 2.2611
CPQ carboxypeptidase Q 2.2597
RNF187 ring finger protein 187 2.2588
MOCS1 molybdenum cofactor synthesis 1 2.25775
ZNF365 zinc finger protein 365 2.2561
DMTN dematin actin binding protein 2.2513
PRRX2 paired related homeobox 2 2.2493
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 2.2492
PDE9A phosphodiesterase 9A 2.2433
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 2.2432
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 2.2389
L1TD1 LINE-1 type transposase domain containing 1 2.2333
RGS9BP regulator of G protein signaling 9 binding protein 2.2301
SMYD5 SMYD family member 5 2.2297
SHARPIN SHANK-associated RH domain interactor 2.2278
HOXA4 homeobox A4 2.2254
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 2.2237
GIPR gastric inhibitory polypeptide receptor 2.2233
MRPS22 mitochondrial ribosomal protein S22 2.2108
WNT5B wingless-type MMTV integration site family, member 5B 2.2101
KHK ketohexokinase (fructokinase) 2.2067
PCYT2 phosphate cytidylyltransferase 2, ethanolamine 2.2064
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 2.2032
WFS1 Wolfram syndrome 1 (wolframin) 2.2025
H1-4 H1.4 linker histone, cluster member 2.2013
GIPC1 GIPC PDZ domain containing family, member 1 2.2013
ADTRP androgen-dependent TFPI-regulating protein 2.1972
PRDM16 PR domain containing 16 2.1963
NIPSNAP2 nipsnap homolog 2 2.1929
NKX3-2 NK3 homeobox 2 2.1896
FGD1 FYVE, RhoGEF and PH domain containing 1 2.1894
NHEJ1 nonhomologous end-joining factor 1 2.1872
EIF3E eukaryotic translation initiation factor 3, subunit E 2.1828
PFKP phosphofructokinase, platelet 2.1819
EPHA4 EPH receptor A4 2.1818
PTP4A3 protein tyrosine phosphatase type IVA, member 3 2.1786
MAGEL2 melanoma antigen family L2 2.1777
CCDC68 coiled-coil domain containing 68 2.177
CCKBR cholecystokinin B receptor 2.1761
DOK4 docking protein 4 2.17457
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 2.17386
CCL24 chemokine (C-C motif) ligand 24 2.173
DOCK3 dedicator of cytokinesis 3 2.1686
MAST3 microtubule associated serine/threonine kinase 3 2.1669
FGF9 fibroblast growth factor 9 2.1653
EPS8L3 EPS8-like 3 2.1635
SORBS3 sorbin and SH3 domain containing 3 2.163
COL5A3 collagen, type V, alpha 3 2.16275
ATOH1 atonal homolog 1 (Drosophila) 2.1622
FAM246A family with sequence similarity 246 member A 2.1581
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) 2.1549
ASTN1 astrotactin 1 2.1514
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1 2.1507
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 2.15
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) 2.1489
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 2.1486
BGLAP bone gamma-carboxyglutamate (gla) protein 2.1437
PRRC2A proline-rich coiled-coil 2A 2.14363
CA14 carbonic anhydrase XIV 2.143
TBPL1 TBP-like 1 2.1423
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 2.142
TPRA1 transmembrane protein, adipocyte asscociated 1 2.1341
ARL2 ADP-ribosylation factor-like 2 2.1329
CHMP1A charged multivesicular body protein 1A 2.1307
MAGEA9B melanoma antigen family A9B 2.1305
LRRC49 leucine rich repeat containing 49 2.1202
RRAGB Ras-related GTP binding B 2.1139
CNTNAP1 contactin associated protein 1 2.1137
KIFAP3 kinesin-associated protein 3 2.1114
TMEM209 transmembrane protein 209 2.106
ZFHX4 zinc finger homeobox 4 2.1055
FABP6 fatty acid binding protein 6, ileal 2.1051
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 2.1006
CRYGD crystallin, gamma D 2.0951
SHISAL1 shisa like 1 2.0905
TECR trans-2,3-enoyl-CoA reductase 2.0899
FAM234B family with sequence similarity 234 member B 2.0883
CPEB1 cytoplasmic polyadenylation element binding protein 1 2.0846
ENPEP glutamyl aminopeptidase (aminopeptidase A) 2.0825
SLC30A10 solute carrier family 30, member 10 2.0794
GBX2 gastrulation brain homeobox 2 2.0793
NELL2 NEL-like 2 (chicken) 2.0782
POT1 protection of telomeres 1 2.0764
PENK proenkephalin 2.0753
PRKCB protein kinase C, beta 2.0747
HHAT hedgehog acyltransferase 2.0713
ZNF672 zinc finger protein 672 2.071
GTF2A1 general transcription factor IIA, 1, 19/37kDa 2.07
SNTA1 syntrophin, alpha 1 2.0691
