| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | ampicillin 17.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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106 genes differentially expressed following the CRCGN008_HEPG2_24H:M20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STK10 | serine/threonine kinase 10 | 5.4628 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 5.3034 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 5.29115 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 5.07595 |
| E2F2 | E2F transcription factor 2 | 4.8812 |
| FZD7 | frizzled class receptor 7 | 4.785 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.7127 |
| SMIM40 | small integral membrane protein 40 | 4.45235 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.43453 |
| EGF | epidermal growth factor | 4.29425 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 4.02283 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.8251 |
| VGLL4 | vestigial-like family member 4 | 3.36622 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 3.19015 |
| STIMATE | STIM activating enhancer | 2.91775 |
| EVL | Enah/Vasp-like | 2.8264 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.826 |
| HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | 2.7549 |
| CHN1 | chimerin 1 | 2.7518 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 2.68755 |
| GPATCH8 | G patch domain containing 8 | 2.63415 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 2.5749 |
| CTSL | cathepsin L | 2.4904 |
| VCAM1 | vascular cell adhesion molecule 1 | 2.4598 |
| CCNH | cyclin H | 2.45155 |
| TAC4 | tachykinin 4 (hemokinin) | 2.43555 |
| BBX | bobby sox homolog (Drosophila) | 2.43033 |
| NOSIP | nitric oxide synthase interacting protein | 2.40545 |
| CHEK2 | checkpoint kinase 2 | 2.26303 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | 2.2472 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 | 2.23525 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.21005 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.1937 |
| RETREG3 | reticulophagy regulator family member 3 | 2.18815 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 2.1692 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | 2.16495 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) | 2.15825 |
| HSPA1A | heat shock 70kDa protein 1A | 2.1413 |
| LSP1 | lymphocyte-specific protein 1 | 2.14115 |
| CEP57 | centrosomal protein 57kDa | 2.12417 |
| YIF1A | Yip1 interacting factor homolog A (S. cerevisiae) | 2.1202 |
| COL11A1 | collagen, type XI, alpha 1 | 2.10858 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 2.10535 |
| NCAPH | non-SMC condensin I complex, subunit H | 2.0912 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 2.08805 |
| RHD | Rh blood group, D antigen | 2.0708 |
| TMEM39A | transmembrane protein 39A | 2.06685 |
| BTN2A2 | butyrophilin, subfamily 2, member A2 | 2.06605 |
| LTF | lactotransferrin | 2.0381 |
| WT1 | Wilms tumor 1 | 2.0293 |
| CUZD1 | CUB and zona pellucida-like domains 1 | 2.0289 |
| NSUN5 | NOP2/Sun domain family, member 5 | 2.02367 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.0232 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 | 2.0027 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -8.05555 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.49935 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -4.883 |
| ENOPH1 | enolase-phosphatase 1 | -4.7717 |
| PCNA | proliferating cell nuclear antigen | -4.6007 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -4.5886 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.42945 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -4.4123 |
| MTFR1 | mitochondrial fission regulator 1 | -4.21265 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.053 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | -3.8534 |
| GDF15 | growth differentiation factor 15 | -3.42035 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.1374 |
| SNX11 | sorting nexin 11 | -2.9066 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.8479 |
| CAB39 | calcium binding protein 39 | -2.80485 |
| EVA1B | eva-1 homolog B (C. elegans) | -2.78665 |
| COXFA4L2 | cytochrome c oxidase hypoxia associated subunit FA4L2 | -2.7425 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -2.6999 |
| DBNDD2 | dysbindin (dystrobrevin binding protein 1) domain containing 2 | -2.62955 |
| PUDP | pseudouridine 5'-phosphatase | -2.52155 |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 | -2.49365 |
| NUP54 | nucleoporin 54kDa | -2.4139 |
| YY1AP1 | YY1 associated protein 1 | -2.3619 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | -2.3097 |
| ZNF358 | zinc finger protein 358 | -2.29065 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase | -2.28665 |
| MTMR6 | myotubularin related protein 6 | -2.26175 |
| CHEK1 | checkpoint kinase 1 | -2.2564 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -2.25177 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 | -2.24685 |
| PIAS3 | protein inhibitor of activated STAT, 3 | -2.21025 |
| STS | steroid sulfatase (microsomal), isozyme S | -2.16878 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -2.1484 |
| LY96 | lymphocyte antigen 96 | -2.1292 |
| EBI3 | Epstein-Barr virus induced 3 | -2.10975 |
| PRR16 | proline rich 16 | -2.1054 |
| EXOC3 | exocyst complex component 3 | -2.09485 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -2.0882 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 | -2.08215 |
| DNASE1L1 | deoxyribonuclease I-like 1 | -2.08025 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | -2.0764 |
| POLR1E | polymerase (RNA) I polypeptide E, 53kDa | -2.0598 |
| FAM13A | family with sequence similarity 13, member A | -2.05803 |
| ITPRID2 | ITPR interacting domain containing 2 | -2.0555 |
| MAOA | monoamine oxidase A | -2.04202 |
| TFF3 | trefoil factor 3 (intestinal) | -2.0349 |
| ETHE1 | ethylmalonic encephalopathy 1 | -2.01655 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -2.0123 |
| LTK | leukocyte receptor tyrosine kinase | -2.00895 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | -2.0037 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | -2.00157 |
