| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2-(chloromethyl)pyridine.hcl 1.23 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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53 genes differentially expressed following the CRCGN008_HEPG2_24H:M18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADRB2 | adrenoceptor beta 2, surface | 5.98865 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.559 |
| CHMP6 | charged multivesicular body protein 6 | 5.2868 |
| LOC122526780 | uncharacterized LOC122526780 | 5.12635 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.63415 |
| SSBP2 | single-stranded DNA binding protein 2 | 4.32942 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 4.06238 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.794 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.67677 |
| EGF | epidermal growth factor | 3.615 |
| PRR15L | proline rich 15-like | 3.17015 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 3.04955 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 2.7672 |
| GPATCH8 | G patch domain containing 8 | 2.71985 |
| JADE2 | jade family PHD finger 2 | 2.70813 |
| CYCS | cytochrome c, somatic | 2.6178 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 2.4789 |
| ZNF589 | zinc finger protein 589 | 2.43852 |
| SMAD3 | SMAD family member 3 | 2.41459 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.37957 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.3547 |
| HEBP1 | heme binding protein 1 | 2.26615 |
| TXNL4B | thioredoxin-like 4B | 2.259 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 2.16397 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 2.0951 |
| CENPU | centromere protein U | 2.04555 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) | 2.03135 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | 2.01395 |
| Symbol | Name | Standardized Value |
|---|---|---|
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.53955 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -5.7047 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -5.63405 |
| SLC35F2 | solute carrier family 35, member F2 | -5.48505 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -4.81015 |
| VAT1 | vesicle amine transport 1 | -4.55925 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.1019 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -3.26593 |
| ZW10 | zw10 kinetochore protein | -2.57295 |
| GET1 | guided entry of tail-anchored proteins factor 1 | -2.50235 |
| RBM34 | RNA binding motif protein 34 | -2.47405 |
| FASTKD5 | FAST kinase domains 5 | -2.4702 |
| MACF1 | microtubule-actin crosslinking factor 1 | -2.45524 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | -2.32705 |
| CCDC70 | coiled-coil domain containing 70 | -2.21255 |
| HAND1 | heart and neural crest derivatives expressed 1 | -2.2073 |
| RNF167 | ring finger protein 167 | -2.164 |
| AKR1C4 | aldo-keto reductase family 1, member C4 | -2.159 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | -2.1326 |
| GMEB2 | glucocorticoid modulatory element binding protein 2 | -2.12815 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) | -2.10195 |
| CFHR3 | complement factor H-related 3 | -2.06665 |
| CTSS | cathepsin S | -2.06003 |
| C8A | complement component 8, alpha polypeptide | -2.0109 |
| M6PR | mannose-6-phosphate receptor (cation dependent) | -2.00825 |