TMPRSS4 transmembrane protease, serine 4 2.06907
ARPC4-TTLL3 ARPC4-TTLL3 readthrough 2.06633
PDIA4 protein disulfide isomerase family A, member 4 2.06585
DKK4 dickkopf WNT signaling pathway inhibitor 4 2.0634
PTN pleiotrophin 2.06227
NAP1L2 nucleosome assembly protein 1-like 2 2.0607
ATP5F1D ATP synthase F1 subunit delta 2.05885
ZFC3H1 zinc finger, C3H1-type containing 2.0515
NMRK2 nicotinamide riboside kinase 2 2.0489
LAIR2 leukocyte-associated immunoglobulin-like receptor 2 2.0488
ITGB7 integrin, beta 7 2.0461
LGALS9C lectin, galactoside-binding, soluble, 9C 2.0459
SV2B synaptic vesicle glycoprotein 2B 2.0448
HMGA1 high mobility group AT-hook 1 2.04445
CDT1 chromatin licensing and DNA replication factor 1 2.0406
MAPK3 mitogen-activated protein kinase 3 2.039
IGSF1 immunoglobulin superfamily, member 1 2.0376
PPIC peptidylprolyl isomerase C (cyclophilin C) 2.03705
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 2.0367
ADGRG2 adhesion G protein-coupled receptor G2 2.0358
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 2.0356
CNPY4 canopy FGF signaling regulator 4 2.0354
CABP1 calcium binding protein 1 2.0338
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 2.0328
TRAPPC10 trafficking protein particle complex 10 2.03085
ANXA13 annexin A13 2.0304
RIN1 Ras and Rab interactor 1 2.0296
PSKH1 protein serine kinase H1 2.0262
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 2.0248
SDC2 syndecan 2 2.02327
NFU1 NFU1 iron-sulfur cluster scaffold 2.0228
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 2.0227
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 2.0214
THNSL1 threonine synthase-like 1 (S. cerevisiae) 2.0195
SCML2 sex comb on midleg-like 2 (Drosophila) 2.0182
SERGEF secretion regulating guanine nucleotide exchange factor 2.018
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma 2.0171
LOX lysyl oxidase 2.01487
SEPTIN5 septin 5 2.0131
GET3 guided entry of tail-anchored proteins factor 3, ATPase 2.013
CDK5 cyclin-dependent kinase 5 2.011
NRGN neurogranin (protein kinase C substrate, RC3) 2.01
GPR20 G protein-coupled receptor 20 2.009
TEX11 testis expressed 11 2.0056
KLHDC3 kelch domain containing 3 2.0044
ZNF536 zinc finger protein 536 2.0

decreased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen -10.0
NGRN neugrin, neurite outgrowth associated -10.0
TUBB6 tubulin, beta 6 class V -10.0
FASTKD5 FAST kinase domains 5 -9.602
MAP7 microtubule-associated protein 7 -8.57077
ACAA1 acetyl-CoA acyltransferase 1 -6.64475
CLIC4 chloride intracellular channel 4 -6.4569
RGS2 regulator of G-protein signaling 2 -5.8901
SATB1 SATB homeobox 1 -5.0661
TXNRD1 thioredoxin reductase 1 -4.8707
CCNB1 cyclin B1 -4.8345
BTK Bruton agammaglobulinemia tyrosine kinase -4.644
CRK v-crk avian sarcoma virus CT10 oncogene homolog -4.63253
ZW10 zw10 kinetochore protein -4.6175
ERBB2 erb-b2 receptor tyrosine kinase 2 -4.2527
PYGB phosphorylase, glycogen; brain -4.221
CHIC2 cysteine-rich hydrophobic domain 2 -4.2067
TXNDC9 thioredoxin domain containing 9 -4.02435
GLOD4 glyoxalase domain containing 4 -3.6373
PANK2 pantothenate kinase 2 -3.6362
CPA4 carboxypeptidase A4 -3.5421
CUL4B cullin 4B -3.5092
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase -3.4025
PRKCH protein kinase C, eta -3.37005
HAO2 hydroxyacid oxidase 2 (long chain) -3.3545
OSBPL9 oxysterol binding protein-like 9 -3.2657
MARCO macrophage receptor with collagenous structure -3.2534
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 -3.2422
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase -3.1662
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -3.10535
ZNF8 zinc finger protein 8 -3.0626
KIF16B kinesin family member 16B -3.0576
DHCR24 24-dehydrocholesterol reductase -3.0158
DSTN destrin (actin depolymerizing factor) -2.94935
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 -2.9394
APOF apolipoprotein F -2.868
AKR1C1 aldo-keto reductase family 1, member C1 -2.86386
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7 -2.8551
WNT2 wingless-type MMTV integration site family member 2 -2.8383
