CRCGN008_HEPG2_24H:M22 Gene Set
Genes
47 genes differentially expressed following the CRCGN008_HEPG2_24H:M22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
6.08055
|
|
HEBP1
|
heme binding protein 1
|
6.05385
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.1082
|
|
ZFP36
|
ZFP36 ring finger protein
|
4.8367
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.4797
|
|
EPN2
|
epsin 2
|
4.30367
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
3.95233
|
|
FZD7
|
frizzled class receptor 7
|
3.42278
|
|
TBPL1
|
TBP-like 1
|
3.2932
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.09305
|
|
SFTPB
|
surfactant protein B
|
3.01242
|
|
NMU
|
neuromedin U
|
2.96355
|
|
TBP
|
TATA box binding protein
|
2.91795
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.65623
|
|
ECD
|
ecdysoneless homolog (Drosophila)
|
2.54855
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
2.39965
|
|
EVL
|
Enah/Vasp-like
|
2.39345
|
|
KAT6A
|
K(lysine) acetyltransferase 6A
|
2.24058
|
|
NETO2
|
neuropilin (NRP) and tolloid (TLL)-like 2
|
2.21065
|
|
IRF3
|
interferon regulatory factor 3
|
2.17585
|
|
XPO6
|
exportin 6
|
2.12512
|
|
CD55
|
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
|
2.11578
|
|
PLA2G4B
|
phospholipase A2, group IVB (cytosolic)
|
2.00183
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-10.0
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-6.4517
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.0495
|
|
CCDC86
|
coiled-coil domain containing 86
|
-5.01465
|
|
VAT1
|
vesicle amine transport 1
|
-4.9402
|
|
LDHD
|
lactate dehydrogenase D
|
-4.89975
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-4.8726
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-4.74995
|
|
CCNB1
|
cyclin B1
|
-4.04045
|
|
PSMB10
|
proteasome (prosome, macropain) subunit, beta type, 10
|
-3.43055
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-3.36187
|
|
SESN1
|
sestrin 1
|
-2.9348
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.6848
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.67235
|
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
-2.64825
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.61105
|
|
CDS2
|
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
|
-2.5007
|
|
TXNRD1
|
thioredoxin reductase 1
|
-2.45355
|
|
CD58
|
CD58 molecule
|
-2.37922
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.33703
|
|
EPB41L3
|
erythrocyte membrane protein band 4.1-like 3
|
-2.32133
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
-2.2331
|
|
EPHB6
|
EPH receptor B6
|
-2.2191
|
|
OXCT1
|
3-oxoacid CoA transferase 1
|
-2.03455
|