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 -2.8372
IRX5 iroquois homeobox 5 -2.8293
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.8064
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -2.8024
FCN3 ficolin (collagen/fibrinogen domain containing) 3 -2.7997
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -2.7445
ZNF324 zinc finger protein 324 -2.7409
KHDC4 KH domain containing 4, pre-mRNA splicing factor -2.7168
GLRX2 glutaredoxin 2 -2.6963
NOP10 NOP10 ribonucleoprotein -2.6749
ERMP1 endoplasmic reticulum metallopeptidase 1 -2.6657
HAPSTR1 HUWE1 associated protein modifying stress responses -2.6532
KRT7 keratin 7, type II -2.6057
RPS5 ribosomal protein S5 -2.5997
TIMP1 TIMP metallopeptidase inhibitor 1 -2.5985
AZGP1 alpha-2-glycoprotein 1, zinc-binding -2.5973
NR4A2 nuclear receptor subfamily 4, group A, member 2 -2.57977
ATXN2 ataxin 2 -2.5754
UBAP1 ubiquitin associated protein 1 -2.56305
HOXA5 homeobox A5 -2.5606
AP5S1 adaptor-related protein complex 5, sigma 1 subunit -2.5451
TCIM transcriptional and immune response regulator -2.5273
ITPRID2 ITPR interacting domain containing 2 -2.5084
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -2.5077
SFTPD surfactant protein D -2.5063
FAM8A1 family with sequence similarity 8, member A1 -2.4986
RBFA ribosome binding factor A (putative) -2.4922
PLA2G12A phospholipase A2, group XIIA -2.49
DDRGK1 DDRGK domain containing 1 -2.4873
PON3 paraoxonase 3 -2.4762
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) -2.4746
GPR87 G protein-coupled receptor 87 -2.465
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 -2.456
CLOCK clock circadian regulator -2.4446
MRM3 mitochondrial rRNA methyltransferase 3 -2.4426
RHOH ras homolog family member H -2.4402
CCDC6 coiled-coil domain containing 6 -2.4369
SESN1 sestrin 1 -2.4335
SFTPC surfactant protein C -2.41578
BCLAF1 BCL2-associated transcription factor 1 -2.41315
SOCS6 suppressor of cytokine signaling 6 -2.40385
C1RL complement component 1, r subcomponent-like -2.4024
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) -2.3919
CDC73 cell division cycle 73 -2.3875
EVL Enah/Vasp-like -2.3854
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -2.3805
HECA headcase homolog (Drosophila) -2.37165
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 -2.3543
SCRIB scribbled planar cell polarity protein -2.3462
GCLC glutamate-cysteine ligase, catalytic subunit -2.3338
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.3295
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 -2.3242
BAG1 BCL2-associated athanogene -2.3229
AQP4 aquaporin 4 -2.31343
OCLN occludin -2.313
ZNF133 zinc finger protein 133 -2.29925
MCL1 myeloid cell leukemia 1 -2.2972
YBX3 Y box binding protein 3 -2.2961
ESRP1 epithelial splicing regulatory protein 1 -2.2942
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -2.2928
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -2.2882
ABHD18 abhydrolase domain containing 18 -2.2863
TMEM43 transmembrane protein 43 -2.2804
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 -2.2789
RGPD2 RANBP2-like and GRIP domain containing 2 -2.2732
COMP cartilage oligomeric matrix protein -2.263
TASP1 taspase, threonine aspartase, 1 -2.2599
TPSAB1 tryptase alpha/beta 1 -2.25452
NXT1 nuclear transport factor 2-like export factor 1 -2.2537
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 -2.2496
RNF103 ring finger protein 103 -2.241
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 -2.23925
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 -2.2356
PPP4R3A protein phosphatase 4 regulatory subunit 3A -2.23405
CD59 CD59 molecule, complement regulatory protein -2.23252
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) -2.2313
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 -2.2279
MICALL1 MICAL-like 1 -2.2277
ERC1 ELKS/RAB6-interacting/CAST family member 1 -2.2246
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.2113
CXCL6 chemokine (C-X-C motif) ligand 6 -2.1931
FBXO28 F-box protein 28 -2.186
SPAG1 sperm associated antigen 1 -2.1839
ZNF304 zinc finger protein 304 -2.1831
TATDN2 TatD DNase domain containing 2 -2.179
TMEM165 transmembrane protein 165 -2.1743
NR4A1 nuclear receptor subfamily 4, group A, member 1 -2.17145
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 -2.1703
FABP4 fatty acid binding protein 4, adipocyte -2.1701
CCDC69 coiled-coil domain containing 69 -2.1687
CELA2B chymotrypsin-like elastase family, member 2B -2.1683
ZBTB16 zinc finger and BTB domain containing 16 -2.1661
CASP6 caspase 6, apoptosis-related cysteine peptidase -2.1609
TAOK1 TAO kinase 1 -2.16
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -2.1585
NTAN1 N-terminal asparagine amidase -2.1565
SEC23B Sec23 homolog B (S. cerevisiae) -2.1555
DCTN3 dynactin 3 (p22) -2.1546
SLC43A3 solute carrier family 43, member 3 -2.1527
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 -2.1524
MED17 mediator complex subunit 17 -2.1488
UNC13B unc-13 homolog B (C. elegans) -2.1473
FOXO1 forkhead box O1 -2.14445
CALCRL calcitonin receptor-like -2.1443
RGS18 regulator of G-protein signaling 18 -2.1435
ZNF587B zinc finger protein 587B -2.1414
TMEM230 transmembrane protein 230 -2.1321
DUS1L dihydrouridine synthase 1-like (S. cerevisiae) -2.132
HSPA6 heat shock 70kDa protein 6 (HSP70B') -2.13155
CEP76 centrosomal protein 76kDa -2.12705
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 -2.1254
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -2.1242
SIRT1 sirtuin 1 -2.1227
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -2.1224
ZNF419 zinc finger protein 419 -2.12235
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12) -2.1132
TUG1 taurine up-regulated 1 (non-protein coding) -2.10523
ECM1 extracellular matrix protein 1 -2.1042
VEZF1 vascular endothelial zinc finger 1 -2.10177
IL12RB2 interleukin 12 receptor, beta 2 -2.1014
CYB5A cytochrome b5 type A (microsomal) -2.0924
AKR1C3 aldo-keto reductase family 1, member C3 -2.0913
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -2.0899
LAX1 lymphocyte transmembrane adaptor 1 -2.0882
RAB13 RAB13, member RAS oncogene family -2.0875
PHACTR4 phosphatase and actin regulator 4 -2.086
ZNF587 zinc finger protein 587 -2.0859
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -2.0847
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -2.0847
CCL19 chemokine (C-C motif) ligand 19 -2.0836
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.0794
TM6SF1 transmembrane 6 superfamily member 1 -2.0771
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -2.0722
CENPC centromere protein C -2.0691
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C -2.0687
GK glycerol kinase -2.06738
IL23A interleukin 23, alpha subunit p19 -2.0651
SFRP4 secreted frizzled-related protein 4 -2.0633
CXCL13 chemokine (C-X-C motif) ligand 13 -2.0629
SPRING1 SREBF pathway regulator in golgi 1 -2.0619
TRAIP TRAF interacting protein -2.0587
TOB2 transducer of ERBB2, 2 -2.05505
RNF139 ring finger protein 139 -2.0548
TTC9 tetratricopeptide repeat domain 9 -2.0492
MFSD6 major facilitator superfamily domain containing 6 -2.0491
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -2.04833
ZNF532 zinc finger protein 532 -2.0468
ING1 inhibitor of growth family, member 1 -2.04513
FAAP24 FA core complex associated protein 24 -2.045
SCYL2 SCY1-like 2 (S. cerevisiae) -2.0432
MBIP MAP3K12 binding inhibitory protein 1 -2.0421
CAVIN1 caveolae associated protein 1 -2.04205
AVPI1 arginine vasopressin-induced 1 -2.0406
KIAA0319L KIAA0319-like -2.0356
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) -2.0343
UNC50 unc-50 homolog (C. elegans) -2.0328
MAVS mitochondrial antiviral signaling protein -2.0311
ATRN attractin -2.02765
NOTCH2 notch 2 -2.02747
ACSL1 acyl-CoA synthetase long-chain family member 1 -2.02725
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -2.0248
ASF1A anti-silencing function 1A histone chaperone -2.018
NNMT nicotinamide N-methyltransferase -2.0098
CLDN1 claudin 1 -2.0097
TSPAN1 tetraspanin 1 -2.0089
FHL2 four and a half LIM domains 2 -2.0083
IRF7 interferon regulatory factor 7 -2.0077
HMGA2 high mobility group AT-hook 2 -2.0013
CSRNP2 cysteine-serine-rich nuclear protein 2 -2.0011